Macular Degeneration (DBCOND0027875)

Identifiers

Synonyms
Macular degeneration / Macula lutea degeneration / Retinal macula lutea degeneration / Macular luteal degeneration / Degenerative disorder of macula (disorder) / Degeneration macular

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00656903
High Speed Indocyanine Green Angiography Findings in Ranibizumab Treatment for Wet Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT00101764
Intravitreal v. Sub-tenon Injections of Triamcinolone Acetonide for Macular Edema in Retinal Disorderstreatment1completed
NCT00078221
Rheopheresis Blood Filtration Study for the Treatment of Dry Age-Related Macular Degeneration (AMD)No drug interventionstreatment3unknown_status
NCT04008121
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodiumdiagnostic0not_yet_recruiting
NCT00804921
Effectiveness of Oral Acetazolamide, Brimonidine Tartarate, and Anterior Chamber Paracentesis in Intraocular Pressure (IOP) After BevacizumabNot Available2completed
NCT00150202
Clinical Study Of EYE001 For Wet-Type AMD (Age-Related Macular Degeneration)treatment3completed
NCT00492284
Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL)treatment2completed
NCT00996684
Study of Intravitreal Microplasmin in Relieving Vitreo-Macular Adhesion in Neovascular Age-related Macular Degenerationtreatment2unknown_status
NCT01653184
Effect of Omega-3-fatty Acids on Blood Levels Omega-3 Fatty Acids in Patients With Age-related Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT00722384
Open Label Study for the Evaluation of Tolerability of Five Dose Levels of Cand5treatment1completed
NCT00896779
Lucentis in Advanced Macular Degenerationtreatment2completed
NCT00050479
Laser and Medical Treatment of Diabetic Macular Edematreatment3completed
NCT03732287
Cooling Anesthesia for Intravitreal InjectionNo drug interventionstreatment1 / 2completed
NCT01245387
Observational Study Of The Long-Term Effect Of Macugen In Patients With Wet Age-Related Macular DegenerationNot AvailableNot Availablecompleted
NCT00385333
Metabolic Mapping to Measure Retinal MetabolismNo drug interventionsdiagnostic2completed
NCT02540954
Efficacy and Safety of Two Different Aflibercept Regimens in Subjects With Neovascular Age-related Macular Degeneration (nAMD)treatment3completed
NCT06224751
Developing Better Computerised Vision Tests (CVTV)No drug interventionsNot AvailableNot Availablerecruiting
NCT04658251
Study of New Mutations in Cone DisordersNo drug interventionsNot AvailableNot Availablerecruiting
NCT00727753
VEGF-antagonism and Endothelial Function in Age-related Macular Degeneration (AMD)Not AvailableNot Availablecompleted
NCT00436553
Efficacy/Safety of Verteporfin Photodynamic Therapy and Ranibizumab Compared With Ranibizumab in Patients With Subfoveal Choroidal Neovascularizationtreatment3completed
NCT00308477
A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Branch Retinal Vein Occlusiontreatment1 / 2completed
NCT02390245
Philadelphia Telemedicine Glaucoma Detection and Follow-Up StudyNo drug interventionsotherNot Availablecompleted
NCT00000145
Age-Related Eye Disease Study (AREDS)No drug interventionstreatment3completed
NCT01024998
Safety and Tolerability Study of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration (AMD)No drug interventionstreatment1completed
NCT02659098
A Study to Evaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic Atrophytreatment2completed
NCT00426998
Combination Bevacizumab and Verteporfin (Two Different Sequences of Treatment)in Neovascular AMDtreatment2completed
NCT00220805
Use of Immune Globulin Intravenous (Human) To Treat Age-Related Macular Degenerationtreatment2completed
NCT01494805
Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular DegenerationNo drug interventionstreatment1 / 2completed
NCT00041483
Phase 3 Study to Evaluate Anecortave Acetate vs. Visudyne for the Treatment of the Wet Form of AMDtreatment3completed
NCT00065728
Open-Label Posterior Juxtascleral Injections of Anecortave Acetate 15mg Dose for Long Term Use in Patients With AMDtreatment3terminated
NCT05100511
Fundus Image-guided Focal Electroretinography, Usability StudyNo drug interventionsotherNot Availablecompleted
NCT00570193
Photodynamic and Pharmacologic Treatment of CNVtreatment1 / 2completed
NCT03846193
FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMDNo drug interventionstreatment1 / 2terminated
NCT00320788
