Portal Hypertension (DBCOND0029015)

Identifiers

Synonyms
Hypertension Portal / Hypertension, Portal / Portal hypertensions / Portal hypertension / Portal hypertension (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Terlipressin
A drug used to treat bleeding caused by esophageal varices.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05161481
A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Livetreatment2terminated
NCT04668664
Endoscopic Ultrasound-Guided Portosystemic Pressure Gradient MeasurementsNo drug interventionsNot AvailableNot Availablecompleted
NCT06437964
Prophylactic Antibiotics in Endoscopic Secondary Prevention of Gastroesophageal Variceal BleedingNo drug interventionstreatmentNot Availablerecruiting
NCT06470386
The Efficacy and Safety of Alverine in the Treatment of Portal Hypertension in Patients With Liver Cirrhosistreatment2 / 3not_yet_recruiting
NCT06473493
The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertensiontreatment2 / 3not_yet_recruiting
NCT04720456
SHAPE of Portal Hypertension in Childrendiagnostic2recruiting
NCT04315571
Comparing Ascites Relief In Two Standard Treatments: Large Volume Paracentesis Vs. Early Tips Using Viatorr Controlled Expansion StentsNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT03138915
Radiomics Signature of Hepatic Venous Pressure Gradient (rHVPG) With CT Angiography (CHESS1701)No drug interventionsdiagnosticNot Availablecompleted
NCT04044248
TIPS Plus Transvenous Obliteration for Gastric VaricesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02842697
Virtual Hepatic Venous Pressure Gradient (vHVPG) With CT Angiography (CHESS1601)No drug interventionsdiagnosticNot Availablecompleted
NCT02504034
Interventional Radiology for the Treatment of Symptomatic Portal Hypertension in Patients With Cavernous Transformation of Portal VeinNo drug interventionstreatmentNot Availableunknown_status
NCT02767206
Evaluation of Gastroesophageal Varices by Transnasal Endoscopy.No drug interventionsNot AvailableNot Availableunknown_status
NCT05304455
Apixaban Prevents Portal Vein Thrombosis After Laparoscopic Splenectomy and Azygoportal DisconnectionpreventionNot Availablecompleted
NCT05282121
A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)treatment2terminated
NCT05041452
Multiparametric Cardio-hepatic MRI in Patients With Noncirrhotic Portal HypertensionNo drug interventionsNot AvailableNot Availableunknown_status
NCT03766880
MR-based Models for Clinically Significant Portal Hypertension in Cirrhosis (CHESS1802)No drug interventionsdiagnosticNot Availablecompleted
NCT03713606
Serum Biomarkers for Portal Hypertension in Cirrhosis (Pan-CHESS1802)No drug interventionsNot AvailableNot Availableunknown_status
NCT04645550
Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy(ESAWAAPT)prevention4completed
NCT03177499
Virtual Imaging-based Early Portal Pressure Gradient (vePPG) (CHESS1702)No drug interventionsdiagnosticNot Availablewithdrawn
NCT03470389
Establishment and Assessment of the HVPG Using Biofluid Mechanics (HVPGBFM)No drug interventionsdiagnosticNot Availableunknown_status
NCT03459378
Outcome After TIPSNo drug interventionsNot AvailableNot Availablecompleted
NCT02669875
Serelaxin To Lower Portal Pressuretreatment2completed
NCT02256046
Predictive Factors and Outcome of Esophageal Ulcers After Endoscopic Treatment of Esophageal VaricesNo drug interventionsscreeningNot Availableunknown_status
NCT02505152
Percutaneous Transhepatic Intrahepatic Portosystemic Shunt for Treatment of Portal Vein Occlusion With Symptomatic Portal Hypertension After SplenectomyNo drug interventionstreatmentNot Availableunknown_status
NCT02305914
Follow-up Study of Complications of Acute PancreatitisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01097811
Comparison Between Erythromycin and Neomycin Treatment of Hepatic EncephalopathytreatmentNot Availableunknown_status
NCT01095185
Efficacy of Statin Association With Standard Treatment in Prevention of Recurrent Hemorrhage in Patient With Cirrhosis and Variceal Bleedingtreatment3completed
