Stage IV Pancreatic Cancer (DBCOND0028776)

Identifiers

Synonyms
Pancreatic Cancer Stage IV

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03697564
Nivolumab + Cabiralizumab + Gemcitabine in Patients With Stage IV Pancreatic Cancer Achieving Disease Control in Response to First-line Chemotherapy (GemCaN Trial).treatment2suspended
NCT06017284
Thalidomide to Chemotherapy Related Nausea and Vomiting in Pancreatic Cancertreatment3recruiting
NCT03236883
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation in the Treatment of Pancreatic Cancertreatment1unknown_status
NCT04150042
SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cellstreatment1recruiting
NCT03412799
Study of SBP-101 Combined With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancertreatment1completed
NCT05642962
Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)treatment1 / 2recruiting
NCT06518538
Evaluate Efficacy of Devimistat in Combination With mFFX in 2nd Line Patients With Metastatic Pancreatic Cancertreatment2withdrawn
NCT04181645
SHR- 1210 Combined With Paclitaxel (Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic CancertreatmentNot Availablecompleted
NCT05254171
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancertreatment2 / 3recruiting
NCT04674956
A Prospective, Randomized, Double-blinded, Multi-center Clinical Trial to Evaluate the Efficiency and Safety of Anti-PD1 Antibody (Camrelizumab) Combined With Paclitaxel(Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancertreatment3recruiting
NCT04628806
Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor CellsNo drug interventionsNot AvailableNot Availableunknown_status
NCT02981641
IORT Versus CCRT for Pancreatic CancerNo drug interventionstreatmentNot Availableunknown_status
NCT04137822
Expanded Access Program Using IMM-101 for Patients With Advanced Pancreatic CancerNot AvailableNot Availableno_longer_available
NCT04406831
The Role of MicroRNA in the Diagnosis, Prognosis and Response to Treatment in Pancreatic CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04953962
Study of CBP501/Cisplatin/Nivolumab Combinations in Advanced Pancreatic Cancertreatment2completed
NCT04852367
PanDox: Targeted Doxorubicin in Pancreatic Tumoursbasic_science1withdrawn
NCT03252808
Phase I Study of TBI-1401(HF10) Plus Chemotherapy in Patients With Unresectable Pancreatic Cancer.treatment1active_not_recruiting
NCT03087591
APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by SurgeryNo drug interventionstreatment1completed
NCT01453153
Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancertreatment1 / 2completed
NCT00075647
CCI-779 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancertreatment2completed
NCT01233505
Veliparib, Oxaliplatin, and Capecitabine in Treating Patients With Advanced Solid Tumorstreatment1terminated
NCT01647828
A Phase 1b/2 Study of OMP-59R5 (Tarextumab) in Combination With Nab-Paclitaxel and Gemcitabine in Subjects With Previously Untreated Stage IV Pancreatic Cancertreatment1 / 2completed
NCT00416793
Bortezomib and Carboplatin in Treating Patients With Metastatic Pancreatic Cancertreatment2terminated
NCT00085371
Triapine as First-Line or Second-Line Therapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreastreatment2completed
NCT00047307
Flavopiridol Plus Radiation Therapy Followed By Gemcitabine Hydrochloride in Treating Patients With Locally Advanced, Unresectable Pancreatic Cancertreatment1completed
NCT01537107
Sirolimus and Vismodegib in Treating Patients With Solid Tumors or Pancreatic Cancer That is Metastatic or Cannot Be Removed By Surgerytreatment1completed
NCT02896907
Ascorbic Acid and Combination Chemotherapy in Treating Patients With Locally Advanced or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgerytreatment0completed
NCT01145456
Gamma-Secretase Inhibitor RO4929097 and Gemcitabine Hydrochloride in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT01488552
Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancertreatment1 / 2completed
NCT02414100
Patient Derived Cancer Cell Lines in Identifying Molecular Changes in Patients With Previously Untreated Pancreatic Cancer Receiving Gemcitabine Hydrochloride-Based ChemotherapyNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01806675
18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapydiagnostic1 / 2completed
NCT04267575
Canady Helios Cold Plasma Scalpel Treatment at the Surgical Margin and Macroscopic Tumor SitesNo drug interventionstreatmentNot Availableunknown_status
NCT00735917
