Idiopathic Parkinson's Disease (DBCOND0030897)

Identifiers

Synonyms
Idiopathic Parkinson Patients / Idiopathic Parkinsons Disease / Parkinson Disease, Idiopathic / Parkinson's Disease, Idiopathic / Idiopathic Parkinson's Disease (PD) / Parkinson's Disease,Idiopathic / Idiopathic Parkinsonism / Idiopathic Parkinson Disease / Idiopathic Parkinson's disease / Parkinson's disease without dyskinesia, without mention of fluctuations / Parkinson's disease (disorder) / Parkinson Disease / Hemiparkinsonism / Parkinson's disease / Paralysis agitans / Disease Parkinson's / Parkinson's disease NOS / Parkinson's syndrome

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Dihydro-alpha-ergocryptine
A nootropic with an unknown mechanism of action indicated in individuals over sixty who manifest signs and symptoms of an idiopathic decline in mental capacity.
Ropinirole
A non-ergoline dopamine agonist used to treat the symptoms of Parkinson's disease and Restless Legs Syndrome.
Tolcapone
A catechol-O-methyltransferase (COMT) inhibitor used as adjunct therapy in the symptomatic management of idiopathic Parkinson's disease.
Trihexyphenidyl
An antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS).
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT02937727
MRI Compatible and Long-term LFP Recordable Deep Brain Stimulation on PD PatientsNo drug interventionstreatment1unknown_status
NCT02250690
Neuromodulation on Motor Function in Parkinson's DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT06623591
Ameliorating Effects and Mechanisms of TaVNS on Constipation in PD Patients.No drug interventionstreatmentNot Availablenot_yet_recruiting
NCT06609681
Parkinson Disease: A Model of National Digital Interventions to Prevent or Slow a Rise of Non-CommunicableNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05919160
A High-density Microelectrode for Human Neuronal RecordingsNo drug interventionsdevice_feasibilityNot Availableenrolling_by_invitation
NCT04731246
Video-oculography and Parkinson's DiseaseNo drug interventionsotherNot Availablerecruiting
NCT05575479
PA Behavior and HRQoL in Parkinson's Disease Patients Patients: Role of Social Cognitive VariablesNo drug interventionsNot AvailableNot Availablecompleted
NCT00244387
Rotigotine Patch in Subjects With Advanced Stage, Idiopathic Parkinson's Disease Who Are Not Well Controlled on Levodopatreatment3completed
NCT06583005
Vibrotactile Coordinated Reset for Parkinsons Patients Who Are on Dopaminergic MedicationNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT00507715
Study of the Modification of the Pharmacokinetic Profile of Levodopa by the Fiber Plantago Ovata HuskNo drug interventionstreatment1completed
NCT02879136
TAME-PD - Physical Therapy, Atomoxetine and, Methylphenidate, to Enhance Gait and Balance in Parkinson's Diseasetreatment0recruiting
NCT05357989
A Double-blind Study to Investigate Efficacy and Safety of Buntanetap Compared With Placebo in Participants With Early PDtreatment3completed
NCT03022201
Comparing the Therapeutic Efficacy and Safety of DA-9701 With Domperidone in Patients With Parkinson's Diseasetreatment4completed
NCT02283073
Study for the Early Diagnosis of Parkinson's DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01883973
MER Versus MRI Guidance DBS in Parkinson's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT06390163
Effects of Sensory-Motor Integration Training in Patients with Idiopathic Parkinson's DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT05437003
A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in PD PatientsNo drug interventionsotherNot Availablecompleted
NCT03700684
Voice Treatment for Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT02641054
Efficacy Phase IIa Study of CVXL-0107 in Advanced Parkinson's Diseasetreatment2completed
NCT05699161
Adipose-derived Stromal Vascular Fraction Cells to Treat ParkinsonNo drug interventionstreatment1 / 2completed
NCT05471609
Sustained Release Oral Formulation for Treatment of Parkinson's Diseasetreatment0suspended
NCT03944785
Clinical Outcome Assessment of Parkinson's Disease Patients Treated With XADAGO (Safinamide)Not AvailableNot Availablecompleted
