NCT03951402
Effect of a Multiple-dose Oral Administration of CG5503 PR on the Electrical Activity of the Heart in 48 Healthy Men and Women treatment 1 completed NCT04350502
Pharmacokinetics and Pleural Fluid Penetration of Amoxicillin and Clavulanic Acid in Patients With Pleural Infections other Not Available completed NCT02696954
Study of Artemether-lumefantrine, Amodiaquine and Primaquine in Healthy Subjects treatment 1 / 2 terminated NCT03076151
Pharmacokinetic Study of Adoport® (Tacrolimus) in Patients With de Novo Kidney Transplantation other 4 completed NCT03059511
Pharmacokinetics of Nalbuphine After Intravenous and Intranasal Administration in Infants treatment 1 terminated NCT05367011
Therapeutic Monitoring of Antibiotics in Intensive Care Patients: a Cohort Study PopTDM-ICU No drug interventions Not Available Not Available not_yet_recruiting NCT04617509
A Study in Healthy Subjects to Evaluate Pharmacokinetics and Food Effect After Dosing of GS-248 No drug interventions treatment 1 completed NCT04820049
F573 Ia Clinical Trial No drug interventions other 1 completed NCT03011996
To Investigate PK and PD of CJ-12420, Clarithromycin, Amoxicillin After Multiple Dose Administration basic_science 1 completed NCT06344858
Characterization of the Temporal Profile of the Anti-nociceptive Effect of Ketamine Bolus Measured With ANI Not Available Not Available completed NCT06378125
Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes other 1 recruiting NCT03437265
A Pharmacokinetic Study of PLENVU® in Healthy Subjects treatment 1 completed NCT03344627
Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients treatment Not Available completed NCT03882762
A Clinical Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of Cebranopadol treatment 1 completed NCT03979989
Drug-drug Interaction Study to Evaluate the Effect of Omeprazole on CG5503 (Tapentadol) treatment 1 completed NCT03714568
Pharmacokinetic and Tolerance Study of TQ-A3326 in Healthy Participants. No drug interventions other 1 unknown_status NCT00743912
Open-Label Study to Evaluate the Effect of Rifaximin on Midazolam in Normal Healthy Volunteers other 1 completed NCT04959110
Citrate Pharmacokinetics in Critically Ill Liver Failure Patients Receiving CRRT No drug interventions diagnostic Not Available completed NCT04708795
Clinical Trial on Pharmacokinetic and Tolerability of AP701 No drug interventions other 1 completed NCT03958123
Evaluation of the Effects of Multiple Doses of Cebranopadol on the Electrical Activity of the Heart in Healthy Subjects treatment 1 completed NCT06471023
A Pharmacokinetic Study of Single Oral Doses of Six Different Vitamin C Product Forms No drug interventions basic_science Not Available active_not_recruiting NCT00745264
Multi-Centre, Open-Label, Two Segment, Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise No drug interventions Not Available 1 completed NCT03951987
Investigation How CG5503 is Taken up and Excreted From the Body After 2 Minutes Intravenous Infusion With and Without Oral Co-administration of Charcoal treatment 1 completed NCT01091532
A Study In Healthy People Of Multiple Doses Of UK-396,082 Given By Mouth, To Investigate The Safety, Toleration And Time Course Of Blood Concentration Of UK-396,082 And Its Effects. basic_science 1 completed NCT04735913
Effects of Metabolic Enzymes and Transporter Gene Polymorphisms on the Pharmacokinetics and Metabolism of Oral Abiraterone Acetate in Healthy Chinese Adults other 0 unknown_status NCT01082796
Cytochrome P450 2C19 Variant is Related to Pharmacokinetics of Glipizide Extended Release Tablet in Chinese Subjects health_services_research Not Available completed NCT05258474
Safety and Pharmacokinetics of Oral Controlled-ileocolonic-release Nicotinamide (CICR-NAM) other 1 completed NCT06524674
Clinical Study to Compare the Effect of an Oral Rehydration Solution on the Rate of Absorption of Functional Ingredients No drug interventions basic_science Not Available completed NCT06126562
A Pharmacokinetic Study of Lanifibranor in Healthy Adult Chinese Subjects treatment 1 completed NCT04326881
A Study to Compare Pharmacokinetic and Safety Profiles of Different Formulations of SHR-1314 After Subcutaneous Injection in Healthy Subjects other 1 unknown_status NCT00681395
Study to Compare the Bioavailability of ABT-335 and Rosuvastatin From ABT-143 Relative to That From the Co-administration of ABT-335 and Rosuvastatin Calcium treatment 1 completed NCT04080895
Pharmacokinetic Study of Artemether-lumefantrine and Amodiaquine in Healthy Subjects treatment 1 recruiting NCT04531150
Safety, Tolerability, and Pharmacokinetics of Single Ascending Oral Doses of INV-101 in Healthy Male and Female Subjects No drug interventions treatment 1 completed NCT05938608
A Study to Assess the Availability of Oral Primaquine and Its Inert Metabolite, Carboxyprimaquine, in the Body treatment 1 withdrawn NCT04667507
Pharmacokinetics of Aqueous Dexamethasone treatment 4 completed NCT05852340
A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants treatment 1 completed NCT06650930
Pharmacokinetics of Oral Calcium Carbonate in Parturients No drug interventions other 0 not_yet_recruiting NCT06562946
The Study to Assess the Pharmacokinetics of Pimicotinib in Subjects with Mild and Moderate Hepatic Impairment Relative to Subjects with Normal Hepatic Function other 1 enrolling_by_invitation NCT03396445
Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001) treatment 1 completed NCT06500793
Single and Multi-Dose Study, Pharmacokinetics of Oxycodone and PF614 Co-Administered with Nafamostat (PF614-MPAR-102) treatment 1 not_yet_recruiting NCT05090280
Pharmacokinetics of Oxycodone and PF614 Co-Administered with Nafamostat (PF614-MPAR-101) treatment 1 completed NCT05488678
Ceftibuten/VNRX-7145 in Participants With Varying Degrees of Renal Function basic_science 1 completed NCT00844103
Study to Investigate the Safety, Tolerability and Pharmacokinetics of Multiple Doses of AZD8566. No drug interventions basic_science 1 completed NCT00901290
Determine the Effects of C-administration of AZD7325 and an Oral Contraceptive in Healthy Female Subjects Not Available 1 suspended NCT03967964
Pharmacokinetics of a Novel Vaginal Delivery System for Testosterone and Dehydroepiandrosterone (DHEA) treatment 1 completed NCT05076864
Levosimendans Pharmacokinetics in Intensive Care Patients. An Observational Study. No drug interventions Not Available Not Available recruiting NCT05179564
Renal Function Assessment in Critically Ill Children No drug interventions diagnostic Not Available completed NCT00868764
An Investigation on the Effect of Age and BMI on the Pharmacokinetics of Transdermal Granisetron other 1 completed NCT00747721
Pharmacokinetics of Dexmedetomidine During Prolonged Infusion in ICU basic_science 1 completed NCT03843502
A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics basic_science 1 completed NCT01415102
A First In Human Study In Healthy People To Evaluate Safety, Toleration And Time Course Of Plasma Concentration Of Single Inhaled Doses Of PF-05212372. basic_science 1 completed NCT03161002
Impact of Biomarkers on Pharmacokinetics and Pharmacodynamics of Ticagrelor No drug interventions Not Available Not Available unknown_status NCT03766984
Pharmacokinetic Non-interaction Study With a Fixed-dose Combination Tablet With Tramadol and Diclofenac basic_science 1 completed NCT06277284
Clinical Study of MG-K10 Humanized Monoclonal Antibody Injection in Healthy Adult Subjects prevention Not Available active_not_recruiting NCT05576584
Safety, Tolerability and Pharmacokinetic Characteristics Evaluation on GST-HG121 Tablets No drug interventions other 1 recruiting NCT01131533
Intraocular Pharmacokinetics of Erythropoietin After Single Intravitreal Injection in Human No drug interventions treatment Not Available unknown_status NCT05469854
A Study to Investigate the Pharmacokinetics and ECG Effects of Linaprazan Glurate No drug interventions basic_science 1 recruiting NCT05716854
Electrophysiological Effects of Potential QT Prolonging Drugs other 1 completed NCT01309854
Effects of Administration of Fostamatinib on Blood Concentrations of Pioglitazone in Healthy Subjects basic_science 1 completed NCT00767351
Variation in Serum Levels of Metformin in Patients With Reduced Renal Function No drug interventions Not Available Not Available completed NCT00863551
Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial treatment 4 completed NCT05617651
Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-T treatment 1 not_yet_recruiting NCT04092751
Study to Evaluate the Effect of SCY-078 (Ibrexafungerp) on the PK of Pravastatin in Healthy Subjects other 1 completed NCT02097953
Influence of Rifampin Co-Administration on the Pharmacokinetic Profile of Daptomycin treatment 0 completed NCT02534753
A Pharmacokinetics Study of Intravenous Ascorbic Acid treatment 1 completed NCT03582553
Safety and Pharmacokinetics of an Extract of Naringenin No drug interventions other 0 completed NCT05633147
Effect of Clarithromycin on PK of Linaprazan, Linaprazan on PK of Clarithromycin and Linaprazan on PK of Midazolam basic_science 1 completed NCT00730145
A Single Dose Study Investigating The Elimination Of PD-0332334 In Patients Receiving Regular Hemodialysis Not Available 1 completed NCT02359045
Study in Healthy Subjects to Compare the Concentrations of the Omega-3 Fatty Acids EPA and DHA in Blood When Delivered as Three New Capsules in Relation to the Epanova® Capsule Under Fasting and Fed Conditions basic_science 1 completed NCT04565145
Biomarker Changes and Anxiolytic Effects-Phase 2 treatment 2 completed NCT04397445
Clinical Study to Investigate the Urinary Excretion of N-nitrosodimethylamine (NDMA) After Ranitidine Administration basic_science 1 completed NCT05486598
A Study of Diet Influence of AL8326 in Chinese Healthy Adult Subjects No drug interventions treatment 1 unknown_status NCT02568098
Pharmacokinetic and Mosquito-Lethal Effects of Ivermectin (IVM), Primaquine (PQ), Dihydroartemisinin-Piperaquine (DHA-PQP) and Albendazole (ABZ) in Healthy Subjects No drug interventions treatment 1 completed NCT00556998
A Multiple-Dose Study To Evaluate The Pharmacokinetics And Safety Of Voriconazole In Immunocompromised Adolescents prevention 2 completed NCT04724798
Population Pharmacokinetics of Tigecycline in Patients Treated With ECMO No drug interventions Not Available Not Available unknown_status NCT01404598
Pharmacokinetics Study: Determination of Naproxcinod and Its Metabolites After Oral Administration in Male basic_science 1 completed NCT04906005
Pharmacokinetics and Safety of Gadopiclenol in Japanese Healthy Volunteers other 1 completed NCT05143905
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD7503 in Healthy Participants No drug interventions treatment 1 completed NCT02671097
Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate Not Available 1 completed NCT05329597
Study on Umorestat Hydrogen Sulfate Capsule in Patients With Locally Advanced/Metastatic Pancreatic Cancer No drug interventions Not Available Not Available unknown_status NCT04389983
Ketone Levels Achieved After Medium Chain Triglyceride (MCT) Oil No drug interventions health_services_research Not Available completed NCT04435483
A Study of Acalabrutinib Suspension to Evaluate Relative Bioavailability and Proton-pump Inhibitor Effect in Healthy Volunteers treatment 1 completed NCT05232461
A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects treatment 1 completed NCT04651361
Naldebain for Pain Control After Bariatric Surgery treatment 2 / 3 unknown_status NCT05370261
Pharmacological Profile of Different Berberine Formulations, and Effects on Blood Sugar Levels No drug interventions treatment Not Available completed NCT01952561
Expanded Use PK of Dapivirine Vaginal Ring prevention 1 completed NCT01579461
A Study to Investigate the Effect of Mirabegron (YM178) on Subjects With Mild or Moderate Hepatic Impairment Compared to Healthy Subjects basic_science 1 completed NCT02217761
Pharmacokinetic Study in Patients Receiving Posaconazole Therapy in Taiwan No drug interventions Not Available Not Available unknown_status NCT01953861
A Study to Evaluate Whether Food Has an Effect on the Uptake of Solifenacin and Tamsulosin When Administered in a Combination Tablet basic_science 1 completed NCT05259228
Therapeutic Drug Monitoring of Tyrosine Kinase Inhibitor in Patients With Chronic Myeloid Leukemia No drug interventions Not Available Not Available recruiting NCT01569828
Multiple Dose Pharmacokinetics of LCZ696 and Its Metabolites in Subjects With Severe Renal Impairment vs. Matched Healthy Subjects With Normal Renal Function No drug interventions treatment 2 completed NCT01789528
A Study to Investigate the Effect of Administration of Ceftazidime-avibactam (CAZ-AVI) and Ceftaroline Fosamil -Avibactam (CXL) on the Intestinal Flora of Healthy Volunteers No drug interventions basic_science 1 completed NCT04961593
PK/PD of Caspofungin in Children Severe Infection Not Available Not Available recruiting NCT03410771
Bioelectrical Impedance Analysis as a Bedside Tool to Estimate Volume of Distribution of Hydrophilic Antimicrobials in Critically Ill Patients No drug interventions Not Available Not Available completed NCT02092571
A Pharmacokinetic Study to Evaluate the Bioequivalence of 2 Progesterone Vaginal Rings in Postmenopausal Women other 1 completed NCT04045171
Population Pharmacokinetics of Tacrolimus in Nephrotic Syndrome Not Available Not Available unknown_status NCT05328778
Pharmacokinetics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade in Patients During Laparoscopic Surgery treatment 4 unknown_status NCT01976078
Development of Voriconazole Pharmacokinetics and Metabolism in Children and Adolescents Not Available Not Available completed NCT01084278
Healthy and Renal Impairment Study of Colcrys (Colchicine, USP) basic_science 4 completed NCT05436678
A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult Subject treatment 1 completed NCT05125588
Fasting Comparative Bioavailability Study of 2 Meloxicam 15 mg Tablets in Healthy Volunteers Under Fasting Condition other 1 completed NCT00834288
A Study to Compare the Bioavailability of Two Tramadol Hydrochloride Tablet Products (50 mg and 200 mg, Respectively) at Steady-state Under Fasting Conditions treatment 1 completed NCT04729088
Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects other 1 withdrawn NCT04672707
Study on the Pharmacokinetics of Bromine Hexane Hydrochloride Tablets in Healthy Adults treatment 1 not_yet_recruiting NCT02956109
Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Volunteers other 1 completed NCT01655056
A Study to Evaluate the Safety and Tolerability of YM150 in Healthy Caucasian and Japanese Male and Female Subjects, and to Assess the Effect That Gender May Have on Its Actions in the Body basic_science 1 completed NCT03737656
Characterization of the Pharmacokinetics of a Vaginal Ring With 2.0 g Progesterone in Post-menopausal Women other 1 completed NCT02126956
Mass Balance, Pharmacokinetics, and Metabolism of 14C-labeled ACT-128800 Administered to Healthy Male Subjects Not Available 1 completed NCT00722956
Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin basic_science 1 completed NCT02107885
Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Participants. No drug interventions basic_science 1 completed NCT01959685
A Dose Escalating Study to Determine the Tolerability and PK of a Single Dose of Androxal treatment 1 completed NCT05949385
A Study to Assess the Effect of Itraconazole Capsules on the Pharmacokinetics of ZX-7101A Tablets in Healthy Adult Subjects in China treatment 1 not_yet_recruiting NCT02306915
PK, PD, Safety and Tolerability of Lipegfilgrastim in Healthy Japanese and Caucasian Participants other 1 completed NCT03632915
Pharmacokinetics of Antiepileptics in Patients on CRRT Not Available Not Available completed NCT00714337
Formulation and Food Effect Study of AZD1386 in Healthy Volunteers basic_science 1 completed NCT04971837
Interaction Between Cannabidiol, Meal Ingestion, and Liver Function No drug interventions basic_science Not Available completed NCT03789032
Study to Evaluate the Effect of Rabeprazole on the Pharmacokinetics of Vadadustat treatment 1 completed NCT00856752
Evaluation of the Pharmacokinetics of NRL972 Following Pre-Administration of Rifampicin and Cyclosporine diagnostic 1 completed NCT01181700
A Study To Estimate The Time Course Of PF-00241939 Concentration In The Blood After Dosing With Oral Inhalation From Dry Powder Inhalers No drug interventions basic_science 1 completed NCT06574100
Relative Bioavailability of Two Orally Administered CBD Formulations in Healthy Male Adults basic_science 1 recruiting NCT04100759
