Colorectal Adenocarcinoma (DBCOND0029808)

Identifiers

Synonyms
Adenocarcinoma of the Colorectal / Colorectal Adenocarcinoma (CRC) / Colorectal Adenocarcinomas / Colorectal adenocarcinoma / Adenocarcinoma of large intestine (disorder)

Associated Data

Indicated Drugs and Targets
Not Available
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01447732
Phase 1 Study of CEP-37250/KHK2804 in Subjects With Advanced Solid TumorsNo drug interventionstreatment1completed
NCT04171141
Study to Test the Safety and Tolerability of PF-07062119 in Patients With Selected Advanced or Metastatic Gastrointestinal Tumors.No drug interventionstreatment1terminated
NCT04739072
Minimal Residual Disease Assessment in Patients with Colorectal Cancer, the MiRDA-C StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT05736731
A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 ExpressionNo drug interventionstreatment1 / 2recruiting
NCT06051695
A Study to Evaluate the Safety and Efficacy of A2B694, a Logic-gated CAR T, in Subjects With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionNo drug interventionstreatment1 / 2recruiting
NCT06640166
Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.treatment2recruiting
NCT05620134
Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancertreatment1 / 2active_not_recruiting
NCT05731271
A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid TumorsNo drug interventionstreatment1 / 2active_not_recruiting
NCT03366155
Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Livertreatment2recruiting
NCT05480306
Phase 2 Study of DKN-01 in Colorectal Cancertreatment2active_not_recruiting
NCT05902988
A Phase I/II Study of VLS-1488 in Subjects with Advanced CancerNo drug interventionstreatment1 / 2recruiting
NCT03800602
Nivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal Cancertreatment2completed
NCT02835833
Study of Nintedanib Plus Bevacizumab in Advanced Solid Tumorstreatment1completed
NCT05411133
Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer PatientsNo drug interventionstreatment1recruiting
NCT05988645
Performance and Safety of MiWEndo-assisted Colonoscopy (MiWEndo II)No drug interventionsdiagnosticNot Availablerecruiting
NCT03507998
Phase 1 Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal Tumorstreatment1unknown_status
NCT04963283
Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancertreatment2active_not_recruiting
NCT06225011
Fluoxetine for the Modification of Colorectal Tumor Immune Cells Before Surgery in Patients With Colorectal Cancertreatment1not_yet_recruiting
NCT03367611
Use of iFOBT in Patients Presenting With Alarm Symptoms of Colorectal CancerNo drug interventionsdiagnosticNot Availablecompleted
NCT06314971
Predicting Local and Distant Recurrence in T1 Colorectal CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04094688
Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancertreatment3active_not_recruiting
NCT04196088
To Compare Artificial Intelligence Software Aided Adenoma Detection in Screening Colonoscopies Versus Standard Colonoscopy Without Artificial Intelligence Software Assistance in Participants Between 45 and 75 Years of AgeNo drug interventionsscreeningNot Availableunknown_status
NCT03300609
5-FU Based Maintenance Therapy in RAS Wild Type Metastatic Colorectal Cancer After Induction With FOLFOX Plus Panitumumabtreatment3terminated
NCT02638909
Study of Oral Ceritinib in Patients With ALK and ROS1 Activated Gastrointestinal Malignanciestreatment2terminated
NCT01114256
FNA Tumor Sampling for CD137 Modulation: A Pilot StudyNo drug interventionsNot AvailableNot Availableterminated
NCT03599752
Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung MetastasesNo drug interventionstreatment2active_not_recruiting
NCT05504252
METIMMOX-2: Metastatic pMMR/MSS Colorectal Cancer - Shaping Anti-Tumor Immunity by Oxaliplatintreatment2recruiting
NCT01367275
Irinotecan Plus Brivanib in Metastatic Colorectal Cancer (CRC) Enriched for Elevated Levels of Plasma FGFtreatment2terminated
NCT05200442
A Study of VS-6766 and Cetuximab in Patients With Advanced Colorectal Cancertreatment1 / 2recruiting
NCT05477836
Feasibility and Safety of MiWEndo-assisted ColonoscopyNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT03369041
