Targets

Advanced Filter

Filter by Group

Filter by Market Availability

Displaying targets 1876 - 1900 of 6103 in total
TargetOrganismDescription# of Drugs
DUTPaseCampylobacter jejuni subsp. jejuni serotype O:2 (strain NCTC 11168)Not Available1Details
Dynamin-1HumansCatalyzes the hydrolysis of GTP and utilizes this energy to mediate vesicle scission and participates in many forms o...  more1Details
Dynamin-1-like proteinHumansFunctions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-...  more2Details
Dynamin-2HumansCatalyzes the hydrolysis of GTP and utilizes this energy to mediate vesicle scission at plasma membrane during endocy...  more2Details
Dynein axonemal intermediate chain 1HumansComponent of dynein, a family of motor proteins essential for movement along microtubules. Required for structural an...  more1Details
DystrophinHumansAnchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophi...  more4Details
E-selectinHumansCell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-...  more11Details
E3 ubiquitin ligase TRAF3IP2HumansE3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein in...  more1Details
E3 ubiquitin-protein ligase CBLHumansE3 ubiquitin-protein ligase that acts as a negative regulator of many signaling pathways by mediating ubiquitination ...  more1Details
E3 ubiquitin-protein ligase CHIPHumansE3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Plays a rol...  more1Details
E3 ubiquitin-protein ligase HUWE1HumansE3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. ...  more1Details
E3 ubiquitin-protein ligase Mdm2HumansE3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. I...  more15Details
E3 ubiquitin-protein ligase pellino homolog 1HumansE3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the...  more1Details
E3 ubiquitin-protein ligase TRIM13HumansEndoplasmic reticulum (ER) membrane anchored E3 ligase involved in the retrotranslocation and turnover of membrane an...  more3Details
E3 ubiquitin-protein ligase UBR4HumansE3 ubiquitin-protein ligase involved in different protein quality control pathways in the cytoplasm. Component of the...  more2Details
E3 ubiquitin-protein ligase UHRF1HumansE3 ubiquitin-protein ligase that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modific...  more1Details
E3 ubiquitin-protein ligase XIAPHumansMulti-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling a...  more14Details
E3 ubiquitin-protein transferase MAEAHumansCore component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and medi...  more1Details
Early activation antigen CD69HumansTransmembrane protein expressed mainly on T-cells resident in mucosa that plays an essential role in immune cell home...  more1Details
Early endosome antigen 1HumansBinds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking1Details
Early growth response protein 1HumansTranscriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter reg...  more1Details
EcotinEscherichia coli (strain K12)General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as ...  more1Details
Ecto-NOX disulfide-thiol exchanger 2HumansMay be involved in cell growth. Probably acts as a terminal oxidase of plasma electron transport from cytosolic NAD(P...  more1Details
Ectonucleoside triphosphate diphosphohydrolase 1HumansCatalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs). The enzyme sequentially removes ...  more4Details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1HumansNucleotide pyrophosphatase that generates diphosphate (PPi) and functions in bone mineralization and soft tissue calc...  more3Details
Displaying targets 1876 - 1900 of 6103 in total