Neurologic toxicity (DBCOND0096567)

Identifiers

Synonyms
Neurological toxicity / Neurotoxicity / Neurotoxicity NOS / Neurotoxicity (disorder) / Neurotoxicity Syndromes

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT03330964
Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin NeurotoxicityNo drug interventionstreatmentNot Availableunknown_status
NCT01978743
Advanced Neuroimaging Evaluation of CNS Changes Associated With Efavirenz Therapy Switch to an Raltegravir-based Regimenbasic_scienceNot Availablecompleted
NCT04614987
Serum Neurofilament Light (NfL) as a Marker for Brain Injury in Individuals Undergoing Chimeric Antigen Receptor-modified T TherapyNo drug interventionsNot AvailableNot Availableterminated
NCT05094154
Effect of Antibiotic Choice On ReNal Outcomes (ACORN)treatment4completed
NCT01293851
Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve DamageNo drug interventionsNot AvailableNot Availableterminated
NCT00078845
Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumorssupportive_care2completed
NCT00471445
Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patientssupportive_care3completed
NCT02486198
Monosialotetrahexosylganglioside for Treatment of Oxaliplatin Induced Neurotoxicity in Gastrointestinal Cancertreatment3completed
NCT03089905
A Study to Compare the Long-term Outcomes After Two Different Anaestheticstreatment3active_not_recruiting
NCT00028509
Brain Function in Children Previously Treated on Clinical Trials POG-9605 and POG-9201No drug interventionsNot AvailableNot Availablecompleted
NCT00469937
Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastasessupportive_care1terminated
NCT00566852
Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumorssupportive_care3completed
NCT03628300
Neurotoxicity Evaluation of Beta-lactams in Intensive Care Unit and Identification of the Risk FactorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00305799
Hearing Loss and Dizziness in Patients Receiving Oxaliplatin for Solid TumorsNo drug interventionsNot AvailableNot Availablecompleted
NCT00755313
Effects of Chemotherapy on the Brain in Women With Newly Diagnosed Early-Stage Breast CancerNot AvailableNot Availablecompleted
NCT01381718
Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumorsupportive_care2completed
NCT00003624
Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancersupportive_care2terminated
NCT00834496
Switching From One Type of Anti-rejection Drug (Tacrolimus or Cyclosporine) to Another (Sirolimus) Approximately 90-180 Days After Liver TransplantationNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00027963
Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapysupportive_care3completed
NCT05040230
EEG Encephalopathy Patterns in Immune Effectors Cells-associated Neurotoxicity Syndrome (ICANS)Lay LanguageNo drug interventionsNot AvailableNot Availablecompleted
NCT00436774
Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01No drug interventionsNot AvailableNot Availableunknown_status
NCT01982591
Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing ChemotherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT03213392
Enzymatic Evaluation of General Anesthetic Induced Neurotoxicity in Patients With Aneurysmal Subarachnoid HemorrhageNo drug interventionsNot AvailableNot Availablecompleted
NCT01499940
Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through Vitamin D Pathwaysupportive_care2terminated
NCT00018967
Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Methotrexatesupportive_careNot Availablecompleted
NCT00884767
Biomarkers in Predicting Neurotoxicity in Patients With Colorectal Cancer Receiving Oxaliplatintreatment2unknown_status
NCT05089604
Tacrolimus Associated Tremors in Liver Transplantation: Immediate-Release Versus Extended-Release Formulationstreatment4recruiting
NCT01399372
Rituximab, Methotrexate, Vincristine Sulfate, Procarbazine Hydrochloride, and Cytarabine With or Without Radiation Therapy in Treating Patients With Primary Central Nervous System Lymphomatreatment2completed
NCT00003072
Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancersupportive_care2completed
NCT00365768
Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tumorssupportive_care2completed
NCT00452868
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brainsupportive_care0completed
NCT03823768
Envarsus Neurotoxicity Burden in Liver Transplant Patientstreatment4completed
NCT00003569
Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and PaclitaxelNot AvailableNot Availablecompleted
NCT02500810
Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patientsprevention2unknown_status
NCT00316914
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgerysupportive_care3completed
NCT00516503
Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancersupportive_care3completed
NCT00369564
Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancersupportive_care3completed
NCT00666484
Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphomatreatment2completed
NCT05798884
Electro-acupuncture for the Prevention and Treatment of Oxaliplatin-induced Neurotoxicity in Colorectal Cancer PatientsNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06144151
A Pilot Study for Pupillary Assessment to Predict CAR-T Related NeurotoxicityNo drug interventionsNot AvailableNot Availablerecruiting
NCT00281853
Nerve Changes in Patients Who Are Undergoing Chemotherapy or Biological Therapy for CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT00775645
S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing ChemoNo drug interventionssupportive_care3completed
NCT03461445
A Pilot Study to Evaluate Impact on Neurological Side Effects (Cognition, Memory, and Tremor) in Elderly (Age>65) Patientstreatment4completed
NCT00068445
Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancersupportive_care3completed
NCT00263861
Nerve Function in Older Diabetic Patients Who Are Undergoing Chemotherapy for Metastatic Solid TumorsNo drug interventionssupportive_careNot Availablecompleted
NCT00489411
Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancersupportive_care3completed
NCT00058071
Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancersupportive_care3completed
NCT01417507
Natural History of Brain Function, Quality of Life, and Seizure Control in Patients With Brain Tumor Who Have Undergone SurgeryNo drug interventionsNot AvailableNot Availablecompleted
NCT01415752
Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphomatreatment2active_not_recruiting
NCT00792142
Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myelomatreatment2completed
NCT01196442
Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With CancerNo drug interventionssupportive_careNot Availablecompleted
NCT01099449
Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapysupportive_care3completed
NCT04150913
A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicitytreatment2active_not_recruiting
NCT00860041
Acute Pain Caused by Paclitaxel in Patients With CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT05510596
Magnetic Resonance Imaging in Immune Effector Cell-Associated Neurotoxicity SyndromeNo drug interventionsdiagnosticNot Availablecompleted
NCT00112996
Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancersupportive_care3completed
NCT00978458
Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Gliomatreatment3active_not_recruiting
NCT05950386
Effects of Lead Exposure on Ferroptosis PathwayNo drug interventionsNot AvailableNot Availablerecruiting
NCT02864030
PAINTER: Polymorphism And INcidence of Toxicity in ERibulin Treatmenthealth_services_research4completed
NCT00952848
Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by ChemotherapyNo drug interventionssupportive_care2completed
NCT01372774
Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By SurgeryNo drug interventionstreatment3completed
NCT00727831
Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphomatreatment1 / 2completed
NCT00734773
Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSLtreatment0withdrawn
NCT00069927
Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depressionsupportive_care2terminated
NCT00085176
Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic LeukemiaNo drug interventionsNot AvailableNot Availablecompleted
NCT00046891
EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancersupportive_care3completed
NCT06021262
Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate ToxicityNo drug interventionsNot AvailableNot Availablerecruiting
NCT00301080
D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Painsupportive_care3terminated
NCT00363129
Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for CancerNo drug interventionssupportive_care3completed
NCT00754767
L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancersupportive_care4terminated
NCT01322672
Peri-Anesthetic Imaging of Cognitive DysfunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT01279681
Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancertreatment3terminated