NCT03175731
PPIs and Gastroesophageal Varices in Liver Cirrhosis (PPIs: Proton Pump Inhibitors)No drug interventionstreatment4completed
NCT03315767
Spleen-ARFI-assisted-Portal-Hypertension-Evaluation-Study (SAPHES)No drug interventionsdiagnosticNot Availableunknown_status
NCT02462967
Clinical Trial to Evaluation the Safety and Efficacy of GR-MD-02 for the Treatment of Liver Fibrosis and Resultant Portal Hypertension in Patients With Nash Cirrhosistreatment2completed
NCT00004641
A Study to Prevent Complications of High Blood Pressure Caused by Hepatitis in Patients With Cirrhosisprevention2completed
NCT06082843
A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the Bellytreatment2terminated
NCT05475015
3D-MRE for Assessing Cirrhosis and Portal HypertensionNo drug interventionsNot AvailableNot Availablerecruiting
NCT06099015
Cera™ Vascular Plug System Post-Market Clinical Follow-UpNo drug interventionsNot AvailableNot Availablerecruiting
NCT06173947
SSM Predicts Outcomes of CLD Inpatients With Acute Liver InjuryNo drug interventionsNot AvailableNot Availablerecruiting
NCT04807803
Evaluation of Minimal Hepatic Encephalopathy in Patients With Cirrhosis and Portal HypertensionNo drug interventionspreventionNot Availablerecruiting
NCT04975490
Characterization and Pathogenesis of ACLFNo drug interventionsNot AvailableNot Availablerecruiting
NCT01923064
Injection of Cyanoacrylate+Lipiodol vs Cyanoacrylate+Lauromacrogol in Gastric VaricestreatmentNot Availablecompleted
NCT00450164
Secondary Prophylaxis After Variceal Bleeding in Non-Respondersprevention4completed
NCT03427164
Ultrasound Elastography Assessment of Spleen and Liver Stiffness Before and After Transjugular Intrahepatic Portosystemic Shunt (TIPS) ProcedureNo drug interventionspreventionNot Availablecompleted
NCT01072721
Non Invasive Study of the Hepatic Fibrosis in Paediatrics by the Method of Study of Pediatric Hepatic FibrosisNo drug interventionsdiagnosticNot Availablecompleted
NCT05551884
Non-invasive Diagnosis of Portal Hypertension in Cirrhosis Based on Metabolomics TechnologyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05227833
Vonoprazan Efficacy to Prevent Post Variceal Band Ligation Ulcerprevention3completed
NCT01188733
Efficacy of Long-acting Octreotide (Sandostatin LAR) in Reducing Portal Pressure in Patients With Cirrhosisprevention1 / 2completed
NCT01897051
Rifaximin and Propranolol Combination Therapy Versus Propranolol Monotherapy in Cirrhotic Patientstreatment2 / 3unknown_status
NCT02922751
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)No drug interventionsNot AvailableNot Availablecompleted
NCT03277651
Noninvasive Diagnostic Platform for Liver Fibrosis and Portal HypertensionNo drug interventionsNot AvailableNot Availableunknown_status
NCT06054451
Clinical Diagnosis and Pathological Spectrum of Porto-sinusoidal Vascular Disease in IndiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT05765253
Achieving Portal Access With Scorpion Post-Approval Study (APASS)No drug interventionstreatmentNot Availableterminated
NCT06122753
Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein ThrombosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT01282398
Study About Simvastatin in Portal Hypertension in Compensated Cirrhosisprevention4unknown_status
NCT05502198
Relevance of Sarcopenia in Advanced Liver DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT00766805
Endoscopic Variceal Ligation (EVL)+ Drugs Versus Endoscopic Variceal Ligation (EVL) Alone For Secondary ProphylaxispreventionNot Availablecompleted
NCT04692805
EUS-guided PSE in Combination With EUS-guided Treatment of Varices for Patients With Portal HypertensionNo drug interventionstreatmentNot Availableunknown_status
NCT04576897
Velacur by Sonic Incytes for Portal HypertensionNo drug interventionsdiagnosticNot Availablecompleted
NCT02802228
Study to Assess Safety and Efficacy of Ifetroban for Treatment of Portal Hypertension in Cirrhotic Patientstreatment2completed
