| Tumor necrosis factor | Humans | Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell de... more | 69 | Details |
| Tumor necrosis factor ligand superfamily member 10 | Humans | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also t... more | 2 | Details |
| Tumor necrosis factor ligand superfamily member 11 | Humans | Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augment... more | 5 | Details |
| Tumor necrosis factor ligand superfamily member 12 | Humans | Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B a... more | 1 | Details |
| Tumor necrosis factor ligand superfamily member 13 | Humans | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May ... more | 5 | Details |
| Tumor necrosis factor ligand superfamily member 13B | Humans | Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they ... more | 9 | Details |
| Tumor necrosis factor ligand superfamily member 14 | Humans | Cytokine that binds to TNFRSF3/LTB and TNFRSF14/HVEM and plays major roles in immune system regulation. Upon binding ... more | 2 | Details |
| Tumor necrosis factor ligand superfamily member 15 | Humans | Cytokine that signals through TNFRSF25 receptor. Functions as a T-cell costimulator, that increases IL-2 responsivene... more | 3 | Details |
| Tumor necrosis factor ligand superfamily member 4 | Humans | Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production | 3 | Details |
| Tumor necrosis factor ligand superfamily member 6 | Humans | Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic... more | 1 | Details |
| Tumor necrosis factor receptor | Humans | Not Available | 1 | Details |
| Tumor necrosis factor receptor superfamily member 10A | Humans | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated recept... more | 3 | Details |
| Tumor necrosis factor receptor superfamily member 10B | Humans | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated recept... more | 10 | Details |
| Tumor necrosis factor receptor superfamily member 11A | Humans | Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 p... more | 1 | Details |
| Tumor necrosis factor receptor superfamily member 12A | Humans | Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation... more | 2 | Details |
| Tumor necrosis factor receptor superfamily member 13C | Humans | B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response | 1 | Details |
| Tumor necrosis factor receptor superfamily member 16 | Humans | Low affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. Forms a heterodimeric receptor with SORCS2 that bi... more | 3 | Details |
| Tumor necrosis factor receptor superfamily member 17 | Humans | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of hum... more | 27 | Details |
| Tumor necrosis factor receptor superfamily member 18 | Humans | Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and ... more | 2 | Details |
| Tumor necrosis factor receptor superfamily member 1A | Humans | Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to th... more | 4 | Details |
| Tumor necrosis factor receptor superfamily member 1B | Humans | Receptor with high affinity for TNFSF2/TNF and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxi... more | 1 | Details |
| Tumor necrosis factor receptor superfamily member 4 | Humans | Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity | 6 | Details |
| Tumor necrosis factor receptor superfamily member 5 | Humans | Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cell... more | 12 | Details |
| Tumor necrosis factor receptor superfamily member 6 | Humans | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting ... more | 2 | Details |
| Tumor necrosis factor receptor superfamily member 8 | Humans | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymph... more | 7 | Details |