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Displaying targets 3526 - 3550 of 6103 in total
TargetOrganismDescription# of Drugs
Mitogen-activated protein kinase 11HumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK11 is...  more7Details
Mitogen-activated protein kinase 12HumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is...  more9Details
Mitogen-activated protein kinase 13HumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is...  more2Details
Mitogen-activated protein kinase 14HumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is...  more77Details
Mitogen-activated protein kinase 15HumansAtypical MAPK protein that regulates several process such as autophagy, ciliogenesis, protein trafficking/secretion a...  more1Details
Mitogen-activated protein kinase 3HumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK...  more9Details
Mitogen-activated protein kinase 4HumansAtypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the c...  more1Details
Mitogen-activated protein kinase 7HumansPlays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream act...  more1Details
Mitogen-activated protein kinase 8HumansSerine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration,...  more17Details
Mitogen-activated protein kinase 9HumansSerine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration,...  more8Details
Mitogen-activated protein kinase kinase (MAPKK)HumansNot Available5Details
Mitogen-activated protein kinase kinase kinase 1HumansComponent of a protein kinase signal transduction cascade. Activates the ERK and JNK kinase pathways by phosphorylati...  more5Details
Mitogen-activated protein kinase kinase kinase 10HumansActivates the JUN N-terminal pathway2Details
Mitogen-activated protein kinase kinase kinase 11HumansActivates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine a...  more2Details
Mitogen-activated protein kinase kinase kinase 12HumansPart of a non-canonical MAPK signaling pathway. Activated by APOE, enhances the AP-1-mediated transcription of APP, v...  more3Details
Mitogen-activated protein kinase kinase kinase 13HumansActivates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PR...  more2Details
Mitogen-activated protein kinase kinase kinase 15HumansSerine/threonine kinase which acts as a component of the MAP kinase signal transduction pathway. Once activated, acts...  more1Details
Mitogen-activated protein kinase kinase kinase 19HumansNot Available2Details
Mitogen-activated protein kinase kinase kinase 2HumansComponent of a protein kinase signal transduction cascade. Regulates the JNK and ERK5 pathways by phosphorylating and...  more4Details
Mitogen-activated protein kinase kinase kinase 20HumansStress-activated component of a protein kinase signal transduction cascade that promotes programmed cell death in res...  more3Details
Mitogen-activated protein kinase kinase kinase 3HumansComponent of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 trans...  more1Details
Mitogen-activated protein kinase kinase kinase 4HumansComponent of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not th...  more1Details
Mitogen-activated protein kinase kinase kinase 5HumansSerine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an ...  more3Details
Mitogen-activated protein kinase kinase kinase 6HumansComponent of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways1Details
Mitogen-activated protein kinase kinase kinase 8HumansRequired for lipopolysaccharide (LPS)-induced, TLR4-mediated activation of the MAPK/ERK pathway in macrophages, thus ...  more2Details
Displaying targets 3526 - 3550 of 6103 in total