Catamenial Epilepsy (DBCOND0037278)

Identifiers

Synonyms

Catamenial epilepsy / Menstrual epilepsy (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Clobazam	A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.	Cytochrome P450 2C19enzyme Cytochrome P450 3A4enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C18enzyme ATP-dependent translocase ABCB1transporter GABA(A) Receptortarget Cytochrome P450 2D6enzyme GABA(A) Receptor Benzodiazepine Binding Sitetarget Albumincarrier Alpha-1-acid glycoprotein 1carrier Cytochrome P450 2C9enzyme UDP-glucuronosyltransferase 1A4enzyme UDP-glucuronosyltransferase 1-6enzyme UDP-glucuronosyltransferase 2B4enzyme UDP-glucuronosyltransferase 1A1enzyme Cytochrome P450 1A2enzyme Cytochrome P450 2C8enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme Gamma-aminobutyric acid receptor subunit alpha-1target Gamma-aminobutyric acid receptor subunit gamma-3target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00559169	Verapamil and Catamenial Epilepsy	Verapamil	treatment	Not Available	withdrawn
NCT05201703	Fycompa in Catamenial Epilepsy	Perampanel	treatment	4	terminated
NCT02426047	Medium Chain Triglycerides as an Adjunct to the Modified Atkins Diet for Women With Catamenial Epilepsy	No drug interventions	treatment	Not Available	completed
NCT00465517	A Randomized, Controlled Trial of Ganaxolone in Adult Uncontrolled Partial-Onset Seizures	Ganaxolone	treatment	2	completed