Phenothiazine Derivatives

Phenothiazine Derivatives
Accession Number

Not Available

ATC Classification
DrugDrug Description
AlimemazineAn antihistamine agent used to prevent and relieve allergic conditions which cause pruritus and other allergic skin conditions, including urticaria.
PromethazineA first-generation antihistamine used for the treatment of allergic conditions, nausea and vomiting, and motion sickness.
ThiethylperazineA drug used for the treatment of nausea and vomiting.
MethdilazineUsed for the symptomatic relief of hypersensitivity reactions and particularly for the control of pruritic skin disorders
MequitazineFor the treatment of Hay fever, urticaria (hives) and allergic rhinitis
IsothipendylA 1st generation histamine H1 antagonist primarily applied topically as an antipruritic.
ThiazinamNot Annotated
OxomemazineA phenothiazine derivative antihistamine indicated in the treatment of allergies.
HydroxyethylpromethazineNot Annotated
Drugs & Drug Targets
AlimemazineHistamine H1 receptortarget
PromethazineDopamine D2 receptortarget
PromethazineHistamine H1 receptortarget
PromethazineMuscarinic acetylcholine receptor M4target
PromethazineMuscarinic acetylcholine receptor M1target
PromethazineMuscarinic acetylcholine receptor M5target
PromethazineMuscarinic acetylcholine receptor M2target
PromethazineMuscarinic acetylcholine receptor M3target
PromethazineCytochrome P450 2D6enzyme
PromethazineCytochrome P450 2B6enzyme
PromethazineP-glycoprotein 1transporter
PromethazineCytochrome P450 2C9enzyme
PromethazineHistamine H2 receptortarget
PromethazineAlpha adrenergic receptortarget
PromethazineP2 Purinoceptorstarget
PromethazineVoltage-gated sodium channel alpha subunittarget
PromethazineVoltage-gated Potassium Channelstarget
PromethazineCanalicular multispecific organic anion transporter 2transporter
PromethazineMultidrug resistance-associated protein 4transporter
PromethazineSerum albumincarrier
ThiethylperazineDopamine D2 receptortarget
MethdilazineHistamine H1 receptortarget
MequitazineHistamine H1 receptortarget
MequitazineCytochrome P450 2D6enzyme
MequitazineCytochrome P450 3A4enzyme
IsothipendylHistamine H1 receptortarget