NCT06625515
First-in-Human Study of ATX-559, an Oral Inhibitor of DHX9, in Patients with Advanced or Metastatic Solid Tumors, and Molecularly Defined Cancers No drug interventions treatment 1 not_yet_recruiting NCT06631443
Asian Watch-and-Wait Database (AWWD) No drug interventions Not Available Not Available not_yet_recruiting NCT06328361
Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer No drug interventions treatment Not Available recruiting NCT06569368
A Phase II Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy treatment 2 recruiting NCT04814784
Role of Neoadjuvent Radiotherapy in Locally Advanced Cancer Rectum No drug interventions Not Available Not Available unknown_status NCT04349384
Audit of Surgery for Colorectal Cancer No drug interventions Not Available Not Available completed NCT02107105
Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer No drug interventions Not Available Not Available recruiting NCT04963283
Study of Cabozantinib and Nivolumab in Refractory Metastatic Microsatellite Stable (MSS) Colorectal Cancer treatment 2 active_not_recruiting NCT02407561
Prospective Validation Study for the Proprietary Rectal and Anal Cancer Protein Expression Assays No drug interventions Not Available Not Available terminated NCT05108428
Adaptive Radiation for Locally Advanced Rectal Adenocarcinoma treatment 0 active_not_recruiting NCT02919878
Neo-adjuvant Chemoradiotherapy Using Infusional Gemcitabine Followed by Surgery for Locally Advanced Rectal Cancer treatment 2 unknown_status NCT02017509
Immunoscore in Rectal Cancer No drug interventions Not Available Not Available completed NCT01887509
Evaluation of Rectal Tumor Margin Using Confocal Endomicroscopy and Comparison to Histopathology No drug interventions diagnostic Not Available terminated NCT02935309
Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma treatment 1 completed NCT02921256
Veliparib, Pembrolizumab, and Combination Chemotherapy in Treating Patient With Locally Advanced Rectal Cancer treatment 2 completed NCT00321685
Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer treatment 2 completed NCT01634685
A Phase I Study of Bavituximab, Capecitabine, and Radiation for the Treatment of Rectal Adenocarcinoma treatment 1 completed NCT06266832
The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma treatment 2 recruiting NCT01554059
Neoadjuvant Chemoradiation With Bevacizumab for Chinese Rectal Cancer Patients treatment 2 completed NCT05872334
The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery No drug interventions prevention Not Available completed NCT05672524
A Study of Tucatinib and Trastuzumab in People With Rectal Cancer treatment 2 recruiting NCT05081024
Establishing a ctDNA Biomarker to Improve Organ Preserving Strategies in Patients With Rectal Cancer No drug interventions Not Available Not Available recruiting NCT01702116
Extralevator Versus Standard Abdominoperineal Resection For Rectal Adenocarcinoma No drug interventions treatment Not Available unknown_status NCT01619696
Prospective Pilot Study of Multimodal Radiological Evaluation Feasibility During Chemoradiotherapy of Rectal Adenocarcinomas No drug interventions diagnostic 2 terminated NCT03436563
M7824 in Patients With Metastatic Colorectal Cancer or With Advanced Solid Tumors With Microsatellite Instability treatment 1 / 2 active_not_recruiting NCT02368886
Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer treatment 2 completed NCT03799939
Chimney Trial of Parastomal Hernia Prevention No drug interventions prevention Not Available active_not_recruiting NCT04406857
Testing the Addition of a Radiation Sensitizing Drug, IPdR, to the Usual Chemotherapy Treatment (Capecitabine) During Radiation Therapy for Rectal Cancer treatment 1 terminated NCT01497457
Interest of Saline MR Peritoneography for Pre-operative Assessment of Rectal Cancer No drug interventions diagnostic Not Available completed NCT02314182
GRECCAR 8: Primary Tumor Resection in Rectal Cancer With Unresectable Metastasis other 3 completed NCT03365882
S1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by Surgery treatment 2 active_not_recruiting NCT02287727
Regorafenib in Reducing Recurrence in Patients With Non-metastatic Rectal Cancer Who Have Completed Curative-Intent Treatment treatment 2 withdrawn NCT03961776
Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems No drug interventions Not Available Not Available recruiting NCT06524362
Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial No drug interventions supportive_care Not Available not_yet_recruiting NCT03300544
Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer treatment 1 terminated NCT04281667
Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery No drug interventions prevention 4 active_not_recruiting NCT04703101
Short Course Radiation Therapy and Combination Chemotherapy for the Treatment of Stage II-III Rectal Cancer treatment 1 recruiting NCT03619668
Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment No drug interventions Not Available Not Available active_not_recruiting NCT00855946
Proteomic Approach Using Matrix-assisted Laser Desorption/Ionization Tandem Time-of-flight (MALDI-TOF/TOF) of Tumor Response in Rectal Carcinoma After Radiochemotherapy No drug interventions Not Available Not Available completed NCT02688712
ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer treatment 2 active_not_recruiting NCT04090450
Optimisation of Radiotherapy in Rectal Cancer (ORREC) No drug interventions Not Available Not Available unknown_status NCT02575508
Pan FGFR Kinase Inhibitor BGJ398 and Combination Chemotherapy in Treating Patients With Untreated Metastatic Pancreatic Cancer treatment 1 / 2 withdrawn NCT05969938
Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology No drug interventions Not Available Not Available recruiting NCT03871790
Peptide-based Immunization for Colon- and and Pancreas-carcinoma No drug interventions Not Available Not Available completed NCT03527784
Prestoma-Trial for Parastomal Hernia Prevention No drug interventions prevention Not Available terminated NCT06050447
Factors Affecting the Results of Treatment of Patients With Colorectal Cancer No drug interventions Not Available Not Available recruiting NCT02863107
Young-Onset Colorectal Cancer No drug interventions Not Available Not Available active_not_recruiting NCT04621370
A Trial of Durvalumab (MEDI 4736) in Combination With Extended Neoadjuvant Regimens in Rectal Cancer treatment 2 not_yet_recruiting NCT03899870
Factors Predicting Recurrence in Rectal Cancer After Surgery No drug interventions Not Available Not Available completed NCT02270606
Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer treatment 1 completed NCT05482516
Evaluating Novel Therapies in ctDNA Positive GI Cancers treatment 3 recruiting NCT04104139
TAS-102 With Concurrent Radiation for the Treatment of Untreated Resectable Stage II-III Rectal Cancer treatment 1 recruiting NCT03594630
Active Surveillance and Chemotherapy Before Surgery in Treating Participants With Stage II-III Rectal Cancer No drug interventions treatment 0 recruiting NCT04441580
Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting No drug interventions screening Not Available recruiting NCT02319304
Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma treatment 2 terminated NCT04165772
Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors treatment 2 recruiting NCT01047969
Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy No drug interventions treatment 2 unknown_status NCT03297710
TAS-102 and Radiation Therapy in Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, or Cannot Be Removed by Surgery treatment 1 completed NCT02233595
Evaluation of Rectal Cancer Treatment Response Using PET/MRI No drug interventions Not Available Not Available terminated NCT04418895
Neoadjuvant Therapy for Localized Rectal Adenocarcinoma treatment 2 withdrawn NCT05746195
Optimization of Adaptive Text Messages for Cancer Survivors (OATS II) No drug interventions supportive_care Not Available recruiting NCT02393755
Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer treatment 1 / 2 completed NCT04808323
MRI-Guided Adaptive Radiation Therapy for Organ Preservation in Rectal Cancer treatment 1 recruiting NCT02979470
Study of Blood Components as Probable Prognostic and Predictive Markers of Response to Treatment in Advanced Colon and Rectal Cancers No drug interventions Not Available Not Available unknown_status NCT02849158
Fibroblast Before and After Neoadjuvant Chemo-radiotherapy in Patient With Locally Advanced Rectal Adenocarcinoma No drug interventions diagnostic Not Available completed NCT01674309
First Line Treatment by FOLFIRINOX for Patients With a Rectum Cancer With Synchronous Non Resectable Metastasis No drug interventions treatment 2 completed NCT02890758
Phase I Trial of Universal Donor NK Cell Therapy in Combination With ALT803 treatment 1 completed NCT02161822
Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients treatment 2 unknown_status NCT00145769
A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum No drug interventions treatment 3 completed NCT01703910