Safety and Efficacy of Repeated Intravitreal Administration of Vascular Endothelial Growth Factor (VEGF) Trap in Patients With Wet Age-Related Macular Degeneration (AMD)treatment2completed
NCT00121407
Visudyne® in Occult (VIO)treatment3completed
NCT00100009
Triamcinolone Acetonide Plus Laser Therapy to Treat Age-Related Macular Degenerationtreatment3completed
NCT03946085
Evaluation of a New Eye-specific Multivitamin Formula in Participants at Risk of Age-related Macular Degeneration (AMD)No drug interventionspreventionNot Availablecompleted
NCT05130385
High Resolution Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00008515
Fluocinolone Implant to Treat Macular Degenerationtreatment1completed
NCT02895815
Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD)treatment2withdrawn
NCT00102115
Study of Talaporfin Sodium Photodynamic Therapy to Treat Advanced Age Related Macular Diseasetreatment1terminated
NCT00877032
Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular DegenerationNo drug interventionsprevention1completed
NCT02420132
Study to Evaluate Home Vision Testing in Participants Who Receive Ranibizumab (Lucentis®)No drug interventionsNot AvailableNot Availablecompleted
NCT03335852
Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Japanese Patients With Neovascular AMDtreatment1completed
NCT00000152
Randomized Trial of Beta-Carotene and Macular Degenerationprevention3unknown_status
NCT01933152
Study to Assess the EffectiVeness of exIsting Anti-vascular Endothelial groWth Factor (Anti-VEGF) Treatment Regimens in Patients With Wet Age-related Macular DegenerationNot AvailableNot Availablecompleted
NCT00465400
Oxidative Stress in Patients With Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT05439759
Factors in Learning And Plasticity: Healthy VisionNo drug interventionsbasic_scienceNot Availablerecruiting
NCT02313259
The Impact of Ocular Diseases on Driving: a Prospective StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT00320775
Safety and Tolerability Study of Intravitreal VEGF-Trap Administration in Patients With Neovascular AMDtreatment1completed
NCT00527475
Ranibizumab and Reduced Fluence PDT for AMDtreatment2completed
NCT01746875
A Study Testing if Medicine Can Make Pigment Epithelium Detachments Regress and Stabilize the Vision in EyespreventionNot Availableterminated
NCT00327470
An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMDtreatment4terminated
NCT00403442
Bevacizumab in Combination With Verteporfin Reduced and Standard Fluence in the Treatment of Hemorrhaged Lesions in Neovascular AMDNo drug interventionstreatment1terminated
NCT04428242
Study Evaluating Retinal Health Monitoring System Thickness ModuleNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03804099
Effect Aflibercept on Ocular Perfusiontreatment4completed
NCT00414999
A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteerstreatment1completed
NCT00414206
Safety and Efficacy of ATG003 in Patients With Wet Age-Related Macular Degeneration (AMD)treatment2terminated
NCT02941406
MP3 (Microperimeter 3) Reproducibility in Healthy Subjects and Macular PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00523406
Comparison of Reduced Fluence Versus Standard Photodynamic Therapy (in Combination With Intravitreal Triamcinolone Acetate)No drug interventionstreatment3completed
NCT01339949
Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)No drug interventionstreatmentNot Availablewithdrawn
NCT03539549
A Study to Evaluate Abicipar Pegol for Safety and Treatment Effect in Participants With Neovascular Age-related Macular Degeneration (AMD)treatment2completed
NCT04640649
Prediction of Progression of Age-Related Macular DegenerationNo drug interventionsdiagnosticNot Availableunknown_status
NCT00531336
MAAM Study: Avastin and Macugen Versus Avastin Versus Macugentreatment2completed
NCT00021736
Phase II/III Study of Anti-VEGF in Neovascular AMDtreatment2 / 3completed
NCT02067013
Analysis of Aqueous and Vitreous Humorbasic_science2unknown_status
NCT00668213
Antioxidant Systems and Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT02689518
EAGLE: Evaluating Genotypes Using Intravitreal Aflibercept Injectiontreatment4completed
NCT02225119
The Focal Electro-Oculogram in Macular DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03411941
Evaluate the Effectiveness of Intravitreal (IVT) Aflibercept Injection in Clinical Practice in naïve Patients With Neovascular Age-related Macular Degeneration (nAMD)Not AvailableNot Availablecompleted
NCT00531141
