facilitation of small bowel intubation therapy (DBCOND0022943)

Identifiers

Synonyms

To facilitate intubation / Facilitation of small bowel intubation / Intubation, Intratracheal / Endotracheal intubation NOS / Endotracheal intubation / Insertion of endotracheal tube (procedure) / Endotracheal tube insertion / Tracheal intubation / Endotracheal intubation NOS (procedure)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Atracurium besylate	A non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery.	Neuronal acetylcholine receptor subunit alpha-2target
Metoclopramide	An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.	Muscarinic acetylcholine receptor M1target D(2) dopamine receptortarget Cytochrome P450 2D6enzyme 5-hydroxytryptamine receptor 4target 5-hydroxytryptamine receptor 3Atarget Cytochrome P450 3A4enzyme Cytochrome P450 1A2enzyme ATP-dependent translocase ABCB1transporter Alpha-1-acid glycoprotein 1carrier
Mivacurium	A short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation.	Neuronal acetylcholine receptor subunit alpha-2target Muscarinic acetylcholine receptor M2target Muscarinic acetylcholine receptor M3target Cholinesterasetarget Cholinesteraseenzyme
Pancuronium	A neuromuscular blocker used as an adjunct to general anesthesia to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.	Neuronal acetylcholine receptor subunit alpha-2target Cholinesteraseenzyme Muscarinic acetylcholine receptor M2target Muscarinic acetylcholine receptor M3target Solute carrier family 22 member 1transporter Solute carrier family 22 member 2transporter
Rocuronium	A vecuronium analog used to facilitate tracheal intubation and to relax skeletal muscles during surgery.	Neuronal acetylcholine receptor subunit alpha-2target Muscarinic acetylcholine receptor M2target 5-hydroxytryptamine receptor 3Atarget Solute carrier family 22 member 1transporter Solute carrier organic anion transporter family member 1A2transporter
Vecuronium	A nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.	ATP-dependent translocase ABCB1transporter Neuronal acetylcholine receptor subunit alpha-2target

Clinical Trials

Not Available