Cytochrome P-450 CYP2C19 Inducers (strength unknown)

Name
Cytochrome P-450 CYP2C19 Inducers (strength unknown)
Accession Number
DBCAT004484
Description

CYP2C19 enzyme inducers of unknown strength.

Drugs
DrugDrug Description
PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
AminoglutethimideAn adrenocortical steroid synthesis inhibitor used in the treatment of Cushing's syndrome.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
PrednisoneA corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
LumacaftorA protein chaperone used in combination with ivacaftor for the treatment of cystic fibrosis in patients who are homozygous for the F508del mutation in the CFTR gene.
Hydroxyprogesterone caproateA synthetic progestin used for the prevention of spontaneous preterm births in singleton pregnancies in women who have previously had a spontaneous preterm birth.
BarbitalA long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice...
SecobarbitalA barbiturate used for the short-term treatment of insomnia.
OpicaponeA catechol-O-methyltransferase inhibitor used as an adjunct treatment for Parkinson's Disease in adults currently receiving levodopa and a dopa decarboxylase inhibitor.
MidostaurinAn antineoplastic agent used to treat high-risk acute myeloid leukemia (AML) with specific mutations, aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematologic neoplasm (SM-AHN), or mast cell leukemia (MCL).
St. John's WortAn herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.
EfavirenzA non-nucleoside reverse transcriptase inhibitor used to treat HIV infection or prevent the spread of HIV.
NelfinavirA viral protease inhibitor used in the treatment of HIV infection.
NorethisteroneA synthetic second-generation progestin used for contraception, prevention of endometrial hyperplasia in hormone replacement therapy, and in the treatment of other hormone-mediated illnesses such as endometriosis.
HydrocortisoneA glucocorticoid used to treat corticosteroid-responsive dermatoses, endocrine disorders, immune conditions, and allergic disorders.
BudesonideA corticosteroid used to treat Crohn's disease, asthma, COPD, hay fever and allergies, and ulcerative colitis.
MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Prednisolone phosphateA corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
DabrafenibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
MitapivatA pyruvate kinase activator used to treat hemolytic anemia in adults with pyruvate kinase (PK) deficiency.
MavacamtenA myosin inhibitor used to treat obstructive hypertrophic cardiomyopathy.
PirtobrutinibA kinase inhibitor used to treat relapsed or refractory mantle cell lymphoma (MCL) after at least two lines of systemic therapy.
SparsentanAn endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy at risk of rapid disease progression.
LetermovirAn antiviral medication used for prophylaxis in adult transplant recipients at risk of cytomegalovirus (CMV) infection and disease.
RepotrectinibA tyrosine kinase inhibitor used to treat locally active or metastatic non-small cell lung cancer
NirogacestatA gamma-secretase inhibitor used to treat desmoid tumors
TovorafenibA type II RAF inhibitor used to treat pediatric low-grade glioma with BRAF gene mutations.
VorasidenibA isocitrate dehydrogenase type 1 (IDH1) and 2 (IDH2) inhibitor used to treat Grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1 or IDH2 mutation.
