Cocaine Related Disorders (DBCOND0037604)

Identifiers

Synonyms

Cocaine-Related Disorder / Cocaine-Related Disorders / Cocaine related disorders / Cocaine use, unspecified / Organic mental disorder caused by cocaine (disorder)

Associated Data

Indicated Drugs and Targets

Not Available

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT00535002	The Effect of Yohimbine on Cocaine Cue Reactivity	Yohimbine	treatment	2	completed
NCT00613015	Stress and Medication Effects on Cocaine Cue Reactivity	Guanfacine Modafinil	other	2	completed
NCT01148992	Interactions Between Intravenous (IV) Cocaine and Lofexidine	Lofexidine	treatment	1	terminated
NCT01815645	Contingency Management Treatment for Crack Addiction - Study With Brazilian Population	No drug interventions	treatment	Not Available	completed
NCT01189578	Brain Imaging of Cocaine Craving in Recreational Cocaine Users	No drug interventions	Not Available	Not Available	completed
NCT00946660	Non-Treatment Study of Factors Affecting Cocaine Drug Choice	No drug interventions	Not Available	Not Available	completed
NCT00495092	Efficacy of Caffeine, With and Without Biperiden, in the Detoxification of Cocaine Dependent Patients	Biperiden Caffeine	treatment	2 / 3	completed
NCT01392092	Effects of N-acetylcysteine on Brain Chemistry and Behavior in Cocaine Abusers (NAC)	No drug interventions	Not Available	Not Available	completed
NCT01337297	Prefrontal Cortex Stimulation as Treatment for Crack-cocaine Addiction	No drug interventions	treatment	1 / 2	completed
NCT03242928	Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)	Mavoglurant	treatment	2	completed
NCT00580827	Clinical Efficacy of Disulfiram in LAAM-Maintained Cocaine Abusers	Disulfiram	treatment	Not Available	completed
NCT00000290	Stress Hormones and Human Cocaine Use - 7	Cocaine	treatment	1	completed
NCT00430690	Acoustic Startle Reduction In Cocaine Dependence	No drug interventions	Not Available	Not Available	completed
NCT00514202	Pilot Study Examining Effect for Dextroamphetamine to Treat Cocaine Dependence Plus Attention-deficit Hyperactivity Disorder (ADHD)	Dextroamphetamine	treatment	2	terminated
NCT00089687	GBR 12909 Study in Cocaine Experienced African American Volunteers - 1	Vanoxerine	treatment	1	unknown_status
NCT00000287	Relapse Patterns in Female Cocaine Users - 4	No drug interventions	Not Available	Not Available	completed
NCT00000333	Evaluation of Benztropine for Cocaine Craving - 2	Benzatropine	treatment	2	completed
NCT00000277	Mazindol for Cocaine Abuse - 2	Mazindol	treatment	2	completed
NCT00000245	Evaluation of a Desipramine Ceiling in Cocaine Abuse - 1	Desipramine	treatment	2	completed
NCT00000198	Piracetam for Treatment of Cocaine Addiction - 3	Piracetam	treatment	1	completed
NCT03902405	Computerized Exercise to Alter Stimulant Approach Responses	No drug interventions	treatment	Not Available	unknown_status
NCT00000305	Amphetamine Cocaine Interaction Study - 2	Dextroamphetamine	treatment	1	terminated
NCT00000197	Propranolol for Treatment of Cocaine Addiction - 2	Propranolol	treatment	2	completed
NCT00217997	Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals	No drug interventions	Not Available	Not Available	completed
NCT00142883	The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3	Pregabalin	treatment	Not Available	terminated
NCT00249483	Venlafaxine to Reduce Cocaine Dependence in Depressed Individuals	Venlafaxine	treatment	2	completed