NCT04107428
Somatostatin in Living Donor Liver Transplantationtreatment4unknown_status
NCT02053571
Evaluation of 3D Overlay During Transjugular Intrahepatic Portosystemic Shunt (TIPS) ProcedureNo drug interventionstreatmentNot Availablecompleted
NCT06210178
Non-Invasive Portal and Hepatic Vein Pressure EstimationNo drug interventionsdiagnosticNot Availablerecruiting
NCT00331188
Use of Sanvar® With Endoscopic Treatment for the Control of Acute Variceal Bleedingtreatment3completed
NCT03628807
Non-invasive Evaluation Program for TIPS and Follow Up NetworkNo drug interventionsNot AvailableNot Availablecompleted
NCT04123509
Non-invasive Method for Predicting the Presence of Gastroesophageal Varices in Patients With CirrhosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01644656
Non-invasive Diagnosis of Portal Hypertension With Acoustic Radiation Force Impulse (ARFI)No drug interventionsdiagnosticNot Availablecompleted
NCT04633356
EUS Guided Portal-systemic Pressure Gradient MeasurementNo drug interventionsdiagnostic1 / 2recruiting
NCT01282385
Hemodynamic Effect of Simvastatin With Beta Blockers in Clinical Portal Hypertensionprevention4unknown_status
NCT02994485
Evaluation Of The Portal Pressure By Doppler Ultrasound In Cirrhotic Patients Before And After Simvastatintreatment4completed
NCT02635815
Risk Factors for Variceal Bleeding in Egyptian Patients With Non-Cirrhotic Portal HypertensionNo drug interventionsNot AvailableNot Availablecompleted
NCT06097715
Clinical,Endoscopic and Radiological Assessment of Portal Hypertension in Children With Chronic Liver DiseasesNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT05653115
Portal Hypetension and Bariatric Surgery (BARIAPORTAL)No drug interventionsNot AvailableNot Availablerecruiting
NCT06144437
Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of GOV in Patients With cACLDNo drug interventionsNot AvailableNot Availablerecruiting
NCT03932552
Effects of a Novel Physical Exercise Program in Patients With Cirrhosis (the LFN-exercise Protocol)No drug interventionstreatmentNot Availablecompleted
NCT03827200
A Study Evaluating the Utility of Ambrisentan in Lowering Portal Pressure in Patients With Liver Cirrhosistreatment2terminated
NCT06013670
Standard Therapy and TIPS for Moderate to High-risk Esophageal and Gastric Variceal BleedingNo drug interventionspreventionNot Availablerecruiting
NCT05357599
The Use of Endoscopic Ultrasound-Guided Portal Pressure Measurements to Guide Beta-Blocker Therapy in Patients With Compensated CirrhosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03451149
Feasibility And Safety Of Transjugular Intrahepatic Portosystemic Shunt (TIPS) Creation Using A Radiofrequency GuidewireNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT01842113
Quality of Life and Nutritional Improvements in Cirrhotic Patientstreatment4terminated
NCT00414713
Transfusion Requirements in Gastrointestinal (GI) BleedingNo drug interventionstreatment4unknown_status
NCT04421118
The Precise Selection of Stent Diameter for Portal Hypertension Patients With TIPSNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT02178319
Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled TrialNo drug interventionstreatmentNot Availableunknown_status
NCT04393519
Non-invasive Evaluation Program for TIPS and Follow Up Network 2 (NEPTUN2)No drug interventionsNot AvailableNot Availablerecruiting
NCT05789641
Multimodal Ultrasound and Portal HypertensionNo drug interventionsNot AvailableNot Availablerecruiting
NCT03195634
WFA+M2BP in Evaluation of Portal Hypertension and Clinical Outcome in Patients With Liver CirrhosisNot AvailableNot Availableunknown_status
NCT05928624
A Pilot Trial to Test the Feasibility of Utilizing Home Blood Pressure Monitoring to Optimize the Administration of Midodrine Among Decompensated Cirrhosis PatientsNo drug interventionsotherNot Availablerecruiting
NCT03438916
MRI to Assess the Effect of Non-selective Beta-blocker in Patients With CirrhosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03748563