The Optical Coherence Tomography in Age-Related Macular Degeneration Study: The OCT in AMD StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT03011541
Stem Cell Ophthalmology Treatment Study IINo drug interventionstreatmentNot Availablerecruiting
NCT02332941
Treatment -Resistant Neovascular Age-Related Macular Degenerationtreatment1completed
NCT05675917
MacuTest Website for Personalized AMD Risk Prediction and PreventionNo drug interventionspreventionNot Availablewithdrawn
NCT02749734
Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration DiseasesNo drug interventionstreatment1 / 2unknown_status
NCT00559234
Potential Research Participants for Future Studies of Inherited Eye DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT05454124
Factors in Learning And Plasticity: Macular DegenerationNo drug interventionsbasic_scienceNot Availablerecruiting
NCT04685824
Visual Telerehabilitation in AMD PatientsNo drug interventionssupportive_careNot Availableterminated
NCT00531024
Systemic Avastin Therapy in Age-Related Macular Degenerationtreatment2 / 3completed
NCT04714424
Comparing Vision Tests in a Virtual Reality Headset to Existing AnaloguesNo drug interventionsNot AvailableNot Availablecompleted
NCT02868424
Treatment of Age-related Macular Degeneration by Fetal Retinal Pigment Epithelial Cells TransplantationNo drug interventionstreatment0unknown_status
NCT00324116
Evaluation Of Safety And Efficacy Of 0.3 Mg/Eye Macugen In Patients With Small Age-Related Macular Degeneration Lesionstreatment4completed
NCT02615496
Evaluation of Physician and Patient Knowledge of Safety and Safe Use Information for AfliberceptNo drug interventionsNot AvailableNot Availablecompleted
NCT00032396
A Study to Evaluate Retisert in the Treatment of Patients With the "Wet" Form of Age-Related Macular Degenerationtreatment2unknown_status
NCT02686658
Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degenerationtreatment2 / 3completed
NCT00976235
A Long-Term Monitoring Study of the IMT-002 PatientsNo drug interventionsotherNot Availablecompleted
NCT00087763
Pegaptanib Sodium on Foveal Thickening in Patients With Exudative Subfoveal Age-Related Macular Degeneration (AMD)treatment2completed
NCT02462486
Safety and Efficacy of Abicipar Pegol in Participants With Neovascular Age-related Macular Degenerationtreatment3completed
NCT01783925
Eylea Post Marketing Surveillance(PMS)Not AvailableNot Availablecompleted
NCT00784225
S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000prevention3completed
NCT03815825
GOLDEN STUDY: A Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRx in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)No drug interventionstreatment2completed
NCT00089830
A Safety and Efficacy Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular Degenerationtreatment2terminated
NCT01756248
EYLEA Age-Related Macular Degeneration (AMD) Post-marketing Surveillance in JapanNot AvailableNot Availablecompleted
NCT00509548
Open-Label, Pilot Study of TG100801 in Patients With Choroidal Neovascularization Due to AMDtreatment2terminated
NCT01362348
12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD)treatment2terminated
NCT01521065
An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovascularization Secondary to Age-related Macular DegenerationNo drug interventionstreatment2unknown_status
NCT01115231
Complement Factor H Haplotypes and Smoking in Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablecompleted
NCT06074731
Diagnostic Possibilities in Ophthalmological Diseases Using Swept Source Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablerecruiting
NCT02032173
Efficacy and Safety of Lucentis® Use in Patients With Diabetic Macular Edema Evaluating a Spaced Out Follow-up After Intensive Treatment Phasetreatment3terminated
NCT01632527
Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD)No drug interventionstreatment1 / 2completed
NCT00071227
Eye Injections of Triamcinolone Acetonide for Retinal Blood Vessel Disorderstreatment1completed
NCT00157976
Double-Masked Study of Photrex (Rostaporfin) Photodynamic Therapy in the Treatment of Age-Related Macular Degenerationtreatment3unknown_status
NCT00058994
An Evaluation of Safety and Efficacy of Anecortave Acetate Versus Placebo in Patients With Subfoveal CNV Due to Exudative AMDtreatment3completed
NCT04684394
A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degenerationtreatment2terminated
NCT00813891
Efficacy of Ranibizumab in Combination With Photodynamic Therapy for Wet Age-Related Macular Degenerationtreatment4unknown_status
NCT04141891