NCT00033111	A Study of Cabergoline for the Treatment of Cocaine Dependence - 1	Cabergoline	treatment	2	completed
NCT00000211	Treatment Efficacy for Drug Abuse and AIDS Prevention - 2	Buprenorphine	treatment	2	completed
NCT03556371	Evaluation of N-Acetylcysteine Efficacy to Reduce the Craving and to Prolong Abstinence Time of Coca Paste	Acetylcysteine	treatment	2	completed
NCT00000278	Disulfiram for Cocaine-Alcohol Abuse - 3	Disulfiram	treatment	2	completed
NCT00033085	Ondansetron for the Treatment of Cocaine Dependence - 1	Ondansetron	treatment	2	completed
NCT00082485	Baclofen for the Treatment of Cocaine Dependence - 1	Baclofen	treatment	2	completed
NCT00000285	Effects of Phenytoin on Cocaine Use in Humans - 2	Phenytoin	treatment	1	completed
NCT00129285	Modafinil Treatment for Cocaine-Dependent Individuals	Modafinil	treatment	2	completed
NCT00094315	Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1	Cocaine	Not Available	1	unknown_status
NCT00000332	High Dose Nimodipine Treatment Adjunct - 1	Nimodipine	treatment	2	completed
NCT04155632	Neurocircuit Strategy to Decrease Cocaine Cue Reactivity	Acetylcysteine	basic_science	2	active_not_recruiting
NCT00015132	Tiagabine, Sertraline, or Donepezil for the Treatment of Cocaine Dependence - 9	Sertraline	treatment	2	completed
NCT00158132	Effectiveness of Amantadine and Propranolol for Treating Cocaine Dependence - 2	Amantadine Propranolol	treatment	2	completed
NCT00100100	Modafinil for the Treatment of Cocaine Dependence - 1	Modafinil	diagnostic	2	completed
NCT00000200	Cocaine Effects in Humans: Physiology and Behavior - 1	Methadone	treatment	2	completed
NCT00015275	Pathophysiological Subtyping of Abnormalities in Cocaine Dependence - 9	No drug interventions	diagnostic	4	completed
NCT00000275	Cocaine Abuse and ADHD - 10	Flupentixol	treatment	2	completed
NCT00218075	Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence	Carbidopa Levodopa	treatment	2	completed
NCT00000270	Brain Imaging: Cocaine Effects & Medication Development - 5	Cocaine	treatment	4	withdrawn
NCT00015106	Resperine, Gabapentin, or Lamotrigine for the Treatment of Cocaine Dependence: 2 - 7	Lamotrigine	treatment	2	completed
NCT00218049	Interaction Between Vanoxerine (GBR 12909) and Cocaine in Cocaine Dependent Individuals	Vanoxerine	treatment	1	terminated
NCT00015249	Prepulse Inhibition of Startle in Cocaine Dependence - 7	Amantadine	diagnostic	1	completed
NCT00000349	Infusion Laboratory: Protocol 5 (Flupenthixol) - 14	Flupentixol	treatment	1	unknown_status
NCT00000336	Selegiline in Outpatient Treatment for Cocaine Dependence - 1	Selegiline	treatment	2	completed
NCT00015236	Modeling Impaired Judgement in Cocaine Abusers - 6	No drug interventions	prevention	4	completed
NCT00232336	Quetiapine for Cocaine Use and Cravings	Quetiapine	treatment	4	completed
NCT00100113	Assessment of Potential Interactions Between GBR 12909 and Cocaine - 1	Vanoxerine	treatment	1	unknown_status
NCT00000218	Pharmacotherapy and Intensive Treatment - 2	Carbamazepine	treatment	4	completed
NCT00142818	Modafinil and Naltrexone to Reduce Cocaine and Alcohol Dependence	Modafinil Naltrexone	treatment	2	completed
NCT00000317	Early Phase II Trials for Cocaine Medication Development - 1	Risperidone	treatment	2	completed
