NCT02406651
Study of IL-22 IgG2-Fc (F-652) for Subjects With Grade II-IV Lower GI aGVHD treatment 1 / 2 completed NCT05090384
Pediatric GVHD Low Risk Steroid Taper Trial treatment 2 recruiting NCT03320928
Skin Disease and Pulmonary Mortality After Transplantation No drug interventions Not Available Not Available completed NCT04960644
MTX and Steroid as First-line Therapy for aGVHD treatment 3 active_not_recruiting NCT01754454
Safety and Efficacy of UC-MSC in Patients With Acute Severe Graft-versus-host Disease No drug interventions treatment 1 / 2 unknown_status NCT02254798
Biomarkers for Acute Graft-versus-host Disease No drug interventions Not Available Not Available unknown_status NCT01589549
Mesenchymal Stromal Cells for Acute Graft Versus Host Disease treatment 2 unknown_status NCT02641236
Gut Decontamination In Pediatric Allogeneic Hematopoietic prevention 2 completed NCT02917148
MicroRNAs as Diagnostic and Predictive Biomarkers for Acute Graft Versus Host Disease No drug interventions Not Available Not Available withdrawn NCT04677868
MTX and Steroid for aGVHD Treatment treatment 2 unknown_status NCT01485055
Infliximab and Basiliximab for Treatment of Steroid Refractory Acute Graft Versus Host Disease treatment 2 terminated NCT05263999
A Study of Itolizumab in Combination With Corticosteroids for the First-Line Treatment of Acute Graft Versus Host Disease (EQUATOR) treatment 3 recruiting NCT02848105
Valproic Acid With Methylprenisonlone for the Treatment of Acute GVHD treatment 2 unknown_status NCT05214066
Efficacy and Safety Study of 4-Day ATG Regimen for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT prevention 2 unknown_status NCT04061876
First Line Therapy for High Risk Acute GVHD treatment 2 completed NCT04397367
Low Dose Ruxolitinib in Combination With Methylprednisolone treatment 1 / 2 completed NCT03763318
A Study to Evaluate the Safety, Tolerability, PK, PD, and Clinical Activity of EQ001 in Subjects With aGVHD treatment 1 / 2 completed NCT05531266
Umbilical Cord Mesenchymal Stem Cells as First-line Treatment for Patients With Acute Graft Versus Host Disease No drug interventions treatment Not Available recruiting NCT02677181
Efficacy and Safety Study of ATG for Prophylaxis of aGVHD in Matched Sibling Donor PBSCT prevention 4 completed NCT03614143
Biomarker Study for Prediction of aGVHD No drug interventions Not Available Not Available unknown_status NCT04014790
RGI-2001 for the Prevention of Acute Graft-vs-Host Disease in Subjects Following Allogeneic Hematopoietic Stem Cell Transplantation prevention 2 completed NCT03764228
Human Amniotic Epithelial Cells Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation prevention Not Available unknown_status NCT02175615
Pharmacological Predictors of Successful Cyclosporine Acute GVHD Prophylaxis in Children Undergoing HSCT No drug interventions Not Available Not Available completed NCT04883918
ASC930 in Patients With Steroid-Refractory Acute Graft Versus Host Disease (SR-aGVHD) No drug interventions treatment 2 not_yet_recruiting NCT05236062
Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial No drug interventions supportive_care Not Available recruiting NCT04686929
Abatacept s.c. for aGVHD Prevention in Haplo-HCT prevention 1 / 2 recruiting NCT03847844
UCMSCs as Front-line Approach of Treatment for Patients With aGVHD No drug interventions treatment 1 / 2 active_not_recruiting NCT05123040
Ruxolitinib, Human Chorionic Gonadotropin (uhCG/EGF), and Dose De-escalated Corticosteroids treatment 1 / 2 recruiting NCT01220297
Sirolimus & Mycophenolate Mofetil as GvHD Prophylaxis in Myeloablative, Matched Related Donor HCT treatment 2 terminated NCT03339297
An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD) treatment 2 completed NCT04291261
Extracorporal Photopheresis With UVADEX Plus Standard Steroid Treatment for High Risk Acute Graft-versus-host Disease treatment 2 recruiting NCT05121142
Study of Ruxolitinib for Acute and Chronic Graft Versus Host Disease treatment 1 completed NCT03557749
Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies No drug interventions Not Available Not Available terminated NCT05149365
Sitagliptin for Prevention of aGVHD After Alternative Donor Transplantation prevention 3 recruiting NCT05078073
HBOT in the Treatment and Prevention of aGVHD No drug interventions treatment Not Available recruiting NCT02392780
Cannabidiol for the Treatment of Severe (Grades III/IV) Acute Graft-versus-host Disease treatment 2 unknown_status NCT03805789
The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant prevention 2 / 3 recruiting NCT03605940
A Study Comparing Corticosteroids Alone Versus Corticosteroids and Extracorporal Photopheresis (ECP) as First-line Treatment of Standard II Acute Graft-versus-host Disease treatment 2 unknown_status NCT05352269
Safety and Tolerability of FMT Capsules in Healthy Volunteers No drug interventions treatment 1 unknown_status NCT03172455
Early Access Program Using Alpha 1 Antitrypsin Infusion for Patients With Steroid Refractory Acute GvHD After Hematopoietic Stem Cell Transplantation (HSCT) Not Available Not Available no_longer_available NCT03148743
Fecal Microbiota Transplantation in Gut aGVHD Treated Not Available Not Available recruiting NCT06593834
A Clinical Study of Bacillus Coagulans in Acute Graft-Versus-Host Disease After Hematopoietic Stem Cell Transplantation prevention Not Available not_yet_recruiting NCT04745221
Efficacy and Safety of Auto-FMT in Preventing aGVHD No drug interventions prevention Not Available recruiting NCT02044185
Clinical Implications of HMGB1 in Patients Treated With Chemotherapy or Hematopoietic Stem Cell Transplantation No drug interventions Not Available Not Available unknown_status NCT04539470
Study to Evaluate the Safety and Pharmacokinetics of Efmarodocokin Alfa in Combination With Standard of Care in Participants Undergoing Allogeneic Hematopoietic Stem Cell Transplantation prevention 1 completed NCT01765634
Mesenchymal Stem Cells for Treatment of Refractory Acute Graft-versus-host Disease No drug interventions treatment 2 unknown_status NCT04285424
FMT for Steroid Resistant Gut Acute GVHD treatment 0 unknown_status NCT05362630
Infliximab Efficacy, TDM and Serum TNFα Levels in Pediatric HSCT Recipients With aGVHD: Prospective Observational Study No drug interventions Not Available Not Available recruiting NCT02659657
Prophylaxis Roles of IL-2 Treatment on GVHD After Transplantation prevention 2 unknown_status NCT03497273
Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese Subjects treatment 1 completed NCT01903473
Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD) prevention 2 terminated NCT04038827
Origin of CEC in Patients After Allo-HSCT No drug interventions Not Available Not Available completed NCT06294691
Effect of Stem Cell Infusion Time on aGVHD in Patients With Nonmalignant Hematologic Diseases No drug interventions prevention 3 not_yet_recruiting NCT05643638
A Study of CYP-001 in Combination With Corticosteroids in Adults With High-risk aGvHD treatment 2 recruiting NCT00282503
Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease treatment 3 terminated NCT05825833
Infliximab Efficacy in Relation to Therapeutic Drug Monitoring and Serum TNFα Levels in Pediatric HSCT No drug interventions Not Available Not Available completed NCT02743351
Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies No drug interventions prevention 1 / 2 completed NCT04971551
A Study of Jaktinib for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease. treatment 2 not_yet_recruiting NCT06294678
Effect of Stem Cell Infusion Time on aGVHD in Patients With Hematological Malignancies No drug interventions prevention 3 not_yet_recruiting NCT02241018
MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD No drug interventions treatment 2 / 3 unknown_status NCT01521039
Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease No drug interventions Not Available Not Available recruiting NCT03721965
Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects treatment 1 / 2 terminated NCT05673876