Study of the Practice of Debiri in FranceNot AvailableNot Availableunknown_status
NCT00165217
Capecitabine and Thalidomide in Previously Treated Metastatic Colorectal Carcinomatreatment2completed
NCT06314958
Stage II/III Colorectal Cancer RecurrenceNo drug interventionsNot AvailableNot Availablerecruiting
NCT06118658
Chemotherapy Sequential Tislelizumab After Radical Resection in Patients With dMMR/MSI-H or POLE/POLD1 Mutationstreatment2not_yet_recruiting
NCT03706235
Colvera for Detection of Disease RecurrenceNo drug interventionsNot AvailableNot Availablecompleted
NCT02650635
TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients With Metastatic, Persistent, Recurrent, or Progressive Solid Tumorstreatment1terminated
NCT03368963
TAS102 in Combination With NAL-IRI in Advanced GI Cancerstreatment1 / 2recruiting
NCT03576963
Guadecitabine and Nivolumab in Treating Refractory Metastatic Colorectal Cancertreatment1 / 2withdrawn
NCT05678257
A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancertreatment2terminated
NCT06067620
Robotic Right Hemicolectomy Versus Laparoscopic Right HemicolectomyNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00593060
Temsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal Cancertreatment1completed
NCT02757391
CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumorstreatment1terminated
NCT03803891
Endoscopic Full-Thickness Resection In ColonNo drug interventionsNot AvailableNot Availableunknown_status
NCT06271980
Early-Onset Colorectal Cancer RecurrenceNo drug interventionsNot AvailableNot Availablecompleted
NCT03468244
Clinical Study of Personalized mRNA Vaccine Encoding Neoantigen in Patients With Advanced Digestive System NeoplasmsNo drug interventionstreatmentNot Availableunknown_status
NCT06342440
Early Detection of Advanced Adenomas and Colorectal CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT06134440
ImmunoNutrition and Colorectal Adenocarcinoma Surgery - INCAS StudyNo drug interventionstreatmentNot Availablerecruiting
NCT01552967
Efficacy and Safety Study of a Modified XELOX Regimen in First-Line Treatment of Metastatic Colorectal Adenocarcinomatreatment2unknown_status
NCT04731467
A Study of CM24 in Combination With Nivolumab in Adults With Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT04111172
A Vaccine (Ad5.F35-hGCC-PADRE) for the Treatment of Gastrointestinal AdenocarcinomaNo drug interventionstreatment2suspended
NCT03683446
Trends and Outcomes in Laparoscopic Versus Open Surgery for Rectal CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT05247346
Early Detection of Cancer Onset Based on Sensing Field Cancerization at the Organ Level in the Alimentary Tract Using an Integrated Stimulated Raman/Scattering Modality for Endoscopic Real-time in Vivo MeasurementsNo drug interventionsdiagnosticNot Availablerecruiting
NCT04108481
Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancertreatment1 / 2suspended
NCT03095781
Pembrolizumab and XL888 in Patients With Advanced Gastrointestinal Cancertreatment1completed
NCT03050814
Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004treatment2terminated
NCT04894123
Cardiovascular Events From Trifluridine/Tipiracil +/- Oxaliplatin in Colorectal/Oesogastric Adenocarcinoma Patientstreatment2terminated
NCT04380103
A Phase I/II Study of XELOXIRI and Bevacizumab as First-line Treatment in Metastatic Colorectal Cancertreatment1 / 2unknown_status
NCT00034190
Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Colorectal Adenocarcinomatreatment2completed
NCT04457284
Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancertreatment2active_not_recruiting
NCT04870879
Colorectal Metastasis and Liver Transplantation With Organs From Deceased DonorsNo drug interventionstreatmentNot Availablerecruiting
NCT03715933
Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomastreatment1recruiting
NCT02758951
Perioperative Systemic Therapy for Isolated Resectable Colorectal Peritoneal Metastasestreatment2 / 3active_not_recruiting
NCT02413853
Combination Chemotherapy and Bevacizumab With or Without PRI-724 in Treating Patients With Newly Diagnosed Metastatic Colorectal Cancertreatment2withdrawn
NCT06050447
Factors Affecting the Results of Treatment of Patients With Colorectal CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT02709811