A Comparative Pharmacokinetic and Pharmacodynamic Study of Sildenafil in Adult Smokers and Non Smokers treatment 1 / 2 completed NCT04142359
PK Sub-Study of QUILT-3.032 (CA ALT-803-01-16) and of QUILT-2.005 (CA ALT-803-01-14) Not Available Not Available terminated NCT05125575
Fed Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers other 1 completed NCT05065775
Bioavailability of Intranasal Dexmedetomidine No drug interventions basic_science 4 completed NCT01017042
Pharmacokinetic Study of an Acute Gout Regimen basic_science 1 completed NCT05041699
PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel No drug interventions diagnostic 1 / 2 active_not_recruiting NCT03258099
Association of Genetic Polymorphisms With Capecitabine-based Chemotherapy Toxicities in Chinese Solid Tumor Patients No drug interventions Not Available Not Available unknown_status NCT00676299
A Safety and Dose-finding Study of JNJ-26483327, a Drug in Development for Cancer, for Patients With Advanced and/or Refractory Solid Malignancies. No drug interventions treatment 1 completed NCT05648799
Pharmacokinetics, Safety and Efficacy Study of GP30341 (GEROPHARM, Russia) treatment Not Available completed NCT02242006
Antimicrobial Pharmacokinetics in Critically Ill Adults During Sustained Low Efficiency Dialysis (SLED) No drug interventions Not Available Not Available completed NCT00969449
Pharmacokinetics Study Comparing Naproxen Sodium Extended Release and Naprelan treatment 1 completed NCT03672149
Safety and Therapeutic Drug Monitoring of Cefazolin in Continuous Renal Replacement Therapy other 1 unknown_status NCT06426836
Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) No drug interventions other Not Available recruiting NCT01086813
Phase I, Single Centre, Study to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD3043 basic_science 1 withdrawn NCT05856513
Pharmacokinetics of ZSP1273 in Participants With Hepatic Impairment No drug interventions basic_science 1 completed NCT02558413
Phase 1 Safety and Pharmacokinetics Study of Single Ascending Doses of BTA-C585 in Healthy Volunteers No drug interventions treatment 1 completed NCT05627518
Relative Bioavailability of Linaprazan for the Test Formulation vs. Reference Formulation No drug interventions basic_science 1 completed NCT00704119
Study Evaluating the Pharmacokinetic Profile of RhuDex® in a Tablet Formulation No drug interventions Not Available 1 terminated NCT06252519
Pharmacokinetic Profile of N-Acetyl Cysteine No drug interventions basic_science Not Available active_not_recruiting NCT01276119
The First Clinical Study to Test Safety, Blood Levels and Other Effects of CDP6038 in Healthy Males Not Available 1 completed NCT02561741
Pharmacokinetic, Bioavailability, and Safety Study of COV155 Administered in Healthy Subjects Under Fed and Fasted Conditions No drug interventions Not Available 1 completed NCT01214941
Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral Tramadol basic_science 4 completed NCT04183517
A Two-part Pharmacokinetic Study of PXS-5382A in Healthy Adult Males No drug interventions treatment 1 completed NCT04669717
Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies treatment 4 recruiting NCT03529617
Pharmacokinetics of Liposomal Amphotericin B in Critically Ill vs. Non-critically Ill Hematological Patients: Exploration of Covariates No drug interventions Not Available Not Available recruiting NCT05172817
Study to Compare PK & Safety of Advixa With Humira in Healthy, Adult Subject Followed by Efficacy & Safety Study in RA Patients treatment 2 / 3 unknown_status NCT02127034
Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects basic_science 1 completed NCT03770234
Clinical Study in Healthy Men to Investigate the Uptake of Buprenorphine and Its Elimination From the Body After Dermal Application as Patches for 96 Hours and for 72 Hours treatment 1 completed NCT05527834
Food Effect on Ceftibuten/VNRX-7145 in Healthy Participants treatment 1 completed NCT01636024
To Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Ascending Doses of Inhaled AZD7594 basic_science 1 completed NCT00723424
Drug Interaction Study - Effect of AZD5672 on the Pharmacokinetics of Digoxin basic_science 1 completed NCT05433896
Evaluating the Effects of Omeprazole on the Pharmacokinetics of XS004 (Dasatinib) Tablets in Healthy Adult Subjects Under Fasting Conditions other 1 completed NCT01489696
A Study to Evaluate Cardiovascular Interactions Between Mirabegron and Tamsulosin Not Available 1 completed NCT06379958
Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects other 1 recruiting NCT05330858
Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants basic_science 1 completed NCT02957435
Pharmacokinetics Study of Eplerenone Coated Tablets other 1 withdrawn NCT04335435
Avenanthramide and Saponin Bioavailability in Oat Bran No drug interventions basic_science Not Available completed NCT02802735
Study to Evaluate the Pharmacokinetics of Single and Multiple Doses of Apremilast in Healthy Adult Male Korean Subjects treatment 1 completed NCT03012763
Oral Pharmacokinetics of Sulfasalazine, Paracetamol, Fexofenadine and Valsartan Using Different Administration Mediums basic_science 1 completed NCT02560363
A Study to Compare the Pharmacokinetics of Different Formulations of AZD9977 and the Influence of Food in Healthy Male Subjects basic_science 1 withdrawn NCT05353686
A Trial Investigating the Effect of 4 Weeks Dosing of XEN-D0501 on Blood Glucose Reduction in Patients With Diabetes treatment 2 completed NCT04463030
Antioxidant Bioavailability No drug interventions basic_science Not Available unknown_status NCT04764630
Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone other 1 completed NCT05124730
Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female Volunteers other 1 completed NCT03857230
The Safety and Pharmacokinetics of Primapur and Gonal-f other 1 completed NCT04806230
Serum Concentrations of Antidepressant Drugs in Pregnant Women - a Naturalistic Study Not Available Not Available completed NCT02308748
Ability of Late Sodium or Calcium Current Block to Balance the ECG Effects of Potassium Current Block basic_science 1 completed NCT03919448
A Phase I Study Comparing Pharmacokinetics and Safety of Bevacizumab other 1 completed NCT06291948
A Clinical Study With Adalimumab Biosimilar other 1 completed NCT05266248
Pilot Study Characterizing the Pharmacokinetic Profile of a Novel Encapsulated Caffeine Beverage in the Fed and Fasted States No drug interventions basic_science 1 completed NCT00298857
A Pharmacokinetic Study to Compare the Dosing of Valproic Acid in Subjects With Different Body Weights treatment 4 terminated NCT03309657
Pharmacokinetics of Ceftolozane/Tazobactam in Plasma and Cerebrospinal Fluid basic_science 1 / 2 completed NCT00714857
Population Pharmacokinetics of Dexmedetomidine in ICU Patients Not Available 2 / 3 completed NCT05873426
Mass Balance Study of [14C]ZSP1273 in Healthy Adult Male Subjects in China No drug interventions basic_science 1 completed NCT03632226
Evaluation of a Novel PET Radioligand to Image OGA No drug interventions Not Available Not Available completed NCT01318265
Effect of Ketoconazole on Regorafenib (BAY73-4506) Pharmacokinetics Not Available 1 completed NCT04219865
Safety, Tolerance and Pharmacokinetics Study of Compound Edaravone Injection No drug interventions basic_science 1 completed NCT04969965
To Evaluate the Comparative Pharmacokinetics of Orally Administered EQ143 in Different Racial and Ethnic Populations No drug interventions treatment 1 completed NCT05042674
Clinical Study on Rapid Antioxidant Protection and Immune Modulating Effects. No drug interventions basic_science Not Available unknown_status NCT04668274
JOTROL PK, Safety, and Food Effect Assessment basic_science 1 completed NCT05005520
Study of DTRI-031 in Healthy Volunteers No drug interventions treatment 1 completed NCT02205320
A Comparative, Crossover, Pharmacokinetic, Pharmacodynamic and Safety Study of Three Forms of PEG-G-CSF in Normal Healthy Volunteers treatment 1 unknown_status NCT00709982
A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM) /Ethinyl Estradiol (EE) in Healthy Women. prevention 1 completed NCT03083782
Drug Interaction Study of Apixaban With Cyclosporine and Tacrolimus basic_science 1 completed NCT00867282