NCT05832775
Study to Assess the Safety of MRx0029 or MRx0005 Compared to Placebo, in People With Parkinson'sNo drug interventionstreatment1withdrawn
NCT05103618
Effect of Meditation and Controls and Subjects With Parkinson's Disease on Brain Activity Measured by fMRI With FDOPANo drug interventionsother2not_yet_recruiting
NCT02723396
Sleep, Awake & Move - Part INo drug interventionsNot AvailableNot Availablecompleted
NCT03652363
GDNF in ideopathicParkinsons DiseaseNo drug interventionstreatment2completed
NCT03037463
Measuring Parkinson's Disease With Tear FluidNo drug interventionsNot AvailableNot Availablecompleted
NCT00599339
Transdermal Rotigotine User Surveillance StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT04510922
Lundbeck TOMs Orthostatic Hypotensionother4completed
NCT03683225
A Study to Evaluate in Patients With Parkinsonian Type DisordersNo drug interventionstreatment2active_not_recruiting
NCT05027620
Feasibility of Motor-cognitive Home Training for Parkinson's Disease Using eHealth TechnologyNo drug interventionstreatmentNot Availablecompleted
NCT02393027
Quantification of Dopamine Active Transporter (DAT) in Humans: Validation of a New Radiophamaceutical, the [18F] LBT-999No drug interventionsdiagnostic0terminated
NCT01215227
An Active-Controlled Extension Study to NCT01155466 [P04938] and NCT01227265 [P07037] (P06153)treatment3terminated
NCT00160576
Levetiracetam Treatment in Adult Subjects With Parkinson's Disease Experiencing Troublesome DyskinesiasNot Available2completed
NCT01860794
Evaluation of Safety and Tolerability of Fetal Mesencephalic Dopamine Neuronal Precursor Cells for Parkinson's DiseaseNo drug interventionstreatment1 / 2unknown_status
NCT02960464
tDCS for Treatment of Depression in Parkinson's DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT01272687
Study to Determine Mutations in the Gaucher Gene in Patients With Idiopathic Parkinson's Disease for Phenotype-genotype CorrelationNo drug interventionsNot AvailableNot Availablecompleted
NCT02445651
Physiological Effects of Nutritional Support in Patients With Parkinson's DiseaseNo drug interventionssupportive_careNot Availablecompleted
NCT03782753
Molecular Pathology and Neuronal Networks in LRRK2 Parkinson's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT05110547
Multicenter Study of Blood Biomarkers of Mitochondrial and Peroxisomal Metabolism to Differentiate Idiopathic Parkinson's Disease From Related ConditionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03051607
Safety and Tolerability of Tozadenant as Adjunctive Therapy in Levodopa-Treated Patients With Parkinson's Disease.treatment3terminated
NCT04459052
FDOPA PET and Nutritional Support in Parkinson's DiseaseNo drug interventionsdiagnostic2active_not_recruiting
NCT04101513
The Natural History of Parkinson's Disease-associated Spinal DisordersNo drug interventionsNot AvailableNot Availablewithdrawn
NCT00437125
Study on the Tolerability of Duloxetine in Depressed Patients With Parkinson's Diseasetreatment4completed
NCT04202757
Intravenous Plasma Treatment for Parkinson's DiseaseNo drug interventionstreatment0completed
NCT01227265
Placebo Controlled Study of Preladenant in Participants With Moderate to Severe Parkinson's Disease (P07037)treatment3completed
NCT06556173
Phase 2a Study of VTX3232 in Parkinson's DiseaseNo drug interventionstreatment2recruiting
NCT03841604
Effect of Safinamide on Parkinson's Disease Related Chronic Paintreatment4completed
NCT02373072
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of PF-06649751 in Subjects With Idiopathic Parkinson's Diseasebasic_science1completed
NCT02780895
Parkinsonian Brain Repair Using Human Stem CellsNo drug interventionstreatment1unknown_status
NCT03095690
Volumetric Bone Mineral Density and it's Relationship With Osteoporotic Fractures in Parkinson's DiseaseNo drug interventionsotherNot Availablecompleted
NCT00505687
An Open-Label Extension Trial to Assess the Safety and Tolerability of Long Term Treatment of Rotigotine in Subjects With Idiopathic Parkinson's Diseasetreatment3completed
NCT02242487
Twelve Month Safety and Efficacy Study of CVT-301 In Parkinson's Disease Patients With OFF Episodestreatment3completed
