Boron Compounds

Name
Boron Compounds
Accession Number
DBCAT000461
Description

Inorganic or organic compounds that contain boron as an integral part of the molecule.

Drugs
DrugDrug Description
BortezomibA proteasome inhibitor used to treat multiple myeloma in patients who have not been successfully treated with at least two previous therapies.
Phenylethane Boronic AcidNot Available
3-Nitrophenylboronic AcidNot Available
AN0128Investigated for use/treatment in acne, atopic dermatitis, pediatric indications, and psoriasis and psoriatic disorders.
FlovagatranInvestigated for use/treatment in thrombosis.
TalabostatInvestigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), lung cancer, melanoma, and pancreatic cancer.
Boric acidNo FDA- or EMA-approved therapeutic indications on its own.
DelanzomibDelanzomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, and Lymphoma, Non-Hodgkin.
VaborbactamA beta lactamase inhibitor used to treat complicated urinary tract infections.
Perboric acidIn the industry, sodium perborate is used as a disinfectant. It is also part of the ingredients for detergents, bleach powders, and personal care formulations. In cosmetic products, perboric acid...
Sodium borateNo FDA- or EMA-approved therapeutic indications on its own.
Borate ionNot Annotated
DutogliptinDutogliptin has been investigated for the treatment of Diabetes Mellitus, Type II.
Phenylboronic acidNot Available
TetrafluoroborateTetrafluoroborate is under investigation in clinical trial NCT02907073 (Positron Emission Tomography (PET) Imaging Studies With NIS Reporter).
INCB-057643INCB-057643 is under investigation in clinical trial NCT02959437 (Azacitidine Combined With Pembrolizumab and Epacadostat in Subjects With Advanced Solid Tumors (ECHO-206)).
TaniborbactamTaniborbactam is under investigation in clinical trial NCT03840148 (Safety and Efficacy Study of Cefepime/vnrx-5133 in Patients With Complicated Urinary Tract Infections).
Drugs & Drug Targets
DrugTargetType
BortezomibCytochrome P450 3A4enzyme
BortezomibCytochrome P450 2C19enzyme
BortezomibCytochrome P450 1A2enzyme
BortezomibCytochrome P450 2D6enzyme
BortezomibCytochrome P450 2C9enzyme
BortezomibProteasome subunit beta type-5target
BortezomibProteasome subunit beta type-1target
BortezomibP-glycoprotein 1transporter
BortezomibSolute carrier organic anion transporter family member 1B3transporter
Phenylethane Boronic AcidChymotrypsinogen Btarget
3-Nitrophenylboronic AcidBeta-lactamasetarget
FlovagatranProthrombintarget
VaborbactamBeta-lactamasetarget
VaborbactamCarbapenem-hydrolyzing beta-lactamase KPCtarget
VaborbactamBeta-lactamase (KPC-2)target
VaborbactamBeta-lactamase CTX-Mtarget
VaborbactamBeta-lactamase (blaSHV)target
VaborbactamBeta-lactamase SHV-1target
VaborbactamBeta-lactamase TEMtarget
VaborbactamBeta-lactamase (MIR-1)target
VaborbactamBeta-lactamasetarget
DutogliptinDipeptidyl peptidase 4target
Phenylboronic acidCocaine esterasetarget