A Study to Estimate the Time Course of PF-00241939 Concentration in the Blood Following Dosing by Oral Inhalation From Dry Powder Inhalers No drug interventions basic_science 1 completed NCT03766282
Pharmacokinetics in Extracorporeal Membrane Oxygenation No drug interventions Not Available Not Available unknown_status NCT01851473
Interactions Between Intravenous Cocaine and Acetazolamide or Quinine diagnostic 1 completed NCT01736527
Tear Fluid Levels of Loteprednol Etabonate Ophthalmic Gel 0.5% Following a Single Instillation Not Available 1 completed NCT05611827
Pharmacological Profile of Different Quercetin Formulations No drug interventions treatment Not Available completed NCT02367027
Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension of Rivaroxaban Under Fed Conditions to 10 mg of an Immediate Release Tablet Under Fasting Conditions Not Available 1 completed NCT05125627
Fasting Bioequivalence Study of 2 Progesterone Soft Capsules 200 mg in 66 Healthy Female Subjects Under Vaginal Route other 1 completed NCT05277376
Pharmacokinetic (PK) Evaluation of Bemotrizinol (6%) in a Sunscreen Maximum Usage Trial basic_science 3 completed NCT00644176
A Randomized, Open Label, Clinical Trial of the Pharmacokinetics of Azithromycin Following a Single Dose of Azithromycin Sustained Release (2 Gram) or Commercial Azithromycin Tablet (500 mg) to Cancer Patients That Require Lung Surgery basic_science 2 completed NCT05123976
Fasted Bioequivalence Study of 2 Olanzapine Film-coated Tablets, 5 mg, in Healthy, Adult Male and Female Subjects. other 1 completed NCT03622476
Pharmacokinetic (PK)Research on Chinese Children of Hemophilia No drug interventions treatment 4 unknown_status NCT05223660
A Phase I Pharmacokinetics Study for KT07 Capsule No drug interventions health_services_research 1 completed NCT04023760
Drug Interaction Study of Apixaban With Cyclosporine or Tacrolimus in Transplant Recipients other 4 completed NCT03633760
Different Level of Single-dose and Multiple-dose Bilastine PK Study in Chinese Population basic_science 1 unknown_status NCT00983294
Drug-Drug Interaction Study of Colchicine and Azithromycin basic_science 1 completed NCT03739294
Urine Concentrations of Vilanterol After Inhaled Administration of Vilanterol/Fluticasone Furoate basic_science 2 completed NCT00833391
Relative Bioavailability Study for GSK1838262 (Gabapentin Enacarbil) Not Available 1 completed NCT05167591
Detection of Paracetamol Concentration in Patients Using Regular Medication- a Validation Study for a Novel Technique No drug interventions diagnostic Not Available withdrawn NCT00693862
Pharmacokinetic Study With Repeated Doses of Stalevo treatment 1 completed NCT02191462
A Study of the Pharmacokinetics of Three Dosages of Niagen in Healthy Subjects No drug interventions Not Available 1 completed NCT01187862
Pharmacokinetic Study to Investigate Low-dose Combinations of a Cocktail of Seven Drugs for Simultaneous Phenotyping of Cytochromes diagnostic 1 completed NCT03612180
Evaluation of Metoprolol Pharmacokinetics in Patients Receiving Hi Flux Hemodialysis Not Available Not Available completed NCT05098080
Hutrukin to Analyze Safety and PK in Healthy Volunteers No drug interventions treatment 1 completed NCT04178629
Ceftobiprole's Cerebrospinal Fluid Penetration in Patients With External Ventricular Derivation (CEFTO-EVD) No drug interventions Not Available Not Available unknown_status NCT01639729
Effect of Delivery Route on PK of Sufentanil NanoTab basic_science 1 completed NCT00614029
A Study to Evaluate the Pharmacokinetics and Bioequivalence of Sumatriptan Delivered Via the Intraject System No drug interventions basic_science 1 completed NCT02484729
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 After Single Ascending Doses to Healthy Males basic_science 1 completed NCT00709189
Bioequivalence Study of the Oral Contraceptive Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women. prevention 1 completed NCT05775692
Population Pharmacokinetics of Fluconazole in the Treatment of Neonatal Fungal Infectious Disease Not Available Not Available recruiting NCT03737292
Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy treatment 4 recruiting NCT04183192
Pharmacodynamic Biomarkers to Support Biosimilar Development: Interleukin-5 Antagonists other 1 completed NCT02147392
Assessment of [11C]ER176 to Image Translocator Protein in Brain and Whole Body of Healthy People No drug interventions diagnostic 0 completed NCT03557840
Plasma Protein Binding and PK/PD of Total and Unbound Temocillin Non-ICU Patients other Not Available unknown_status NCT03369340
Nicotine Pharmacokinetics and Pharmacodynamics, Safety and Tolerability of P3P No drug interventions other Not Available completed NCT01735240
Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally. basic_science 1 completed NCT01240967
To Compare the Pharmacokinetics of a Single Oral Dose of TC-5214 in Subjects With Renal Impairment and With Subjects With Normal Renal Function Not Available 1 completed NCT02673567
To Assess Pharmacokinetics, Safety and Tolerability of TEV-48125 in Japanese and Caucasian Healthy Subjects After a Single Subcutaneous (SC) Administration of TEV-48125 other 1 completed NCT05394701
Comparing the Pharmacological Profile of Formulations Containing Omega 3 Fatty Acids No drug interventions treatment Not Available completed NCT00520104
Determination of Drug Interactions of Certain Nasal Medications With Intranasal Ketamine treatment 1 unknown_status NCT00176072
BlueCQ Bioavailability No drug interventions Not Available Not Available completed NCT05898672
A Study to Learn About the Study Medicine Called Nirmatrelvir/Ritonavir in People Who Are Healthy Volunteers Co-administered the Medicine Rosuvastatin basic_science 1 completed NCT04759768
Pharmacokinetic Evaluation of Intranasal Nalmefene basic_science 1 completed NCT01188668
Open Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Aripiprazole When Coadministered To Healthy Subjects basic_science 4 completed NCT06471868
Study to Evaluate Pharmacokinetic and Pharmacodynamic Drug Interactions and Safety of IY-HCR21 and IY-MIC No drug interventions treatment 1 active_not_recruiting NCT00915668
A Study to Evaluate the Pharmacokinetic Drug Interaction Between Multiple Doses of JNJ-31001074 and a Single Dose of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Women Not Available 1 withdrawn NCT05267769
Clinical Trial on Pharmacokinetics and Tolerability of AP707 No drug interventions other 1 completed NCT02117869
The Effect of Low Furanocoumarin Grapefruit Hybrid Juice Consumption on Midazolam Pharmacokinetics No drug interventions Not Available 4 completed NCT01676246
Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine basic_science 1 completed NCT00748046
Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton basic_science 1 completed NCT05099510
Natrunix Safety PK Study in Healthy Volunteers No drug interventions treatment 1 unknown_status NCT01657981
A Study to Find Out How YM150 is Absorbed Into and Eliminated From the Body in Healthy Male Subjects basic_science 1 completed NCT01568281
Bioequivalence Study Comparing Arimidex Tablet and Anastrozole ODF in Japanese Healthy Male Subjects treatment 1 completed NCT03722381
Evaluation of Amlodipine Pharmacokinetics in Patients Receiving Hi Flux Hemodialysis Not Available Not Available withdrawn NCT04004195
Study to Investigate Safety, Absorption, Elimination, and Drug Effect of BAY2327949 in Participants With Different Renal Function Status No drug interventions other 1 completed NCT05652595
Double-blind, Randomized Comparative Cross-sectional Study of Pharmacodynamics and Pharmacokinetics of Drugs GP40141 basic_science 1 recruiting NCT06095895
Model Informed preciSion doSIng tO iNdividualise and Optimize Pharmacotherapeutic Treatment No drug interventions Not Available Not Available not_yet_recruiting NCT05490095
Randomized Crossover of SVG101(Dispersible Tab. of Everolimus) and Afinitor 5mg in Healthy Adults treatment 1 completed NCT05964114
First Time Right of Vancomycin treatment Not Available not_yet_recruiting NCT01222455
A Study of Fostamatinib in Subjects With Impaired Hepatic (Liver) Function basic_science 1 completed NCT01208155
Study in Healthy Males to Assess Bioavailability of 4 Different Fostamatinib Tablets basic_science 1 completed NCT05187455
