Cachexia

Also known as: Wasting syndrome / Cachectic / Wasting disease (disorder) / Wasting generalized / Wasting generalised / Cachexia (finding) / General health deterioration (finding)

Drug	Drug Name	Drug Description
DB00351	Megestrol acetate	A progestin that is administered orally to treat anorexia and cachexia or serious unexplained weight loss and is also used as an antineoplastic agent to treat certain types of malignancy.
DB00052	Somatotropin	A recombinant human growth hormone used as replacement therapy in various conditions of growth failure, growth hormone deficiency, and weakness in children and adults.

Drug	Drug Name	Target	Type
DB00351	Megestrol acetate	Progesterone receptor	target
DB00351	Megestrol acetate	Glucocorticoid receptor	target
DB00351	Megestrol acetate	P-glycoprotein 1	transporter
DB00351	Megestrol acetate	Cytochrome P450 3A4	enzyme
DB00052	Somatotropin	Growth hormone receptor	target
DB00052	Somatotropin	Prolactin receptor	target
DB00052	Somatotropin	Cytochrome P450 1A2	enzyme
DB00052	Somatotropin	Cytochrome P450 2C19	enzyme
DB00052	Somatotropin	P-glycoprotein 1	transporter

Drug	Drug Name	Phase	Status	Count
DB08877	Ruxolitinib	0	Recruiting	1
DB00171	ATP	1	Completed	1
DB09061	Cannabidiol	1	Completed	1
DB00470	Dronabinol	1	Completed	1
DB16888	GSK-2881078	1	Completed	2
DB14076	Interleukin-1 alpha, human recombinant	1	Completed	1
DB00762	Irinotecan	1	Completed	1
DB01167	Itraconazole	1	Completed	1
DB00351	Megestrol acetate	1	Completed	2
DB00960	Pindolol	1	Completed	1
DB13944	Testosterone enanthate	1	Completed	2
DB11895	Lenomorelin	1 / 2	Completed	1
DB12584	Bimagrumab	2	Completed	1
DB01211	Clarithromycin	2	Terminated	1
DB00434	Cyproheptadine	2	Completed	1
DB12078	Enobosarm	2	Completed	1
DB00846	Flurandrenolide	2	Terminated	1
DB16888	GSK-2881078	2	Completed	1
DB00441	Gemcitabine	2	Completed	1
DB01050	Ibuprofen	2	Recruiting	1
DB00065	Infliximab	2	Completed	2
DB00351	Megestrol acetate	2	Completed	4
DB09539	Omega-3-acid ethyl esters	2	Recruiting	1
DB00624	Testosterone	2	Completed	1
DB00486	Nabilone	2 / 3	Unknown Status	1
DB06645	Anamorelin	3	Completed	3
DB01248	Docetaxel	3	Completed	1
DB00005	Etanercept	3	Completed	1
DB01050	Ibuprofen	3	Completed	1
DB00065	Infliximab	3	Completed	1
DB00351	Megestrol acetate	3	Completed	4
DB00351	Megestrol acetate	3	Terminated	2
DB00351	Megestrol acetate	4	Completed	1
DB00351	Megestrol acetate	4	Withdrawn	1
DB00335	Atenolol	Not Available	Terminated	1
DB00482	Celecoxib	Not Available	Withdrawn	1
DB01050	Ibuprofen	Not Available	Terminated	1
DB00130	L-Glutamine	Not Available	Completed	1
DB01065	Melatonin	Not Available	Terminated	1