Accuracy of Magnetically Maneuvered Capsule Endoscopy for Detection of EGV in Patients With CirrhosisNo drug interventionsdiagnosticNot Availablecompleted
NCT03409263
Austrian Registry on Transjugular Intrahepatic Portosystemic ShuntsNo drug interventionsNot AvailableNot Availablerecruiting
NCT06449339
Non-selective Beta-blocker in Compensated Advanced Chronic Liver Diseasetreatment4recruiting
NCT05027425
Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplanttreatment2recruiting
NCT03083925
Viatorr CX Case-control Study for Complications of Portal HypertensionNo drug interventionsNot AvailableNot Availablecompleted
NCT02778425
The Treatment of Hepatocirrhosis and Portal HypertensionNo drug interventionstreatmentNot Availablecompleted
NCT02692430
The International Imaging Registry in Liver Cirrhosis (BAVENO-VI SPSS GROUP).No drug interventionsNot AvailableNot Availableunknown_status
NCT06000748
NEPH-ROSIS (NEPHrology in CirRhOSIS) Pilot Trial: A Trial to Treat Acute Kidney Injury Among Hospitalized Cirrhosis PatientsNo drug interventionstreatment2 / 3recruiting
NCT05719857
Hepatic Venous Pressure Gradient and Elastography in Porto-sinusoidal Vascular DisorderNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT01687257
Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensationtreatment2completed
NCT02134626
Simvastatin Effect on Portal Hypertensiontreatment3completed
NCT03031366
A Novel Approach for Transjugular Intrahepatic Portocaval Shunt Creation Using Real-time Three Dimensional RoadmapNo drug interventionstreatmentNot Availablecompleted
NCT01551966
Esophageal Capsule Endoscopy in ChildrenNo drug interventionsdiagnosticNot Availablecompleted
NCT02945982
Treatment of Moderate and Severe Cirrhotic Portal Hypertension Due to HBV With Fuzheng Huayu and Entecavirtreatment4unknown_status
NCT03352882
Impact of Transjugular Intrahepatic Portosystemic Shunts on Liver StiffnessNo drug interventionsdiagnosticNot Availableterminated
NCT00163982
Vasoactive Peptides in Portal PressuretreatmentNot Availableunknown_status
NCT06432582
hepatomiR cACLD StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06549673
Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological FactorsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02046473
3D Sonographic Measurement of Volumetric Flow in Transjugular Intrahepatic Porto-Systemic ShuntsNo drug interventionshealth_services_researchNot Availablecompleted
NCT03171727
Low Molecular Weight Heparin for the Prevention of Early TIPS DysfunctiontreatmentNot Availableunknown_status
NCT00369694
Short Course Terlipressin for Control of Acute Variceal Bleedingtreatment4completed
NCT00737594
Efficacy and Safety of Cobiprostone in Patients With Portal Hypertensiontreatment2terminated
NCT00594191
Efficacy and Safety of Simvastatin in the Treatment of Portal Hypertensiontreatment2completed
NCT00493480
Danish Carvedilol Study in Portal Hypertensionprevention3completed
NCT04397289
Anticoagulation Therapy After Splenectomy in Cirrhosis Patientprevention1 / 2completed
NCT05052892
A Novel Spleen-dedicated Stiffness Measured by FibroScan to Evaluate Cirrhotic Portal Hypertension (CHESS2105)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02850692
Portal Hypertension and Systemic Endothelial FunctionNo drug interventionspreventionNot Availableunknown_status
NCT06122792
Preemptive TIPS for Gastric Variceal Bleeding in Patients With CirrhosisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05402644
Hepatectomy for Early-stage HCC Patients With CSPHNo drug interventionsNot AvailableNot Availablecompleted
NCT03720067
Propranolol, Carvedilol and Rosuvastatin in the Prevention of Variceal Bleeding in Cirrhotic Portal Hypertensiontreatment2 / 3unknown_status
NCT02439567
Transient Elastography to Assess Liver Fibrosis and Portal Hypertension in HCV Cirrhotic Patients Treated With New Antiviral Drugs (SPLEEN-C)No drug interventionsotherNot Availablecompleted
