N-substituted Glycines

Name
N-substituted Glycines
Accession Number
DBCAT001454
Description

AMINO ACIDS composed of GLYCINE substituted at the nitrogen rather than the usual carbon position, resulting in the loss of HYDROGEN BONDING donors. Polymers of these compounds are called PEPTOIDS.

Drugs
DrugDrug Description
Glycochenodeoxycholic AcidA bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed....
Glycocholic acidThe glycine conjugate of cholic acid. It acts as a detergent to solubilize fats for absorption and is itself absorbed.
GlyphosateNot Available
N,N-dimethylglycineNot Available
RacecadotrilAn anti-secretory enkephalinase inhibitor useful in the treatment of diarrhea.
SarcosineSarcosine has been investigated for the treatment of Schizophrenia.
ThiorphanA potent inhibitor of membrane metalloendopeptidase (enkephalinase). Thiorphan potentiates morphine-induced analgesia and attenuates naloxone-precipitated withdrawal symptoms.
TioproninA thiol agent indicated for the prevention of kidney stone formation in patients with severe homozygous cystinuria.
Drugs & Drug Targets
DrugTargetType
Glycochenodeoxycholic Acid7alpha-hydroxysteroid dehydrogenasetarget
Glycochenodeoxycholic AcidBile salt export pumptransporter
Glycochenodeoxycholic AcidSolute carrier organic anion transporter family member 1A2transporter
Glycochenodeoxycholic AcidIleal sodium/bile acid cotransportertransporter
Glycochenodeoxycholic AcidHepatic sodium/bile acid cotransportertransporter
Glycocholic acidGastrotropintarget
Glycocholic acidSolute carrier organic anion transporter family member 1A2transporter
Glycocholic acidSolute carrier organic anion transporter family member 1B1transporter
Glycocholic acidSolute carrier organic anion transporter family member 1B3transporter
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
GlyphosateAromatasetarget
GlyphosateAlbumincarrier
N,N-dimethylglycineMonomeric sarcosine oxidasetarget
RacecadotrilNeprilysintarget
SarcosineSodium- and chloride-dependent glycine transporter 1target
SarcosineNMDA receptortarget
SarcosineSarcosine dehydrogenase, mitochondrialenzyme
SarcosineGlycine N-methyltransferaseenzyme
SarcosineMonomeric sarcosine oxidaseenzyme
SarcosineProton-coupled amino acid transporter 1transporter
ThiorphanNeprilysintarget
TioproninMyeloperoxidaseenzyme
TioproninPeptidyl-glycine alpha-amidating monooxygenaseenzyme
TioproninMyeloperoxidasetarget
TioproninGlutathione peroxidase 1target
TioproninGlutathione peroxidasetarget
TioproninMetalloproteinasetarget
TioproninCystinetarget
TioproninSuperoxide dismutasetarget