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Displaying targets 26 - 50 of 205 in total
G1/S-specific cyclin-D1
Matched Polypeptides specific function: … and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle ... Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional ... Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent …
Serine/threonine protein kinase UL97
Matched Polypeptides specific function: … roles in several processes including nuclear viral egress, viral replication or regulation of host cell cycle ... Stimulates host cell cycle to support viral DNA synthesis by phosphorylating host retinoblastoma/RB1 …
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Matched Polypeptides specific function: … Isoform 2 is involved in the regulation of the contraction/relaxation cycle. …
Chloride intracellular channel protein 1
Matched Polypeptides specific function: … Involved in regulation of the cell cycle. …
Pol polyprotein
Matched Polypeptides specific function: … During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host …
Serine/threonine-protein kinase pim-1
Matched Polypeptides specific function: … cycle progression, CDKN1B, at both transcriptional and post-translational levels. ... oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle ... Phosphorylation of CDKN1A, a regulator of cell cycle progression at G1, results in the relocation of …
3-methylaspartate ammonia-lyase
Matched Polypeptides specific function: … Involved in the methylaspartate cycle. …
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
Matched Polypeptides specific function: … metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle …
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Matched Polypeptides specific function: … Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity) …
Phosphoenolpyruvate Carboxykinases
Matched Polypeptides specific function: … metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle …
Matched Polypeptides general function: … metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle …
Matched Polypeptides general function: … metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle …
Serine/threonine-protein kinase Chk2
Matched Polypeptides specific function: … May also phosphorylate NEK6 which is involved in G2/M cell cycle arrest. ... May also negatively regulate cell cycle progression during unperturbed cell cycles. ... Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation …
Methionine aminopeptidase 1
Matched Polypeptides specific function: … Required for normal progression through the cell cycle. …
Serine/threonine-protein kinase haspin
Matched Polypeptides specific function: … centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle …
Fatty acid oxidation complex subunit alpha
Matched Polypeptides specific function: … Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. …
Elongation of very long chain fatty acids protein 4
Matched Polypeptides specific function: … first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle ... , allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle …
GTP-binding nuclear protein Ran
Matched Polypeptides general function: … Involved in chromatin condensation and control of cell cycle (By similarity). …
Adenylosuccinate synthetase isozyme 1
Matched Polypeptides specific function: … Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide …
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI
Matched Polypeptides specific function: … Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity) …
Methylisocitrate lyase
Matched Polypeptides specific function: … Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate …
Cell division control protein 2 homolog
Matched Polypeptides specific function: … Plays a key role in the control of the eukaryotic cell cycle. …
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
Matched Polypeptides specific function: … Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin …
Acetyl-coenzyme A synthetase 2-like, mitochondrial
Matched Polypeptides specific function: … Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to …
Serine/threonine-protein kinase A-Raf
Matched Polypeptides specific function: … signaling cascade.Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle …
Calcium-dependent protein kinase 4
Matched Polypeptides general function: … Required for cell cycle progression in the male gametocyte, an essential step in parasite transmission …
Cruzipain
Matched Polypeptides specific function: … important role in the development and differentiation of the parasites at several stages of their life cycle …
Displaying targets 26 - 50 of 205 in total