NCT04578301
Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT06265272
Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver CirrhosisNot AvailableNot Availablerecruiting
NCT02621372
Correlation of Platelets Count With Endoscopic Findings in a Cohort of Egyptian Patients With Liver CirrhosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03483272
MRI to Assess the Effect of Terlipressin in Patients With Acute Hepatorenal Syndrome (HRS-AKI)No drug interventionsNot AvailableNot Availablecompleted
NCT04525768
Gastroesophageal Varices in CavernomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05689268
EUS-PPG vs HVPG in Portal HypertensionNo drug interventionsdiagnosticNot Availablecompleted
NCT00591968
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican CommunityNo drug interventionshealth_services_researchNot Availablecompleted
NCT01267669
A Trial of Somatostatin With Endoscopic Variceal Ligation (EVL) in Control of Acute Variceal BleedingtreatmentNot Availablecompleted
NCT04828369
Efficacy and Safety of EUS-Guided Therapy Versus BRTO for Gastric Varices With ShuntNo drug interventionsNot AvailableNot Availablecompleted
NCT04191369
EGD vs EUS in Diagnosing Portal Hypertension in Cirrhotic Patients.No drug interventionsdiagnosticNot Availableunknown_status
NCT04010669
The Role of Somatostatin in the Hemodynamics of the Hepatic Circulation in Patients Undergoing Liver Resectionprevention3unknown_status
NCT04472312
Portal Pressure Effects of Phlebotomy Combined to Vasopressin Use in Cirrhotic Patients Undergoing Liver TransplantationNo drug interventionsNot AvailableNot Availablecompleted
NCT05402410
An AI Model Based on Smartphone-derived Multimodality Images to Evaluate Portal Hypertension in Patients With Cirrhosis (CHESS2203)No drug interventionsNot AvailableNot Availableunknown_status
NCT05794555
LiveSMART Trial to Prevent Falls in Patients With Cirrhosistreatment3recruiting
NCT05703750
Impact of Clinical Evident Portal Hypertension on HCC With TACE (CHANCE-CHESS 2301)No drug interventionsNot AvailableNot Availablerecruiting
NCT02356250
A Pilot Study: Defining Peripheral Endothelial Function in Portal Hypertensive Cirrhotic PatientsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT03532750
Splenic Embolization for Portal HypertensionNo drug interventionstreatmentNot Availablewithdrawn
NCT02508623
Effect of Administration of Rifaximin on the Portal Pressure of Patients With Liver Cirrhosis and Esophageal Varicestreatment3unknown_status
NCT02975323
Doppler Ultrasound Hepatic Vein Waveform as a Non-invasive Tool in the Assessment of Severity of Portal Hypertensiontreatment3unknown_status
NCT04863703
Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D)Not AvailableNot Availablerecruiting
NCT04073290
Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and Lactuloseprevention4unknown_status
NCT01598064
Probiotics for Liver Cirrhosis With Portal HypertensionNo drug interventionspreventionNot Availablecompleted
NCT00563602
Treatment for Prevention of Variceal Rebleeding Guided by the Hemodynamic ResponseNo drug interventionsprevention4unknown_status
NCT02477384
8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal RebleedingtreatmentNot Availablecompleted
NCT05508633
The Instant Efficacy and Safety of Alverine in Decreasing Portal Hypertension: an Exploratory Pilot Studytreatment2unknown_status
NCT04111133
Ivabradine in Cirrhotic CardiomyopathytreatmentNot Availablerecruiting
NCT02776553
A Physical Activity Program in End-state Liver DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT06434753
Zinc Supplementation to Improve Prognosis in Patients With Compensated Advanced Chronic Liver Disease.No drug interventionstreatment3recruiting
NCT00534677
The Safety & Efficacy of Terlipressin vs Octreotide for the Control of Variceal Bleedtreatment4completed
NCT06147947
Liver and Spleen Stiffness Measured by TE and 2D-SWE for Diagnosis of CSPH in Patients With cACLDNo drug interventionsNot AvailableNot Availablerecruiting