NCT00605683
MOTION, Safinamide in Early IPD, as add-on to Dopamine Agonisttreatment3completed
NCT03665493
Dopamine Effect on Inhibitory ControlNo drug interventionsbasic_scienceNot Availablecompleted
NCT01668407
Robot Walking Rehabilitation in Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01606670
Observational Study With Neupro® to Evaluate the Patient´s Perception of Pain Associated With Parkinson´s DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT05687799
Fatigue, Sleep and Quality of Life in Parkinson's PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01970813
Efficacy of Acupuncture and Bee Venom Acupuncture on Patients With Idiopathic Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT05671341
Comparison of Balance, Activity-specific Balance Confidence and Quality of Life in Parkinson's PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00400634
Double-Blind, Multicenter, Sham Surgery Controlled Study of CERE-120 in Subjects With Idiopathic Parkinson's Diseasetreatment2completed
NCT00498758
The APOS System: Effects on Gait, Mobility and QOL in Patients With Parkinson's DiseaseNo drug interventionstreatment2unknown_status
NCT01617135
Safety, Pharmacokinetics and Efficacy Study of CVT-301 Inpatients With Parkinson's Disease and "Off" Episodestreatment2completed
NCT02352363
Randomized Safety Study of CVT-301 Compared to an Observational Control Grouptreatment3completed
NCT01028586
MOTION, Safinamide in Early Idiopathic Parkinson's Disease (IPD), as add-on to Dopamine Agonist (Extension of Trial 27918)treatment3terminated
NCT00279825
Comparison of IPX054, IR Carbidopa-Levodopa, and CR Carbidopa-Levodopa in Subjects With Parkinson's Diseasetreatment2completed
NCT00869830
The Effectiveness of Biofeedback Treatment in Constipated Patients With Idiopathic Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT04524182
The Acute Effect of Lumbosacral Mobilization in Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01968031
A 12-week Randomized Study to Evaluate Oral Istradefylline in Subjects With Moderate to Severe Parkinson's Diseasetreatment3completed
NCT05107531
Investigation of Gait, Foot Pressure Distribution and Balance in Parkinson's Patients With Motor FreezingNo drug interventionsNot AvailableNot Availablecompleted
NCT00115427
Study of Liatermin (r-metHuGDNF) Administered by Bilateral Intraputaminal (IPu) Infusion to Subjects With Idiopathic Parkinson's Diseasetreatment1completed
NCT00627640
Safinamide in Idiopathic Parkinson's Disease (IPD) With Motor Fluctuations, as add-on to LevodopaNo drug interventionstreatment3completed
NCT00125567
Stalevo in Early Wearing-Off Patientstreatment4completed
NCT02525367
Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive TherapyNo drug interventionstreatmentNot Availableterminated
NCT01523301
Rotigotine Versus Placebo to Evaluate the Efficacy on Depressive Symptoms in Idiopathic Parkinson's Disease Patientstreatment4completed
NCT03074812
Exploring Mechanisms for Neuropsychiatric Symptoms of Parkinson Disease Using Transcranial Direct Current StimulationNo drug interventionstreatmentNot Availablerecruiting
NCT00663312
Impact of Deep Brain Stimulation of Subthalamic Nucleus on the Hepatic Glucose Production in Parkinson's DiseaseNo drug interventionsdiagnosticNot Availableterminated
NCT02801110
PET/MR Imaging in Patients With Short and Long Standing Parkinson's DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT01815281
Foot Mechanical Stimulation for Treatment of Gait and Gait Related Disorders in Parkinson's Disease and Progressive Supranuclear Palsy.No drug interventionstreatmentNot Availableterminated
NCT02227355
Evaluating the Effectiveness of Neupro® (Rotigotine) and L-dopa Combination Therapy in Patients With Parkinson's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT04524143
The Acute Effect of Cervical Mobilization in Parkinson's DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT01330290
Caregivers' and Physicians' Treatment Preference in Parkinson Patients Treated With Neupro® Requiring Caregiver SupportNot AvailableNot Availablecompleted
NCT00239564
