Displaying drugs 126 - 150 of 407 in total
| Name | Weight | Structure | Desription | Categories |
|---|---|---|---|---|
| Evolocumab | 141800.0 C6242H9648N1668O1996S56 |  | A PCSK9 (proprotein convertase subtilisin kexin type 9) inhibitor antibody used as an adjunct to LDL cholesterol reducing therapies, aiding in the prevention of cardiovascular events and cardiovascular revascularization procedures. | Anticholesteremic Agents / Hypolipidemic Agents Indicated for Hyperlipidemia / PCSK9 Inhibitor |
| Asparaginase Erwinia chrysanthemi | 140000.0 C1546H2510N432O476S9 |  | An asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma. | Amidohydrolases / Antineoplastic Agents / Asparagine-specific Enzyme |
| Pancrelipase | 131000.0 |  | A purified form of porcine pancreatic lipase, amylase, and protease enzymes used to treat malabsorption associated with pancreatic insufficiency resulting from cystic fibrosis and pancreatitis. | Enzyme Preparations |
| Albutrepenonacog alfa | 125000.0 C5077N7846O1588PS67 |  | A recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B. | Albumins / Amino Acids, Peptides, and Proteins / Biological Factors / Blood Coagulation Factors / Blood Proteins / Drugs that are Mainly Renally Excreted / Enzyme Precursors / Enzymes and Coenzymes / Hemostatics / Protein Precursors / Proteins / Recombinant Proteins |
| Avalglucosidase alfa | 124000.0 C4490H6818N1197O1299S32 | | A lysosomal glycogen-specific enzyme that is used to treat patients one year of age and older with late-onset Pompe disease, or lysosomal acid alpha-glucosidase (GAA) deficiency. | Enzymes |
| Pegunigalsidase alfa | 116000.0 C2060H3130N552O601S27 | | A recombinant form of human α-galactosidase-A indicated for long-term enzyme replacement therapy in patients with Fabry disease. | Enzymes |
| Aflibercept | 115000.0 C4318H6788N1164O1304S32 | | A vascular endothelial growth factor (VEGF) inhibitor used to treat Neovascular (Wet) Age-Related Macular Degeneration (AMD), various types of macular edema and diabetic retinopathy, and metastatic colorectal cancer | Antineovascularisation Agents |
| Elapegademase | 115000.0 C1797H2795N477O544S12 | | A recombinant adenosine deaminase used to treat adenosine deaminase severe combined immune deficiency. | Adenosine Deaminase Inhibitors |
| Collagenase clostridium histolyticum | 112023.2 C5028H7666N1300O1564S21 |  | A collagenase enzyme used to promote debridement of necrotic tissue in burns and skin ulcers as well as to treat Dupuytren's contracture and Peyronie's disease. | Peptide Hydrolases |
| Elosulfase alfa | 110800.0 C5020H7588N1364O1418S34 |  | A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. | Enzymes / Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme / Polysaccharide-Lyases / Recombinant Proteins / Sulfatases |
| Alglucosidase alfa | 105270.802 C4435H6739N1175O1279S32 |  | An acid alpha- glucosidase (GAA) derivative used as an enzyme replacement therapy for the treatment of Pompe disease in infants and pediatric patients caused by GAA deficiency. | Enzymes / Glucosidases / Glycogen Storage Disease Type II / Hydrolytic Lysosomal Glycogen-specific Enzyme |
| Tilactase | 102000.0 |  | A beta-D-galactosidase use to treat lactose intolerance. | Enzyme Preparations |
| Cipaglucosidase alfa | 99400.0 C4489H6796N1197O1298S32 | | A recombinant human acid alpha-glucosidase used to treat late-onset Pompe disease in adults. | Enzymes |
| Eftrenonacog alfa | 98000.0 | | A recombinant Factor IX used to treat and prevent bleeding in hemophilia B. | Amino Acids, Peptides, and Proteins / Biological Factors / Blood Coagulation Factors / Blood Proteins / Enzyme Precursors / Enzymes and Coenzymes / Globulins / Hemostatics / Immunoglobulin Constant Regions / Immunoglobulin Fragments / Immunoglobulins / Immunoproteins / Peptide Fragments / Peptides / Protein Precursors / Proteins / Recombinant Proteins / Serum Globulins |
| Abatacept | 92300.0 C3498H5458N922O1090S32 | | A disease-modifying antirheumatic drug (DMARD) used in the management of rheumatic conditions, such as rheumatoid or psoriatic arthritis, and for the prophylaxis of acute graft-versus-host disease. | Selective Immunosuppressants |
| Belatacept | 92300.0 C3508H5440N922O1096S32 | | A selective T-cell costimulation blocker used in the prophylaxis of organ rejection in adult patients receiving a kidney transplant. | Selective Immunosuppressants |
| Certolizumab pegol | 91000.0 C2115H3252N556O673S16 |  | A tumor necrosis factor (TNF) blocker used to treat a variety of autoimmune and autoinflammatory conditions like Crohn's disease, rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, axial spondyloarthritis, and plaque psoriasis. | Tumor necrosis factor alpha (TNF-alpha) inhibitors |
| Glucarpidase | 83000.0 C3670H5926N10114O1140S12 |  | A carboxypeptidase enzyme used to reduce plasma concentrations of methotrexate in patients with impaired renal function. | Detoxifying Agents for Antineoplastic Treatment |
| Sotatercept | 78000.0 C3448H5264N920O1058S42 | | A recombinant activin receptor fusion protein used to treat pulmonary arterial hypertension. | Immunoglobulin G |
| Luspatercept | 76000.0 | | An erythroid maturation agent used to treat anemia secondary to beta thalassemia, myelodysplastic syndromes, and neoplasms. | Hematinics |
| Idursulfase | 76000.0 C2654H4000N688O774S14 | | A purified lysosomal enzyme used as a replacement therapy for Hunter syndrome in pediatric and adult patients. | Enzymes / Hydrolytic Lysosomal Glycosaminoglycan-specific Enzyme |
| Protein S human | 75123.0 |  | A medication used for emergency reversal of coagulation factor deficiency in vitamin K antagonist therapy. | Anticoagulants / Blood Coagulation Factor Inhibitors / Blood Proteins / Glycoproteins |
| Albiglutide | 72970.0 C3232H5032N864O979S41 |  | A GLP-1 agonist used to manage type 2 diabetes mellitus. | Glucagon-like peptide-1 (GLP-1) analogues / Incretin Mimetics |
| Vestronidase alfa | 72562.0 | | A recombinant beta-glucuronidase used to treat mucopolysaccharidosis VII. | Enzymes |
| Eflapegrastim | 72000.0 | | A form of recombinant human granulocyte colony stimulating factor used to induce the production of granulocytes and lower infection risk after myelosuppressive therapy. | Amino Acids, Peptides, and Proteins / Biological Factors / Blood Proteins / Carbohydrates / Colony-Stimulating Factors / Cytokines / Globulins / Glycoconjugates / Glycoproteins / Granulocyte Colony-Stimulating Factors / Hematopoietic Cell Growth Factors / Immunoglobulin Constant Regions / Immunoglobulin Fragments / Immunoglobulins / Immunoproteins / Intercellular Signaling Peptides and Proteins / Leukocyte Growth Factor / Peptide Fragments / Peptides / Proteins / Serum Globulins |
Displaying drugs 126 - 150 of 407 in total