Advancing Understanding of Transportation OptionsNo drug interventionshealth_services_researchNot Availablecompleted
NCT00000162
Branch Vein Occlusion StudyNo drug interventionstreatment3completed
NCT00043680
Celecoxib to Treat Macular Degeneration in Patients Receiving Photodynamic Therapytreatment2completed
NCT00454389
A Study of Strontium90 Beta Radiation With Lucentis to Treat Age-Related Macular Degenerationtreatment3unknown_status
NCT01655589
VEGF Gene Association With Response to Neovascular Age-related Macular Degeneration With Anti-VEGF AgentsNo drug interventionsNot AvailableNot Availableunknown_status
NCT01748292
Treat & Extend Treatment With 0.5mg Ranibizumab vs Monthly Treatment With 0.5mg Ranibizumabtreatment3completed
NCT00769392
Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal InjectiontreatmentNot Availablecompleted
NCT00041444
Multi-Ethnic Study of Atherosclerosis (MESA) - Ancillary Eye StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01920867
Stem Cell Ophthalmology Treatment StudyNo drug interventionstreatmentNot Availableunknown_status
NCT05571267
Safety Study of Zimura™in Combination With Anti-VEGF Therapy in Patients With Neovascular AMDtreatment2terminated
NCT00000167
Complications of Age-Related Macular Degeneration Prevention TrialNo drug interventionsprevention3completed
NCT00733304
An Extension to Study MD7108240treatment2completed
NCT02181504
A Study of Abicipar Pegol in Japanese Patients With Neovascular Age-related Macular Degenerationtreatment2completed
NCT04270604
Biological Sample Collection for Research and BiobankingNo drug interventionsNot AvailableNot Availableterminated
NCT04111068
Improving Vision in Adults With Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT04762368
Learning Study: Improving Vision in Adults With Macular DegenerationNo drug interventionstreatmentNot Availablerecruiting
NCT02747368
Evaluation of Visual Function and Driving Health Using Ocusweep in Patients Suffering From Wet Age-related Macular DegenerationNo drug interventionsscreeningNot Availableunknown_status
NCT02558712
Technology-based Eye Care Services (TECS) CompareNo drug interventionsdiagnosticNot Availablecompleted
NCT05456581
Scotoma Perimetry Oculomotor TrainingNo drug interventionsbasic_scienceNot Availablerecruiting
NCT00001395
Long Term Follow-Up of Diabetic RetinopathyNo drug interventionsNot AvailableNot Availablecompleted
NCT06583395
Quest to Analyze One Thousand Humans MeditatingNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03521895
An Integrated Analysis of the Effectiveness of Intravitreal (IVT) Aflibercept (Eylea) in Routine Clinical Practice Based on Two Large Observational StudiesNot AvailableNot Availablecompleted
NCT01134055
Dose Ranging Study of Pazopanib to Treat Neovascular Age-Related Macular Degenerationtreatment2completed
NCT05637255
A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular Age-related Macular Degeneration (AMD)No drug interventionstreatment2recruiting
NCT00659555
Study Of The Repeat Dosing Of Ketoconazole On The Pharmacokinetics Of A Single Dose Of Pazopanib (GW786034) Eye Dropstreatment1completed
NCT00000150
Submacular Surgery Trials (SST)No drug interventionstreatment3completed
NCT00090623
A Study of rhuFab V2 (Ranibizumab) in Subjects With Subfoveal Choroidal Neovascularization Secondary to Age-Related Macular Degeneration (AMD)treatment3completed
NCT02264938
Drusen Morphology Changes in Nonexudative Age-related Degeneration After Oral Antioxidants SupplementationNo drug interventionspreventionNot Availablecompleted
NCT00538538
Subretinal Lucentis for Hemorrhagic Age-related Macular Degeneration (AMD)treatment1withdrawn
NCT00735943
Macugen Observational StudyNo drug interventionsNot AvailableNot Availableterminated
NCT00605943
Detection of Neutralizing Antibodies in Patients Treated With Bevacizumab or RanibizumabNo drug interventionsNot AvailableNot Availablecompleted
NCT04567303
Study of Zifibancimig in Participants With Neovascular Age-Related Macular Degenerationtreatment1 / 2recruiting
NCT00343603
Tracking Optical Coherence TomographyNo drug interventionsNot AvailableNot Availablecompleted
NCT04499703
Evaluation of the Retinal Health Monitoring System Thickness ModuleNo drug interventionsNot AvailableNot Availablecompleted
NCT03470103
A Study in Patients With Wet Age-related Macular Degeneration or Diabetic Macular Edema to Assess the freQuency of Use of Intravitreal Aflibercept in Routine Clinical Practices in Latin AmericaNot AvailableNot Availablecompleted
