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Displaying targets 1751 - 1775 of 6103 in total
TargetOrganismDescription# of Drugs
DNA gyrase subunit BEscherichia coli (strain K12)DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner to maintain chromosom...  more10Details
DNA gyrase subunit BNeisseria gonorrhoeae (strain ATCC 700825 / FA 1090)A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manne...  more1Details
DNA helicase/primaseEnterobacteria phage T7ATP-dependent DNA helicase and primase essential for viral DNA replication and recombination. The helicase moves 5' -...  more2Details
DNA ligaseEnterococcus faecalis (strain ATCC 700802 / V583)DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in do...  more5Details
DNA ligaseHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in do...  more1Details
DNA ligase 1HumansDNA ligase that seals nicks in double-stranded during DNA repair. Also involved in DNA replication and DNA recombination2Details
DNA ligase 3HumansIsoform 3 functions as a heterodimer with DNA-repair protein XRCC1 in the nucleus and can correct defective DNA stran...  more1Details
DNA mismatch repair protein MutLEscherichia coli (strain K12)This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mis...  more2Details
DNA nucleotidylexotransferaseHumansTemplate-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-...  more2Details
DNA oxidative demethylase ALKBH2HumansDioxygenase that repairs alkylated nucleic acid bases by direct reversal oxidative dealkylation. Can process both dou...  more1Details
DNA polymeraseHuman herpesvirus 2 (strain 186)Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processi...  more2Details
DNA polymeraseVariola virusCatalyzes DNA synthesis. Acquires processivity by associating with a heterodimeric processivity factor comprised of t...  more1Details
DNA polymeraseHuman herpesvirus 1Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processi...  more3Details
DNA polymerase alpha catalytic subunitHumansCatalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which ...  more6Details
DNA polymerase alpha subunit BHumansAccessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which ...  more1Details
DNA polymerase betaHumansRepair polymerase that plays a key role in base-excision repair. During this process, the damaged base is excised by ...  more13Details
DNA polymerase catalytic subunitHHV-1Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processi...  more24Details
DNA polymerase catalytic subunitHHV-5Replicates viral genomic DNA in the late phase of lytic infection, producing long concatemeric DNA. The replication c...  more5Details
DNA polymerase catalytic subunitHHV-3Replicates viral genomic DNA. The replication complex is composed of six viral proteins: the DNA polymerase, processi...  more2Details
DNA polymerase delta catalytic subunitHumansAs the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-de...  more1Details
DNA polymerase delta subunit 4HumansAs a component of the tetrameric DNA polymerase delta complex (Pol-delta4), plays a role in high fidelity genome repl...  more1Details
DNA polymerase epsilon catalytic subunit AHumansCatalytic component of the DNA polymerase epsilon complex. Participates in chromosomal DNA replication. Required duri...  more1Details
DNA polymerase epsilon subunit 2HumansAccessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication2Details
DNA polymerase epsilon subunit 3HumansAccessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replicat...  more1Details
DNA polymerase epsilon subunit 4HumansAccessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication1Details
Displaying targets 1751 - 1775 of 6103 in total