Drugs & Drug Targets
DrugTargetType
PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
PrimidoneCytochrome P450 2C19enzyme
PrimidoneCytochrome P450 2C9enzyme
PrimidoneCytochrome P450 3A4enzyme
PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
PrimidoneGlutamate receptor 2target
PrimidoneGlutamate receptor ionotropic, kainate 2target
PrimidoneGABA(A) Receptortarget
PrimidoneTransient receptor potential cation channel subfamily M member 3transporter
PrimidoneCytochrome P450 2E1enzyme
PrimidoneCytochrome P450 1A2enzyme
PrimidoneUDP-glucuronosyltransferases (UGTs)enzyme
PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PhenobarbitalCytochrome P450 2C19enzyme
PhenobarbitalCytochrome P450 2C9enzyme
PhenobarbitalCytochrome P450 2B6enzyme
PhenobarbitalCytochrome P450 2C8enzyme
PhenobarbitalCytochrome P450 1A2enzyme
PhenobarbitalCytochrome P450 3A4enzyme
PhenobarbitalATP-binding cassette sub-family C member 3transporter
PhenobarbitalBile salt export pumptransporter
PhenobarbitalATP-dependent translocase ABCB1transporter
PhenobarbitalMultidrug resistance-associated protein 1transporter
PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
PhenobarbitalATP-binding cassette sub-family C member 2transporter
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PhenobarbitalGlutamate receptor 2target
PhenobarbitalGlutamate receptor ionotropic, kainate 2target
PhenobarbitalCytochrome P450 2A6enzyme
PhenobarbitalCytochrome P450 2E1enzyme
PhenobarbitalCytochrome P450 3A5enzyme
PhenobarbitalCytochrome P450 1A1enzyme
PhenobarbitalCytochrome P450 2C18enzyme
PhenobarbitalCytochrome P450 3A7enzyme
PhenobarbitalCytochrome P450 4B1enzyme
PhenobarbitalNMDA receptortarget
PhenobarbitalNuclear receptor subfamily 1 group I member 2target
PhenobarbitalUDP-glucuronosyltransferase 1A1enzyme
PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
AminoglutethimideAromatasetarget
AminoglutethimideCytochrome P450 2C19enzyme
AminoglutethimideCytochrome P450 3A4enzyme
AminoglutethimideCholesterol side-chain cleavage enzyme, mitochondrialtarget
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidATP-dependent translocase ABCB1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acidEndoplasmic reticulum chaperone BiPtarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidOrganic anion transporter 3transporter
Acetylsalicylic acidSialidase-1target
Acetylsalicylic acid3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DexamethasoneGlucocorticoid receptortarget
DexamethasoneAnnexin A1target
DexamethasoneNitric oxide synthase, inducibletarget
DexamethasoneNuclear receptor subfamily 0 group B member 1target
DexamethasoneCytochrome P450 3A4enzyme
DexamethasoneCytochrome P450 3A5enzyme
DexamethasoneCytochrome P450 3A7enzyme
DexamethasoneBile salt export pumptransporter
DexamethasoneATP-dependent translocase ABCB1transporter
DexamethasoneATP-binding cassette sub-family C member 2transporter
DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DexamethasoneBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DexamethasoneCytochrome P450 1A1enzyme
DexamethasoneCytochrome P450 2A6enzyme
DexamethasoneCytochrome P450 2B6enzyme
DexamethasoneCytochrome P450 2C19enzyme
DexamethasoneCytochrome P450 2C8enzyme
DexamethasoneCytochrome P450 2E1enzyme
DexamethasoneCytochrome P450 3A43enzyme
DexamethasoneCytochrome P450 4A11enzyme
DexamethasoneNuclear receptor subfamily 1 group I member 2target
DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DexamethasoneAlbumincarrier
