Heart Failure, Diastolic (DBCOND0000510)

Identifiers

Synonyms
Diastolic Heart Failure / Unspecified diastolic (congestive) heart failure / Diastolic heart failure (disorder) / Left ventricular failure, unspecified / Left ventricular failure / Left ventricular failures / LVF / Left ventricular insufficiency / Failure heart left / Left heart failure / Heart Failure, Left-Sided / Left heart failure (disorder) / Cardiac failure left / Left cardiac failure / Failure left heart

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06015776
Purinergic Signaling and the Postmenopausal HeartNo drug interventionsNot AvailableNot Availablerecruiting
NCT04584203
Diastolic dYsfunctioN AssessMent in critICally Ill PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03402490
Enhancement of Physical Activity in Elderly Patients With Diastolic Heart Failure by a Motivational InterventionNo drug interventionssupportive_careNot Availablecompleted
NCT05223751
Parasympathetic Augmentation Via Respiratory Training for Patients With Systolic Heart FailureNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT02256345
Pharmacokinetics, Pharmacodynamics, and Impact of Inorganic Nitrate on Exercise in HFpEFtreatment2completed
NCT02018497
Essential Hypotension and Allostasis RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT00839228
Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrometreatment2completed
NCT00585611
Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure PatientstreatmentNot Availableterminated
NCT05064709
Assessment of CCM in HF With Higher Ejection FractionNo drug interventionstreatmentNot Availablerecruiting
NCT01156636
Phosphodiesterase-5 (PDE5) Inhibition and Pulmonary Hypertension in Diastolic Heart Failuretreatment2 / 3completed
NCT02537041
Non-invasive Evaluation of Myocardial Stiffness by ElastographyNo drug interventionsdiagnosticNot Availablecompleted
NCT00709241
Psychosocial Patterns and Prognosis in Patients With Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT01599117
A Randomized Trial of Udenafil Therapy in Patients With Heart Failure With Preserved Ejection Fraction [ULTIMATE-HFpEF]treatment3unknown_status
NCT01163734
Ranolazine in Diastolic Heart FailureNot Available2completed
NCT00662116
Beginning a Randomized Evaluation of the AGE Breaker Alagebrium in Diastolic Heart Failure (BREAK-DHF-I)treatment2terminated
NCT02916225
High Intensity Interval Training Versus Moderate Continuous Training in Heart Failure With Preserved Ejection FractionNo drug interventionstreatmentNot Availablecompleted
NCT01778894
Mathematical Modeling to Determine Basic Muscle Properties in the Failing HeartNo drug interventionsNot AvailableNot Availableterminated
NCT02084992
A Study of a Technology-enabled Disease Management Program to Reduce Hospitalizations for Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT00939640
Effects of the Dietary Approaches to Stop Hypertension(DASH) Sodium-restricted Diet in Diastolic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT01913301
A Randomized Double-Blind, Placebo-Controlled, Multiple-Dose Study to Evaluate the Effects of Alagebrium on Exercise in Subjects With Diastolic Heart Failuretreatment2terminated
NCT00846404
Markers of Oxidative Stress Diastolic DysfunctionNo drug interventionsNot AvailableNot Availableunknown_status
NCT00309868
Study of Nesiritide in Diastolic Heart Failure.treatment1 / 2completed
NCT02053246
Improving Treatment Personalization of Pulmonary Hypertension Associated With Diastolic Heart Failuretreatment4terminated
NCT03882710
Metoprolol XR in Heart Failure With Normal Ejection Fractiontreatment2completed
NCT01157481
Diastolic Heart Failure Management by NifedipinetreatmentNot Availableunknown_status
NCT01583881
Denervation of the renAl sympathetIc nerveS in hearT Failure With nOrmal Lv Ejection FractionNo drug interventionstreatment2 / 3terminated
NCT00123955
PIE II: Pharmacological Intervention in the Elderly IItreatment3completed
NCT00293150
Reversing Endothelial and Diastolic Dysfunction and Improving Collagen Turnover in Diastolic Heart Failuretreatment4terminated
NCT04937790
Effects of Postural Balance Exercises in Patients With Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT03260621
CMR Exercise Stress Testing in HFpEFNo drug interventionsdiagnosticNot Availablecompleted
NCT00773084
Aliskiren and Renin Inhibition in Diastolic Heart FailuretreatmentNot Availablewithdrawn
NCT01944384
Impacts of Aldosterone Blockade on Myocardial Remodeling in Hypertensive Patients With Diastolic Failing Hearttreatment4completed
NCT02589977
Myocardial Perfusion, Oxidative Metabolism, and Fibrosis in HFpEFdiagnostic4completed
