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Displaying targets 1776 - 1800 of 6103 in total
TargetOrganismDescription# of Drugs
DNA polymerase gammaHumansNot Available1Details
DNA polymerase IEscherichia coli (strain K12)In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. It is able to ...  more2Details
DNA polymerase IGeobacillus stearothermophilusIn addition to polymerase activity, the recombinant enzyme has strand displacement and 5'-3' exonuclease activity, bu...  more1Details
DNA polymerase I, thermostableThermus aquaticusIn addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. Unlikely to have 3'-5' e...  more2Details
DNA polymerase III subunit epsilonEscherichia coli (strain K12)DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The...  more2Details
DNA polymerase III subunit tauEscherichia coli (strain K12)Part of the beta sliding clamp loading complex, which hydrolyzes ATP to load the beta clamp onto primed DNA to form t...  more1Details
DNA polymerase kappaHumansDNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the norma...  more3Details
DNA polymerase nuHumansDNA polymerase with very low fidelity that catalyzes considerable misincorporation by inserting dTTP opposite a G tem...  more1Details
DNA polymerase subunit gamma-1HumansCatalytic subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Replicates...  more1Details
DNA polymerase subunit gamma-2HumansAccessory subunit of DNA polymerase gamma solely responsible for replication of mitochondrial DNA (mtDNA). Acts as an...  more1Details
DNA polymerase thetaHumansLow-fidelity DNA polymerase with a putative helicase activity that promotes microhomology-mediated end-joining (MMEJ)...  more1Details
DNA primase small subunitHumansCatalytic subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alp...  more1Details
DNA repair nuclease/redox regulator APEX1HumansMultifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activit...  more2Details
DNA repair protein RAD51 homolog 1HumansHomologous DNA recombinase that catalyzes strand exchange, a key step in DNA repair through homologous recombination ...  more2Details
DNA repair protein XRCC4HumansDNA non-homologous end joining (NHEJ) core factor, required for double-strand break repair and V(D)J recombination. A...  more1Details
DNA sliding clamp PCNAHumansConfers DNA tethering and processivity to DNA polymerases and other proteins. Auxiliary protein of DNA polymerase del...  more4Details
DNA topoisomerase 1HumansReleases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by tra...  more56Details
DNA topoisomerase 1Escherichia coli (strain K12)Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcript...  more3Details
DNA topoisomerase 1Staphylococcus aureusReleases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcript...  more2Details
DNA topoisomerase 2HumansNot Available22Details
DNA topoisomerase 2-alphaHumansKey decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double...  more70Details
DNA topoisomerase 2-betaHumansKey decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double...  more56Details
DNA topoisomerase 4 subunit AStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation event...  more2Details
DNA topoisomerase 4 subunit AHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation event...  more16Details
DNA topoisomerase 4 subunit AEscherichia coli (strain K12)Topoisomerase IV is essential for chromosome segregation; it is the principal protein responsible for decatenating ne...  more12Details
Displaying targets 1776 - 1800 of 6103 in total