Saracatinib in Treating Patients With Previously Treated Metastatic Pancreatic Cancertreatment2completed
NCT00028834
Bevacizumab and Gemcitabine in Treating Patients With Advanced Pancreatic Cancertreatment2completed
NCT01131234
Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT00028496
Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancertreatment1completed
NCT02495896
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumorstreatment1terminated
NCT03222258
Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03368963
TAS102 in Combination With NAL-IRI in Advanced GI Cancerstreatment1 / 2recruiting
NCT01064622
Gemcitabine Hydrochloride With or Without Vismodegib in Treating Patients With Recurrent or Metastatic Pancreatic Cancertreatment1 / 2completed
NCT04377048
Nivolumab Adding on Gemcitabine/S-1 in Metastatic Pancreatic Cancertreatment2unknown_status
NCT00091026
Bevacizumab and Gemcitabine Combined With Either Cetuximab or Erlotinib in Treating Patients With Advanced Pancreatic Cancertreatment2completed
NCT00095966
Sorafenib and Gemcitabine in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancertreatment2completed
NCT01846520
Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung CancersNo drug interventionssupportive_careNot Availablecompleted
NCT00003531
Antineoplaston Therapy in Treating Patients With Stage IV Pancreatic Cancertreatment2terminated
NCT00383760
Eribulin Mesylate as Second-Line Therapy for Locally Advanced, Unresectable, or Metastatic Pancreatic Cancer Patientstreatment2completed
NCT00031694
Paclitaxel and Bryostatin 1 in Treating Patients With Advanced Pancreatic Cancertreatment2completed
NCT01893294
Gemcitabine Hydrochloride in Treating Patients With Locally Advanced Pancreatic Cancertreatment1completed
NCT01232829
Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas Cancertreatment2completed
NCT01555489
Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Catreatment2terminated
NCT05088889
Maintenance Ipilimumab + Nivolumab Post Induction Chemotherapy + SBRT for First Line Treatment Stage IV Pancreatic Cancertreatment1recruiting
NCT03825289
Trametinib and Hydroxychloroquine in Treating Patients With Pancreatic Cancertreatment1recruiting
NCT01473940
Ipilimumab and Gemcitabine Hydrochloride in Treating Patients With Stage III-IV or Recurrent Pancreatic Cancer That Cannot Be Removed by Surgerytreatment1completed
NCT02227940
Ceritinib and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors or Locally Advanced or Metastatic Pancreatic Cancertreatment1completed
NCT03095781
Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancertreatment1completed
NCT00031681
7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)treatment1completed
NCT01839981
CPI-613 in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancertreatment1completed
NCT02166255
APN401 in Treating Patients With Melanoma, Kidney Cancer, Pancreatic Cancer, or Other Solid Tumors That Are Metastatic or Cannot Be Removed By SurgeryNo drug interventionstreatment1completed
NCT02575508
Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancertreatment1 / 2withdrawn
NCT02048943
Dovitinib Lactate, Gemcitabine Hydrochloride, and Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Solid Tumors or Pancreatic Cancertreatment1withdrawn
NCT00039403
UCN-01 and Gemcitabine in Treating Patients With Unresectable or Metastatic Pancreatic Cancertreatment1completed
NCT03154190
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerNo drug interventionshealth_services_researchNot Availableunknown_status
NCT05240690
Umbilical Cord Blood Derived MAK Immune Cells Combined With Standard Second-Line Treatments for Hepatobiliary and Pancreatic MalignanciesNo drug interventionstreatment1not_yet_recruiting
NCT01191684
Vaccine Therapy in Treating Patients With Colorectal, Stomach, or Pancreatic Cancertreatment1completed
NCT00397384
Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancertreatment1completed
NCT00397787
Sunitinib in Treating Patients With Metastatic Pancreatic Cancer That Progressed After First-Line Therapy With Gemcitabinetreatment2completed
NCT01282333
Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancertreatment1terminated
NCT00462553
Sunitinib and Gemcitabine in Treating Patients With Pancreatic Cancer or Other Solid Tumorstreatment1completed
NCT00030498
Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunctiontreatment1completed
NCT01741597
Dynamic Contrast Enhanced MRI in Patients With Advanced Breast or Pancreatic Cancer With Metastases to the Liver or Lungdiagnostic1withdrawn
NCT01927393