NCT01560845
ABMSC Infusion Through Hepatic Artery in Portal Hypertension Surgery for the Treatment of Liver CirrhosisNo drug interventionstreatment2 / 3unknown_status
NCT02489045
Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertensiondiagnostic4completed
NCT05749198
Portal Hypertension Using Magnetic Resonance ElastographyNo drug interventionsNot AvailableNot Availablecompleted
NCT00006398
Prevention of Esophageal Varices by Beta-Adrenergic Blockersprevention3completed
NCT05872698
Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.prevention4recruiting
NCT02508298
Surrogate Markers of Portal PressurediagnosticNot Availablecompleted
NCT03171805
The Use of Propranolol for the Prevention of Worsening of Esophageal Varices in Patients With Isolated Gastric VaricestreatmentNot Availableunknown_status
NCT05470205
Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewaldiagnostic3recruiting
NCT00587197
A Prospective Evaluation of Computerized Tomographic(CT) Scanning as a Screening Modality for Esophageal VaricesNo drug interventionsNot AvailableNot Availablecompleted
NCT02364297
TIPS in Fundal Variceal Bleeding (the TFB Study)No drug interventionstreatmentNot Availableunknown_status
NCT02230683
A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertensiontreatment2completed
NCT05515861
Evaluation of EUS in Preventing Rebleeding After Endoscopic Cyanoacrylate Injection for Gastric VaricesNo drug interventionspreventionNot Availableunknown_status
NCT05107271
Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02929407
A Study to Investigate the Safety and Effect of the Study Drug (FE 204205) in Patients With Cirrhotic Portal HypertensionNo drug interventionstreatment1terminated
NCT02945956
Treatment of Low-grade Cirrhotic Portal Hypertension Due to Hepatitis B Virus With Fuzheng Huayu and Entecavirtreatment4unknown_status
NCT05782556
Freiburg TIPS RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03267615
VICIS - Vienna Cirrhosis StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT03072615
Role of SWE-change After TIPS in the Prediction of Prognosis After TIPSNo drug interventionsNot AvailableNot Availablecompleted
NCT00831337
Evaluation of Probiotics in the Treatment of Portal HypertensionNo drug interventionspreventionNot Availablecompleted
NCT05325437
The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on Liver Reserve Function for Cirrhosis PatientsNo drug interventionstreatmentNot Availablerecruiting
NCT01851252
MBT Versus HVPG in Identifying Responders to Portal Hypertension TherapyNo drug interventionssupportive_care1completed
NCT04932200
The Timing of Emergency Endoscopy for Esophagogastric Variceal Bleeding in CirrhosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01756859
MRI in Portal HypertensionNo drug interventionsNot AvailableNot Availableunknown_status
NCT02925975
Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPSprevention4unknown_status
NCT04957875
Timing of Endoscopy for Acute Variceal Bleeding in Patients With CirrhosisNo drug interventionsNot AvailableNot Availablecompleted
NCT05021406
Extension Study of Carvedilol RCT StudypreventionNot Availablerecruiting
NCT02907749
Spironolactone on Fibrosis Progrssion-Portal Hypertension(FP-PH)in Cirrhosisprevention4completed
NCT00787436
Secondary Prophylaxis of Gastrointestinal Bleeding in Cirrhotic Patients Using THALIDOMIDEprevention3withdrawn
NCT03114813
Can MRI Evaluate Beta-blocker Response in Portal Hypertension?Not AvailableNot Availableunknown_status
NCT02344719
Effect of Taurine on Portal Hemodynamics in Patients With Advanced Liver Cirrhosistreatment4completed
NCT01032941
The Effect of Probiotics (VSL) on Portal Hypertensionhealth_services_research1 / 2completed
NCT01070641
RCT of Carvedilol Versus Variceal Band Ligation in the Primary Prophylaxis of Oesophageal Variceal Haemorrhageprevention4unknown_status
NCT01774617
Comparative Analysis of Different Tests to Evaluate Prognosis of Patients on Liver Transplant Waiting ListNo drug interventionsNot AvailableNot Availablecompleted
