Ophthalmic Solutions

Name
Ophthalmic Solutions
Accession Number
DBCAT001236
Description

Sterile solutions that are intended for instillation into the eye. It does not include solutions for cleaning eyeglasses or CONTACT LENS SOLUTIONS.

Drugs
DrugDrug Description
AmlexanoxUsed as a paste in the mouth to treat aphthous ulcers (canker sores).
TetryzolineAn alpha-adrenergic agonist used in the temporary symptomatic relief of discomfort and redness of the eyes due to minor irritations, as well as alleviate nasal congestion.
Hydroxyethyl celluloseAn ingredient used in formulations to alleviate irritation of the skin.
MicronomicinMicronomicin is an aminoglycoside antibiotic which is marketed in Japan, and sold under the brand names Sagamicin and Luxomicina.
Carbomer homopolymer type CA medication in artificial tears for the treatment of dry eyes.
GatifloxacinA fourth generation fluoroquinolone used to treat a wide variety of infections in the body.
LifitegrastA medication used to treat dry eye disease.
DiquafosolA medication indicated to treat dry eyes associated with keratoconjunctival disorders.
AcrizanibAcrizanib is under investigation in clinical trial NCT02355028 (LHA510 Proof-of-concept Study as a Maintenance Therapy for Patients With Wet Age-related Macular Degeneration).
LatanoprostAn isopropyl ester prodrug used to treat increased intraocular pressure.
Omidenepag isopropylAn agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure.
PerfluorohexyloctaneA drug used to treat dry eye disease.
Drugs & Drug Targets
DrugTargetType
AmlexanoxInterleukin-3target
AmlexanoxProtein S100-A12target
AmlexanoxProtein S100-A13target
AmlexanoxFibroblast growth factor 1target
AmlexanoxHeat shock protein HSP 90-alphatarget
TetryzolineAlpha-1 adrenergic receptorstarget
TetryzolineAlpha-2 adrenergic receptorstarget
TetryzolineAlpha-2C adrenergic receptortarget
GatifloxacinAlbumincarrier
GatifloxacinDNA gyrase subunit Atarget
GatifloxacinDNA gyrase subunit Btarget
GatifloxacinDNA topoisomerase 4 subunit Atarget
GatifloxacinDNA topoisomerase 4 subunit Btarget
GatifloxacinCytochrome P450 1A2enzyme
GatifloxacinDNA gyrase subunit Atarget
GatifloxacinDNA gyrase subunit Btarget
LifitegrastIntegrin alpha-Ltarget
LifitegrastCytochrome P450 2C9enzyme
LifitegrastSolute carrier organic anion transporter family member 1A2transporter
LifitegrastSolute carrier organic anion transporter family member 2B1transporter
LifitegrastIntercellular adhesion molecule 1target
DiquafosolP2Y purinoceptor 2target
LatanoprostProstaglandin F2-alpha receptortarget
LatanoprostSolute carrier organic anion transporter family member 2A1transporter
LatanoprostSolute carrier family 22 member 6transporter
LatanoprostOrganic anion transporter 3transporter
LatanoprostCorneal esterasesenzyme
Omidenepag isopropylCarboxylesteraseenzyme
Omidenepag isopropylProstaglandin E2 receptor EP2 subtypetarget
Omidenepag isopropylProstaglandin E2 receptor EP1 subtypetarget