NCT00303498
A Study of the Effectiveness of Sitaxsentan Sodium in Patients With Diastolic Heart Failuretreatment2completed
NCT06485128
Investigating Multimodally Endothelial Dysfunction in Ocular and Systemic DiseaseNo drug interventionsdiagnosticNot Availablerecruiting
NCT02275793
The Regulation of Pulmonary Vascular Resistance in Patients With Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT04154878
2 New Measurements Used to Describe the Filling Phase of the Left Ventricle (LV).No drug interventionsNot AvailableNot Availablecompleted
NCT00574756
Effect of Ranolazine on Echocardiographic Indices of Diastolic DysfunctiontreatmentNot Availableterminated
NCT04160000
Treatment Of Atrial Fibrillation In Preserved Cardiac Function Heart FailureNo drug interventionstreatment4recruiting
NCT05408559
Prevention of Age-associated Cardiac and Vascular Dysfunction Using Avmacol EStreatment1 / 2recruiting
NCT02315859
Validation of New Non-Invasive Parameters of Diastolic Suction in the Left VentricleNo drug interventionsNot AvailableNot Availablecompleted
NCT00505336
The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart FailuretreatmentNot Availablecompleted
NCT02147613
High Intensity Interval Exercise in Diastolic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT03157219
Manipal Heart Failure Registry (MHFR)No drug interventionsNot AvailableNot Availableunknown_status
NCT00718939
Rheos® Diastolic Heart Failure TrialNo drug interventionstreatmentNot Availablecompleted
NCT00720525
Pulsatile and Steady State Hemodynamics in Diastolic Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT03338374
Cardiac Resynchronisation Therapy Versus Rate-responsive Pacing in Heart Failure With Preserved Ejection FractionNo drug interventionstreatmentNot Availablecompleted
NCT02254382
Positive Airway Pressure Therapy Study in Sleep Apnea and Diastolic Heart FailureNo drug interventionstreatmentNot Availableterminated
NCT01047631
Role of Exercise in Diastolic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT02446327
The Metabolic Road to Diastolic Heart Failure: Diastolic Heart Failure StudyNo drug interventionsdiagnosticNot Availablecompleted
NCT01431027
Left Ventricular Torsional Hysteresis: A Global Parameter for Diastolic FunctionNo drug interventionsNot AvailableNot Availablecompleted
NCT03041376
Pedometer-Based Walking Intervention in Patients With Chronic Heart Failure With Preserved Ejection FractionNo drug interventionspreventionNot Availableunknown_status
NCT01030991
Classification of Heart Failure With Preserved Ejection FractionNo drug interventionsNot AvailableNot Availablecompleted
NCT01185067
Physiological Effects of Grape Seed Extract in Diastolic Heart Failuretreatment1completed
NCT02499601
CORolla® TAA for Heart Failure With Preserved Ejection Fraction (HFpEF) and Diastolic Dysfunction (DD)No drug interventionstreatmentNot Availableunknown_status
NCT02963272
ST2 for the Management of Heart Failure - STADE-HFNo drug interventionsdiagnosticNot Availablecompleted
NCT00083772
Use of Nesiritide in the Management of Acute Diastolic Heart Failuretreatment4terminated
NCT01942395
Dietary Approaches to Stop Hypertension in 'Diastolic' Heart Failure 2 (DASH-DHF 2)No drug interventionstreatmentNot Availableterminated
NCT04721314
Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection FractionNo drug interventionstreatmentNot Availablecompleted
NCT00757055
If Channel Blockade With Ivabradine in Patients With Diastolic Heart Failuretreatment2withdrawn
NCT04950218
The Psoriasis Echo StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT04940312
MyoMobile Study: App-based Activity Coaching in Patients with Heart Failure and Preserved Ejection FractionNo drug interventionsNot AvailableNot Availablecompleted
NCT05139472
Impact of Empagliflozin on Functional Capacity in Heart Failure with Preserved Ejection Fractiontreatment4completed
NCT05764564
External Body Pressure in Heart Failure With Preserved Ejection FractionNo drug interventionsdiagnostic1 / 2recruiting
NCT04757584
Pilot Deprescribing N-of-1 Trials for Beta-blockers in HFpEFother4completed
NCT03924479
Respiratory Muscle Function in Heart FailureNo drug interventionsotherNot Availablecompleted
NCT02145351
Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT05647577
The Relationship Between Inflammatory ARTritis and CArdiac DIseAseNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT02941705
Regression of Fibrosis & Reversal of Diastolic Dysfunction in HFpEF Patients Treated With Allogeneic CDCstreatment2completed
NCT04767061
Impact of Beta-blockers on Physical Function in HFpEFother4completed
NCT05475028
