Lichen Planopilaris (DBCOND0040669)

Identifiers

Synonyms

Lichen Plano-Pilaris / Lichen planopilaris / Lichen planopilaris (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Salicylic acid	An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.	Albumincarrier Prostaglandin G/H synthase 1target Prostaglandin G/H synthase 2target Aldo-keto reductase family 1 member C1target Solute carrier family 22 member 6transporter Solute carrier family 22 member 10transporter Organic anion transporter 3transporter Solute carrier family 22 member 11transporter Solute carrier organic anion transporter family member 2B1transporter Monocarboxylate transporter 1transporter Solute carrier family 22 member 7transporter Cytochrome P450 2C9enzyme Carbonic anhydrase 6target Carbonic anhydrase 12target Carbonic anhydrase 2target Carbonic anhydrase 4target Carbonic anhydrase 1target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03630198	Pain Outcomes Following Intralesional Corticosteroid Injections	Lidocaine	treatment	4	completed
NCT06512766	a Retrospective Study on the Systemic Treatment of LPP and FFA	Cyclosporine Hydroxychloroquine Methotrexate	Not Available	Not Available	completed
NCT03082560	Design and Validation of a New Assessment Tool for Lichen Planopilaris	No drug interventions	Not Available	Not Available	unknown_status
NCT05030415	Ixekizumab in Adult Patients With Lichen Planus and Lichen Planopilaris	Ixekizumab	treatment	0	completed
NCT03346668	Role of Neurogenic Inflammation and Topical 6% Gabapentin Therapy in Symptomatic Scarring Alopecia	Gabapentin	treatment	0	completed
NCT06512753	The Effectiveness of Hydroxychloroquine Versus Methotrexate in the Treatment of Lichen Planopilaris in Routine Clinical Care: a Patient Preference Trial	Hydroxychloroquine Methotrexate	Not Available	Not Available	recruiting
NCT06091956	A Study of Deucravacitinib to Treat LPP and FFA	Deucravacitinib	treatment	2	active_not_recruiting
NCT03417141	Valchlor in the Treatment of Lichen Planopilaris	Mechlorethamine	treatment	2	completed
NCT04409041	Oral Low-Dose Naltrexone for Lichen Planopilaris and Frontal Fibrosing Alopecia	Naltrexone	treatment	2	completed
NCT06202560	Effectiveness and Safety of Tofacitinib in Patients With Recalcitrant Frontal Fibrosing Alopecia : A Pilot Study	Tofacitinib	treatment	Not Available	enrolling_by_invitation
NCT00691769	Expression of Fas Protein in Skin Biopsies of Participants With Scarring Alopecia	No drug interventions	Not Available	Not Available	completed