Study of Individualized Therapies Selection for Patients With Metastatic Colorectal Carcinoma According to the Therapeutic treatment 2 completed NCT06637462
A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer No drug interventions diagnostic Not Available recruiting NCT01037790
Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer treatment 2 completed NCT00551421
Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer treatment 1 / 2 completed NCT03303547
Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits No drug interventions treatment Not Available recruiting NCT00303628
Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer treatment 3 terminated NCT00397878
AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer treatment 2 terminated NCT00052585
Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer treatment 2 terminated NCT00025337
Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated treatment 3 completed NCT00003799
Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer treatment 1 completed NCT00307736
Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer treatment 1 / 2 completed NCT04554836
MoLiMoR - A Study With FOLFIRI-based First-line Therapy With or Without Intermittent Cetuximab treatment 2 active_not_recruiting NCT04005118
Human Intestinal Microbiome and Surgical Outcomes in Patients Undergoing Colorectal Cancer Surgery No drug interventions Not Available Not Available unknown_status NCT00005818
SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer treatment 1 / 2 completed NCT00100841
Phase II Trial of FOLFOX6, Bevacizumab and Cetuximab in Patients With Colorectal Cancer treatment 2 completed NCT00026234
Hepatic Arterial Infusion Plus Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver treatment 2 completed NCT00028496
Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer treatment 1 completed NCT02945566
Can we Save the Rectum by Watchful Waiting or TransAnal Surgery Following (Chemo)Radiotherapy Versus Total Mesorectal Excision for Early REctal Cancer? other 2 / 3 recruiting NCT05080673
Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps No drug interventions other Not Available recruiting NCT00433576
Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery treatment 1 completed NCT00707889
Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer treatment 2 completed NCT04668872
Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation No drug interventions Not Available Not Available recruiting NCT00032110
Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer treatment 2 completed NCT04624555
The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors No drug interventions Not Available Not Available recruiting NCT02046538
Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal Cancer treatment 2 withdrawn NCT01282502
Midostaurin (PKC412) for Locally Advanced Rectal Cancer treatment 1 completed NCT00397384
Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer treatment 1 completed NCT00023933
Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Recurrent or Persistent Metastatic Colorectal Cancer treatment 1 completed NCT02425683
Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX treatment 2 terminated NCT03871959
Pembrolizumab In Combination With Debio 1143 In Pancreatic and Colorectal Advanced/Metastatic Adenocarcinoma treatment 1 completed NCT00052559
Bevacizumab, Fluorouracil, and External-Beam Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer treatment 1 completed NCT01037049
Optimum Timing for Surgery After Pre-operative Radiotherapy 6 vs 12 Weeks No drug interventions other 2 unknown_status NCT00070122
Combination Chemotherapy and Bevacizumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Colorectal Cancer treatment 3 terminated NCT01294826
Study of AUY922 and Cetuximab in Patients With KRAS Wild-Type Metastatic Colorectal Cancer treatment 1 completed NCT00942266
Vorinostat, Fluorouracil, and Leucovorin Calcium in Treating Patients With Metastatic Colorectal Cancer That Has Not Responded to Previous Treatment treatment 2 completed NCT00003873
Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer treatment 3 completed NCT00006094
Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum treatment 1 / 2 completed NCT02641691
Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum treatment 2 completed NCT01340755
Laparoscopy-Assisted Transanal Endoscopy Rectosigmoid Resection for Rectal Cancer No drug interventions treatment Not Available completed NCT01270438
Combination Chemotherapy and Bevacizumab With or Without RO4929097 in Treating Patients With Metastatic Colorectal Cancer treatment 2 withdrawn