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Displaying targets 3051 - 3075 of 6103 in total
TargetOrganismDescription# of Drugs
Iron(3+)-hydroxamate-binding protein FhuDEscherichia coli (strain K12)Part of the ABC transporter complex FhuCDB involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate co...  more5Details
Iron-dependent extradiol dioxygenaseMycobacterium tuberculosisCatalyzes the meta-cleavage of 3,4-dihydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione (3,4-DHSA) to produce 4,5-...  more1Details
Islet amyloid polypeptideHumansAmylin/IAPP is a glucoregulatory peptide hormone that plays an important role in the regulation of energy homeostasis...  more3Details
Isoaspartyl dipeptidaseEscherichia coli (strain K12)Catalyzes the hydrolytic cleavage of a subset of L-isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins...  more2Details
Isoaspartyl peptidase/L-asparaginaseHumansHas both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which...  more3Details
Isobutyryl-CoA dehydrogenase, mitochondrialHumansIsobutyryl-CoA dehydrogenase which catalyzes the conversion of 2-methylpropanoyl-CoA to (2E)-2-methylpropenoyl-CoA in...  more2Details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialHumansCatalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The...  more6Details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialHumansPlays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarbox...  more3Details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialHumansRegulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of is...  more4Details
Isocitrate dehydrogenase [NADP]Azotobacter vinelandiiNot Available2Details
Isocitrate dehydrogenase [NADP]Escherichia coli (strain K12)Not Available4Details
Isocitrate dehydrogenase [NADP]Bacillus subtilis (strain 168)Not Available4Details
Isocitrate dehydrogenase [NADP] cytoplasmicHumansCatalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-ox...  more10Details
Isocitrate dehydrogenase [NADP], mitochondrialHumansPlays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate...  more5Details
Isocitrate lyaseMycobacterium tuberculosisInvolved in the persistence and virulence of M.tuberculosis. Catalyzes the reversible formation of succinate and glyo...  more1Details
Isoleucine--tRNA ligaseStaphylococcus aureusCatalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally ...  more1Details
Isoleucine--tRNA ligaseThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally ...  more1Details
Isoleucine--tRNA ligase, cytoplasmicHumansCatalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is f...  more1Details
Isoleucine--tRNA ligase, mitochondrialHumansAminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile))1Details
Isoleucine--tRNA ligase, putativePlasmodium falciparum (isolate 3D7)Not Available1Details
Isopentenyl-diphosphate Delta-isomeraseEscherichia coli (strain K12)Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic al...  more5Details
Isopentenyl-diphosphate delta-isomeraseThermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate iso...  more1Details
Isopentenyl-diphosphate delta-isomeraseBacillus subtilis (strain 168)Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate iso...  more1Details
Isopentenyl-diphosphate Delta-isomerase 1HumansCatalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic al...  more1Details
Isovaleryl-CoA dehydrogenase, mitochondrialHumansA mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism, where isovaleryl-CoA (3-methylbuta...  more2Details
Displaying targets 3051 - 3075 of 6103 in total