Network Medicine Approaches to Classify Heart Failure With PReserved Ejection Fraction by Signatures of DNA Methylation and Point-of-carE Risk calculaTors (PRESMET)No drug interventionsNot AvailableNot Availablecompleted
NCT03133793
CoQ10 and D-ribose in Patients With Diastolic Heart Failuretreatment2completed
NCT05322109
Cardiac Magnetic Resonance Tomography for Heart Failure With Preserved Ejection FractionNo drug interventionsNot AvailableNot Availablecompleted
NCT03476785
Prevention of Cardiovascular Stiffening With Aging and Hypertensive Heart DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT03240237
CCM in Heart Failure With Preserved Ejection FractionNo drug interventionsotherNot Availablecompleted
NCT00820352
Safety and Efficacy of Bosentan in Patients With Diastolic Heart Failure and Secondary Pulmonary Hypertensiontreatment3completed
NCT04475042
Stratified Treatment to Ameliorate Diastolic Left Ventricular Stiffness in Heart Failure With Preserved Ejection Fractiontreatment2unknown_status
NCT02155842
Exercise Training in Treating Diastolic Heart FailureNo drug interventionstreatmentNot Availablewithdrawn
NCT03387813
Hemodynamic-GUIDEd Management of Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT00799435
Evaluating the Use of Exenatide in People With Type 2 Diabetes and Diastolic Heart Failuretreatment4terminated
NCT04145635
The Aortix CRS Pilot StudyNo drug interventionstreatmentNot Availablecompleted
NCT02636439
Exercise Intolerance in Elderly Patients With HFpEF(Heart Failure With Preserved Ejection Fraction)No drug interventionstreatmentNot Availablecompleted
NCT05585125
A Preliminary Study for INFORMEDNo drug interventionsother4recruiting
NCT02762825
Novel Cardiac Rehabilitation in Patients Heart Failure and Preserved Ejection FractionNo drug interventionstreatmentNot Availableterminated
NCT05638230
Relative Importance of Cardiovascular Risk Factors and Echocardiographic Parameters Affecting Left Atrial StrainNo drug interventionsNot AvailableNot Availablerecruiting
NCT02115230
Renal Denervation in Patients With Heart Failure With Normal LV Ejection FractionNo drug interventionstreatmentNot Availableunknown_status
NCT03830957
Efficacy and Safety of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blockersupportive_careNot Availableunknown_status
NCT04071626
Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failuretreatment4terminated
NCT03410966
Atrial Fibrillation AblationNo drug interventionsbasic_scienceNot Availablecompleted
NCT04112576
Physiological Signals, Activity and Posture for Surface Mounted Insertable Cardiac Monitor in Heart Failure StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02946476
Prognostic Impact of Noncardiac Comorbidities in Heart Failure PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT05752760
Pilot Study Lp299v Supplementation in Chronic Heart FailureNo drug interventionsbasic_scienceNot Availablerecruiting
NCT00959660
Exercise Intolerance in Elderly Patients With Diastolic Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT02334891
Kyoto Congestive Heart Failure StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02993601
Feasibility Study of a New Peripheral Oedema Monitor for Heart FailureNo drug interventionsNot AvailableNot Availablecompleted
NCT04603404
Multimodality Imaging in the Screening, Diagnosis and Risk StratifictiON of HFpEFNo drug interventionsNot AvailableNot Availablerecruiting
NCT03028168
Yôga and Breathing Techniques Training in Patients With Heart Failure and Preserved Ejection FractionNo drug interventionshealth_services_researchNot Availablecompleted
NCT05479669
Value of Intense Phenotyping in Heart Failure With Preserved Ejection FractionNo drug interventionsNot AvailableNot Availablerecruiting
NCT02059512
Autologous Bone Marrow Mononuclear Cells in the Combined Treatment of Coronary Heart DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT04336995
Exercise Pulmonary Transit TimeNo drug interventionsdiagnostic4completed
NCT04602338
Diagnosis and OutcoMes evaluAtIoN of Multicenter Patients With HFpEF Using Multimodality ImagingNo drug interventionsNot AvailableNot Availablerecruiting
NCT04179643
NAN-101 in Patients With Class III Heart FailureNo drug interventionstreatment1recruiting
NCT02408003
Changes in Cardiac Deformation Following Physiologic Alterations and Inotropic Support.treatmentNot Availablecompleted
NCT03312387
Muscle, Essential Amino Acids, and eXercise in Heart FailureNo drug interventionsotherNot Availableterminated
NCT03753087
Effects of Empagliflozin on Exercise Capacity and Left Ventricular Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction and Type-2 Diabetes Mellitustreatment4completed
NCT05989945
