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Displaying targets 876 - 900 of 6103 in total
TargetOrganismDescription# of Drugs
Bifunctional lipase/adenylate cyclase LipJMycobacterium tuberculosisMay play a role in cell wall modulation. The N-terminal domain exhibits lipolytic activity. In vitro, hydrolyzes vari...  more1Details
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialHumansAlthough its dehydrogenase activity is NAD-specific, it can also utilize NADP at a reduced efficiency2Details
Bifunctional PGK/TIMThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Not Available1Details
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetaseHumansBifunctional phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazole succinocarboxamide synthetase ...  more1Details
Bifunctional polymyxin resistance protein ArnAEscherichia coli (strain K12)Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-ara...  more2Details
Bifunctional protein GlmUEscherichia coli (strain K12)Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcN...  more3Details
Bifunctional protein GlmUHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcN...  more1Details
Bifunctional protein GlmUStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcN...  more1Details
Bifunctional protein MdtAMethylobacterium extorquens (strain ATCC 14718 / DSM 1338 / AM1)Catalyzes the dehydrogenation of methylene-H(4)MPT. Can also catalyze the reversible dehydrogenation of methylene-H(4...  more1Details
Bifunctional protein PutAEscherichia coli (strain K12)Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional represso...  more3Details
Bifunctional protein PyrRBacillus caldolyticusRegulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent man...  more3Details
Bifunctional purine biosynthesis protein ATICHumansBifunctional enzyme that catalyzes the last two steps of purine biosynthesis. Acts as a transformylase that incorpora...  more8Details
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseHumansBifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities...  more2Details
Bile acid receptorHumansLigand-activated transcription factor. Receptor for bile acids (BAs) such as chenodeoxycholic acid (CDCA), lithocholi...  more26Details
Bile acid-CoA:amino acid N-acyltransferaseHumansCatalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-...  more2Details
Bile acidsHumansNot Available6Details
Bile salt export pumpHumansCatalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid acros...  more124Details
Bile salt hydrolase/transferaseClostridium perfringens (strain 13 / Type A)Possesses dual functions in bile acid metabolism. Acts as a bile salt hydrolase that catalyzes the deconjugation of g...  more4Details
Bile salt-activated lipaseHumansCatalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids...  more5Details
Biliverdin reductase AHumansReduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IXalpha, to bilirubin with the concomitant oxid...  more3Details
Biotin biosynthesis cytochrome P450Bacillus subtilis (strain 168)Catalyzes the C-C bond cleavage of fatty acid linked to acyl carrier protein (ACP) to generate pimelic acid for bioti...  more1Details
Biotin carboxylaseEscherichia coli (strain K12)This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the car...  more11Details
Biotin synthaseEscherichia coli (strain K12)Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a ra...  more1Details
Biotin--protein ligaseHumansBiotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, py...  more1Details
Biotin/lipoyl attachment proteinBacillus subtilis (strain 168)Not Available1Details
Displaying targets 876 - 900 of 6103 in total