NCT00396734	The Effects of Pharmacotherapy on Brain Mechanisms Underlying Cocaine Dependence.	Modafinil Topiramate	treatment	Not Available	suspended
NCT00000324	Tryptophan and Behavior Therapy for Cocaine Abuse - 1	Tryptophan	treatment	2	completed
NCT00067535	Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1	Cocaine	diagnostic	1	completed
NCT00218348	Treatment of Cocaine Dependence: Comparison of Three Doses of Dextro-Amphetamine Sulfate and Placebo	Sulfate ion	treatment	2	completed
NCT00000348	Infusion Laboratory: Protocol 4 (Dihydrexidine) - 13	Dihydrexidine	treatment	1	unknown_status
NCT00218257	Progesterone for the Treatment of Cocaine Dependence - 1	Progesterone	treatment	Not Available	completed
NCT02037126	Psilocybin-facilitated Treatment for Cocaine Use	Diphenhydramine Psilocybin	treatment	2	completed
NCT00223626	Topiramate to Reduce Cocaine Dependence	Topiramate	basic_science	2	completed
NCT00265265	Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1	Atomoxetine	treatment	1	completed
NCT00276874	Aripiprazole to Reduce Cocaine Relapse	Aripiprazole	treatment	1	completed
NCT00733720	Buprenorphine Naltrexone-P1 A-Cocaine	Buprenorphine Naloxone Naltrexone	treatment	1	completed
NCT03606473	Brain Mechanisms in Young Adults	Dextroamphetamine	basic_science	0	completed
NCT01723527	Diversion to Treatment for Injection Drug Users Arrested for Possession of Heroin	Buprenorphine Methadone	treatment	1	completed
NCT00000276	Dopamine Reuptake Inhibitors of Cocaine Abuse - 1	Bupropion	treatment	1	terminated
NCT03007394	Lorcaserin in the Treatment of Cocaine Use Disorder	Lorcaserin	treatment	2	completed
NCT00249691	Effectiveness of Topiramate in Treating Cocaine Dependent Individuals - 1	Topiramate	treatment	3	unknown_status
NCT00000191	Carbamazepine Treatment for Cocaine Dependence - 5	Carbamazepine	treatment	2	completed
NCT00015080	Naltrexone in Treatment of Cocaine Dependence - 5	Naltrexone	treatment	2	completed
NCT00000280	Glutaminergic Agents for Cocaine Abuse - 5	Nimodipine	treatment	1	completed
NCT00000340	Pemoline in the Treatment of Stimulant Dependence - 5	Pemoline	treatment	2	withdrawn
NCT00000301	Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence - 4	Amantadine	treatment	2	completed
NCT00015301	Methylphenidate Raclopride Positron Emission Tomography (PET) Test - 11	Methylphenidate	diagnostic	4	completed
NCT00000201	Pharmacological Modulation of Cocaine Effects - 1	Selegiline	treatment	2	completed
NCT00000304	Dextroamphetamine as an Adjunct in Cocaine Treatment - 1	Dextroamphetamine	treatment	2	completed
NCT00000268	Cocaine Abuse and Attention Deficit Disorder - 3	Bupropion	treatment	Not Available	completed
NCT00149669	Employment-based Reinforcement of Naltrexone Ingestion and Abstinence	No drug interventions	treatment	Not Available	completed
NCT00000269	Pergolide Treatment for Substance Abusers - 4	Pergolide	treatment	2	completed
NCT00000312	Alterations in Serotonergic Functions in Cocaine Addicts - 1	m-Chlorophenylpiperazine	treatment	1	completed
NCT03953612	The Role of Neuroactive Steroids in Stress, Drug Craving and Drug Use in Cocaine Use Disorders	Pregnenolone	treatment	0	completed
NCT00292110	Treatment of Heroin and Cocaine With Methadone Maintenance and Contingency Management	Methadone	treatment	1	completed
NCT00000210	Treatment Efficacy for Drug Abuse and AIDS Prevention - 1	Buprenorphine	treatment	2	completed