Safety and Feasibility of Electrochemotherapy in Unresectable Colorectal Adenocarninoma Liver MetastasesNo drug interventionstreatment1 / 2terminated
NCT06076811
DANISH.MRD: Danish Assessment of Minimal Residual Disease by Liquid BiopsiesNo drug interventionsNot AvailableNot Availablerecruiting
NCT04148378
A Pilot Study to Explore the Role of Gut Flora in Colorectal CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT03781778
Pilot Trial of Resistant Starch in Stage I-III Colorectal Cancer SurvivorsNo drug interventionsprevention2terminated
NCT03373188
VX15/2503 and Immunotherapy in Resectable Pancreatic and Colorectal Cancertreatment1completed
NCT04054752
Vaccine Response With NT-I7treatment1withdrawn
NCT03958500
The Problem of Colorectal Anastomosis SafetyNo drug interventionsdiagnosticNot Availablecompleted
NCT03376659
Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinomatreatment1 / 2terminated
NCT04474470
A Study to Evaluate NT219 Alone and in Combination With ERBITUX® (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancertreatment1 / 2active_not_recruiting
NCT04898842
Feasibility Study of a 4 Stage Bowel Obstruction Cancer DietNo drug interventionstreatmentNot Availablecompleted
NCT02788006
Efficacy and the Safety of Regorafenib in Patients Aged More Than 70 Years With a Metastatic Colorectal Adenocarcinoma .treatment2completed
NCT00597506
Expanded Cohort for Metastatic Colorectal Cancer (MCRC) Using Bevacizumab + Everolimustreatment2completed
NCT05635149
Predictive Factors for Outcomes of Fruquintinib Plus Immunotherapy in Colorectal CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT03708536
Bevacizumab Plus Capecitabin vs S-1 as Maintenance Treatment Following First-line Chemotherapy in the Patients With Advanced Colorectal Adenocarcinomatreatment3withdrawn
NCT02292758
Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgerytreatment2completed
NCT03699163
The Colorectal Breath Analysis (COBRA) StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02837263
PI Pembro in Combination With Stereotactic Body Radiotherapy for Liver Metastatic Colorectal Cancertreatment1completed
NCT01856322
Surgery Plus Sulindac or Surgery Alone for Advanced Colorectal Cancertreatment2terminated
NCT03221920
Very Low Carbohydrate Diet Effects to GPS, Serum Lactate and TNF Alpha on Colorectal CancerNo drug interventionssupportive_careNot Availableunknown_status
NCT03206073
A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancertreatment1 / 2completed
NCT05592873
Oncological Impact of Lateral Nodes in Rectal CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT06540027
The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal CancerNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT04430127
The Role of Quantitative Measures on Dual-energy CT in the Prediction of Colorectal AdenocarcinomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT04802876
Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumorstreatment2recruiting
NCT01844076
Quinacrine-Capecitabine Combinatorial Therapy for Advanced Stage Colorectal Adenocarcinomatreatment1 / 2terminated
NCT06349044
A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.treatmentNot Availablerecruiting
NCT03642067
Study of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancertreatment2active_not_recruiting
NCT06342401
Early Onset Colorectal Cancer DetectionNo drug interventionsNot AvailableNot Availablerecruiting
NCT04773769
Study of Guanábana Leaves for The Treatment of Patients With Gastric, Gastroesophageal Junction, Pancreatic and Colorectal Adenocarcinomas; Hepatocellular Carcinoma, and Low Grade LymphomasNo drug interventionstreatmentNot Availableunknown_status
NCT06339346
Analysis of Histopathological Factors Predictive of Lymph Node Involvement and Management Practices in pT1 Colorectal Cancers Treated by Primary Endoscopic ResectionNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00168155
Study of 5-FU + Leucovorin + CPT-11 in Patients With Resectable Liver Metastases From Colorectal AdenocarcinomaNo drug interventionstreatment2completed
NCT03149523
Exhaustive Genetic and Immunological Characterization of Colon, Kidney and Liver TumorsNo drug interventionsNot AvailableNot Availableunknown_status