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Mild Metabolic acidosis
go.drugbank.com/conditions/DBCOND0023722Drugs: Dipotassium phosphate · Gluconic Acid · Lactic acid · Magnesium chloride · Potassium acetate · Potassium chloride +2 moreOmeprazole Action Pathway (old)
smpdb.ca/view/SMP0000226Drug actionThis active metabolite then binds covalently to the potassium-transporting ATPase protein subunits, found at the secretory surface of the gastric parietal cell, preventing any stimulus. … Losec and Zegerid, is a proton pump inhibitor (PPI) class drug that suppresses the final step in gastric acid production, and was the first proton pump inhibitor to e developed.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Metabolic Acidosis
go.drugbank.com/conditions/DBCOND0043658Drugs: Citric acid · Potassium chloride · Potassium citrate · Pyridoxine · Sodium bicarbonate · Sodium chloride +2 moreDehydration Hypertonic
go.drugbank.com/conditions/DBCOND0091314Esomeprazole Action Pathway (Old)
smpdb.ca/view/SMP0000225Drug actionThis active metabolite then binds covalently to the potassium-transporting ATPase protein subunits, found at the secretory surface of the gastric parietal cell, preventing any stimulus. … In this pathway, esomeprazole is taken orally and is oxidized in the stomach to form the active metabolite of esomeprazole.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Pantoprazole Action Pathway
smpdb.ca/view/SMP0000228Drug actionThis active metabolite then binds covalently to the potassium-transporting ATPase protein subunits, found at the secretory surface of the gastric parietal cell, preventing any stimulus. … Because the drug binds covalently, its effects are dose-dependent and last much longer than similar drugs that bind to the protein non-covalently.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Cimetidine Action Pathway
smpdb.ca/view/SMP0000232Drug actionCimetidine also helps to block pepsin and gastrin output, and due to the inhibition of gastric acid secretion, it is typically used to treat heartburn and ulcers. … This blocks histamine effects, resulting in reduced gastric acid secretion and a reduction in gastric volume and acidity.
Enzymes: Chloride intracellular channel protein 2, Potassium-transporting ATPase alpha chain 1Dehydration
go.drugbank.com/conditions/DBCOND0003946Drugs: Calcium chloride · D-glucose · Hyaluronic acid · Potassium chloride · Sodium chloride · Sodium citrate +2 moreUlobetasol
go.drugbank.com/drugs/DB00596ApprovedInvestigational[A215597] Due to its high potency, it is mainly prescribed in the treatment of severe plaque psoriasis and corticosteroid responsive dermatoses.
Categories: tazarotene and ulobetasolIncrease in Intracranial Pressure (ICP)
go.drugbank.com/conditions/DBCOND0113421