Palliative Care in Improving Quality of Life and Symptoms in Patients With Stage III-IV Pancreatic or Ovarian CancerNo drug interventionssupportive_careNot Availablewithdrawn
NCT02050178
Dose Escalation Study of OMP-54F28 in Combination With Nab-Paclitaxel and Gemcitabine in Patients With Previously Untreated Stage IV Pancreatic Cancertreatment1completed
NCT02333188
Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal Cancertreatment1completed
NCT01195415
Vismodegib and Gemcitabine Hydrochloride in Treating Patients With Advanced Pancreatic Cancertreatment2completed
NCT02005315
A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancertreatment1completed
NCT01534637
Aprepitant in Preventing Nausea and Vomiting in Patients Undergoing Chemotherapy and Radiation Therapy for Pancreatic Cancersupportive_care2completed
NCT01643499
Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignanciestreatment1completed
NCT02178436
Gemcitabine, Nab-paclitaxel and KPT-330 in Advanced Pancreatic Cancertreatment1 / 2completed
NCT01227018
PhII Study STA-9090 as Second or Third-Line Therapy for Metastatic Pancreas Cancertreatment2terminated
NCT01835041
CPI-613 and Combination Chemotherapy in Treating Patients With Metastatic Pancreatic Cancertreatment1completed
NCT01280058
Carboplatin and Paclitaxel With or Without Viral Therapy in Treating Patients With Recurrent or Metastatic Pancreatic Cancertreatment2completed
NCT02307539
Palliative Care in Improving Quality of Life in Patients With Newly Diagnosed Pancreatic CancerNo drug interventionssupportive_careNot Availablecompleted
NCT01666730
Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancertreatment2completed
NCT00101348
Erlotinib and Cetuximab With or Without Bevacizumab in Treating Patients With Metastatic or Unresectable Kidney, Colorectal, Head and Neck, Pancreatic, or Non-Small Cell Lung Cancertreatment1 / 2completed
NCT02620865
BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancertreatment1 / 2completed
NCT00004074
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neutreatment1completed
NCT05631574
Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal CancerNo drug interventionstreatment1recruiting
NCT01851174
Study to Evaluate Bi-weekly Dosing of Gemcitabine Plus Nab-Paclitaxel to Treat Metastatic Pancreatic Cancertreatment2terminated
NCT00331682
Docetaxel and Flavopiridol in Treating Patients With Refractory Metastatic Pancreatic Cancertreatment2completed
NCT01525082
Capecitabine, Temozolomide, and Bevacizumab for Metastatic or Unresectable Pancreatic Neuroendocrine Tumorstreatment2completed
NCT01924260
Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic Cancertreatment1completed
NCT00088894
Gemcitabine With or Without Bevacizumab in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancertreatment3completed
NCT00087191
EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerdiagnosticNot Availableterminated
NCT00981162
Sorafenib Tosylate and Everolimus in Treating Patients With Advanced Solid Tumors and Metastatic Pancreatic Cancer That Does Not Respond to Gemcitabine Hydrochloridetreatment1completed
NCT01486329
VXM01 Phase I Dose Escalation Study in Patients With Locally Advanced, Inoperable and Stage IV Pancreatic Cancertreatment1completed
NCT01222689
Selumetinib and Erlotinib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancertreatment2completed
NCT00052689
Bortezomib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancertreatment2completed
NCT00577889
Gemcitabine Hydrochloride and Tanespimycin in Treating Patients With Stage IV Pancreatic Cancertreatment2completed
NCT03682289
Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumorstreatment2recruiting
NCT01497392
Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancerstreatment1completed
NCT00114244
Sorafenib With or Without Gemcitabine in Treating Patients With Metastatic Pancreatic Cancertreatment2completed
NCT01893801
Nab-Pac+Cis+Gem in Pts w Previously Untreated Metastatic PDAtreatment1 / 2completed
NCT00474812
Dasatinib in Treating Patients With Metastatic Pancreatic Cancertreatment2completed
NCT00617708
S0727 Gemcitabine Hydrochloride and Erlotinib Hydrochloride With or Without Monoclonal Antibody Therapy in Treating Patients With Metastatic Pancreatic Cancer That Cannot Be Removed By Surgerytreatment1 / 2completed
NCT01658943
Selumetinib and Akt Inhibitor MK2206 or mFOLFOX Therapy Comprising Oxaliplatin and Fluorouracil in Treating Patients With Metastatic Pancreatic Cancer Previously Treated With Chemotherapytreatment2completed