A Study to Assess the Safety and Pharmacokinetics of GDC-8264 in Combination With Standard of Care in Participants With Acute Graft-Versus-Host Disease (aGVHD) No drug interventions treatment 1 terminated NCT06490562
Low-dose Cyclophosphamide or CNI in the Prevention of Acute Graft-versus-host Disease After gDLI No drug interventions prevention Not Available not_yet_recruiting NCT02611180
Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease No drug interventions Not Available Not Available recruiting NCT03214289
Fecal Microbiota Transplantation for Steroid Resistant and Steroid Dependent Gut Acute Graft Versus Host Disease treatment 1 unknown_status NCT02245412
A Phase 2A Study of ALXN1007 in Participants With Newly Diagnosed Acute Lower Gastrointestinal Graft-Versus-Host Disease treatment 2 terminated NCT06394895
Donor Neutrophil Subsets to Predict the Risk of aGVHD No drug interventions Not Available Not Available active_not_recruiting NCT06026371
Fecal Microbiota Transplantation for the Prevention of Acute Graft Versus Host Disease in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation prevention 2 recruiting NCT05921305
Mini-dose MTX Plus Standard-dose Steroid for the Initial Treatment of Acute GVHD treatment 3 recruiting NCT00640497
Anti-CD3 & Anti-CD7 Ricin A Immunotoxin-Combination for Acute Graft Versus Host Disease No drug interventions treatment 1 / 2 withdrawn NCT04280471
Fecal Microbiota Transplantation for the Treatment of Severe Acute Gut Graft-Versus-Host Disease treatment 1 withdrawn NCT06473909
Combination of Steroid and Humanized CD25 Monoclonal Antibody as First-line Therapy for aGVHD No drug interventions treatment 2 not_yet_recruiting NCT02425813
Methylprednisolone Sodium Succinate in Treating Patients With Acute Graft-versus-Host Disease of the Gastrointestinal Tract treatment 2 withdrawn NCT02133924
Multicenter Study Of Natalizumab Plus Standard Steroid Treatment For High Risk Acute Graft-Versus-Host Disease treatment 2 completed NCT03158896
Evaluation of Umbilical Cord-Derived Wharton's Jelly Stem Cells for the Treatment of Acute Graft Versus Host Disease No drug interventions treatment 1 recruiting NCT06444022
hAESCs Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation No drug interventions prevention 0 not_yet_recruiting NCT05443425
Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies treatment 1 recruiting NCT02359929
BMT Autologous MSCs for GvHD treatment 1 completed NCT00038792
Phase I/II Trial rHuKFG for the Treatment of Steroid Refractory Gastrointestinal Acute GVHD No drug interventions treatment 1 / 2 terminated NCT02805946
Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections prevention 4 completed NCT00803010
Graft-Versus-Host Disease (GVHD) Prophylaxis After Allogeneic Peripheral Blood Hematopoietic Cell Transplantation prevention 2 completed NCT04958538
MTX and Steroid for III-IV aGVHD Treatment treatment 2 unknown_status NCT01140984
Intra Arterial (IA) Steroids Infusion for Hepatic Acute Hepatic Graft Versus Host Disease (aGVHD) treatment Not Available terminated NCT04521777
Studying Changes in Physical Function Measures in Stem Cell Transplant Patients at Risk for Steroid Myopathy No drug interventions supportive_care Not Available terminated NCT06386445
Study on the Serum Metabolic Markers and Early Complications After Allo-HSCT： Cohort Study No drug interventions Not Available Not Available not_yet_recruiting NCT00579397
Markers of Inflammation in Hematopoietic Stem Cell Transplant No drug interventions Not Available Not Available completed NCT03491215
Study of Pharmacokinetics, Activity and Safety of Ruxolitinib in Pediatric Patients With Grade II-IV Acute Graft vs. Host Disease treatment 1 / 2 completed NCT04006652
ApoGraft for the Prevention of Acute Graft Versus Host Disease in Haploidentical Hematopoietic Cell Transplant Recipients No drug interventions treatment 1 terminated NCT04910152
Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD treatment 1 / 2 terminated NCT00726375
