Tuberculosis Active (DBCOND0157213)
Identifiers
- Synonyms
- Active Tuberculosis / Active tuberculosis (disorder) / Tuberculosis / Tuberculosis (disorder) / Tuberculosis NOS / Infection TBC / Infection tuberculosis / Infection caused by Mycobacterium tuberculosis (disorder) / TB / Tuberculous (qualifier value) / Tuberculous infections
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Ethionamide A second line antitubercular agent used to treat tuberculosis when other treatments have failed.Isoniazid An antibiotic used to treat mycobacterial infections; most commonly use in combination with other antimycobacterial agents for the treatment of active or latent tuberculosis.- Catalase-peroxidasetarget
- Enoyl-[acyl-carrier-protein] reductase [NADH]target
- Cytochrome P450 2E1enzyme
- Cytochrome P450 1A2enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 2D6enzyme
- Cytochrome P450 2C19enzyme
- Arylamine N-acetyltransferase 2enzyme
- Arylamine N-acetyltransferaseenzyme
- Cytochrome P450 2A6enzyme
- Cytochrome P450 2C8enzyme
- Cytochrome P450 2C8target
- Cytochrome P450 1A2target
- Cytochrome P450 3A4target
- Cytochrome P450 2C19target
- Dihydrofolate reductasetarget
- Albumincarrier
- Cytochrome P450 3A4enzyme
Morinamide A second-line pyrazine anti-tuberculosis agent.No drug targets Pyrazinamide An antituberculosis agent used as a component of tuberculosis (TB) treatment.Rifapentine An antibiotic agent used in the treatment of pulmonary tuberculosis.- DNA-directed RNA polymerase subunit beta'target
- Cytochrome P450 2C8enzyme
- Cytochrome P450 2C9enzyme
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2C19enzyme
- Cytochrome P450 2B6enzyme
- Cytochrome P450 3A Subfamilyenzyme
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT05840809 Pharmacokinetics of Drugs Used to Treat Drug Sensitive Tuberculosis in Breastfeeding Mother-infant Pairs Not Available Not Available active_not_recruiting NCT05981495 Clinical Evaluation of the NanoDetect-TB Mycobacterium Tuberculosis Detection Kit for the Diagnosis of Tuberculosis Disease No drug interventions Not Available Not Available not_yet_recruiting NCT06574529 Video-observed Therapy for Active Tuberculosis: a Feasibility Study No drug interventions other Not Available completed NCT02512484 Improving the Detection of Active Tuberculosis in Accident and Emergency Departments No drug interventions Not Available Not Available unknown_status NCT02639936 New Generation IGRA in Immunocompromised Individuals No drug interventions Not Available Not Available unknown_status NCT04048018 Performance Evaluation of the VIDAS TB-IGRA Assay. No drug interventions Not Available Not Available completed NCT06408129 COMPArison of Screening Strategies for Active TuBerculosis (COMPASS-TB) No drug interventions Not Available Not Available completed NCT01269268 Characterization and Evaluation of Diagnostic Biomarkers for Tuberculosis No drug interventions Not Available Not Available completed NCT02042261 The Role of Therapeutic Drug Monitoring in Tuberculosis - a Pilot Study No drug interventions Not Available Not Available completed NCT05045391 Pulmonary Aspergillosis in Tuberculosis Patients No drug interventions Not Available Not Available active_not_recruiting NCT03271567 Nanodisk-MS Assay for the Diagnosis of Active Pulmonary and Extrapulmonary Tuberculosis in Hospitalized Patients No drug interventions Not Available Not Available completed NCT05048381 miRNA in Sweat, a Novel Digital Biomarker for Detection of Active Tuberculosis (TB) No drug interventions Not Available Not Available withdrawn NCT02898623 Serological Test for the Diagnosis of TB No drug interventions Not Available Not Available terminated