NCT00000281	Pharmacotherapy for Schizophrenic Drug Users - 6	No drug interventions	treatment	2	completed
NCT00000314	M-CPP and Fenfluramine in Cocaine Addicts - 3	m-Chlorophenylpiperazine	treatment	2	completed
NCT00086255	Tiagabine for the Treatment of Cocaine Dependence - 1	Tiagabine	treatment	2	completed
NCT00015223	Methylphenidate in the Treatment of Cocaine Dependent Patients With Adult Attention Deficit Hyperactivity Disorder - 5	Methylphenidate	treatment	2	completed
NCT02986438	Treatment With Transcranial Magnetic Stimulation for Cocaine Addiction: Clinical Response and Functional Connectivity.	No drug interventions	treatment	Not Available	unknown_status
NCT01526538	Improving Learning-based Treatment of Cocaine Dependence With Medication	Cycloserine	treatment	2	completed
NCT00218543	Atomoxetine for Treating Cocaine Abuse in Adults With Attention Deficit Hyperactivity Disorder (ADHD)	Atomoxetine	treatment	2	completed
NCT00000303	Rapid Evaluation of Baclofen for Treatment of Cocaine Abuse/Dependence - 6	Baclofen	treatment	2	completed
NCT00000190	Cocaine in Parotid Saliva, Blood and Urine - 4	No drug interventions	diagnostic	1	completed
NCT02797990	Conflict Between Maternal Autonomy and Child Health in Substance-use	No drug interventions	Not Available	Not Available	completed
NCT00780702	Aripiprazole for Prevention of Relapse to Cocaine Use in Methadone-Maintenance Patients	No drug interventions	treatment	1	completed
NCT00142779	Fluoxetine to Reduce Cocaine Use in Cocaine and Opioid Addicts	Fluoxetine	treatment	Not Available	completed
NCT00000187	Ritanserin in Treatment of Cocaine Dependence - 1	Ritanserin	treatment	2	completed
NCT00033033	Reserpine for the Treatment of Cocaine Dependence - 1	Reserpine	treatment	2	completed
NCT04306354	Use of Intranasal Oxytocin During Detoxification of Crack Cocaine	Oxytocin	treatment	1 / 2	unknown_status
NCT00015054	Methylphendidate Treatment of Cocaine Dependent Patients With Attention Deficit Hyperactivity Disorder - 3	Methylphenidate	treatment	2	completed
NCT01984177	Effects of Corticorelin Administration on Dopamine Transmission, Craving, and Mood in Cocaine Dependence	Corticorelin	Not Available	Not Available	completed
NCT00000347	Risperidone for Treatment of Cocaine Dependence in Outpatients - 12	Risperidone	treatment	2	completed
NCT00033098	Cocaine-Metyrapone Interaction Study - 1	Metyrapone	treatment	1	unknown_status
NCT00129298	Effectiveness of Tiagabine for Cocaine Dependence in Methadone-Maintained Individuals - 1	Tiagabine	treatment	2	completed
NCT00000311	Combining Behavioral Treatment With Agonist Maintenance - 1	Buprenorphine Methadone	treatment	3	completed
NCT00000293	Effect of Nefazodone on Relapse in Females With Cocaine Abuse - 10	Nefazodone	treatment	3	completed
NCT00000271	New Approaches to Cocaine Abuse Medications (A) - 6	Desipramine	treatment	2	completed
NCT00000188	Selegiline in Treatment of Cocaine Dependence - 2	Selegiline	treatment	2	completed
NCT00000307	Naltrexone as Adjunct in Alcoholic Cocaine Dependent Patients - 4	Naltrexone	treatment	2	completed
NCT00000309	Serotonin/Dopamine Antagonism of Cocaine Effect: 1 - 1	Risperidone	treatment	2	terminated
NCT00000215	IV Cocaine Abuse: A Laboratory Model - 4	Pergolide	treatment	2	completed
NCT00000315	Human Dopamine Transported Imaging in Cocaine Abuse: 1 - 1	Cocaine	treatment	1	completed