Dexamethasone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone11-beta-hydroxysteroid dehydrogenase 1enzyme
DexamethasoneOrganic anion transporter 3transporter
PrednisoneGlucocorticoid receptortarget
PrednisoneCytochrome P450 3A4enzyme
PrednisoneATP-dependent translocase ABCB1transporter
PrednisoneSolute carrier organic anion transporter family member 1A2transporter
PrednisoneCytochrome P450 2C19enzyme
PrednisoneAlbumincarrier
PrednisoneCytochrome P450 3A5enzyme
PrednisoneCorticosteroid-binding globulincarrier
PrednisoneCytochrome P450 3A Subfamilyenzyme
PrednisoneCytochrome P450 2A6enzyme
PrednisoneCytochrome P450 1B1enzyme
PrednisoneCytochrome P450 2B6enzyme
PrednisoneCytochrome P450 2C8enzyme
PrednisoneCytochrome P450 2C9enzyme
Prednisone11-beta-hydroxysteroid dehydrogenase 1enzyme
LumacaftorCytochrome P450 2B6enzyme
LumacaftorCytochrome P450 2C8enzyme
LumacaftorCytochrome P450 2C9enzyme
LumacaftorCytochrome P450 2C19enzyme
LumacaftorAlbumincarrier
LumacaftorCystic fibrosis transmembrane conductance regulatortarget
LumacaftorCytochrome P450 3A4enzyme
LumacaftorATP-dependent translocase ABCB1transporter
Hydroxyprogesterone caproateProgesterone receptortarget
Hydroxyprogesterone caproateCytochrome P450 3A4enzyme
Hydroxyprogesterone caproateCytochrome P450 3A5enzyme
Hydroxyprogesterone caproateCytochrome P450 2C19enzyme
BarbitalGamma-aminobutyric acid receptor subunit alpha-1target
BarbitalGamma-aminobutyric acid receptor subunit alpha-2target
BarbitalGamma-aminobutyric acid receptor subunit alpha-3target
BarbitalGamma-aminobutyric acid receptor subunit alpha-4target
BarbitalGamma-aminobutyric acid receptor subunit alpha-5target
BarbitalGamma-aminobutyric acid receptor subunit alpha-6target
BarbitalNeuronal acetylcholine receptor subunit alpha-4target
BarbitalNeuronal acetylcholine receptor subunit alpha-7target
BarbitalGlutamate receptor 2target
BarbitalGlutamate receptor ionotropic, kainate 2target
BarbitalCytochrome P450 3A4enzyme
BarbitalCytochrome P450 2C19enzyme
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
SecobarbitalCytochrome P450 2C8enzyme
SecobarbitalCytochrome P450 2C9enzyme
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
SecobarbitalGlutamate receptor 2target
SecobarbitalGlutamate receptor ionotropic, kainate 2target
SecobarbitalCytochrome P450 1A2enzyme
SecobarbitalNMDA receptortarget
SecobarbitalCytochrome P450 2C19enzyme
OpicaponeCytochrome P450 2C19enzyme
OpicaponeCytochrome P450 2C8enzyme
OpicaponeCatechol O-methyltransferasetarget
OpicaponeSolute carrier organic anion transporter family member 1B1transporter
OpicaponeATP-dependent translocase ABCB1transporter
OpicaponeBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
OpicaponeSolute carrier organic anion transporter family member 1B3transporter
OpicaponeSolute carrier organic anion transporter family member 2B1transporter
OpicaponeCytochrome P450 2C9enzyme
OpicaponeCytochrome P450 1A2enzyme
OpicaponeCytochrome P450 2B6enzyme
MidostaurinProtein kinase C alpha typetarget
MidostaurinVascular endothelial growth factor receptor 2target
MidostaurinMast/stem cell growth factor receptor Kittarget
MidostaurinPlatelet-derived growth factor receptor alphatarget
MidostaurinPlatelet-derived growth factor receptor betatarget
MidostaurinReceptor-type tyrosine-protein kinase FLT3target
MidostaurinCytochrome P450 3A Subfamilyenzyme
MidostaurinCytochrome P450 1A2enzyme
MidostaurinCytochrome P450 2B6enzyme
MidostaurinCytochrome P450 2C8enzyme
MidostaurinCytochrome P450 2C9enzyme
