| Interleukin-18 | Humans | Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natura... more | 3 | Details |
| Interleukin-18 receptor 1 | Humans | Within the IL18 receptor complex, responsible for the binding of the pro-inflammatory cytokine IL18, but not IL1A nor... more | 1 | Details |
| Interleukin-2 | Humans | Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and ... more | 20 | Details |
| Interleukin-2 receptor | Humans | Not Available | 8 | Details |
| Interleukin-2 receptor subunit alpha | Humans | Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory ... more | 10 | Details |
| Interleukin-2 receptor subunit beta | Humans | Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogen... more | 11 | Details |
| Interleukin-20 | Humans | Pro-inflammatory and angiogenic cytokine mainly secreted by monocytes and skin keratinocytes that plays crucial roles... more | 1 | Details |
| Interleukin-21 | Humans | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the... more | 2 | Details |
| Interleukin-21 receptor | Humans | This is a receptor for interleukin-21 | 1 | Details |
| Interleukin-22 | Humans | Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in th... more | 1 | Details |
| Interleukin-22 receptor subunit alpha-1 | Humans | Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling I... more | 2 | Details |
| Interleukin-23 | Humans | Not Available | 4 | Details |
| Interleukin-23 receptor | Humans | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly c... more | 1 | Details |
| Interleukin-23 subunit alpha | Humans | Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive i... more | 6 | Details |
| Interleukin-27 subunit alpha | Humans | Associates with EBI3 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-2... more | 1 | Details |
| Interleukin-3 | Humans | Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls... more | 6 | Details |
| Interleukin-3 receptor subunit alpha | Humans | Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls ... more | 11 | Details |
| Interleukin-31 receptor subunit alpha | Humans | Functions as a membrane-bound signal-transducing subunit of the IL31 receptor complex (heterodimer composed of OSMR a... more | 1 | Details |
| Interleukin-33 | Humans | Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signal... more | 5 | Details |
| Interleukin-36 alpha | Humans | Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK sig... more | 1 | Details |
| Interleukin-37 | Humans | Immune regulatory cytokine that acts as a suppressor of innate inflammatory and immune responses involved in curbing ... more | 2 | Details |
| Interleukin-4 | Humans | Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibo... more | 5 | Details |
| Interleukin-4 receptor subunit alpha | Humans | Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involv... more | 6 | Details |
| Interleukin-5 | Humans | Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the surviv... more | 5 | Details |
| Interleukin-5 receptor subunit alpha | Humans | Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. A... more | 2 | Details |