The Use of Etanercept Enbrel as Sole Treatment for Grade I Acute Graft Versus Host Disease treatment 3 completed NCT05823675
Safety and Clinical Activity of Itolizumab in aGVHD treatment 1 recruiting NCT04095858
Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) treatment 3 terminated NCT06480630
Effectiveness and Safety of a Single-Center Clinical Study on a CD25 Monoclonal Antibody-Containing GVHD Prophylaxis Scheme to Reduce the Incidence of Severe Acute GVHD After Umbilical Cord Blood Transplantation for Malignant Hematologic Diseases prevention 2 not_yet_recruiting NCT00032773
Dose-finding Study Using Pentostatin for Injection in the Treatment of Steroid-refractory aGvHD treatment 1 / 2 terminated NCT02436460
A Study of AbGn-168H in Patients With Steroid Refractory Acute Graft-vs-Host Disease After Donor Stem Cell Transplant treatment 1 terminated NCT01475162
Tocilizumab for Treatment of Steroid Refractory Acute Graft-versus-Host Disease treatment 1 / 2 terminated NCT01596192
PETCT for Diagnosing and Monitoring Acute GVHD No drug interventions Not Available Not Available unknown_status NCT02687646
Clinical Trial With MSC for Graft Versus Host Disease Treatment No drug interventions treatment 1 / 2 completed NCT04976699
CD24Fc for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) treatment 3 active_not_recruiting NCT03701698
Ruxolitinib and Steroid As First Line Therapy for Acute GVHD prevention 2 terminated NCT04522843
Analysis of Intestinal Defensin Expression in Acute GVHD No drug interventions Not Available Not Available active_not_recruiting NCT05443464
Mesenchymal Stem Cells (MSCs) for Steroid Refractory Acute GVHD (SR-aGVHD) treatment 1 withdrawn NCT02631993
Photochemotherapy and Graft-versus-leukemia in Acute-leukemia No drug interventions Not Available Not Available completed NCT06164288
Safety and Efficacy Study of hAESCs Therapy for aGVHD No drug interventions treatment 1 not_yet_recruiting NCT06315309
Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant treatment 2 not_yet_recruiting NCT04118556
Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT treatment 1 / 2 recruiting NCT01530256
Exploratory Safety Study of ALD518 in Subjects With Steroid-refractory Acute Graft Versus Host Disease (GVHD) No drug interventions treatment 1 / 2 terminated NCT04373057
Prebiotic Galacto-oligosaccharide and Acute GVHD No drug interventions prevention 1 / 2 recruiting NCT06462365
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT) No drug interventions prevention 1 recruiting NCT03605927
CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease prevention 1 completed NCT05718791
CXCL9 and EASIX for Prediction of Acute Graft Versus Host Disease No drug interventions Not Available Not Available recruiting NCT03371667
To Compare the Efficacy of the Addition of Methotrexate (MTX) to Current Standard Acute Graft-versus-host Disease (GVHD) First-line Treatment With Corticosteroids treatment 3 active_not_recruiting NCT04284904
Role of aGVHD Biomarkers on aGVHD Risks No drug interventions Not Available Not Available unknown_status NCT00350181
Sirolimus & Mycophenolate Mofetil as GVHD Prophylaxis in Myeloablative, Matched Related Donor HCT treatment 2 completed NCT05368181
MAP-guided Preemptive Therapy of aGvHD prevention 2 recruiting NCT02806947
A Study to Evaluate Steroid-free Treatment for Standard-Risk aGVHD (BMT CTN 1501) treatment 2 completed NCT05855707
Wharton Jelly Mesenchymal Stromal Cells as GVHD Prophylaxis No drug interventions prevention 1 not_yet_recruiting NCT04220632
A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease treatment 1 / 2 terminated NCT04118075
PT-CY With or Without Low-dose ATG for Lymphoid Malignancies Undergoing Allo-HSCT No drug interventions prevention 2 completed NCT04645667
Tacrolimus in Allogeneic Hematopoietic Stem Cell Transplant (HCT) Not Available Not Available completed NCT05401955
Physiotherapy and Therapeutic Exercise Program in Graft-versus-host Disease (GvHD) No drug interventions supportive_care Not Available unknown_status