MidostaurinCytochrome P450 2C19enzyme
MidostaurinCytochrome P450 2D6enzyme
MidostaurinCytochrome P450 2E1enzyme
MidostaurinCytochrome P450 3A4enzyme
MidostaurinCytochrome P450 3A5enzyme
MidostaurinCytochrome P450 3A7enzyme
MidostaurinCytochrome P450 3A43enzyme
MidostaurinProtein kinase C gamma typetarget
St. John's WortATP-dependent translocase ABCB1transporter
St. John's WortCytochrome P450 3A4enzyme
St. John's WortCytochrome P450 2D6enzyme
St. John's WortCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2B6enzyme
EfavirenzCytochrome P450 3A4enzyme
EfavirenzCytochrome P450 2C19enzyme
EfavirenzCytochrome P450 2C9enzyme
EfavirenzCytochrome P450 1A2enzyme
EfavirenzCytochrome P450 2D6enzyme
EfavirenzReverse transcriptase/RNaseHtarget
EfavirenzCytochrome P450 2C8enzyme
EfavirenzAlbumincarrier
EfavirenzCytochrome P450 3A5enzyme
EfavirenzCytochrome P450 3A7enzyme
EfavirenzUDP-glucuronosyltransferase 1A1enzyme
EfavirenzBile salt export pumptransporter
EfavirenzSolute carrier family 22 member 1transporter
EfavirenzGag-Pol polyproteintarget
NelfinavirHIV-1 proteasetarget
NelfinavirCytochrome P450 2C19enzyme
NelfinavirCytochrome P450 3A4enzyme
NelfinavirCytochrome P450 2B6enzyme
NelfinavirCytochrome P450 3A5enzyme
NelfinavirCytochrome P450 3A7enzyme
NelfinavirATP-dependent translocase ABCB1transporter
NelfinavirSolute carrier family 22 member 1transporter
NelfinavirSolute carrier organic anion transporter family member 1A2transporter
NelfinavirBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
NelfinavirSolute carrier organic anion transporter family member 1B1transporter
NelfinavirCytochrome P450 2D6enzyme
NelfinavirAlbumincarrier
NelfinavirUDP-glucuronosyltransferase 1A1enzyme
NelfinavirSolute carrier organic anion transporter family member 1B3transporter
NelfinavirSolute carrier organic anion transporter family member 2B1transporter
NelfinavirBile salt export pumptransporter
NelfinavirCytochrome P450 2C9enzyme
NelfinavirAlpha-1-acid glycoprotein 1carrier
NorethisteroneProgesterone receptortarget
NorethisteroneATP-dependent translocase ABCB1transporter
NorethisteroneCytochrome P450 2C19enzyme
NorethisteroneAlbumincarrier
NorethisteroneSex hormone-binding globulincarrier
NorethisteroneAldo-keto reductase family 1 member C4enzyme
Norethisterone3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
Norethisterone3-oxo-5-alpha-steroid 4-dehydrogenaseenzyme
NorethisteroneAldo-keto reductase family 1 member D1enzyme
NorethisteroneCytochrome P450 3A4enzyme
NorethisteroneCytochrome P450 1A2enzyme
NorethisteroneCytochrome P450 2A6enzyme
NorethisteroneGlucocorticoid receptortarget
NorethisteroneAndrogen receptortarget
HydrocortisoneAnnexin A1target
HydrocortisoneGlucocorticoid receptortarget
HydrocortisoneSex hormone-binding globulincarrier
HydrocortisoneCytochrome P450 3A4enzyme
HydrocortisoneCytochrome P450 3A5enzyme
HydrocortisoneCytochrome P450 3A7enzyme
HydrocortisoneATP-dependent translocase ABCB1transporter
HydrocortisoneSolute carrier organic anion transporter family member 1A2transporter
HydrocortisoneCytochrome P450 11B1, mitochondrialenzyme
HydrocortisoneCytochrome P450 11B2, mitochondrialenzyme
HydrocortisoneCytochrome P450 2C8enzyme
HydrocortisoneCorticosteroid-binding globulincarrier
HydrocortisoneOrganic anion transporter 3transporter
HydrocortisoneAldo-keto reductase family 1 member D1enzyme
Hydrocortisone3-oxo-5-alpha-steroid 4-dehydrogenase 2enzyme
Hydrocortisone11-beta-hydroxysteroid dehydrogenase type 2enzyme
