Bone Infection (DBCOND0045557)

Identifiers

Synonyms

Bone infection / Osteomyelitis, unspecified / Unspecified infection of bone, site unspecified / Unspecified infection of bone / Bone infection NOS / Infection of bone (disorder) / Osteomyelitis / Unspecified osteomyelitis / Unspecified osteomyelitis, site unspecified / Osteomyelitis (disorder) / Osteomyelitis NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Cephalexin	A first generation cephalosporin used to treat certain susceptible bacterial infections.	Albumincarrier Organic cation/carnitine transporter 2transporter Solute carrier family 15 member 1transporter Solute carrier family 15 member 2transporter Solute carrier family 22 member 6transporter Organic anion transporter 3transporter Multidrug and toxin extrusion protein 1transporter Penicillin-binding protein 3target Penicillin-binding protein 2atarget Penicillin-binding protein 1btarget Penicillin-binding protein 1Atarget Penicillin-binding protein 2Btarget
Tobramycin	An aminoglycoside antibiotic used to treat cystic fibrosis-associated bacterial, lower respiratory tract, urinary tract, eye, skin, bone, and skin structure infections.	16S ribosomal RNAtarget Bacterial outer membranetarget Cytoplasmic membranetarget 23S ribosomal RNAtarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04538053	BonE and Joint Infections - Simplifying Treatment in Children Trial	Cefazolin Cephalexin Flucloxacillin	treatment	4	recruiting
NCT05895903	Alveolar Ridges Expansion Using Osseodensification Versus Screw Expansion Technique	No drug interventions	treatment	Not Available	completed
NCT02335905	Ceftaroline for Treatment of Hematogenously Acquired Staphylococcus Aureus Osteomyelitis in Children	Ceftaroline fosamil	treatment	1 / 2	completed
NCT03550911	Biological Collection From Samples From The Gut Microbiota In Patients Having A Bone Or Joint Infection Treated By A Suppressive Subcutaneous Antibiotherapy With Betalactamine (CARBAMICROBIOTA)	No drug interventions	Not Available	Not Available	recruiting
NCT01677000	Clinical Priority Program-Bone Infection Registry	No drug interventions	Not Available	Not Available	completed
NCT04945434	Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis	No drug interventions	treatment	Not Available	unknown_status
NCT04440631	Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related Infection	No drug interventions	Not Available	Not Available	completed
NCT03403608	Subcutaneous Suppressive Antibiotic Therapy for Bone and Joint Infections	No drug interventions	Not Available	Not Available	completed
NCT03945864	Antimicrobial Synthetic Bone Grafts	No drug interventions	treatment	1 / 2	completed
NCT03134521	Population Pharmacokinetic Analysis of Daptomycin in Patients With Osteoarticular Infections	No drug interventions	Not Available	Not Available	unknown_status
NCT04154202	The Role of NM/CT 870 DR Camera in the Diagnosis of Joint Prosthesis and Tibial Open Reduction and Internal Fixation (ORIF) Complications.	No drug interventions	diagnostic	Not Available	unknown_status
NCT06132347	Performances of DendrisCHIP®OA in Bone and Joint Infections	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT03426761	Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections	Cefazolin Dalbavancin Daptomycin Nafcillin Vancomycin	treatment	4	completed
NCT05927311	Side Effects of Antibiotics in Bone and Joint Infections	No drug interventions	Not Available	Not Available	recruiting
NCT00974493	Oral Versus Intravenous Antibiotics for Bone and Joint Infections (OVIVA B&J)	No drug interventions	treatment	4	completed
NCT05753215	Controlled Trial of Omadacycline Randomized Treatment Given for Bone and Joint Infection	Omadacycline	treatment	2	recruiting
NCT04927637	ICG 24h Prior to Operative Treatment of Orthopaedic Infection	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT05732558	Augmented Reality Navigation System (Endosight) for the Guidance of Bone Biopsy	No drug interventions	diagnostic	Not Available	completed
NCT04563325	Oral-only Antibiotics for Bone and Joint Infections in Children	Amoxicillin Clavulanic acid Dicloxacillin	treatment	4	active_not_recruiting
NCT03082066	Soft Tissue and Bone Diameter in Children and Adults for Intraosseus Access	No drug interventions	Not Available	Not Available	completed
NCT02814591	Development of a Non-invasive Assessment of Human Bone Quality Using Spatially Offset Raman Spectroscopy	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT03335592	Cost of Off-label Antibiotics in Osteoarticular Infections	No drug interventions	Not Available	Not Available	terminated
NCT04746001	Artificial Intelligence in the Diagnosis of Orthopaedic Conditions, Particularly Bone Tumours and Infection	No drug interventions	Not Available	Not Available	unknown_status
NCT05883995	Avis-PHAGEinLYON Clinic	No drug interventions	Not Available	Not Available	recruiting