Recombinant Proteins

Name
Recombinant Proteins
Accession Number
DBCAT000097
Description

Proteins prepared by recombinant DNA technology.

Drugs
DrugDrug Description
Denileukin diftitoxA recombinant cytotoxic protein based on a combination of diphtheria toxin fragments and interleukin-2 used to treat cutaneous T-cell lymphoma by targeting the interleukin-2 receptor.
RasburicaseA recombinant form of urate-oxidase enzyme used to treat hyperuricemia following chemotherapy for leukemias and non-Hodgkin's lymphoma.
DesmoteplaseInvestigated for use/treatment in cerebral ischemia and strokes.
Maxy-G34Investigated for use/treatment in adverse effects (chemotherapy) and neutropenics.
OnerceptInvestigated for use/treatment in psoriasis and psoriatic disorders and crohn's disease.
PegsunerceptInvestigated for use/treatment in rheumatoid arthritis.
AlbiglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
DulaglutideA GLP-1 agonist used to manage type 2 diabetes mellitus.
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
Corifollitropin alfaA FSH analogue indicated for Controlled Ovarian Stimulation (COS) in combination with a GnRH antagonist for the development of multiple follicles in women participating in an Assisted Reproductive Technology (ART) program.
Turoctocog alfaAn antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency).
DulanerminDulanermin has been used in trials studying the treatment of Colorectal Cancer, Non-Hodgkin's Lymphoma, and Metastatic Colorectal Cancer.
Moroctocog alfaA recombinant Factor VIII used to treat hemophilia A to control bleeding.
Antihemophilic factor (recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
ElapegademaseA recombinant adenosine deaminase used to treat adenosine deaminase severe combined immune deficiency.
Turoctocog alfa pegolTuroctocog alfa pegol (N8-GP) is indicated for use in adults and children of all ages with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis in reducing the frequency of...
Eftrenonacog alfaA recombinant Factor IX used to treat and prevent bleeding in hemophilia B.
EndostarEndostar is under investigation for the treatment of Nasopharyngeal Carcinoma. Endostar has been investigated for the treatment of Non-small Cell Lung Cancer.
LuspaterceptAn erythroid maturation agent used to treat anemia secondary to beta thalassemia in patients requiring regular red blood cell transfusions.
Albutrepenonacog alfaA recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B.
TagraxofuspA CD123-directed cytotoxin used to treat plasmacytoid dendritic cell neoplasm.
PegilodecakinPegilodecakin is under investigation in clinical trial NCT03382912 (Study of Pegilodecakin (LY3500518) With Nivolumab Compared to Nivolumab Alone Second-line Tx in Participants With Metastatic Non-Small Cell Lung Cancer).
Talactoferrin alfaInvestigated for use/treatment in adverse effects (chemotherapy), cancer/tumors (unspecified), diabetic foot ulcers, lung cancer, solid tumors, and ulcers.
Rurioctocog alfa pegolNot Annotated
Drugs & Drug Targets
DrugTargetType
Denileukin diftitoxInterleukin-2 receptor subunit alphatarget
Denileukin diftitoxCytokine receptor common subunit gammatarget
Denileukin diftitoxInterleukin-2 receptor subunit betatarget
RasburicaseUric acidtarget
DesmoteplasePlasminogentarget
OnerceptTumor necrosis factortarget
AlbiglutideGlucagon-like peptide 1 receptortarget
DulaglutideGlucagon-like peptide 1 receptortarget
Corifollitropin alfaFollicle-stimulating hormone receptortarget
Turoctocog alfaCoagulation factor IXtarget
Turoctocog alfaCoagulation factor Xtarget
Turoctocog alfaProthrombintarget
Moroctocog alfaCoagulation factor Xtarget
Moroctocog alfaPhytanoyl-CoA dioxygenase, peroxisomaltarget
Moroctocog alfaCoagulation factor IXtarget
Moroctocog alfaAsialoglycoprotein receptor 2target
Moroctocog alfa78 kDa glucose-regulated proteintarget
Moroctocog alfaCalreticulintarget
Moroctocog alfaCalnexintarget
Moroctocog alfaProtein ERGIC-53target
Moroctocog alfaProlow-density lipoprotein receptor-related protein 1target
Moroctocog alfaMultiple coagulation factor deficiency protein 2target
Moroctocog alfavon Willebrand factortarget
Moroctocog alfaProthrombinenzyme
Moroctocog alfaVitamin K-dependent protein Cenzyme
Antihemophilic factor (recombinant), PEGylatedvon Willebrand factortarget
Antihemophilic factor (recombinant), PEGylatedvon Willebrand factorcarrier
ElapegademaseAdenosinetarget
Turoctocog alfa pegolVitamin K-dependent protein Cenzyme
Turoctocog alfa pegolCoagulation factor Xenzyme
Turoctocog alfa pegolCoagulation factor IXtarget
Turoctocog alfa pegolCoagulation factor Xtarget
Turoctocog alfa pegolProthrombintarget
Turoctocog alfa pegolvon Willebrand factortarget
Albutrepenonacog alfaCoagulation factor Xtarget
Albutrepenonacog alfaCoagulation factor VIIIenzyme
TagraxofuspInterleukin-3 receptor subunit alphatarget
TagraxofuspADP-ribosylation factor-like protein 2target