Severe Acute Respiratory Syndrome (SARS) (DBCOND0128915)

Identifiers

Synonyms
SARS (Severe Acute Respiratory Syndrome) / Respiratory Syndrome, Acute, Severe / Severe Acute Respiratory Syndrome / SARS (Disease) / Pneumonia due to SARS-associated coronavirus / SARS-CoV-1 infection / SARS / Severe acute respiratory syndrome (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04629703
Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety of Fostamatinib in COVID-19 Subjectstreatment3completed
NCT04476979
Comparison of Tocilizumab Plus Dexamethasone vs. Dexamethasone for Patients With Covid-19treatment2completed
NCT04497454
Mechanical Ventilation Strategy for Coronavirus Disease 2019 (COVID-19)No drug interventionstreatmentNot Availableunknown_status
NCT04327505
Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19No drug interventionstreatment2 / 3terminated
NCT04290871
Nitric Oxide Gas Inhalation for Severe Acute Respiratory Syndrome in COVID-19.treatment2withdrawn
NCT04540185
A Phase 3 Randomized Double Blind Efficacy and Safety Study of Oral Polio Vaccine and NA-831 for Covid-19prevention3unknown_status
NCT04664075
Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19)No drug interventionsNot AvailableNot Availableterminated
NCT04559113
Methylprednisolone in COVID-19 Patients (Methyl19LGH)treatmentNot Availableunknown_status
NCT04374734
Quantification of Radiological Pulmonary Involvement in Acute Respiratory FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT04659486
Adolescents With COVID-19/MIS-C at HCFMUSPNo drug interventionstreatmentNot Availableunknown_status
NCT04978025
Colloidal Silver, Treatment of COVID-19treatmentNot Availableunknown_status
NCT04517630
Renal Biomarkers in AKI and COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT04560257
High Flow Nasal Cannula HFNC In Covid-19 PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT04456426
Characteristics of Patients With COVID-19 in Meta State, ColombiaNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04443673
Glycine Supplement for Severe COVID-19No drug interventionstreatmentNot Availableterminated
NCT04558476
Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilationtreatment2active_not_recruiting
NCT04382391
Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory SymptomsNo drug interventionstreatmentNot Availableterminated
NCT04784481
Ivermectin Reproposing for Mild Stage COVID-19 Outpatientstreatment1 / 2completed
NCT04838795
Sisonke (Together): OPEN LABEL TRIAL COVID-19prevention3completed
NCT04366908
Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrometreatment2completed
NCT04728802
Proxalutamide Treatment for Hospitalized COVID-19 Patientstreatment3completed
NCT05097677
Follow-up of Covid-19 Long Term SequelaeNo drug interventionsNot AvailableNot Availableunknown_status
NCT04361461
Use of Hydroxychloroquine Alone or Associated for Inpatients With SARS-CoV2 Virus (COVID-19)treatment3withdrawn
NCT04328961
Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP)prevention2 / 3completed
NCT04306393
Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19treatment2completed
NCT04615052
Home-based Exercise in COVID-19 SurvivorsNo drug interventionstreatmentNot Availableunknown_status
NCT04644159
Longitudinal Follow-up of a Population Cohort in a French City With High SARS-CoV-2 Circulation, in Early 2020 [COVID-19]No drug interventionsNot AvailableNot Availablecompleted
NCT05054075
Protocol Design for Evaluating the Immunity of Bivalve Fluids From Anodonta Cygnea in SARS and COVID-19treatment2unknown_status
NCT04853199
Quercetin In The Treatment Of SARS-COV 2treatment0completed
NCT04657406
Expanded Access to Zofin for Patients With COVID-19Not AvailableNot Availableavailable
NCT04822818
EFFICACY and SAFETY OF BEVACIZUMAB (ZIRABEV®) IN PATIENTS WITH SEVERE HYPOXEMIC COVID-19No drug interventionstreatment3completed
NCT05074719
Index Individuals in SARS-CoV-2 Prevention Research Studies (COVID-19 Index Individuals Companion Study)No drug interventionsNot AvailableNot Availablecompleted
NCT05107258
A Clinical Evaluation of Pine Trees Health Test System Including the Pine Trees Health Reader and COVID-19 Test for Point-of-CareNo drug interventionsNot AvailableNot Availablecompleted
NCT04584658
Dysphagia and Dysphonia Outcomes in SARS CoV-2 (COVID-19) Infection (DYADS Study)No drug interventionsNot AvailableNot Availableunknown_status