NCT00499590
Safety & Efficacy Study Evaluating the Combination of Bevasiranib & Lucentis Therapy in Wet AMDtreatment3terminated
NCT03603990
Effect of Vitrectomy on the Evolution of Refractory Diabetic Macular EdemaNo drug interventionstreatmentNot Availablewithdrawn
NCT00359164
Phase II Pilot Study of Visudyne® Photodynamic Therapy (PDT) (Low and Very Low Fluence) Combined With Bevacizumab.treatment2completed
NCT00006202
Lutein for Age-Related Macular Degenerationtreatment2completed
NCT02486484
Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injectiontreatment2unknown_status
NCT00100087
Safety Study for Treatment of Wet Macular Degeneration Using the TheraSight(TM) Ocular Brachytherapy SystemNo drug interventionstreatment1 / 2unknown_status
NCT00095433
Extension Study of rhuFab V2 in Subjects With Neovascular Age-Related Macular Degeneration (AMD)treatment3completed
NCT00001733
Screening for Studies on Retinovascular DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT01773954
Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular DegenerationtreatmentNot Availablecompleted
NCT00447954
A Study of an Encapsulated Cell Technology (ECT) Implant for Patients With Atrophic Macular Degenerationtreatment2completed
NCT02090751
Development of a Device to Measure Dark AdaptationNo drug interventionsNot AvailableNot Availablecompleted
NCT00312351
A Clinical Trial to Explore the Safety and Efficacy of Three Different Doses of Pegaptanib Sodium in Patients With Wet Age-Related Macular Degeneration (AMD)treatment4terminated
NCT00259753
Safety and Efficacy Study of Small Interfering Ribonucleic Acid (RNA) Molecule (Cand5) to Treat Wet Age-Related Macular Degenerationtreatment2completed
NCT00684853
Intravitreal Bevacizumab Combined With PDT Versus Bevacizumab to Treat Exudative AMDtreatment2unknown_status
NCT00637377
Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD)treatment3completed
NCT02157077
Aflibercept After Ranibizumab in Exudative Age-related Macular Degenerationtreatment3completed
NCT01831947
Efficacy Study of Ranibizumab on Patients With Age-related Macular Degeneration.treatment4completed
NCT02821247
Prospective Observational Study to Assess Effectiveness of Intravitreal Aflibercept in Patients With Wet Macular Degeneration in GreeceNot AvailableNot Availablecompleted
NCT03956797
Long Term Safety of Cooling Anesthesia for Intravitreal InjectionNo drug interventionstreatmentNot Availablecompleted
NCT01756261
EYLEA [AMD-QOL(Age-Related Macular Degeneration-Quality of Life)] Post-marketing Surveillance in JapanNot AvailableNot Availablecompleted
NCT00000161
Randomized Trials of Vitamin Supplements and Eye Diseaseprevention3unknown_status
NCT02462928
A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degenerationtreatment3completed
NCT00239928
Clinical Study Of Pegaptanib Sodium (EYE001) For Wet-Type Age-Related Macular Degenerationtreatment2completed
NCT00042211
Preventing Depression in Patients With Macular DegenerationNo drug interventionsprevention3completed
NCT00745511
Pilot Study to Evaluate the Safety and Efficacy of Treatment With ORA102 Combined With Avastin (Bevacizumab) Versus Avastin Alone, in Patients With Neovascular Age Related Macular Degeneration (AMD)treatment1 / 2unknown_status
NCT02827071
Ocular Imaging Study Using Advanced OCTNo drug interventionsNot AvailableNot Availableunknown_status
NCT04988178
Analysis of naïve Patients With Age-related Macular Degeneration Neovascular Type and Treated With Ranibizumab (Lucentis®) in Treat-and-extend at the CHU Brugmann.No drug interventionsNot AvailableNot Availablecompleted
NCT02222207
Regorafenib Eye Drops: Investigation of Efficacy and Safety in Neovascular Age Related Macular Degenerationtreatment2terminated
NCT00395707
Study To Determine Safety/Efficacy of Lucentis For Treatment Of Retinal Angiomatous Proliferation Secondary To Age Related Macular Degenerationtreatment1 / 2completed
NCT00299507
Anecortave Acetate in Patients With Exudative Age-related Macular Degeneration (AMD)treatment3completed
NCT03105609
Enhancing the Lucentis (Ranibizumab) Management of Choroidal Neovascular Membranes With Hyperspectral ImagingNo drug interventionsNot AvailableNot Availableterminated
NCT01021956
Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMDNo drug interventionstreatment2terminated
NCT00612456
To Evaluate the Pharmacodynamics, Safety, and Pharmacokinetics of Pazopanib Drops in Adult Subjects With Neovascular AMDtreatment2completed