Hydrocortisone11-beta-hydroxysteroid dehydrogenase 1enzyme
HydrocortisoneCytochrome P450 2A6enzyme
HydrocortisoneCytochrome P450 1B1enzyme
HydrocortisoneCytochrome P450 2B6enzyme
HydrocortisoneCytochrome P450 2C9enzyme
HydrocortisoneCytochrome P450 2C19enzyme
BudesonideGlucocorticoid receptortarget
BudesonideCytochrome P450 3A4enzyme
BudesonideCytochrome P450 3A5enzyme
BudesonideBile salt export pumptransporter
BudesonideATP-dependent translocase ABCB1transporter
BudesonideAnnexin A1target
BudesonideCytochrome P450 3A Subfamilyenzyme
BudesonideCytochrome P450 2A6enzyme
BudesonideCytochrome P450 1B1enzyme
BudesonideCytochrome P450 2B6enzyme
BudesonideCytochrome P450 2C8enzyme
BudesonideCytochrome P450 2C9enzyme
BudesonideCytochrome P450 2C19enzyme
BudesonideCorticosteroid-binding globulincarrier
BudesonideSolute carrier organic anion transporter family member 1A2transporter
BudesonideOrganic anion transporter 3transporter
BudesonideAlbumincarrier
MethylprednisoloneGlucocorticoid receptortarget
MethylprednisoloneCytochrome P450 3A4enzyme
MethylprednisoloneATP-dependent translocase ABCB1transporter
MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
MethylprednisoloneCytochrome P450 2A6enzyme
MethylprednisoloneCytochrome P450 1B1enzyme
MethylprednisoloneCytochrome P450 2B6enzyme
MethylprednisoloneCytochrome P450 2C8enzyme
MethylprednisoloneCytochrome P450 2C9enzyme
MethylprednisoloneCytochrome P450 2C19enzyme
MethylprednisoloneAnnexin A1target
Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
MethylprednisoloneAlbumincarrier
BetamethasoneGlucocorticoid receptortarget
BetamethasoneCytochrome P450 3A4enzyme
BetamethasoneATP-dependent translocase ABCB1transporter
BetamethasoneAromataseenzyme
BetamethasoneCytochrome P450 3A5enzyme
BetamethasoneCytochrome P450 3A7enzyme
BetamethasoneCytochrome P450 2A6enzyme
BetamethasoneCytochrome P450 1B1enzyme
BetamethasoneCytochrome P450 2B6enzyme
BetamethasoneCytochrome P450 2C8enzyme
BetamethasoneCytochrome P450 2C9enzyme
BetamethasoneCytochrome P450 2C19enzyme
BetamethasoneAlbumincarrier
BetamethasoneCorticosteroid-binding globulincarrier
Prednisolone phosphateCytochrome P450 3A4enzyme
Prednisolone phosphateCytochrome P450 3A5enzyme
Prednisolone phosphateCytochrome P450 3A Subfamilyenzyme
Prednisolone phosphateCytochrome P450 2A6enzyme
Prednisolone phosphateCytochrome P450 1B1enzyme
Prednisolone phosphateCytochrome P450 2B6enzyme
Prednisolone phosphateCytochrome P450 2C8enzyme
Prednisolone phosphateCytochrome P450 2C9enzyme
Prednisolone phosphateCytochrome P450 2C19enzyme
Prednisolone phosphate11-beta-hydroxysteroid dehydrogenase type 2enzyme
Prednisolone phosphate11-beta-hydroxysteroid dehydrogenase 1enzyme
Prednisolone phosphateGlucocorticoid receptortarget
Prednisolone phosphateAnnexin A1target
Prednisolone phosphateSolute carrier organic anion transporter family member 1A2transporter
Prednisolone phosphateATP-dependent translocase ABCB1transporter
Prednisolone phosphateOrganic anion transporter 3transporter
Prednisolone phosphateCorticosteroid-binding globulincarrier
Prednisolone phosphateAlbumincarrier
Dexamethasone acetateGlucocorticoid receptortarget
Dexamethasone acetateAnnexin A1target
Dexamethasone acetateNitric oxide synthase, inducibletarget
Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
Dexamethasone acetateCytochrome P450 3A4enzyme
Dexamethasone acetateCytochrome P450 3A5enzyme
Dexamethasone acetateCytochrome P450 3A7enzyme
Dexamethasone acetateBile salt export pumptransporter
