Myeloid Leukemias (DBCOND0042450)

Identifiers

Synonyms
Leukemia, Myeloid / Myeloid leukaemia / Myeloid Leukemia / Myeloid leukemia, unspecified, not having achieved remission / Myeloid leukemia, unspecified / Myeloid leukemia (morphologic abnormality) / Myeloid leukemia (disorder) / Leukemia myeloid / Non-lymphoblastic leukaemia NOS / Non-lymphoblastic leukemia NOS / Unspecified myeloid leukaemia / Unspecified myeloid leukemia / Leukaemia myelogenous / Leukemia myelogenous / Myelocytic leukaemia / Myelocytic leukemia / Leukemia granulocytic NOS / Leukaemia granulocytic NOS / Leukaemia granulocytic / Leukemia granulocytic / Leukaemia myeloid / Myeloid leukemia NOS / Myeloid leukaemia NOS

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06369662
CD155 Expression in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT06643962
Venetoclax Combined With Intensive Therapy for Acute Myeloid Leukemia Patients With Lower Early Peripheral Blast Clearance Rate After Standard Induction TherapyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05282459
Enasidenib in MDS &Non-proliferative Chronic Myelomonocytic Leukemia w/o IDH2 Mutationsupportive_care1 / 2active_not_recruiting
NCT06537726
Breath Analysis for the Detection of Invasive Fungal InfectionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00339664
Analyses of Human Samples Collected in Clinical TrialsNo drug interventionsNot AvailableNot Availablecompleted
NCT02916979
Myeloid-Derived Suppressor Cells and Checkpoint Immune Regulators' Expression in Allogeneic SCT Using FluBuATGtreatment1completed
NCT00611247
Phase 2 Study of Temozolomide to Treat Poor Risk / Refractory Acute Myeloid Leukemiatreatment2completed
NCT05805605
Allo HSCT Using RIC and PTCy for Hematological Diseasestreatment2recruiting
NCT00451997
Gleevec/Low-Dose Ara-C Study for Elderly Patients With AML and Myelodysplastic Syndromestreatment2completed
NCT00512083
Phase II Study of AS1411 Combined With Cytarabine to Treat Acute Myeloid Leukemiatreatment2completed
NCT02370888
Lenalidomide After Allo-Hematopoietic Cell Transplant (HCT) in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndromes (MDS) Subjects With Minimal Residual Diseasetreatment1terminated
NCT04406207
Endogenous Retroviruses in Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06152809
CIML NK Cells With Venetoclax for AMLtreatment1active_not_recruiting
NCT04039100
Family Caregiver Ambassador Support for Family Caregivers of Patients With Hematological DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT01050036
Autologous Hematopoietic Cell Transplantation for Core-binding Factor Acute Myeloid LeukemiaNo drug interventionstreatmentNot Availableunknown_status
NCT05458258
Studying Malnutrition And Sarcopenia In Older Adults With Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablerecruiting
NCT04748848
A Safety, Tolerability and Preliminary Efficacy Study of CC-90011 in Combination With Venetoclax and Azacitidine in R/R Acute Myeloid Leukemia and Treatment-naïve Participants Not Eligible for Intensive Therapytreatment1terminated
NCT02538965
A Study of Lenalidomide in Pediatric Subjects With Relapsed or Refractory Acute Myeloid Leukemiatreatment2completed
NCT00025662
Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDSNo drug interventionstreatment2completed
NCT04598789
A Multicentre, Retrospective Study to Evaluate the Outcome of HSCT Mismatch Unrelated DonorsNo drug interventionsNot AvailableNot Availablecompleted
NCT01392989
Post T-plant Infusion of Allogeneic Cytokine Induced Killer (CIK) Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative Disorderstreatment2completed
NCT04310592
Natural Killer Cell (CYNK-001) Infusions in Adults With AMLtreatment1recruiting
NCT02333838
Reduced Toxicity Conditioning Prior to Unrelated Cord Cell Transplantation for High Risk Myeloid Malignanciesother2unknown_status
NCT00065143
Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrometreatment2completed
NCT06138587
Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantationtreatment1recruiting
NCT00568633
Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AMLtreatment3terminated