NCT02087085
A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degenerationtreatment2terminated
NCT00001615
Phase I Study of Corticosteroid Treatment of Ill-Defined Choroidal Neovascularization in Age-Related Macular DegenerationNo drug interventionstreatment1completed
NCT06262737
Single-center Study Measuring OSDI Dry Eye Score in Patients Undergoing an Anti-VEGF Induction ProtocolNo drug interventionsNot AvailableNot Availablerecruiting
NCT01025232
A Study of Intravitreal Injections of 2.0mg Ranibizumab in Subjects With Chronic Fluid On OCT Post Multiple Injections With Ranibizumab (Super-dose Anti-VEgf SAVE Trial)treatment1 / 2terminated
NCT06394232
Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.treatment1 / 2recruiting
NCT06198452
Vision Improvement for Patients With Age-Related Macular DegenerationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00469352
A Study of Genetic and Environmental Factors and Their Effect on Response to Treatment With Lucentis (Ranibizumab) for Wet AMDtreatment3completed
NCT06511700
Implementation of the Intravitreal Injection Administered by NursesNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT01600300
Efficacy of Electrical Micro-current Retinal Stimulation for Treatment of Dry Age-related Macular DegenerationNo drug interventionstreatment1 / 2completed
NCT01051700
A Safety Study in Healthy Volunteers to Evaluate Safety, How Fast the Drug is Absorbed, and the Side Effects of the Drug in Humanssupportive_care1completed
NCT03805100
Comparing the Efficacy and Safety of Biosimilar Candidate Xlucane Versus Lucentis® in Patients With nAMDtreatment3completed
NCT02348359
X-82 to Treat Age-related Macular Degenerationtreatment2terminated
NCT00018070
Identification and Treatment of Feeder Vessels in Macular DegenerationNo drug interventionstreatment1completed
NCT00109499
Study of AdGVPEDF.11D in Neovascular Age-related Macular Degeneration (AMD)No drug interventionstreatment1completed
NCT06203106
NYSCF Scientific Discovery BiobankNo drug interventionsNot AvailableNot Availablerecruiting
NCT00060749
Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophytreatment1completed
NCT00709449
An Open Study Comparing the Effects of Moxaverine on Ocular Blood Flow in Patients With Age- Related Macular Degeneration, Primary Open Angle Glaucoma and Healthy Control Subjectstreatment2 / 3completed
NCT03318549
BCI and Evaluation of Visual and Task Performance in Subjects With Eye DiseasesNo drug interventionsdiagnosticNot Availablecompleted
NCT00444249
Influence of Blue Light Filtering Intraocular Lenses on Daytime Levels of MelatoninNo drug interventionsdiagnosticNot Availableterminated
NCT00056836
A Study to Evaluate rhuFab V2 in Subjects With Minimally Classic or Occult Subfoveal Neovascular Macular Degenerationtreatment3completed
NCT00926913
Investigating Optical and Neural Causes of Vision LossNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01189019
HiPED - High Dose Lucentis for Persistent Pigment Epithelial Detachments in Age-related Macular Degenerationtreatment2terminated
NCT00658619
Safety and Efficacy of Brimonidine Intravitreal Implant in Patients With Geographic Atrophy Due to Age-related Macular Degeneration (AMD)treatment2completed
NCT01204541
A Single-Center Pilot Study to Assess Macular FunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT05283941
Pistachios and Neural Macular PigmentNo drug interventionspreventionNot Availablerecruiting
NCT05839041
A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)No drug interventionstreatment2recruiting
NCT03133117
Deficits, Adaptation and Cerebral Functional Reorganization of Visual Retinotopic Treatments During Normal and Pathological Aging (Age-related Macular Degeneration and Glaucoma)No drug interventionsbasic_scienceNot Availableterminated
NCT02181517
A Study of Abicipar Pegol in Patients With Neovascular Age-related Macular Degenerationtreatment2completed
NCT00433017
Verteporfin Photodynamic Therapy Administered in Conjunction With Ranibizumab in Patients With Subfoveal Choroidal Neovascularization Secondary to Age-related Macular Degeneration (AMD)treatment2 / 3terminated
NCT00536016
A Phase 1 Safety Study of Single and Repeated Doses of JSM6427 (Intravitreal Injection) to Treat AMDtreatment1completed
NCT06305416
A Efficacy and Safety Study of Ranibizumab 10mg/ml Injection (Incepta) in Patients With Diabetic Macular Edematreatment3recruiting
NCT05797896