Dexamethasone acetateATP-dependent translocase ABCB1transporter
Dexamethasone acetateATP-binding cassette sub-family C member 2transporter
Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
Dexamethasone acetateBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
Dexamethasone acetateCytochrome P450 1A1enzyme
Dexamethasone acetateCytochrome P450 2A6enzyme
Dexamethasone acetateCytochrome P450 2B6enzyme
Dexamethasone acetateCytochrome P450 2C19enzyme
Dexamethasone acetateCytochrome P450 2C8enzyme
Dexamethasone acetateCytochrome P450 2E1enzyme
Dexamethasone acetateCytochrome P450 3A43enzyme
Dexamethasone acetateCytochrome P450 4A11enzyme
Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
Dexamethasone acetateAlbumincarrier
Dexamethasone acetate11-beta-hydroxysteroid dehydrogenase type 2enzyme
Dexamethasone acetate11-beta-hydroxysteroid dehydrogenase 1enzyme
Dexamethasone acetateOrganic anion transporter 3transporter
DabrafenibCytochrome P450 3A4enzyme
DabrafenibCytochrome P450 2C8enzyme
DabrafenibATP-dependent translocase ABCB1transporter
DabrafenibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DabrafenibSolute carrier organic anion transporter family member 1B1transporter
DabrafenibSolute carrier organic anion transporter family member 1B3transporter
DabrafenibSolute carrier family 22 member 6transporter
DabrafenibOrganic anion transporter 3transporter
DabrafenibSerine/threonine-protein kinase B-raftarget
DabrafenibRAF proto-oncogene serine/threonine-protein kinasetarget
DabrafenibSerine/threonine-protein kinase SIK1target
DabrafenibSerine/threonine-protein kinase Nek11target
DabrafenibLIM domain kinase 1target
DabrafenibCytochrome P450 2B6enzyme
DabrafenibCytochrome P450 2C9enzyme
DabrafenibCytochrome P450 2C19enzyme
DabrafenibCytochrome P450 1A2enzyme
DabrafenibAlbumincarrier
DabrafenibSolute carrier organic anion transporter family member 1A2transporter
DabrafenibSolute carrier family 22 member 2transporter
DabrafenibUDP-glucuronosyltransferase 1A1enzyme
MitapivatCytochrome P450 3A4enzyme
MitapivatCytochrome P450 2B6enzyme
MitapivatCytochrome P450 2C8enzyme
MitapivatCytochrome P450 2C9enzyme
MitapivatCytochrome P450 2C19enzyme
MitapivatUDP-glucuronosyltransferase 1A1enzyme
MitapivatATP-dependent translocase ABCB1transporter
MitapivatCytochrome P450 1A2enzyme
MitapivatPyruvate kinase PKLRtarget
MitapivatAromatasetarget
MavacamtenCytochrome P450 2C19enzyme
MavacamtenCytochrome P450 3A4enzyme
MavacamtenCytochrome P450 2C9enzyme
MavacamtenCytochrome P450 2B6enzyme
MavacamtenMyosin-7target
MavacamtenCytochrome P450 3A5enzyme
MavacamtenCytochrome P450 2C8enzyme
MavacamtenCytochrome P450 2D6enzyme
PirtobrutinibCytochrome P450 3A4enzyme
PirtobrutinibUDP-glucuronosyltransferase 1A8enzyme
PirtobrutinibUDP-glucuronosyltransferase 1A9enzyme
PirtobrutinibCytochrome P450 2C8enzyme
PirtobrutinibCytochrome P450 2C9enzyme
PirtobrutinibCytochrome P450 1A2enzyme
PirtobrutinibCytochrome P450 2B6enzyme
PirtobrutinibCytochrome P450 2C19enzyme
PirtobrutinibCytochrome P450 2D6enzyme
PirtobrutinibCytochrome P450 3A5enzyme
PirtobrutinibTyrosine-protein kinase BTKtarget
PirtobrutinibATP-dependent translocase ABCB1transporter
PirtobrutinibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
SparsentanEndothelin-1 receptortarget
SparsentanType-2 angiotensin II receptortarget
SparsentanCytochrome P450 3A4enzyme
SparsentanCytochrome P450 2B6enzyme
SparsentanCytochrome P450 2C9enzyme
SparsentanCytochrome P450 2C19enzyme
SparsentanATP-dependent translocase ABCB1transporter
SparsentanBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
SparsentanSolute carrier organic anion transporter family member 1B3transporter
SparsentanOrganic anion transporter 3transporter
SparsentanType-1 angiotensin II receptortarget
LetermovirUDP-glucuronosyltransferase 1A1enzyme
LetermovirUDP-glucuronosyltransferase 1A3enzyme
LetermovirSolute carrier organic anion transporter family member 1B1transporter
LetermovirSolute carrier organic anion transporter family member 1B3transporter
LetermovirCytochrome P450 2D6enzyme
LetermovirCytochrome P450 2C8enzyme
LetermovirCytochrome P450 2C19enzyme
LetermovirCytochrome P450 2C9enzyme
LetermovirCytochrome P450 2B6enzyme
LetermovirATP-dependent translocase ABCB1transporter
LetermovirBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
LetermovirBile salt export pumptransporter
LetermovirOrganic anion transporter 3transporter
LetermovirATP-binding cassette sub-family C member 2transporter
LetermovirCMV DNA Terminase Complextarget
LetermovirCytochrome P450 3A Subfamilyenzyme
RepotrectinibProto-oncogene tyrosine-protein kinase ROStarget
RepotrectinibHigh affinity nerve growth factor receptortarget
RepotrectinibBDNF/NT-3 growth factors receptortarget
RepotrectinibNT-3 growth factor receptortarget
RepotrectinibCytochrome P450 3A4enzyme
RepotrectinibATP-dependent translocase ABCB1transporter
RepotrectinibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
RepotrectinibSolute carrier organic anion transporter family member 1B1transporter
RepotrectinibMultidrug and toxin extrusion protein 2transporter
RepotrectinibCytochrome P450 2B6enzyme
RepotrectinibCytochrome P450 2C8enzyme
RepotrectinibCytochrome P450 2C19enzyme
RepotrectinibCytochrome P450 2C9enzyme
RepotrectinibCytochrome P450 3A5enzyme
RepotrectinibUDP-glucuronosyltransferase 1A1enzyme
NirogacestatPresenilin-1target
NirogacestatCytochrome P450 3A4enzyme
NirogacestatCytochrome P450 2C9enzyme
NirogacestatCytochrome P450 2C19enzyme
NirogacestatCytochrome P450 2D6enzyme
NirogacestatCytochrome P450 2B6enzyme
NirogacestatAlbumincarrier
Nirogacestatalpha1-acid glycoproteincarrier
NirogacestatATP-dependent translocase ABCB1transporter
NirogacestatCytochrome P450 2C8enzyme
NirogacestatPresenilin-2target
NirogacestatGamma-secretase subunit APH-1Atarget
NirogacestatGamma-secretase subunit PEN-2target
TovorafenibCytochrome P450 2C8enzyme
TovorafenibCytochrome P450 3A4enzyme
TovorafenibCytochrome P450 2C9enzyme
TovorafenibCytochrome P450 2C19enzyme
TovorafenibCytochrome P450 1A2enzyme
TovorafenibCytochrome P450 2B6enzyme
TovorafenibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
TovorafenibRAF proto-oncogene serine/threonine-protein kinasetarget
TovorafenibSerine/threonine-protein kinase B-raftarget
TovorafenibSerine/threonine-protein kinase A-Raftarget
VorasidenibCytochrome P450 1A2enzyme
VorasidenibCytochrome P450 2B6enzyme
VorasidenibCytochrome P450 2C8enzyme
VorasidenibCytochrome P450 2C9enzyme
VorasidenibCytochrome P450 2C19enzyme
VorasidenibCytochrome P450 2D6enzyme
VorasidenibCytochrome P450 3A4enzyme
VorasidenibUDP-glucuronosyltransferase 1A4enzyme
VorasidenibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
VorasidenibIsocitrate dehydrogenase [NADP] cytoplasmictarget
VorasidenibIsocitrate dehydrogenase [NADP], mitochondrialtarget
VorasidenibIsocitrate dehydrogenase [NAD] subunit alpha, mitochondrialtarget
VorasidenibIsocitrate dehydrogenase [NAD] subunit beta, mitochondrialtarget
VorasidenibIsocitrate dehydrogenase [NAD] subunit gamma, mitochondrialtarget