NCT00000337	Infusion Laboratory: Protocol 1 - Selegeline - 2	Selegiline	treatment	1	completed
NCT04280900	Benefits of Therapy With Virtual Reality Exposure in the Treatment of Cocaine Use Disorders	No drug interventions	treatment	Not Available	unknown_status
NCT00033059	Assessment of Potential Interactions Between Cocaine and Tolcapone - 1	Tolcapone	treatment	1	unknown_status
NCT00249470	The Therapeutic Workplace Initiation Study	No drug interventions	treatment	Not Available	completed
NCT00000342	Risperidone for the Treatment of Cocaine Dependence - 7	Risperidone	treatment	2	completed
NCT00000242	Carbamazepine Treatment of Cocaine Dependence - 1	Carbamazepine	treatment	2	completed
NCT00000199	Piracetam for Treatment of Cocaine Addiction, Phase II - 4	Piracetam	treatment	1	withdrawn
NCT00000306	Dextroamphetamine as Adjunct in Cocaine/Opiate Dependent Patients - 3	Dextroamphetamine	treatment	2	completed
NCT00000313	Predictive Values of Serotonergic Alterations for Outcome - 2	Fenfluramine	treatment	1	terminated
NCT00000213	IV Cocaine Abuse: A Laboratory Model - 2	Fluoxetine	treatment	2	completed
NCT02915341	Towards Detecting Cocaine Use Using Smartwatches in the NIDA Clinical Trials Network	No drug interventions	Not Available	Not Available	completed
NCT00000217	Pharmacotherapy and Intensive Treatment of Drug Abuse - 1	Carbamazepine	treatment	2	completed
NCT00136734	Methylphenidate Treatment for Cocaine Abuse and ADHD - 1	Methylphenidate	treatment	1	completed
NCT00000316	Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2	Cocaine	treatment	1	completed
NCT00032916	Drug Interaction Study With NS2359 and Cocaine in Cocaine Experienced Volunteers - 1	NS-2359	treatment	1	unknown_status
NCT00000216	Buprenorphine Maintenance for Cocaine Abusing Opioid Addicts - 1	Buprenorphine	treatment	3	completed
NCT00124696	Cocaethylene as a Treatment for Cocaine Dependence - 1	No drug interventions	treatment	1	completed
NCT00051896	Assessment of the Potential Interactions Between Cocaine and GBR 12909 - 1	Vanoxerine	treatment	1	unknown_status
NCT00877435	Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial	No drug interventions	treatment	Not Available	completed
NCT00000286	Effects of Nefazodone on Treatment of Female Cocaine Abusers - 3	Nefazodone	treatment	2	completed
NCT00000339	Infusion Laboratory: Protocol 3 (Risperidone) - 4	Risperidone	treatment	1	unknown_status
NCT00136825	Effectiveness of N-acetylcysteine in Treating Cocaine Dependent Individuals - 1	Acetylcysteine	treatment	1	completed
NCT00000325	Psychostimulant Abuse - Novel Treatment Approaches - 1	No drug interventions	treatment	1	completed
NCT00000248	Dose Response Trial of Pergolide for Cocaine Dependence - 1	Pergolide	treatment	3	completed
NCT00040066	Development of Human Laboratory Study Model of Cocaine Relapse Prevention. - 1	No drug interventions	treatment	1	unknown_status
NCT00000266	Flupenthixol Treatment in Schizophrenic Cocaine Abusers - 1	Flupentixol	treatment	2	completed
NCT00218166	Effectiveness of GABA Agonists in Reducing the Reinforcing Effects of Cocaine	Baclofen Tiagabine Triazolam	treatment	2	completed
NCT00000274	Flupenthixol and Haloperidol for Treating Cocaine Abuse Schizophrenics - 9	Flupentixol	treatment	2	completed
NCT00000282	Pemoline for Cocaine Abuse - 7	Pemoline	treatment	2	completed
NCT03333460	Transcranial Magnetic Stimulation for Cocaine Addiction	No drug interventions	treatment	Not Available	unknown_status