Investigating Geographic Atrophy Insights (i-GAIN) Natural History StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00000158
Macular Photocoagulation Study (MPS)No drug interventionstreatment3unknown_status
NCT00211458
Treatment of Age-Related Macular Degeneration With Anecortave Acetatetreatment2completed
NCT00467935
Scotoma Reduction in AMD Patients Treated With Ranibizumabtreatment1 / 2completed
NCT05445063
Safety and Efficacy of Autologous Transplantation of iPSC-RPE in the Treatment of Macular DegenerationNo drug interventionstreatment1recruiting
NCT04741763
"Night Vision and Carotenoids"No drug interventionssupportive_careNot Availablecompleted
NCT04643886
A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular DegenerationNo drug interventionstreatment2terminated
NCT00349739
Treatment of Patients With Age-Related Macular Degeneration With Anecortave AcetateNot AvailableNot Availableno_longer_available
NCT00478530
The Effect of Intravitreal Avastin on the Retina Measured by ElectroretinogramNo drug interventionstreatmentNot Availablecompleted
NCT02806830
Ocular Discomfort Assessment After Intravitreal InjectionsNo drug interventionssupportive_careNot Availablecompleted
NCT00709657
The Effect of a Single Intravitreal Anti-VEGF Therapy on Optic Nerve Head Perfusionbasic_scienceNot Availableterminated
NCT03954626
Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMDtreatment3completed
NCT05566626
Retinal Oxygenation Estimation Trial With Mantis Photonics Hyperspectral CameradiagnosticNot Availableenrolling_by_invitation
NCT04246866
First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular DegenerationNo drug interventionstreatment1completed
NCT03725566
JY028 Single Vitreous Injection in a Phase 1 Clinical Trial in nAMD PatientsNo drug interventionsotherNot Availableunknown_status
NCT04435366
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)treatment3completed
NCT02859766
Safety and Pharmacokinetics of Abicipar Pegol Intravitreal Injections in Patients With Neovascular AMDtreatment1completed
NCT00533520
Evaluation of Dosing Interval of Higher Doses of Ranibizumabtreatment4completed
NCT00463320
A Study To Evaluate The Safety, Tolerability And Pk Of Pazopanib Eye Drops In Healthy Adult And Elderly Subjects.diagnostic1completed
NCT03894020
GTSCOPE - To Evaluate the Natural Progression of Dry Age-related Macular Degeneration (AMD)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00094120
MSI-1256F (Squalamine Lactate) in Combination With Verteporfin in Patients With "Wet" Age-Related Macular Degeneration (AMD)treatment2terminated
NCT00695682
Intravitreal Infliximab for Diabetic Macular Edema (DME) and Choroidal Neovascularization (CNV)treatment1unknown_status
NCT01941082
A Study of RO6867461 Administered in Single- and Multiple-Ascending Doses in Patients With Wet Age-Related Macular Degenerationtreatment1completed
NCT00447031
Combination Therapy for Neovascular Age Related Macular DegenerationtreatmentNot Availablewithdrawn
NCT01016873
INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMDNo drug interventionstreatment2completed
NCT00845273
Long-Term Use Of Pegaptanib In Patients For Subfoveal Choroidal Neovascularization Secondary To Age-Related Macular DegenerationNot AvailableNot Availablecompleted
NCT00333476
A Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular DegenerationNot Available2terminated
NCT00466076
Copaxone in Age Related Macular Degenerationtreatment2 / 3unknown_status
NCT02510794
Study of the Efficacy and Safety of the Ranibizumab Port Delivery System for Sustained Delivery of Ranibizumab in Patients With Subfoveal Neovascular Age-Related Macular Degenerationtreatment2completed
NCT00061594
A Study to Compare rhuFab V2 With Verteporfin Photodynamic in Treating Subfoveal Neovascular Macular Degenerationtreatment3completed
NCT01003691
Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Including Geographic AtrophyNo drug interventionstreatment1completed
NCT01749891
A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degenerationtreatment1 / 2completed
NCT02581891
Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eyetreatment4completed
NCT01154062
A Study to Evaluate Pazopanib Tablets in Patients Who Have Neovascular Age-related Macular Degenerationtreatment1completed
NCT01217762
Safety & Tolerability of the IRay System in Subjects With Exudative Choroidal Neovascularization (CNV) Secondary to Age-Related Macular Degeneration (AMD)No drug interventionstreatment1unknown_status
NCT00242580