Pharmacokinetics and Pharmacodynamics of IPX054 in Subjects With Parkinson's DiseaseNo drug interventionstreatment1 / 2completed
NCT01007864
Influence of Piribedil (Clarium®) on Vigilance and Cognitive Function in Patients With Parkinson's Disease Compared to Other Non-Ergot Dopamine Agoniststreatment3completed
NCT02339064
Infusion of Apomorphine: Long-term Safety Studytreatment3active_not_recruiting
NCT02710487
Sleep, Awake & Move - Part IINo drug interventionsotherNot Availablecompleted
NCT01789047
Topiramate as an Adjunct to Amantadine in the Treatment of Dyskinesia in Parkinson's Diseasetreatment2terminated
NCT00243945
A Trial to Evaluate the Effects of Rotigotine Transdermal Patch on Early Morning Motor Impairment and Sleep Disorders Idiopathic Parkinson's Diseasetreatment3completed
NCT00643045
Safinamide as Add-On Therapy in Patients With Early Idiopathic Parkinson's Disease Treated With a Stable Dose of a Single Dopamine Agonisttreatment3completed
NCT02565628
PF-06669571 In Subjects With Idiopathic Parkinson's DiseaseNo drug interventionsbasic_science1completed
NCT01026428
A Study to Assess the Effect of Safinamide on Levodopa PharmacokineticsNot Available1 / 2completed
NCT05094011
Evaluating Safety, Tolerability, and Efficacy of Autologous MitoCell Transplantation in Subjects With Idiopathic Parkinson's DiseaseNo drug interventionstreatment1not_yet_recruiting
NCT01470859
The Effect of Pramipexole on Metabolic Network Activity Compared With Levodopa in Early Parkinson's DiseasetreatmentNot Availablecompleted
NCT01300819
Placebo-controlled Study in Patients With Parkinson's Disease to Evaluate the Effect of Rotigotine on Non-motor Symptomstreatment4completed
NCT00985517
Safety and Efficacy of CERE-120 in Subjects With Parkinson's Diseasetreatment1 / 2completed
NCT02306863
Whole-body Vibration as a Treatment for Parkinson's DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT02453386
Safety and Efficacy Study of Tozadenant to Treat End of Dose Wearing Off in Parkinson's Patientstreatment3terminated
NCT01782222
Trial to Evaluate The Efficacy Of Rotigotine on Parkinson's Disease-Associated Motor Symptoms And Apathytreatment4completed
NCT02240030
Efficacy and Safety Study of CVT-301 In Parkinson's Disease Patients With OFF Episodestreatment3completed
NCT01221948
Vercise Implantable Stimulator for Treating Parkinson's DiseaseNo drug interventionstreatment2completed
NCT00664157
Facial Expression Recognition of Emotion and Categorization of Emotional Words in Parkinson's Disease. Impact of L-Dopa and Deep Brain Stimulation of Subthalamic NucleusNo drug interventionsdiagnosticNot Availablecompleted
NCT02045420
Vascular Abnormalities in Idiopathic Parkinson's DiseaseNo drug interventionsNot AvailableNot Availableunknown_status
NCT02610231
Long Term Study of Istradefylline in Subjects With Moderate to Severe Parkinson's Diseasetreatment3completed
NCT01159691
Change in Gastrointestinal Complaints After Switch From Oral Parkinson's Disease Treatment to Neupro® Transdermal PatchNo drug interventionsNot AvailableNot Availablecompleted
NCT03065192
Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson's DiseaseNo drug interventionstreatment1completed
NCT00873392
Efficacy of Transdermal Nicotine, on Motor Symptoms in Advanced Parkinson's Diseasetreatment2completed
NCT01646268
Rotigotine Versus Placebo As Double Blind Study To Evaluate The Efficacy In Early Stage Idiopathic Parkinson's Disease Patientstreatment3completed
NCT00148369
A Multi-Center, Observational Safety Registry of Subjects With Idiopathic Parkinson's Disease Previously Treated With Intraputaminal Infusion of LiaterminNo drug interventionsNot AvailableNot Availablecompleted
NCT00261781
Walking Capacity in Parkinson's Disease (PD-Walk)No drug interventionstreatmentNot Availableterminated
NCT05691114
Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson's DiseaseNo drug interventionstreatment1recruiting
NCT01646255
Rotigotine Versus Placebo, A Study To Evaluate The Efficacy In Advanced Stage Idiopathic Parkinson's Disease Patientstreatment3completed
NCT01777555
Efficacy and Safety Study of Inhaled CVT 301 in Parkinson's Disease Patients for Treatment of OFF Episodestreatment2completed