NCT01144793
Biomarker To Evaluate Protein Profiles of Neutropenic Fever/Infection With Acute or Chronic LeukemiasNo drug interventionsNot AvailableNot Availablecompleted
NCT06001788
Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemiatreatment1recruiting
NCT00233909
A Trial of Gemtuzumab Ozogamicin (GO) in Combination With Zosuquidar in Patients With CD33 Positive Acute Myeloid Leukemiatreatment1 / 2completed
NCT00306332
T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell TransplantationNo drug interventionstreatment3terminated
NCT01602952
Philadelphia Chromosome Positive CML Patients Without Optimal Response or Tolerance to Bcr-Abl TKItreatment1 / 2completed
NCT02577406
An Efficacy and Safety Study of AG-221 (CC-90007) Versus Conventional Care Regimens in Older Subjects With Late Stage Acute Myeloid Leukemia Harboring an Isocitrate Dehydrogenase 2 Mutationtreatment3completed
NCT06501196
A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic SyndromeNo drug interventionstreatment1recruiting
NCT03600558
Efficacy of FLAG Regimen for the Treatment of Patients With AMLNo drug interventionsNot AvailableNot Availableunknown_status
NCT04265963
CD123-Targeted CAR-T Cell Therapy for Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT00030186
Open Study of CEP-701 in Patients With Refractory Acute Myeloid Leukemia With FLT-3 Mutationtreatment2completed
NCT03080922
High Dose Donor Hematopoietic Stem Cell Infusion for Relapsed/Refractory AMLNo drug interventionstreatment1 / 2unknown_status
NCT04272125
Safety and Efficacy of CD123-Targeted CAR-T Therapy for Relapsed/Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1 / 2recruiting
NCT03066648
Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDStreatment1completed
NCT03417427
A Clinical Trail of Demethylation Drug Combined With Chemotherapy in Intermediate-risk AMLtreatment2recruiting
NCT01511289
Radotinib Versus Imatinib in Newly Diagnosed Philadelphia Chromosome and Chronic Myeloid Leukemia Chronic Phase Patientstreatment3completed
NCT05143840
Asciminib as Initial Therapy for Patients With Chronic Myeloid Leukemia in Chronic Phasetreatment2recruiting
NCT00129168
Zosuquidar in Combination With Daunorubicin and Cytarabine in Patients Ages 55-75 With Newly Diagnosed Acute Myeloid Leukemia (AML)treatment1 / 2completed
NCT06512610
ELN 2022 in MENAFC ( Middle Eastern or North Coast of Africa ) Patients With Newly AMLNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04789655
Study of CC-96191 in Participants With Relapsed or Refractory Acute Myeloid LeukemiaNo drug interventionstreatment1recruiting
NCT05194397
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT SurvivorsNo drug interventionstreatment2recruiting
NCT01643603
Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignanciestreatment1terminated
NCT00422890
Treatment of Imminent Haematological Relapse in Patients With AML and MDS Following Allogeneic Stem Cell Transplantation With 5-azacitidine (Vidaza®)No drug interventionstreatment3completed
NCT03659084
Study of the Outcome of Patients With Acute Myeloblastic Leukemia and Myelodysplastic Syndrome Receiving Iron Chelation Therapy After Allogeneic Hematopoietic Stem Cell TransplantationNot AvailableNot Availableunknown_status
NCT06130579
Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCTNo drug interventionstreatment2recruiting
NCT05031897
Reduced-Intensity Conditioning for the Prevention of Treatment-Related Mortality in Patients Who Undergo a Hematopoietic Stem Cell Transplanttreatment2recruiting
NCT00126893
Study to Determine the Optimal Biologic Dose of CC-401 in Subjects With High-Risk Myeloid Leukemiatreatment1terminated
NCT05363488
Retrospective Observational Research Study to Describe the Real World Use of Bosutinib in a Single Centre in ScotlandNot AvailableNot Availablecompleted
NCT02763475
NK Cells as Consolidation Therapy of Acute Myeloid Leukemia in Children/Adolescentstreatment2completed
NCT03638206
Autologous CAR-T/TCR-T Cell Immunotherapy for MalignanciesNo drug interventionstreatment1 / 2unknown_status
NCT05309018