NCT00000294	Effects of Carvedilol on Cocaine Use in Humans - 11	Carvedilol	treatment	2	completed
NCT00000291	Effects of Labetalol on Human Cocaine Use - 8	Labetalol	treatment	2	completed
NCT03986762	Open Label Pharmaco- Magnetic Resonance Spectrography (MRS) Study of Clavulanic Acid	Clavulanic acid	treatment	1	completed
NCT00218062	Effectiveness of Modafinil and D-amphetamine in Treating Cocaine Dependent Individuals	Dextroamphetamine Modafinil	treatment	2	completed
NCT00032929	Selegiline Transdermal System for the Treatment of Cocaine Dependence - 1	Selegiline	treatment	3	completed
NCT00094289	Interactions Between Cocaine and Ethanol and Disulfiram - 1	Disulfiram	treatment	1	unknown_status
NCT00000189	Gepirone vs Placebo in Treatment of Cocaine Dependence - 3	Gepirone	treatment	2	completed
NCT00000292	Acute Withdrawal From Smoked Cocaine - 9	No drug interventions	treatment	1	completed
NCT00142844	Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1	Disulfiram Naltrexone	treatment	2	completed
NCT00000240	Combined Buprenorphine and Behavioral Treatment With and Without Contingent Reinforcement on Opioid and Cocaine Abstinence. - 22	Buprenorphine	treatment	2	completed
NCT00000267	Risperidone Treatment in Dually-Diagnosed Individuals - 2	Risperidone	treatment	2	completed
NCT00015067	Cocaine-Methylphendidate Interaction Study - 4	Methylphenidate	treatment	1	completed
NCT00134901	Effectiveness of Memantine in Treating Cocaine-Dependent Individuals - 2	Memantine	treatment	2	completed
NCT02563769	Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study	Clavulanic acid Cocaine	treatment	1	completed
NCT00033046	Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1	Modafinil	treatment	1	unknown_status
NCT00000212	IV Cocaine Abuse: A Laboratory Model - 1	Desipramine	treatment	2	completed
NCT02896712	Developing Adaptive Interventions for Cocaine Cessation and Relapse Prevention	Modafinil Starch, corn	treatment	2	completed
NCT02773212	Targeting Anhedonia in Cocaine Use Disorder	Dextroamphetamine	treatment	2	completed
NCT00015210	Nefazodone in the Treatment of Cocaine Dependence and Depression - 4	Nefazodone	treatment	2	completed
NCT00000310	Serotonin/Dopamine Antagonism of Cocaine Effect: 2 - 2	Risperidone	treatment	2	terminated
NCT00000214	IV Cocaine Abuse: A Laboratory Model - 3	Buprenorphine	treatment	2	completed
NCT00087750	Interaction Between Cocaine and Quetiapine - 1	Quetiapine	treatment	1	unknown_status
NCT00218023	Medications for Stopping Cocaine Dependence and Preventing Relapse	Carbidopa Levodopa Modafinil Naltrexone	treatment	2	completed
NCT00000323	Therapeutic Potential of Kappa-Opioids Against Cocaine - 1	No drug interventions	Not Available	Not Available	completed
NCT00218608	Disulfiram for Treating Cocaine Dependence in Individuals Maintained on Methadone	Disulfiram	treatment	2	completed
NCT00000308	Dextroamphetamine-Cocaine Behavioral Intervention - 5	Dextroamphetamine	treatment	2	completed
NCT00000338	Infusion Laboratory: Protocol 2 (Lisuride) - 3	Lisuride	treatment	1	unknown_status
NCT03143543	Phase I Functional Magnetic Resonance Imaging (fMRI) Pharmacodynamic Studies of Compounds for Opioid Use Disorder and Cocaine Use Disorder	Lorcaserin	treatment	1	terminated
NCT00000272	New Approaches to Cocaine Abuse Medications (B) - 7	Risperidone	treatment	2	completed