NCT04590274
Safety and Efficacy of Hydroxychloroquine for the Treatment & Prevention of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)prevention1withdrawn
NCT04649931
Differences in Exhaled Breath by Using Ion Mobility Spectrometry (IMS) in Subjects Tested for SARS-CoV-2 Infection (COVID-19 Disease)No drug interventionsNot AvailableNot Availablecompleted
NCT04853927
Proxalutamide Treatment for COVID-19 Patients in Intensive Care Unittreatment3withdrawn
NCT04720794
A Study To Evaluate The Performance of the Lucira Health All-In-One COVID-19 Test Kit vs Hologic Panther FusionNo drug interventionsdiagnosticNot Availablecompleted
NCT04480580
Seroprevalence of SARS-Cov-2 in the Setting of a Non-dedicated COVID-19 Hospital in a Low CoV-2 Incidence Area: Implications for SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT04446429
Anti-Androgen Treatment for COVID-19treatmentNot Availablecompleted
NCT04325646
Sero-epidemiological Study of the SARS-CoV-2 Virus Responsible for COVID-19 in FranceNo drug interventionsNot AvailableNot Availablecompleted
NCT04390412
Low Dose Radiotherapy in COVID-19 PneumoniaNo drug interventionssupportive_care1 / 2unknown_status
NCT04701710
Prophylaxis Covid-19 in Healthcare Agents by Intensive Treatment With Ivermectin and Iota-carrageenanprevention1 / 2completed
NCT04546581
Inpatient Treatment of COVID-19 With Anti-Coronavirus Immunoglobulin (ITAC)treatment3completed
NCT06002841
Extracellular Vesicles From Mesenchymal Cells in the Treatment of Acute Respiratory FailureNo drug interventionstreatment1 / 2not_yet_recruiting
NCT04365985
Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19treatment2terminated
NCT04432272
ANTIBODY-LEVEL BASED ANALYSIS OF COVID-19 CONVALESCENT SERUM (ABACCuS)treatment2terminated
NCT04385823
Use of High Flow Nasal Cannula Oxygen and Covid-19 Acute Hypoxemic Respiratory FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT04411602
Intermediate IND Severe Illness COVID-19 CPNo drug interventionstreatment1withdrawn
NCT04376684
Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Diseasetreatment2completed
NCT01056185
Respiratory Virus Hospitalization Study (FLU 003 Plus)No drug interventionsNot AvailableNot Availablerecruiting
NCT04602351
Communication in ICU During COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT04320511
Beaumont Quantitative Lung Function Imaging to Characterize Patients With SARS-COV 2No drug interventionsNot AvailableNot Availableterminated
NCT04602507
Ivermectin in Adults With Severe COVID-19.treatment2terminated
NCT04542915
COVID-19-Related Health and Practices Among Dental HygienistsNo drug interventionsNot AvailableNot Availablecompleted
NCT04318015
Hydroxychloroquine Chemoprophylaxis in Healthcare Personnel in Contact With COVID-19 Patients (PHYDRA Trial)prevention3completed
NCT04527432
COVID-19 Health Professional Impact StudyNo drug interventionshealth_services_researchNot Availableactive_not_recruiting
NCT04386070
Preventing Pulmonary Complications in Surgical Patients at Risk of COVID-19prevention3not_yet_recruiting
NCT04381936
Randomised Evaluation of COVID-19 Therapytreatment3recruiting
NCT00342524
Collection of Convalescent SARS Plasma by ApheresisNo drug interventionsNot AvailableNot Availablecompleted
NCT04315896
Hydroxychloroquine Treatment for Severe COVID-19 Pulmonary Infection (HYDRA Trial)treatment3completed
NCT04860258
COVID-19: A Study to Evaluate Safety, Reactogenicity and Immunogenicity of the SARS-CoV-2 mRNA Vaccine CVnCoV in Adults With Co-morbiditiesprevention3terminated
NCT04425863
Ivermectin, Aspirin, Dexamethasone and Enoxaparin as Treatment of Covid 19Not AvailableNot Availablecompleted
NCT00172263
The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and MonocytesNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00578825
A Multi-centre, Double-blinded, Randomized, Placebo-controlled Trial on the Efficacy and Safety of Lopinavir / Ritonavir Plus Ribavirin in the Treatment of Severe Acute Respiratory SyndrometreatmentNot Availableunknown_status
NCT04449276
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19prevention1completed
NCT04581889
Prevalence of Antibodies Against SARS-CoV-2 Virus That Causes COVID-19 in Tübingen ChildrenNo drug interventionsNot AvailableNot Availablecompleted
NCT04470544
Camostat Mesilate Treating Patients With Hospitalized Patients With COVID-19treatment2recruiting