Pharmacokinetics of Sugammadex for the Reversal of Moderate Neuromuscular Blockade in Patients During Renal Transplantation treatment 4 unknown_status NCT04501250
Comparative Study of Rinsulin® NPH, Suspension for Subcutaneous Administration, 100 IU/ml (GEROPHARM LLC, Russia) and Humulin® NPH, Suspension for Subcutaneous Administration, 100 IU/ml (Lilly France, France) Using the Euglycemic Hyperinsulinemic Clamp Method basic_science Not Available completed NCT04181008
Pharmacokinetics of Amiloride Nasal Spray in Healthy Volunteers basic_science 0 completed NCT01037608
Effects of Sativex(Registered Trademark) and Oral THC on Attention, Affect, Working Memory, Reversal Learning, Physiology and Brain Activation other 1 completed NCT01682408
Assess Pharmacokinetics of Fostamatinib in Fed and Fasted State in Combination With Ranitidine to Assess Bioavailability basic_science 1 completed NCT04250038
Association of Cefepime Trough Levels With Clinical Efficacy and Neurotoxicity in Patients With Febrile Neutropenia No drug interventions Not Available Not Available unknown_status NCT03606538
MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function basic_science 1 not_yet_recruiting NCT01496443
TAK-875 Glimepiride Drug-Interaction Study Not Available 1 completed NCT05509543
Study to Evaluate the Safety and the Pharmacokinetics of IY-NT-T treatment 1 completed NCT02059343
Pharmacokinetics of Dexmedetomidine in Children During Cardiopulmonary Bypass (CPB) No drug interventions Not Available Not Available completed NCT00810303
Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2 basic_science 1 completed NCT01017003
Pharmacokinetic Study With Colchicine in Healthy Volunteers basic_science 1 completed NCT05755503
Toxicokinetics of Protein-bound Uremic Toxins in ESRD Patients No drug interventions Not Available Not Available recruiting NCT01478503
To Evaluate the Blood and Urine Concentration and the Safety and Tolerability of Increasing Repeated Doses of Mirabegron (YM178) OCAS in Healthy Young and Elderly Males and Healthy Young and Elderly Females Not Available 1 completed NCT01055964
a Comparative Pharmacokinetic Study of Two Oral Formulations of Tacrolimus in Renal Allograft Recipients Not Available 3 completed NCT02272764
A Drug-Drug Interaction Study of ALKS 5461 in Healthy Volunteers treatment 1 completed NCT00836264
Pharmacogenomics Analysis of Morphine Pharmacokinetics in Pediatric Tonsillectomy and Adenoidectomy No drug interventions Not Available Not Available completed NCT05036421
Effect of Glucuronosyltransferase (UGT) Genetic Variation on Pharmacokinetics of Empagliflozin other 3 completed NCT05147402
Food Effects on Bioavailability of MDMA in Healthy Volunteers basic_science 1 completed NCT01118702
A Study to Explore Plasma Levels of CONCERTA, Ritalin-SR and Novo-Methylphenidate ER-C in Healthy Volunteers basic_science 1 completed NCT00572884
Metabolism of the Insecticide Permethrin No drug interventions basic_science Not Available completed NCT01815684
A Study to Assess the Safety, Tolerability and Effects of Single Ascending Doses of ASP3652 in Healthy Subjects No drug interventions basic_science 1 completed NCT05801484
Pharmacokinetics and Pharmacodynamics of Linezolid Continuous and Intermittent Administration No drug interventions treatment Not Available recruiting NCT04189484
Pharmacodynamic Biomarkers to Support Biosimilar Development: PCSK9 Inhibitors other 1 completed NCT02790684
A Study Assessing the Mass Balance of a Single Oral Dose of [14C] DS-8500a in Healthy Subjects No drug interventions other 1 completed NCT01913379
Drug-drug Interaction Study With MDV3100 (ASP9785) and Gemfibrozil and Itraconazole Not Available 1 completed NCT00749879
Crossover Study of the Safety and PK Properties of Proellex® basic_science 1 completed NCT00638079
Evaluating the Effect of Food on Absorption of Megace ES Not Available 1 completed NCT01953887
A Study to Compare the Amount of Drug in the Blood After a Single Tablet EC905 Containing Solifenacin and Tamsulosin is Taken by Healthy Males Compared to Separate Tablets of Solifenacin and Tamsulosin basic_science 1 completed NCT05480787
Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU treatment 4 unknown_status NCT00176033
Influence of Drug Transporter Expression on the Pharmacokinetics of the HIV Protease Inhibitor Kaletra No drug interventions Not Available Not Available completed NCT01465633
Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 50 μg/ 75 μg Tablets basic_science 1 completed NCT00645554
A Single Dose, Cross-over Bioequivence Study Comparing Galantamine IR (Immediate Release) Table and Galantmine OS (Oral Solution) in Healthy Volunteers treatment 1 completed NCT06122454
A Phase Ic/IIb Study to Evaluate the Efficacy，Safety and Pharmacokinetics of HST in Patients With CHB treatment 1 / 2 recruiting NCT02054754
Assessment of Single Doses of Oral Dexanabinol in Healthy Subjects basic_science 1 completed NCT03135951
Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC) Chemotherapy treatment 1 completed NCT03258151
Association of Genetic Polymorphisms With Docetaxel-based Chemotherapy Toxicities in Chinese Solid Tumor Patients No drug interventions Not Available Not Available unknown_status NCT01081353
Pharmacokinetic Study Comparing Aspirin and Effervescent Aspirin treatment 1 completed NCT04031053
Itraconazole Pharmacokinetic With and Without Efavirenz Using the Capsule Formulation as Part of Talaromycosis Treatment in HIV-infected Adults No drug interventions Not Available Not Available unknown_status NCT05967377
Evaluating the Pharmacokinetic Parameters and Relative Bioavailability of Sorafenib (XS005) in Healthy Male Subjects other 1 completed NCT02436577
Study to Assess the Bioequivalence Between Ticagrelor Orodispersible Tablets and Ticagrelor Immediate-release Tablets in Japanese Subjects basic_science 1 completed NCT05373277
KF2019#1-trial: Effects of a Thrombocyte Inhibitor on a Cholesterol-lowering Drug basic_science 1 unknown_status NCT05257447
Pharmacokinetic and Bioequivalence Comparison of Baclofen and Chlorzoxazone Administered Individually or Concurrently basic_science 1 completed NCT05503147
Sativex® and Gentamicin for Optimized Pharmagological Treatment in Older Patients (CanPan) treatment 1 unknown_status NCT01501747
The Placebo Effect May Involve Modulating Drug Bioavailability Not Available Not Available completed NCT01958047
A Study to Assess the Effect of Race on How a Single Dose of ASP3652 is Taken up, Metabolized and Distributed Through the Bodies of Young, Healthy Male and Female Subjects, and Its Safety and Tolerability No drug interventions basic_science 1 completed NCT06519045
PK of Codeine and Metabolites in Human Fingerprint Sweat, Oral Fluid, Blood and Urine No drug interventions Not Available Not Available active_not_recruiting NCT01040845
A Pharmacokinetic Study of Colchicine With an Oral Contraceptive basic_science 1 completed NCT04459598
A Study of the Effect of a Moderate CYP3A Inducer Efavirenz on Quizartinib Pharmacokinetics in Healthy Participants treatment 1 completed NCT05503498
Pharmacokinetic Model of Fibrinogen Plasma Levels After Fibrinogen Administration No drug interventions Not Available Not Available completed NCT02068105
A Study of ALKS 5461 in Healthy Volunteers No drug interventions treatment 1 completed NCT00983905
Drug-Drug Interaction Study of Colchicine and Theophylline basic_science 1 completed NCT01650597
A Single Ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-42165279 in Healthy Male Participants treatment 1 completed NCT03953183
Product Use and Adaptation, Safety and Tolerability of P3P in Adult Healthy Smokers Switching to it No drug interventions basic_science Not Available completed NCT05686083
Pharmacokinetics of Two Fatty Acid Ketone Esters No drug interventions basic_science Not Available completed NCT04295161
A Study Designed to Evaluate the Pharmacokinetic Profile of Abiraterone treatment 1 completed NCT03324061
Study to Evaluate the Safety, Tolerability, and PK of Fulvestrant After IM Administration other 1 completed NCT03070561
Evaluating Peanut Immunotherapy Dissolving Film in Healthy Subjects No drug interventions other 0 completed NCT00984061
Drug-Drug Interaction Study of Colchicine and Clarithromycin basic_science 1 completed NCT02974361
