Chronic Rhinitis (DBCOND0038654)

Identifiers

Synonyms

Chronic rhinitis / Chronic hypertrophic rhinitis (disorder) / Chronic ulcerative rhinitis (disorder) / Ozena / Ozena (disorder) / Chronic rhinitis (disorder) / Rhinitis NOS / Rhinitis / Rhinitis (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Acetylcysteine	A medication that can be used as a mucolytic in patients with certain lung conditions and as an antidote for acetaminophen overdose.	Solute carrier organic anion transporter family member 1B1transporter NAPQI (N-acetyl-p-benzoquinone imine)target Solute carrier family 22 member 6transporter Aminoacylase-1target Inhibitor of nuclear factor kappa-B kinase subunit alphatarget Inhibitor of nuclear factor kappa-B kinase subunit betatarget Glutathione synthetasetarget Cystine/glutamate transportertarget Glutamate receptor ionotropic, NMDA 2Btarget Glutamate receptor ionotropic, NMDA 1target Glutamate receptor ionotropic, NMDA 2Atarget Glutamate receptor ionotropic, NMDA 2Dtarget Glutamate receptor ionotropic, NMDA 3Atarget Albumincarrier Aminoacylase-1enzyme
Amidephrine	A sympathomimetic indicated in the treatment of acute, chronic, vasomotor, and allergic rhinitis.	Alpha-2C adrenergic receptortarget
Dimetindene	A 1st generation selective H1 antagonist used topically as an antipruritic and orally to treat allergies.	Muscarinic acetylcholine receptor M2target Histamine H1 receptortarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06599736	A Study of RhinAer Stylus for Treating Chronic Rhinitis	No drug interventions	treatment	Not Available	not_yet_recruiting
NCT05626621	Efficacy of Azelastine and Mometasone Irrigation in Comparison to Nasal Sprays in Patients With Chronic Rhinitis	Azelastine Mometasone Mometasone furoate	treatment	4	recruiting
NCT00737906	Surgical Reduction of the Inferior Turbinates for Nasal Obstruction	No drug interventions	treatment	4	terminated
NCT04614324	A Study of RhinAer ARC Stylus for Treating Chronic Rhinitis (RELIEF)	No drug interventions	treatment	Not Available	active_not_recruiting
NCT04769596	Safety and Efficacy Study of the Neurent Medical NEUROMARK™ System in Subjects With Chronic Rhinitis	No drug interventions	treatment	Not Available	completed
NCT03181594	Evaluation of the ClariFix™ Cryotherapy Device in Subjects With Chronic Rhinitis	No drug interventions	treatment	Not Available	completed
NCT05591989	Clinical Evaluation of Safety and Efficacy for the NEUROMARK System in Subjects With Chronic Rhinitis (PARAGON)	No drug interventions	treatment	Not Available	active_not_recruiting
NCT01364467	The Effect of Oral Guaifenesin on Pediatric Chronic Rhinitis: A Pilot Study	Guaifenesin	treatment	2	completed
NCT06370468	The Epidemiological and Intrinsic Characteristics of Chronic Rhinitis	No drug interventions	Not Available	Not Available	recruiting
NCT04533438	RhinAer Procedure for Treatment of Chronic Rhinitis Study	No drug interventions	treatment	Not Available	active_not_recruiting
NCT03727347	Posterior Nasal Nerve (PNN) Rhinitis Study	No drug interventions	treatment	Not Available	completed
NCT04154605	ClariFix Rhinitis RCT	No drug interventions	treatment	Not Available	unknown_status
NCT05324397	Safety and Efficacy Study of the Neurent Medical NEUROMARK™ System in Subjects With Chronic Rhinitis (CLARITY)	No drug interventions	treatment	Not Available	completed
NCT04375293	Characterisation of the Nasal Microbiome in Patients With N-ERD	No drug interventions	basic_science	Not Available	completed
NCT06128200	NEUROMARK Randomized Controlled Trial	No drug interventions	treatment	Not Available	recruiting
NCT04684875	Quality of Life Impact of Chronic Rhinitis Treatment With Aerin Medical Device	No drug interventions	Not Available	Not Available	completed
NCT03739216	Registry of Subject Treated With ClariFix	No drug interventions	Not Available	Not Available	completed
NCT05331222	Proof-of-Concept Interventional Study With a Nasal Spray of JT-1 in Patients With Chronic Rhinitis or Chronic Sinusitis	No drug interventions	treatment	Not Available	terminated
NCT05648565	Effects of Radiofrequency Ablation of Posterior Nasal Nerves on Inflammatory Cytokines, Peak Nasal Inspiratory Flow, and Nasal Blood Flow in Patients With Chronic Rhinitis	No drug interventions	treatment	Not Available	completed
NCT03893227	Prevalence of Nasal Hyperreactivity in Chronic Upper Airway Inflammation	No drug interventions	Not Available	Not Available	completed
NCT00584662	Oxymetazoline Hydrochloride in Combination With Nasal Glucocorticosteroid for Perennial Allergic and Non-allergic Rhinitis in Subjects With Persistent Nasal Congestion	Oxymetazoline	treatment	Not Available	terminated
NCT01546662	A Randomized Double Dummy Double Blind Dose Determining Place-bo Controlled Study to Evaluate Efficacy of Investigational Product E-RH-06 at 2 Dose Levels for the Metabolic Management of Chronic or Recurrent, Non-infective Nasal Congestion With-or-without Rhinorrhea.	No drug interventions	supportive_care	Not Available	unknown_status
NCT03791489	Multi-Treatment PNN Modulation for Chronic Rhinitis	No drug interventions	treatment	Not Available	completed
NCT05937308	NEUROMARK Registry Study	No drug interventions	treatment	Not Available	recruiting