NCT04490850
COVID-19 Seroprevalence Study in French GuianaNo drug interventionspreventionNot Availablecompleted
NCT04627623
Prevalence and Risk Factors of COVID-19 in the Upper Silesian AgglomerationNo drug interventionsNot AvailableNot Availableunknown_status
NCT04480333
Safety, Tolerability and Pharmacokinetics of Inhaled Nanoparticle Formulation of Remdesivir (GS-5734) and NA-831treatment1unknown_status
NCT06287554
Effect of Early Implementation of Prone PositioningNo drug interventionsNot AvailableNot Availablecompleted
NCT04515147
A Dose-Confirmation Study to Evaluate the Safety, Reactogenicity and Immunogenicity of Vaccine CVnCoV in Healthy Adults for COVID-19prevention2completed
NCT04838847
A Study to Evaluate the Immunogenicity and Safety of the SARS-CoV-2 mRNA Vaccine CVnCoV in Elderly Adults Compared to Younger Adults for COVID-19prevention3withdrawn
NCT04636671
Methylprednisolone vs. Dexamethasone in COVID-19 Pneumonia (MEDEAS RCT)treatment3completed
NCT03225807
Implementation of Lung Protective Ventilation in Patients With Acute Respiratory FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT03465085
Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDStreatment3completed
NCT04444700
A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to (SARS-CoV-2) COVID-19 PandemicNo drug interventionstreatment3completed
NCT00150475
Contamination During Removal of Two Different Personal Protective SystemsNo drug interventionseducational_counseling_trainingNot Availablecompleted
NCT04745442
Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19No drug interventionstreatment2completed
NCT04433949
Best Supportive Care With or Without Low Dose Whole Lung Radiation Therapy for the Treatment of COVID-19No drug interventionstreatment3active_not_recruiting
NCT04425213
Obesity and Mortality of Critically Ill Patients With COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT04381819
Norwegian SARS-CoV-2 Study - Virological, Clinical and Immunological Characterisation of COVID-19No drug interventionsNot AvailableNot Availableunknown_status
NCT04366934
Study of the Pathogenesis of Olfactory Disorders in COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT04324463
Anti-Coronavirus Therapies to Prevent Progression of Coronavirus Disease 2019 (COVID-19) Trialtreatment3completed
NCT00073086
Evaluation and Treatment of Severe Acute Respiratory Syndrome (SARS)No drug interventionsNot AvailableNot Availablewithdrawn
NCT04335786
Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Diseasetreatment4terminated
NCT04357730
Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infectiontreatment2completed
NCT04402957
LSALT Peptide vs. Placebo to Prevent ARDS and Acute Kidney Injury in Patients Infected With SARS-CoV-2 (COVID-19)treatment2completed
NCT00215826
Study of Alferon® LDO (Low Dose Oral) in Normal Volunteerstreatment2completed
NCT04402060
A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19treatment1 / 2completed
NCT04328129
Household Transmission Investigation Study for COVID-19 in Tropical RegionsNo drug interventionsscreeningNot Availablecompleted
NCT04674189
A Study to Evaluate the Safety and Immunogenicity of Vaccine CVnCoV in Healthy Adults in Germany for COVID-19prevention3completed
NCT04395144
COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEssNo drug interventionstreatmentNot Availablecompleted
NCT04462367
Northeast COVID-19 and Pregnancy Study GroupNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04412746
Covid-19 and Diabetes in West of AlgeriaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04839146
Safety and Tolerability of COVID-19 Vaccine (ABNCoV2)No drug interventionsprevention1completed
NCT04378452
Assessment of the Psycho-social Impact of COVID-19 OutbreakNo drug interventionsNot AvailableNot Availablecompleted
NCT05074017
COVAG - Covid-19 Antigen Study - the Diagnostic Efficacy of SARS-CoV-2 Rapid Detection TestsNo drug interventionsNot AvailableNot Availablecompleted
NCT04695704
Efficacy of Montelukast in Mild-moderate Respiratory Symptoms in Patients With Long-COVID-19:treatment3terminated
NCT04492891
Cyclosporine For The Treatment Of COVID-19(+)treatment2completed
NCT04382768
Inhaled Ibuprofen to Treat COVID-19treatmentNot Availableunknown_status
NCT05004181
Safety and Immunogenicity of RNA-based Vaccines Against SARS-CoV-2 Variants in Healthy Participantsprevention2completed