Implantation of an Advanced Practice Nurse in the Complex Care Pathway of Patients With AMLNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04260022
Study of HQP1351 in Subjects With Refractory CML and Ph+ ALLtreatment1recruiting
NCT00001748
HLA-Mismatched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematological MalignanciesNo drug interventionstreatment1completed
NCT00887926
Study of IMC-EB10 in Participant With LeukemiaNo drug interventionstreatment1terminated
NCT06235801
A Phase I/II Study of Gilteritinib and Momelotinib for Patients With Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemiatreatment1 / 2recruiting
NCT00967343
Efficacy and Safety of a Donor Lymphocyte Preparation Depleted of Functional Host Alloreactive T-cells (ATIR) in Patients Undergoing a Peripheral Blood Stem Cell Transplant From a Related, Haploidentical DonorNo drug interventionsprevention2 / 3terminated
NCT00521664
A Trial Comparing a Prophylactic With a Therapeutic Platelet Transfusion Strategy in Two GroupsNo drug interventionstreatment3completed
NCT00114764
Trial Comparing Pegfilgrastim With Filgrastim as an Adjunct to Chemotherapy for Acute Myeloid Leukaemia (AML)treatment2completed
NCT02719821
Refining a Biobehavioral Intervention to Enhance Recovery Following Hematopoietic Stem Cell TransplantationNo drug interventionssupportive_careNot Availablecompleted
NCT05787951
Frequency and Risk Factors of Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00111345
Therapy-Optimization Trial for the Treatment of Acute Myeloid Leukemias (AML) in Children and Adolescentstreatment2 / 3unknown_status
NCT01380756
Study Evaluating Orally Administered AMG 900 in Adult Subjects With Acute Myeloid LeukemiaNo drug interventionstreatment1completed
NCT00001637
Immunosuppressive Preparation Followed by Blood Cell Transplant for the Treatment of Blood Cancers in Older AdultsNo drug interventionstreatment2completed
NCT05035706
Anti-Leukemia Immune Responses After Irradiation of Extramedullary TumorsNo drug interventionstreatment0recruiting
NCT06429449
Mitoxantrone for Venetoclax Resistant Acute Myeloid Leukemiatreatment1recruiting
NCT01066286
Genome Wide SNP Array-based Approach to Detect Micro-cytogenetic Lesions and KIT Mutation to Improve Treatment Outcomes in Patients With Core-binding Factor Positive Acute Myeloid LeukemiaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01779882
Cyclophosphamide and Busulfan as Conditioning Regimen Before Allogeneic HSCTtreatmentNot Availablecompleted
NCT03613727
Therapeutic Use of Intravenous Vitamin C in Allogeneic Stem Cell Transplant Recipientstreatment2completed
NCT00497991
Safety, Tolerability, PK and Efficacy of AZD1152 in Patients With Relapsed Acute Myeloid Leukemiatreatment1completed
NCT02489929
Evaluation of Cytidine Deaminase for Patient Suffering of a Myelodysplastic Syndrom or an AML Treated by AzacytidinediagnosticNot Availableunknown_status
NCT00543972
Dose Escalation Safety and Pharmacokinetic Study of AVE9633 as Single Agent in Relapsed/Refractory CD33-Positive Acute Myeloid Leukemiatreatment1terminated
NCT04714372
FT538 in Combination With Daratumumab in AML Acute Myeloid Leukemiatreatment1active_not_recruiting
NCT01760655
Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignanciestreatment2completed
NCT05871008
Integrated Actionable Aging Assessment for Cancer Patients PilotNo drug interventionshealth_services_researchNot Availablerecruiting
NCT04628338
IFN-γ to Treat Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) That Has Relapsed After Allogeneic Hematopoietic Stem Cell Transplantationtreatment0completed
NCT01066338
Genome-wide Pharmacogenetic Candidate Gene Single Nucleotide Polymorphism (SNP) Array-based Approach to Predict Chemoresponse and Survival in Patients With Acute Myeloid Leukemia With Normal KaryotypeNo drug interventionsNot AvailableNot Availableunknown_status
NCT02955043
Biobehavioral Intervention to Enhance Hematopoietic Stem Cell Transplant RecoveryNo drug interventionssupportive_careNot Availablecompleted
NCT00780104
Sirolimus in Combination With MEC in High Risk Myeloid Leukemiastreatment1completed