HIDRAdenitis Suppurativa and HEART DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT05768698
Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking EchocardiographyNo drug interventionsNot AvailableNot Availablerecruiting
NCT01182805
Radiofrequency-based Speckle Tracking Echocardiography to Evaluate Diastolic FunctionNo drug interventionsdiagnostic1 / 2completed
NCT05887271
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection FractionNo drug interventionstreatment2 / 3recruiting
NCT02425371
Optimized Management of Comorbidity in Heart Failure With Preserved Ejection Fraction in the Elderly (>60 Years)No drug interventionstreatment3unknown_status
NCT01901809
Diuretics and Dopamine in Heart Failure With Preserved Ejection Fractiontreatment4completed
NCT03448185
Improving Metabolic Health in Patients With Diastolic DysfunctionNo drug interventionstreatmentNot Availablecompleted
NCT02911337
Weight Loss as Therapy for Heart Failure With Preserved Ejection FractionNo drug interventionstreatmentNot Availablecompleted
NCT05677100
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart FailureNo drug interventionstreatmentNot Availablerecruiting
NCT02649400
Assessment of Functional Capacity and Inflammatory Markers in Women With Heart Failure With Preserved Ejection FractionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05162859
Exercise Training in Heart Failure With Preserved Ejection Fraction - a Long-term Follow-upNo drug interventionsNot AvailableNot Availablecompleted
NCT05425459
RESPONDER-HF TrialNo drug interventionstreatmentNot Availablerecruiting
NCT05140642
Safety and Efficacy Study of AI LVEFNo drug interventionsdiagnosticNot Availablecompleted
NCT04281849
Balance, Aerobic Capacity, Mobility and Strength in Patients Hospitalized for Heart Failure (BAMS-HF) ProgramNo drug interventionstreatmentNot Availablecompleted
NCT06061549
Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Preserved Ejection FractionNo drug interventionstreatment1recruiting
NCT01726049
Sildenafil in HFpEF (Heart Failure With Preserved Ejection Fraction) and PHtreatment3completed
NCT01431313
Inhaled Nitrite in Subjects With Pulmonary Hypertensiontreatment2completed
NCT05577819
Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEFNo drug interventionsdiagnosticNot Availablerecruiting
NCT03111017
Mechanisms and Management of Exercise Intolerance in Older Heart Failure PatientsNo drug interventionsbasic_scienceNot Availablecompleted
NCT03671122
PREFERS (Preserved and Reduced Ejection Fraction Epidemiological Regional Study) Stockholm Heart Failure StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT02983448
Noninvasive Neuromodulation to Reserve Diastolic DysfunctionNo drug interventionstreatmentNot Availablecompleted
NCT04154657
Mechanisms of Right Ventricular Adaptation in Patients With Heart Failure With Preserved Ejection FractionNo drug interventionsdiagnosticNot Availableunknown_status
NCT04573166
Personalized Atrial Septostomy for Heart FailureNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT00628082
Energetic Abnormalities in Heart Failure With Preserved Ejection FractionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05128331
sPERMIdine supplemenTation on Metabolic, Neuronal and Cardiovascular Response to Exercise TRAININGNo drug interventionstreatmentNot Availableunknown_status
NCT04450576
HbA1c as an Early Serologic Marker for the Hemodynamic Progression of Stage A Heart FailureNo drug interventionsNot AvailableNot Availableunknown_status
NCT06009276
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness StatusNo drug interventionsNot AvailableNot Availablerecruiting
NCT05008692
Apple-CPET Ted Rogers Understanding Exacerbations of Heart FailureNo drug interventionsNot AvailableNot Availablerecruiting
NCT04068844
Mechanisms of Exercise Intolerance in Heart Failure With Preserved Ejection FractionNo drug interventionstreatmentNot Availablerecruiting
NCT04682704
The Effect of Different Low-Level Tragus Stimulation Parameters On Autonomic Nervous System FunctionNo drug interventionstreatmentNot Availablerecruiting
NCT06084468
Cardiac Structure and Function in Patients With Cystic FibrosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04546555
Physiologic Accelerated Pacing as a Treatment in Patients With Heart Failure With Preserved Ejection FractionNo drug interventionsotherNot Availablecompleted
NCT03183323
Implementation of Telerehabilitation In Support of HOme-based Physical Exercise for Heart FailureNo drug interventionstreatmentNot Availablecompleted
NCT01046838
SIDAMI - Sildenafil and Diastolic Dysfunction After Acute Myocardial Infarction (AMI)treatment4completed