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Displaying targets 5576 - 5600 of 6103 in total
TargetOrganismDescription# of Drugs
Thymidylate synthasePneumocystis cariniiNot Available2Details
Thymidylate synthaseEscherichia coli (strain K12)Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate ...  more24Details
Thymidylate synthase 1Bacillus subtilis (strain 168)Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate ...  more1Details
ThyroglobulinHumansActs as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). The sy...  more2Details
Thyroid hormone receptorHumans and other mammalsThis group contains thyroid hormone receptors alpha and beta in humans.7Details
Thyroid hormone receptor alphaHumansNot Available1Details
Thyroid hormone receptor alphaHumansNuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroi...  more10Details
Thyroid hormone receptor betaHumansNuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroi...  more17Details
Thyroid peroxidaseHumansIodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4)10Details
Thyrotropin receptorHumansReceptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glyc...  more2Details
Thyrotropin-releasing hormone receptorHumansReceptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G protein-coupled receptor triggers activ...  more6Details
Thyroxine 5-deiodinaseHumansPlays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivat...  more3Details
Thyroxine-binding globulinHumansMajor thyroid hormone transport protein in serum33Details
Tight junction protein 1HumansTJP1, TJP2, and TJP3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins su...  more1Details
TIR domain-containing adapter molecule 1HumansInvolved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to media...  more1Details
Tissue factorHumansInitiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates...  more9Details
Tissue factor pathway inhibitorHumansInhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by for...  more6Details
Tissue-type plasminogen activatorHumansConverts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminog...  more17Details
TNF receptor-associated factor 6HumansE3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin cha...  more1Details
Toll-like receptor 2HumansCooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall co...  more18Details
Toll-like receptor 3HumansKey component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathog...  more4Details
Toll-like receptor 4HumansTransmembrane receptor that functions as a pattern recognition receptor recognizing pathogen- and damage-associated m...  more30Details
Toll-like receptor 5HumansPattern recognition receptor (PRR) located on the cell surface that participates in the activation of innate immunity...  more3Details
Toll-like receptor 6HumansParticipates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated an...  more2Details
Toll-like receptor 7HumansEndosomal receptor that plays a key role in innate and adaptive immunity. Controls host immune response against patho...  more22Details
Displaying targets 5576 - 5600 of 6103 in total