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Displaying targets 2951 - 2975 of 6103 in total
TargetOrganismDescription# of Drugs
Inter-alpha-trypsin inhibitor heavy chain H2HumansMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, incl...  more5Details
Inter-alpha-trypsin inhibitor heavy chain H3HumansMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, incl...  more4Details
Inter-alpha-trypsin inhibitor heavy chain H4HumansType II acute-phase protein (APP) involved in inflammatory responses to trauma. May also play a role in liver develop...  more4Details
Intercellular adhesion molecule 1HumansCell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-fu...  more9Details
Interferon alpha-2HumansProduced by macrophages, IFN-alpha have antiviral activities7Details
Interferon alpha-4HumansProduced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a ...  more1Details
Interferon alpha/beta receptor (IFNAR)HumansThe full receptor for Type I/II interferons comprises both receptor chains.5Details
Interferon alpha/beta receptor 1HumansTogether with IFNAR2, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, eps...  more14Details
Interferon alpha/beta receptor 2HumansTogether with IFNAR1, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, eps...  more13Details
Interferon betaHumansType I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and ot...  more4Details
Interferon gammaHumansType II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, a...  more9Details
Interferon gamma receptor 1HumansReceptor subunit for interferon gamma/INFG that plays crucial roles in antimicrobial, antiviral, and antitumor respon...  more2Details
Interferon gamma receptor 2HumansAssociates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activat...  more3Details
Interferon lambda receptor 1HumansThe IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity....  more1Details
Interferon-induced, double-stranded RNA-activated protein kinaseHumansIFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic trans...  more4Details
Interferon-inducible GTPase 5HumansGTPase required for sperm motility and therefore male fertility, via positive regulation of spermatozoa fibrous sheat...  more2Details
Interferon-inducible protein AIM2HumansSensor component of the AIM2 inflammasome, which mediates inflammasome activation in response to the presence of doub...  more1Details
Interferon-stimulated gene 20 kDa proteinHumansInterferon-induced antiviral exoribonuclease that acts mainly on single-stranded RNA. Exhibits antiviral activity aga...  more1Details
Interleukin enhancer-binding factor 3HumansRNA-binding protein that plays an essential role in the biogenesis of circular RNAs (circRNAs) which are produced by ...  more1Details
Interleukin-1HumansThis represents the interleukin-1 protein.2Details
Interleukin-1 alphaHumansCytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important...  more5Details
Interleukin-1 betaHumansPotent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthes...  more21Details
Interleukin-1 receptor accessory proteinHumansCoreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates w...  more1Details
Interleukin-1 receptor antagonist proteinHumansAnti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and ...  more1Details
Interleukin-1 receptor type 1HumansReceptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the h...  more6Details
Displaying targets 2951 - 2975 of 6103 in total