NCT03094234
8mm-TIPS Versus Endoscopic Variceal Ligation (EVL) Plus Propranolol for Prevention of Variceal Rebleeding in Patients With Child A CirrhosistreatmentNot Availableunknown_status
NCT03443934
Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive AssessmentNo drug interventionsNot AvailableNot Availablecompleted
NCT06576934
Early TIPS in Patients With Liver Cirrhosis and AscitesNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT04640116
TIPS Combined With Microwave Ablation in HCC Patients With Refractory AscitesNo drug interventionstreatmentNot Availableunknown_status
NCT00004796
Phase II Study of Lactulose and Circadian Rhythms in Patients With Cirrhosistreatment2completed
NCT06117735
Clinical Study of PTFE Covered Stent for Treating Portal HypertensionNo drug interventionstreatmentNot Availablerecruiting
NCT01456286
Randomized Controlled Trial to Assess the Effects of Sapropterin on Hepatic and Systemic Hemodynamics in Patients With Liver Cirrhosis and Portal Hypertensiontreatment2 / 3completed
NCT01236339
Early TIPS for Ascites StudyNo drug interventionstreatmentNot Availableterminated
NCT00570622
Effect of Pioglitazone on Portal and Systemic Hemodynamics in Patients With Advanced Cirrhosistreatment4completed
NCT03825848
The Influence of Post-transjugular Intrahepatic Portosystemic Shunt Hepatic EncephalopathyNo drug interventionstreatmentNot Availableunknown_status
NCT04724148
Impact of Fentanyl Analgesia on the Accuracy of HVPG Measurements in Patients With Portal HypertensiontreatmentNot Availablerecruiting
NCT04994548
Endoscopic Resection of Early Esophageal Tumors in the Context of Cirrhosis or Portal HypertensionNo drug interventionsNot AvailableNot Availablecompleted
NCT01931826
Treatment Schistosomal Portal Hypertension: Efficacy of Endoscopy or SurgeryNo drug interventionspreventionNot Availablecompleted
NCT02480426
3D CT Guidance for Transjugular Intrahepatic Portosystemic Shunt CreationNo drug interventionstreatmentNot Availableunknown_status
NCT04820166
The Effect of Monitoring PVP on Clinical Outcomes in Patients With PHNo drug interventionsNot AvailableNot Availablerecruiting
NCT01408966
Effects of Dark vs. White Chocolate on the Postprandial Increase in Portal Pressure in CirrhosisNo drug interventionstreatment2completed
NCT03783065
HVPG-guided Laparoscopic Versus Endoscopic Therapy for Variceal Rebleeding in Portal Hypertension: A Multicenter Randomized Controlled Trial (CHESS1803)preventionNot Availableunknown_status
NCT03736265
Carvedilol for Prevention of Esophageal Varices ProgressionpreventionNot Availableunknown_status
NCT04121520
Perioperative Care of HVPG Measurement (CHESS1904): An International Multicenter SurveyNo drug interventionsNot AvailableNot Availablecompleted
NCT03155282
Utility of EUS-elastography to Predict Portal HypertensionNo drug interventionsNot AvailableNot Availablecompleted
NCT04786782
The vPPG-detecting Software Guided Management of Cirrhotic Portal HypertensionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00163631
Relationship of Vasoactive Peptide Levels to Portal Pressure and Patient Outcomes in Patients With Hepatic CirrhosisNo drug interventionsNot AvailableNot Availablecompleted
NCT03130127
Continuous Versus Bolus Infusion of Terlipressin for Portal Hypertension Related Bleeding in Liver CirrhosistreatmentNot Availablenot_yet_recruiting
NCT06266260
Evaluation of the Performance of Direct Portal Pressure Measurement by Endoscopic Ultrasound in a Large Cohort of Patients With Advanced Chronic Liver Disease of Different Etiologies and Newly Diagnosed Clinically Significant Portal Hypertension (EVADIPP)No drug interventionsNot AvailableNot Availablerecruiting
NCT05050994
Ultrasound Guided Microwave Ablation of Splenomegaly in ChildrenNo drug interventionstreatmentNot Availablerecruiting
NCT05483894
Atorvastatin Use and Portal Hypertension in Patients With Hepatitis B Virus-related Liver Cirrhosis: A Randomized Controlled Trialtreatment2not_yet_recruiting