Impact of Excipients on Pharmacokinetics of OXPzero(TM) Ibuprofen basic_science 1 completed NCT03530228
A Phase 1 Study of Tegoprazan on Healthy Male Volunteers basic_science 1 unknown_status NCT01420211
Influence of the OATP1B1 and OATP1B3 Genotype on the Hepatic Uptake of Primovist® basic_science 1 / 2 completed NCT03683511
Nomograms for Optimization of Amikacin First Dose in Critically Ill Patients Using a Population Pharmacokinetics Model No drug interventions Not Available Not Available completed NCT02790671
A Study to Determine the Effects of Itraconazole on the Pharmacokinetics (PK) of DS-8500 in Healthy Subjects treatment 1 completed NCT03765671
Elafibranor Pharmacokinetic Parameters in Hepatic Impaired Patients basic_science 1 completed NCT00985478
First in Man Study With SLV342 No drug interventions treatment 1 terminated NCT05176678
Immunological Effect of Increasing Doses of Natural Peptide No drug interventions basic_science Not Available unknown_status NCT05478278
An Evaluation of Psilocybin's Effect on Cardiac Repolarization and the Effect of Food on Psilocybin's Pharmacokinetics treatment 1 completed NCT01002378
The Effect of Food (High Fat and Low Fat Breakfast) on the Pharmacokinetics of Regorafenib screening 1 completed NCT05665478
Population Pharmacokinetics/Pharmacodynamics of Carbapenems in Febrile Neutropenia Patients No drug interventions treatment Not Available not_yet_recruiting NCT05569278
Safety and Pharmacokinetics of GEH200486 in Healthy Volunteers No drug interventions basic_science 1 completed NCT02386488
Pharmacokinetic Properties of Vortioxetine in Healthy Young Chinese Men and Women treatment 1 completed NCT02175407
A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects basic_science 1 completed NCT01050309
An Open-label, Single-dose, Three Period Study to Determine the Pharmacokinetic Parameters of Hexaminolevulinate (HAL) Hydrochloride After Vaginal, Enema and Intravenous Administration of Healthy Female Volunteers Not Available 1 completed NCT03841409
Peak Plasma Levels of Bupivacaine After an Erector Spinae Block (ESP) No drug interventions Not Available Not Available completed NCT00984009
A Drug-Food Interaction Study Between Colchicine and Grapefruit Juice basic_science 1 completed NCT02894385
Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201) other 1 completed NCT00176085
Pharmacokinetics of THCCOOH and Its Acyl-glucuronide After Intravenous Administration of THCCOOH No drug interventions Not Available Not Available completed NCT03484585
Rogaratinib (BAY1163877) Human Mass Balance Study treatment 1 completed NCT04459585
A Study of the Effect of Quizartinib on the Pharmacokinetics of the P-gp Substrate Dabigatran Etexilate in Healthy Participants treatment 0 completed NCT00550485
Pharmacokinetic and Pharmacodynamic Effects of Escitalopram Depending on Genetic Polymorphisms of the ABCB1-gene basic_science Not Available completed NCT05481385
Bioequivalence Study of Ezetimibe Tablets Under Fed Conditions in Healthy Subjects No drug interventions other 1 unknown_status NCT05452785
A Comparative Bioavailability Study of DFD-29 Capsules 40 mg Versus SOLODYN® Tablets 105 mg, Under Fasting & Fed Conditions in Healthy Adult Human Subjects other 1 completed NCT05373615
Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy basic_science 1 active_not_recruiting NCT04406415
Oral Nafamostat in Healthy Volunteers treatment 1 completed NCT00828815
TMC125-TiDP2-C188: A Phase I, Open-label Trial to Investigate the Pharmacokinetic Effect of Multiple-dose TMC125 on Buprenorphine and Norbuprenorphine Administered in HIV-negative Patients on Stable Buprenorphine/Naloxone Maintenance Therapy. treatment 1 completed NCT00983515
Drug-Drug Interaction Between Colchicine and Ritonavir basic_science 1 completed NCT02755532
Bupivacaine Pharmacokinetics in Ultrasound-guided Axillary Brachial Plexus Block. basic_science Not Available completed NCT05217732
Study to Assess the Safety, Tolerability and Pharmacokinetics of ZX-7101A and the Food Effect in Healthy Volunteers No drug interventions treatment 1 completed NCT00709332
A Drug Interaction Study of Folic Acid and Oral Contraceptive Tablets Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) in Healthy Women. prevention 1 completed NCT01420952
Imaging of Brain Receptors Using (11C)mGlu1 No drug interventions diagnostic 1 terminated NCT01167452
Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations treatment 4 completed NCT00616252
Antiretroviral Drug Levels During and After Pregnancy No drug interventions Not Available Not Available completed NCT05180500
Safety and Acceptability of Q GRFT Nasal Spray for COVID-19 Prophylaxis No drug interventions basic_science 1 completed NCT01189500
Open-Label Drug Interaction Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) 100mg On The Pharmacokinetics Of Tamoxifen When Coadministered To Healthy Post-Menopausal Female Subjects basic_science 4 completed NCT00779259
Drug - Drug Interaction Study Between Quinine Sulfate and Theophylline basic_science 1 completed NCT02512575
A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of AZD9567. basic_science 1 completed NCT03070470
CiPA Phase 1 ECG Biomarker Validation Study other 1 completed NCT00856570
A Clinical Study to Determine the Effect of YM178 on the Pharmacokinetics of Warfarin in Healthy Subjects basic_science 1 completed NCT03136770
A Randomized, Open-label, Two-way Crossover Study to Assess the Pharmacokinetics and Safety of CK-30 600 mg (Compound K) No drug interventions basic_science Not Available completed NCT06072170
Single Ascending Doses of Kratom in Healthy Nondependent Adults With Opioid Experience No drug interventions basic_science 1 completed NCT05381870
Bioequivalence Study of Ezetimibe Tablets Under Fasting Conditions in Healthy Subjects No drug interventions other 1 unknown_status NCT01721070
Effect of Ketoconazole on Sufentanil NanoTab Pharmacokinetics basic_science 1 completed NCT04911270
Clinical Decision Support Tool for Vancomycin Dosing in Children No drug interventions treatment Not Available active_not_recruiting NCT00983242
Drug-Drug Interaction Between Colchicine and Verapamil ER basic_science 1 completed NCT02462642
Effect of Bacopa Monniera Extract on Cognition and Anxiety and Exploration of PK Properties No drug interventions supportive_care Not Available completed NCT00621699
Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects basic_science 1 completed NCT00746499
Pharmacokinetic Study of Raltegravir in Healthy Premenopausal Women. Not Available 1 completed NCT02585999
The Pharmacokinetics of 12 Week Continuous Patch Use No drug interventions other Not Available completed NCT00710606
Comparison of Serum Contraceptive Hormone Levels Between Normal Weight and Obese Users of the NuvaRing® Not Available Not Available completed NCT02209506
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MLN3126 in Healthy Japanese and Non-Japanese Participants No drug interventions treatment 1 terminated NCT03002506
Pharmacokinetics of Ceftolozane/Tazobactam in Patients With Burns other 4 terminated NCT06497049
Open Randomized Study of Comparative Pharmacokinetics and Biosimilarity of GP40221 (GEROPHARM LLC, Russia) and Ozempic®. treatment 1 completed NCT00947349
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 201335 as Softgel Capsule in Naive Hepatitis C Virus (HCV) Patients treatment 2 completed NCT05125549
Fasted Bioequivalence Study of Clopidogrel Film-coated Tablets, 75 mg in 48 Healthy, Adult Male and Female Subjects. other 1 completed NCT00855049
A Randomized Crossover Study to Determine the Pharmacokinetics of Intranasally Administered Acetaminophen in Healthy Adults basic_science Not Available withdrawn NCT03767036
Administration of Tramadol and Ketorolac Separately and Simultaneously to Assess a Potential Pharmacokinetic Interaction treatment 1 completed NCT02169713
Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects basic_science 1 completed NCT01046513
PET Imaging of Nicotinic Acetylcholine Receptors No drug interventions Not Available Not Available completed NCT05847218
Phase 1 Clinical Trial of RHN-001 in Healthy Adult Volunteers No drug interventions other 1 completed NCT05855018
A Study of Atropine Sulfate in Healthy Chinese Volunteers other 1 recruiting NCT04131218
