| Interleukin-1 receptor type 2 | Humans | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive b... more | 1 | Details |
| Interleukin-1 receptor-associated kinase 1 | Humans | Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign patho... more | 4 | Details |
| Interleukin-1 receptor-associated kinase 3 | Humans | Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-lik... more | 1 | Details |
| Interleukin-1 receptor-associated kinase 4 | Humans | Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign patho... more | 7 | Details |
| Interleukin-1 receptor-like 1 | Humans | Receptor for interleukin-33 (IL-33) which plays crucial roles in innate and adaptive immunity, contributing to tissue... more | 3 | Details |
| Interleukin-1 receptor-like 2 | Humans | Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor ... more | 2 | Details |
| Interleukin-10 | Humans | Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory... more | 3 | Details |
| Interleukin-10 receptor subunit alpha | Humans | Cell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting ... more | 3 | Details |
| Interleukin-10 receptor subunit beta | Humans | Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1... more | 3 | Details |
| Interleukin-11 receptor subunit alpha | Humans | Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for ... more | 1 | Details |
| Interleukin-12 receptor subunit beta-1 | Humans | Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transductio... more | 5 | Details |
| Interleukin-12 receptor subunit beta-2 | Humans | Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the... more | 5 | Details |
| Interleukin-12 subunit alpha | Humans | Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primari... more | 4 | Details |
| Interleukin-12 subunit beta | Humans | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-ac... more | 6 | Details |
| Interleukin-13 | Humans | Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes wi... more | 10 | Details |
| Interleukin-13 receptor subunit alpha-2 | Humans | Cell surface receptor that plays a role in the regulation of IL-13-mediated responses. Functions as a decoy receptor ... more | 4 | Details |
| Interleukin-15 | Humans | Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial inva... more | 5 | Details |
| Interleukin-15 receptor subunit alpha | Humans | High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells pres... more | 1 | Details |
| Interleukin-17 receptor A | Humans | Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial... more | 1 | Details |
| Interleukin-17 receptor B | Humans | Receptor for the pro-inflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differe... more | 1 | Details |
| Interleukin-17 receptor C | Humans | Receptor for IL17A and IL17F, major effector cytokines of innate and adaptive immune system involved in antimicrobial... more | 1 | Details |
| Interleukin-17 receptor D | Humans | Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. Regulates the nuclear ... more | 1 | Details |
| Interleukin-17 receptor E | Humans | Specific functional receptor for IL17C. May be signaling through the NF-kappa-B and MAPK pathways. May require TRAF3I... more | 1 | Details |
| Interleukin-17A | Humans | Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tiss... more | 12 | Details |
| Interleukin-17F | Humans | Effector cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tiss... more | 2 | Details |