Paroxysmal Nocturnal Haemoglobinuria (PNH)

Also known as: Marchiafava-Micheli Syndrome / Paroxysmal Nocturnal Hemoglobinuria / Paroxysmal Nocturnal Hemoglobinuria (PNH) / Paroxysmal Nocturnal Haemoglobinuria / Haemoglobinuria: [external cause] or [haemolytic] or [paroxysmal nocturnal] / Paroxysmal nocturnal hemoglobinuria (disorder) / (Haemoglobinuria: [March]) or (Marchiafava-Micheli syndrome) / Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]

DrugDrug NameDrug Description
DB01257EculizumabA recombinant humanized monoclonal antibody used to reduce the risk of hemolysis in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
DB16694PegcetacoplanA complement inhibitor indicated in the treatment of adults with paroxysmal nocturnal hemoglobinuria.
DB11580RavulizumabA monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria.
DrugDrug NamePhaseStatusCount
DB11752Bryostatin 11Completed1
DB16694Pegcetacoplan1Completed2
DB00020Sargramostim1Completed1
DB16128Crovalimab1 / 2Active Not Recruiting1
DB00087Alemtuzumab2Completed2
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB16121Cemdisiran2Enrolling by Invitation1
DB16121Cemdisiran2Not Yet Recruiting1
DB00531Cyclophosphamide2Completed2
DB00531Cyclophosphamide2Recruiting1
DB00091Cyclosporine2Completed1
DB00091Cyclosporine2Unknown Status2
DB15401Danicopan2Completed1
DB01257Eculizumab2Active Not Recruiting1
DB01257Eculizumab2Completed2
DB00099Filgrastim2Completed2
DB01073Fludarabine2Completed3
DB01073Fludarabine2Recruiting1
DB16200Iptacopan2Active Not Recruiting1
DB00848Levamisole2Unknown Status2
DB01042Melphalan2Completed2
DB00563Methotrexate2Completed1
DB00075Muromonab2Completed1
DB00688Mycophenolate mofetil2Completed3
DB14991Nomacopan2Completed1
DB14991Nomacopan2Enrolling by Invitation1
DB16694Pegcetacoplan2Recruiting1
DB15218Pozelimab2Active Not Recruiting1
DB15218Pozelimab2Enrolling by Invitation1
DB15218Pozelimab2Not Yet Recruiting1
DB11580Ravulizumab2Active Not Recruiting1
DB00073Rituximab2Completed1
DB00864Tacrolimus2Completed1
DB11926Tesidolumab2Active Not Recruiting1
DB04572Thiotepa2Completed1
DB15636Zilucoplan2Active Not Recruiting1
DB15636Zilucoplan2Completed2
DB16128Crovalimab3Recruiting3
DB15401Danicopan3Recruiting1
DB01257Eculizumab3Active Not Recruiting4
DB01257Eculizumab3Completed6
DB01257Eculizumab3Recruiting3
DB16200Iptacopan3Not Yet Recruiting2
DB16200Iptacopan3Recruiting1
DB14991Nomacopan3Recruiting1
DB16694Pegcetacoplan3Active Not Recruiting1
DB16694Pegcetacoplan3Completed1
DB15218Pozelimab3Enrolling by Invitation1
DB11580Ravulizumab3Active Not Recruiting2
DB11580Ravulizumab3Recruiting2
DB01257Eculizumab4Recruiting1
DB11580Ravulizumab4Recruiting1
DB00877Sirolimus4Not Yet Recruiting1
DB00682Warfarin4Not Yet Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)Not AvailableCompleted1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB01257EculizumabNot AvailableRecruiting1
DB01073FludarabineNot AvailableCompleted1
DB01042MelphalanNot AvailableCompleted1
DB16694PegcetacoplanNot AvailableNo Longer Available1