Pharmacokinetics and Pharmacodynamics of Sugammadex in Reversal of Vecuronium-induced Neuromuscular Blockade treatment 4 unknown_status NCT04319718
Safety and Pharmacokinetics of Two Vaginal Film Formulations Containing the Integrase Inhibitor MK-2048 No drug interventions basic_science 1 completed NCT00474019
Phase 1 Pharmacokinetics of Intravenous Nexium in Children treatment 1 completed NCT03800641
A Study of Dexmedetomidine Pharmacokinetics for Preoperative Sedation prevention 4 completed NCT05931341
Pharmacokinetic Profile of Rosemary Extract Supplement No drug interventions other Not Available not_yet_recruiting NCT02215941
Study to Characterize the Pharmacokinetics and Safety of TV-45070 Ointment in Healthy Volunteers other 1 completed NCT05124717
Fed Bioequivalence Study of 2 Metformin 500 mg Prolongued Release Tablets in 28 Healthy Male and Female Volunteers other 1 completed NCT06427317
Routinely Collected Clinical Data and Evaluation of Antimicrobial Target Attainment No drug interventions Not Available Not Available recruiting NCT03956134
Pharmacokinetic Characterization of Two Novel CG5503 Tablet Formulations in Healthy Volunteers treatment 1 completed NCT04489134
P-glypoprotein Inhibition Effect on the Pharmacokinetics of Two Tacrolimus Formulations: Prolonged and Extended-release No drug interventions other 2 unknown_status NCT00915434
A Study to Characterize the Pharmacokinetics and Effect of Food on JNJ-31001074 in Healthy Volunteers Not Available 1 completed NCT01034124
Mechanisms Underlying Drug-Diet Interactions basic_science Not Available completed NCT04874324
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of Oral WCK 2349 No drug interventions other 1 completed NCT03198624
Pharmacokinetics of Oral Capsule in Healthy Japanese vs. Caucasian Subjects No drug interventions treatment 1 completed NCT02351024
Phase I Study PK Study With OXP005 and Naprosyn Not Available 1 completed NCT03631316
Pharmacokinetic Parameters of Innovative Valganciclovir Versus Generic Valganciclovir prevention Not Available completed NCT05517616
The Absorption, Metabolism and Excretion of [14C]APG-2575 in Healthy Subjects treatment 1 completed NCT00983216
Drug-Drug Interaction Study Between Colchicine and Ketoconazole basic_science 1 completed NCT03440216
Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care Units other Not Available unknown_status NCT00810316
Evaluate Pharmacokinetics Of Two Different Pharmaceutical Oral Formulations Of Alprazolam And A Clonazepam Tablet In Mexican Healthy Population other 1 completed NCT01226316
Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules treatment 1 active_not_recruiting NCT03161496
Impact of Biomarkers on Pharmacokinetics and Pharmacodynamics of Direct Oral Anticoagulants No drug interventions Not Available Not Available unknown_status NCT02957396
Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Subjects other 1 completed NCT06360796
Study of Pharmacokinetics and Metabolism on [(14)C]ADC189 No drug interventions basic_science 1 recruiting NCT05310058
Pharmacokinetics of C6 Ketone Di-ester No drug interventions basic_science Not Available completed NCT04777058
Pharmacokinetics of Isavuconazole in Patients in the Intensive Care Unit No drug interventions Not Available Not Available completed NCT02820935
Study to Evaluate the Effect of Cytochrome P450 (CYP) 3A Inhibition and Induction on the Pharmacokinetics of CC-220 in Healthy Subjects treatment 1 completed NCT00482963
A Study of the Drug Interactions Between a Hormonal Emergency Contraception and an HIV Medication treatment 1 completed NCT02085863
A Phase I Study in Young Healthy Women to Investigate the Effects of Laquinimod on Standard Oral Contraceptive When Both Treatments Are Given Together other 1 completed NCT03011463
Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1 basic_science 1 completed NCT03326986
Safety, Tolerability and Pharmacokinetics Study of MK-7252 in Healthy Adult Participants (MK-7252-001) No drug interventions treatment 1 completed NCT01549639
Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion No drug interventions Not Available Not Available completed NCT05253339
The Expected Advantage of Administering Prophylactic Antibiotics Using Target- Concentration Controlled Infusion No drug interventions treatment Not Available recruiting NCT00721422
A Single Dose Study Investigating the Elimination as Well as the Tolerability of PD 0332334 in Healthy Subjects as Compared to Patients With Impaired Kidney Function. Not Available 1 terminated NCT01214122
A Drug-Drug Interaction Study Between AZD9668 and Warfarin to Study the Effect of AZD9668 on the Metabolism and Effect of Warfarin basic_science 1 withdrawn NCT01260025
Tolerability and Pharmacokinetics of M2ES in the Treatment of Advanced Solid Tumor treatment 1 completed NCT02601625
A Study to Assess the Pharmacokinetics and Safety of Single Doses of Anifrolumab in Healthy Subjects basic_science 1 completed NCT04092725
Study to Evaluate the Effect of SCY-078 on the PK of Dabigatran in Healthy Subjects other 1 completed NCT00681525
A Multiple-Dose Pharmacokinetic Interaction Study Between ABT-335, Atorvastatin and Ezetimibe treatment 1 completed NCT01163630
Food Interaction Study To Assess the Effect of Food on the Pharmacokinetics of Esomeprazole 20 mg/Acetylsalicylic Acid 81 mg basic_science 1 completed NCT01953848
A Study to Evaluate How Tamsulosin (at 1 Dose) and Solifenacin (at 2 Different Doses) Are Taken up From the Intestine, Distributed Through the Body and Eliminated From the Body When Administered in Combination as a Single Tablet (Called EC905) basic_science 1 completed NCT00721448
An Open-Label, Single and Multiple Dose Pharmacokinetic Study of 90 mg and 180 mg Doses of AZD6140 in Healthy Volunteers basic_science 1 completed NCT02030457
A Study to Investigate the Pharmacokinetics and Safety of Beclomethasone Dipropionate Administered by Breath-Actuated Inhaler and Metered-Dose Inhaler in Healthy Adults other 1 completed NCT03560557
Optimization of PK/PD Target Attainment for Meropenem in Critically Ill Patients With Sepsis No drug interventions Not Available Not Available completed NCT06425757
Study on Pharmacokinetics of Single Injection of Ciprofol in Patients With Moderate to Severe Hypoproteinemia No drug interventions other 4 recruiting NCT01121926
A Study to Compare the Bioavailability of 300 mg Trazodone Hydrochloride Extended-release Caplets and 100 mg Trazodone Hydrochloride Immediate-release Tablets at Steady State treatment 1 completed NCT00549666
A Randomized, Placebo-Controlled, Two-Period, Crossover Study to Evaluate the Effect of Lurasidone HCl on Oral Contraceptive Pharmacokinetics in Healthy Female Subjects Not Available 1 completed NCT05460065
Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers No drug interventions other 1 unknown_status NCT04631874
A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg" treatment 1 completed NCT02456974
Antibiotic Dosing in Pediatric Intensive Care No drug interventions Not Available Not Available recruiting NCT01018420
Pharmacokinetic and Exploratory Electrocardiogram (ECG) Study basic_science 1 completed NCT05588531
Study on Tolerance, Pharmacokinetics and Drug Interaction of YK-1169 in Healthy Volunteers basic_science 1 completed NCT00983931
Drug-Drug Interaction Study Between Colchicine and Cyclosporine basic_science 1 completed NCT05747573
A Study to Compare Pharmacokinetics of GB1211 basic_science 1 completed NCT02968576
Bioequivalence of Tenofovir and Emtricitabine Following Overencapsulation basic_science Not Available completed NCT01124760
Open Label Study, Assessing the Effect of Diltiazem or Ketoconazole on the Pharmacokinetics of AZD9742 in Healthy Volunteers treatment 1 completed NCT06362460
Mass Balance Study of [14C]RAY1216 in Healthy Adult Male Subjects in China No drug interventions basic_science 1 completed NCT05650294
Uptake of an Omega-3 Oil in Healthy Adults No drug interventions basic_science Not Available completed NCT03033394
Beta-lactam Pharmacokinetics in Secondary Care Not Available Not Available completed NCT05437094
Effect of Coadministration of Itraconazole on the Pharmacokinetics of CRD-740 treatment 1 completed NCT04183491
Pharmacodynamic Biomarkers to Support Biosimilar Development: Interferon Beta-1A Products other 1 completed NCT00731562