NCT01751191
HVPG for Rebleeding Risk StratificationNo drug interventionsNot AvailableNot Availablecompleted
NCT01410591
TIPS With 8- OR 10-mm Covered Stent for Preventing Variceal RebleedingNo drug interventionstreatmentNot Availablecompleted
NCT01131962
Comparing Two Methods to Stop Vomiting of Blood Using the EndoscopeNo drug interventionstreatment3completed
NCT05047029
Myocardial Fibrosis and Inflammation in Liver CirrhosisNo drug interventionsNot AvailableNot Availablecompleted
NCT01440829
The Effectiveness of L-ornithine-L-aspartate (LOLA) on Plasma Ammonia in Cirrhotic Patients After TIPStreatment2 / 3completed
NCT05767229
Acute Hemodynamic Response to Carvedilol in Children With Clinically Significant Portal Hypertension.treatmentNot Availablerecruiting
NCT03439189
Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14diagnosticNot Availablecompleted
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Carvedilol vs. Propranolol in Second Prophylaxis of Variceal BleedingpreventionNot Availablenot_yet_recruiting
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A Novel Imaging Based Quantitative Model-aided Detection of Portal Hypertension in Patients With Cirrhosis (CHESS2104)No drug interventionsNot AvailableNot Availablenot_yet_recruiting
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Two-dimensional Shear Wave Elastography for Assessment of Cirrhosis and Portal HypertensionNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
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CT-based HVPG Assessment for Predicting the Prognosis of HCC With TACE (CHANCE-CHESS 2302)No drug interventionsNot AvailableNot Availablerecruiting
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Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertensiontreatment2completed
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Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosistreatment4unknown_status
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A Combined Model Based on Spleen Stiffness, Liver Stiffness and Platelets for Assessing Portal Hypertension in Compensated Cirrhosis (CHESS2202)No drug interventionsNot AvailableNot Availablerecruiting
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Noninvasive Prediction of Portal Hypertension in Cirrhosis Using Sound Touch ViscoelastographyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
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Efficacy and Safety of Intraparenchymal Portal Vein Covered Stents in Treating Portal Hypertension and Its ComplicationsNo drug interventionstreatmentNot Availablenot_yet_recruiting
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Microparticles in Cirrhosis and Portal HypertensionNo drug interventionsbasic_scienceNot Availablecompleted
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Assessing Outcome After H-graft Shunt PlacementNo drug interventionsNot AvailableNot Availablecompleted
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Effect of Antiviral Therapy on HVPG in Patients With Viral CirrhosisNo drug interventionsNot AvailableNot Availableunknown_status
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Assessment of Portal Hypertension With Multiparametric MRINo drug interventionsNot AvailableNot Availablecompleted
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Endoscopic Ruler for the Assessment of Variceal Bleeding Risks (CHESS2005)No drug interventionsNot AvailableNot Availablerecruiting
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Value of Von Willebrand Factor in Portal HypertensionNo drug interventionsNot AvailableNot Availableunknown_status
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EUS vs TJ for Liver Biopsy and Portal Pressure Gradient MeasurementNo drug interventionsdiagnosticNot Availableunknown_status
NCT04806750
Emricasan, an Oral Caspase Inhibitor, in Subjects With Non-Alcoholic Steatohepatitis (NASH) Cirrhosis and Severe Portal Hypertensiontreatment2completed