chronic Progressive Fibrosing Interstitial Lung Disease (DBCOND0145708)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Nintedanib	A triple angiokinase inhibitor indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and in combination with docetaxel for non-small cell lung cancer.	Vascular endothelial growth factor receptor 1target Vascular endothelial growth factor receptor 2target Vascular endothelial growth factor receptor 3target Platelet-derived growth factor receptor alphatarget Platelet-derived growth factor receptor betatarget Fibroblast growth factor receptor 1target Fibroblast growth factor receptor 2target Fibroblast growth factor receptor 3target Receptor-type tyrosine-protein kinase FLT3target Tyrosine-protein kinase Lcktarget Tyrosine-protein kinase Lyntarget Proto-oncogene tyrosine-protein kinase Srctarget ATP-dependent translocase ABCB1transporter Cytochrome P450 3A4enzyme Solute carrier family 22 member 1transporter Albumincarrier UDP-glucuronosyltransferase 1A1enzyme UDP-glucuronosyltransferase 1A7enzyme UDP-glucuronosyltransferase 1A8enzyme UDP-glucuronosyltransferase 1A10enzyme Broad substrate specificity ATP-binding cassette transporter ABCG2transporter

Clinical Trials

Not Available