A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of Intravitreal Triamcinolone Acetonide and the Verteporfin Therapy Plus Intravitreal Pegaptanibtreatment3completed
NCT00619229
Alprostadil in Maculopathy Study (AIMS)treatment3terminated
NCT00051129
Anecortave Acetate in Subfoveal Choroidal Neovascularization (CNV) Due to Wet Age-Related Macular Degeneration (AMD)treatment3completed
NCT02543229
Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of OPT-302 With or Without Lucentis™ in Patients With Wet AMDtreatment1completed
NCT00708929
Does Complement Factor H Gene Polymorphism Play a Role in the Regulation of Vascular Tone in the Choroid?No drug interventionsbasic_scienceNot Availablecompleted
NCT00121589
Lutein/Zeaxanthin and Omega-3 Supplementation in Persons Over Age 60treatment1completed
NCT02569892
Non-Damaging Photothermal Therapy of Non-exudative Age Related Macular DegenerationNo drug interventionstreatmentNot Availablecompleted
NCT00088192
Intravitreous Pegaptanib Sodium Injection in Patients With Exudative Age-Related Macular Degeneration (AMD)treatmentNot Availablecompleted
NCT05904444
The Effect of Duration Between Sessions on Microperimetric Biofeedback Training in Patients With MaculopathiesNo drug interventionstreatmentNot Availablecompleted
NCT02452840
Photodynamic Therapy for PDA in NV AMDNo drug interventionsNot AvailableNot Availablecompleted
NCT01213667
Genetics in Non-response to Anti-VEGF Treatment in Exudative AMDtreatment4unknown_status
NCT05147701
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Eye DiseasesNo drug interventionstreatment1recruiting
NCT02228304
Study of the Intravitreal Implantation of NT-503-3 Encapsulated Cell Technology (ECT) for the Treatment of Recurrent Choroidal Neovascularization (CNV) Secondary to Age-related Macular Degeneration (AMD)treatment1 / 2terminated
NCT00380172
Long-Term Efficacy in AMD of Rheopheresis in North AmericaNo drug interventionstreatmentNot Availableunknown_status
NCT03438669
Correlation Between Visual Acuity Measurements, Quality of Life and Morphological Parameters in Wet AMD PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00001346
Diabetic Retinopathy and Visual Function StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT01482910
VEGF Trap-Eye: Investigation of Efficacy and Safety in Chinese Subjects With Wet AMD (Age-Related Macular Degeneration)treatment3completed
NCT04002310
A Study to Test How Well Different Doses of BI 754132 Are Tolerated in Patients With an Advanced Form of Age-related Macular Degeneration Called Geographic AtrophyNo drug interventionstreatment1terminated
NCT03614481
Clinical and Genetic Analyzes of Age-related Macular DegenerationNo drug interventionsNot AvailableNot Availablerecruiting
NCT01771081
Evaluation of Changes in Visual Acuity in Patients With Diabetic Macular Edema (DME) Starting Treatment With an Approved Anti-VEGF TherapyNot AvailableNot Availablecompleted
NCT00058695
Genetic Factors in Age-Related Macular DegenerationNo drug interventionsNot AvailableNot Availableterminated
NCT02555995
Assessment of Scan Quality of Sparse OCT Retina Scanner (MimoStudy01)No drug interventionsdiagnosticNot Availablecompleted
NCT00509795
Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD)treatment3completed
NCT01072214
A Safety Study to Evaluate Pazopanib Eye Drops in Healthy Volunteerstreatment1completed
NCT00527423
Randomized, Single-Masked, Long-Term, Safety and Tolerability Study of VEGF Trap-Eye in AMDNo drug interventionstreatment2completed
NCT00460408
Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular DegenerationNot AvailableNot Availablecompleted
NCT03714308
Aflibercept Injection Into the Vitreous Body of the Eye: Study to Learn More About Patient Relevant Outcomes, Real World Treatment Patterns and How Well the Treatment Works for Patients Suffering From Abnormal Growth of New Blood Vessels Under the Retina.Not AvailableNot Availablecompleted
NCT01006538
Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT)treatment4completed
NCT01670643
Reading Performance With a Video MagnifierNo drug interventionsNot AvailableNot Availablecompleted
NCT00343746
Novel Diagnostics With Optical Coherence Tomography: Retinal ImagingNo drug interventionsNot AvailableNot Availablerecruiting
NCT03215576
Clinical Study of Transplanting Human Retinal Pigment Epithelial Cells for Treatment of Macular DegenerationNo drug interventionstreatment1 / 2recruiting
NCT00001312
Age-Related Macular Degeneration and CataractNo drug interventionstreatmentNot Availablecompleted