An Investigation Of The Effects Of Food On The Absorption Of A Varenicline Controlled Release Formulation Not Available 1 completed NCT03690362
VNRX-5133 With VNRX-5022 in Subjects With Varying Degrees of Renal Impairment basic_science 1 completed NCT01692262
Investigating Safety, Tolerability and Efficacy of AZD5363 in Prostate Cancer. screening 1 completed NCT03895229
The Effect of Morning Versus Evening Administration on The Pharmacokinetics and Pharmacodynamics of Empagliflozin other 1 completed NCT01954589
Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206 other 1 completed NCT05406492
Population PK of Antibiotics, Sedative and Analgesics, and Antiplatelet Drugs During ECMO No drug interventions Not Available Not Available unknown_status NCT00812292
TMC278-TiDP38-C145: A Bioavailability Study in Healthy Adult Volunteers to Evaluate 3 Pediatric Formulations of TMC278 (a Solution, a Suspension, and Granules) Compared to an Adult Tablet Formulation treatment 1 completed NCT05142592
IPG7236 in Patients With Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT05795192
SB17170 Phase1 Trial in Healthy Volunteer No drug interventions treatment 1 completed NCT04126044
A SINGLE-DOSE, 2-ARM, PHARMACOKINETIC STUDY OF PF-06439535 (CN) AND EUROPEAN UNION SOURCED BEVACIZUMAB IN CHINESE HEALTHY MALE VOLUNTEERS other 1 withdrawn NCT00709644
Bioequivalence Study of the Oral Contraceptive (OC) Tablet Containing Norgestimate (NGM)/Ethinyl Estradiol (EE) With or Without Folic Acid in Healthy Women. prevention 1 completed NCT04207840
Study of Drug Exposure in Systemic Circulation of Primatene Mist by Oral Inhalation, Versus Epinephrine Injection by Intramuscular Injection and ProAir by Oral Inhalation in Healthy Individuals treatment 4 completed NCT05125640
Fasting Bioequivalence Study of 2 Oral Progesterone Soft Capsules 200 mg in 48 Healthy Female Subjects other 1 completed NCT00709267
Bioavailability Study of Folic Acid in Healthy Women prevention 1 completed NCT02668367
Safety and Pharmacokinetics Study of Multiple Ascending Doses of BTA-C585 in Healthy Volunteers No drug interventions treatment 1 completed NCT03629067
Combination of Fimasartan/Amlodipine/Hydrochlorothiazide in Healthy Male Subjects No drug interventions treatment 1 completed NCT04176367
An Bioequivalence Study Comparing Nicergoline 10 mg Tablet Manufactured in China With Nicergoline 10 mg Tablet Manufactured in Italy Under Fasted and Fed Conditions in Healthy Chinese Participants other 1 completed NCT03252067
Tear Concentrations and Pharmacokinetics of Azithromycin Eye Drops in Healthy Volunteers treatment 1 unknown_status NCT00621101
Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects basic_science 1 completed NCT02206204
Study of Selexipag and Its Metabolite ACT-333679 on Cardiac Repolarization in Healthy Male and Female Subjects Not Available 1 completed NCT03920904
Peak Plasma Levels of Bupivacaine After a Pecto-Intercostal Fascial Block Post-Sternotomy for Cardiac Surgery No drug interventions Not Available Not Available completed NCT04161404
Pharmacometabolomics of Andrographis Paniculata And Metformin In Healthy Volunteers Under Fasting Condition other 1 unknown_status NCT01072604
Pharmacokinetic Study Comparing Aspirin and Aspirin Granules treatment 1 completed NCT02169804
An Open-Label Study to Evaluate the Effect of Age Upon the Pharmacokinetics of Androxal treatment 1 completed NCT03145272
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Thai Pediatric Surgical Patients treatment 4 active_not_recruiting NCT02233972
A Drug-Drug Interaction Study To Investigate The Ginkgolides Meglumine Injection To Alter The Pharmacokinetics Of Midazolam basic_science 4 completed NCT05539872
Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar Rapid-Acting Insulin Aspart (I004) and NovoLog After Single-Dose Subcutaneous Administration to Healthy Volunteers treatment 2 / 3 completed NCT03340168
Kinetic Time Courses of Bisphenol-S in Volunteers No drug interventions basic_science Not Available unknown_status NCT00741169
TMC435350-TiDP16-C105: Phase I, 3-way Crossover, Drug-drug Interaction Between TMC435350 and Rifampin After Multiple Dosing. treatment 1 completed NCT00791869
Pharmacogenetics of Bupropion Metabolism No drug interventions Not Available Not Available completed NCT01082146
RI-AME Study OF [ISOTHIAZOLYL-3-14C]-LURASIDONE Not Available 1 completed NCT00915746
A Drug Interaction Study of JNJ-31001074 and Ketoconazole in Healthy Volunteers Not Available 1 completed NCT01465646
Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 100 μg/ 75 μg Tablets basic_science 1 completed NCT01786512
COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure treatment 2 completed NCT03522012
Phase I, Pharmacokinetic, Safety and Tolerability Study in Healthy Volunteers treatment 1 completed NCT00532012
Phase-I Study Evaluating the Pharmacokinetic Profile of RhuDex® No drug interventions basic_science 1 completed NCT05421312
Periarticular Penetration of Cefazolin and Clindamycin in Second Stage Revision Arthroplasty of the Hip No drug interventions prevention 4 unknown_status NCT05148312
Single-dose AQ001S PK Study in Healthy Volunteers treatment 1 completed NCT00752310
TMC114-TiDP29-C169: Bioavailability and Pharmacokinetics Trial Comparing Darunavir Pediatric Suspension Formulation to Current Darunavir Tablet treatment 1 completed NCT03776110
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GRT9906 Prolonged Release Tablets After Dose Escalation in Healthy Subjects No drug interventions treatment 1 completed NCT06480981
Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers No drug interventions other 1 recruiting NCT04684381
Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients basic_science 4 completed NCT03438981
Optimization of PK/PD Target Attainment for Ceftriaxone in Critically Ill Patients With Community-acquired Pneumonia. No drug interventions Not Available Not Available completed NCT05123781
Fasting Bioequivalence Study of 2 Metformin 1000 mg Prolonged Release Tablets in 28 Healthy Male and Female Volunteers other 1 completed NCT03337581
Pharmacodynamics and Pharmacokinetics of Dexmedetomidine in Pediatric prevention 4 unknown_status NCT05698095
Pharmacokinetics, Safety, and Tolerability of Intramuscular 5-MeO-DMT in Healthy Volunteers other 1 completed NCT02549014
A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of MK-1064 (MK-1064-001) treatment 1 completed NCT03715114
A Study to Assess the Safety and Pharmacokinetics of Oral Sodium Oligo-mannurarate (GV-971) in Healthy Chinese Subjects No drug interventions basic_science 1 unknown_status NCT01158755
Intensified Treatment Regimens for TB Meningitis: PK, PD and Tolerability Study treatment 2 completed NCT03844555
Elafibranor Pharmacokinetic Parameters in Renal Impaired Patients basic_science 1 completed NCT03614455
Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Participants basic_science 0 completed NCT03911050
Scavenging of Reactive Carbonyl Species by Apple Polyphenols in Human No drug interventions treatment Not Available completed NCT02561650
Pharmacokinetic, Bioavailability, and Safety Study of COV155 Administered in Healthy Subjects Under Fed and Fasted Conditions No drug interventions Not Available 1 completed NCT01464450
Pharmacokinetics Study of Oral Rivaroxaban in Healthy Participants treatment 1 completed NCT03519750
Pharmacokinetics of Intravenous, Rectal, Intravesical, Vaginal, and Transdermal Melatonin in Healthy Female Volunteers basic_science 1 completed NCT03727750
Evaluating QTc, PK, Safety of Gemtuzumab Ozogamicin (GO) in Patients With CD33+ R/R AML treatment 4 completed NCT03717623
Posaconazole Pharmacokinetics in Patients Receiving Chemotherapy or Stem Cell Transplants treatment 4 recruiting NCT03991208
Malarone Pharmacokinetics Under Simulated Physiologic Stressors of Deployment treatment 4 withdrawn NCT03145038
Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects other 1 completed NCT02170038
Clinical Study Investigating the Conversion of the Contraceptive Compound Norethisterone Within the Body Towards the Contraceptive Compound Ethinylestradiol basic_science 1 completed NCT01820143
Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety Not Available 1 completed NCT03480243
Study to Evaluate the Effect of Coadministered Erythromycin on the Pharmacokinetics and Safety of Padsevonil basic_science 1 completed