Infection caused by staphylococci (DBCOND0021394)

Identifiers

Synonyms
Infection Staphylococcal / Infections, Staphylococcal / Staphylococcal Infection / Staphy­lococcal infection / Staphylococcal Infections / Staphylococcal infection, unspecified site / Bacterial infection due to unspecified staphylococcus / Staphylococcal infection NOS / Staphylococcal infectious disease (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amikacin
An aminoglycoside used to treat infections caused by more resistant strains of Gram negative bacteria and some Gram positive bacteria.
Cloxacillin
An antibiotic agent used for the treatment of beta-hemolytic streptococcal and pneumococcal infections as well as staphylococcal infections.
Vancomycin
A glycopeptide antibiotic used to treat severe but susceptible bacterial infections such as MRSA (methicillin-resistant Staphylococcus aureus) infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT04257292
NExt-Generation Sequencing and Cell Culture-based Characterization of S. Aureus in Infective EndocarditisNo drug interventionsNot AvailableNot Availableunknown_status
NCT01160172
A Study to Evaluate the Safety, Reactogenicity and Immunogenicity of GSK Biologicals' Staphylococcal Investigational Vaccine in Healthy AdultsNo drug interventionsprevention1completed
NCT00279864
The Utility of Levofloxacin-Rifampin in the Therapy of Prosthetic Joint InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT00814151
MicroPhage S. Aureus / MSSA / MRSA Blood Culture Beta TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT00730028
Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureustreatment2completed
NCT01827358
Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infantsprevention2completed
NCT00735839
V710 Clinical Study in Healthy Male Japanese Subjects (V710-006) (COMPLETED)No drug interventionsprevention1completed
NCT02812446
Staphylokinase and ABO Group Phenotype: New Players in Staphylococcus Aureus Implant-associated Infections DevelopmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01592214
Study of the Safety and Local Tolerability of Intranasal Gel Formulations of XF-73No drug interventionstreatment1completed
NCT02899702
Effectiveness of Intravenous Immunoglobulins (IVIG) in Toxic Shock Syndromes in Childrentreatment4withdrawn
NCT00846105
Efficacy Study of Rapid Test to Prevent Hospital Transmission of Methicillin-Resistant Staphylococcus Aureus (MRSA)No drug interventionspreventionNot Availablecompleted
NCT00729937
Strategies Using Off-Patent Antibiotics for Methicillin Resistant S. Aureus "STOP MRSA"treatment2 / 3completed
NCT00770341
A Study of MK-3009 in Japanese Patients With Skin or Blood Stream Infections Caused by Methicillin-resistant Staphylococcus Aureus (MK-3009-002)treatment3completed
NCT00352612
Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infectionstreatment4completed
NCT02284555
Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)treatment4completed
NCT06479837
Modeling Host-Pathogen Interaction Using Lymphoid OrganoidsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00736554
What is the Prevalence of Methicillin-Resistant Staphylococcus Aureus in Skin and Soft Tissue Infections Presenting to the Emergency Departments of a Canadian Academic Health Care Center?No drug interventionsNot AvailableNot Availablecompleted
NCT00859677
Immunologic Predisposition of HIV Patients to Develop Methicillin-Resistant Staphylococcus Aureus (MRSA) Colonization and InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01364571
Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 YearsNo drug interventionsprevention1completed
NCT01447407
Effect of Adjuvant & Route of Administration on Safety & Immunogenicity of NDV-3 VaccineNo drug interventionsprevention1completed
NCT00211900
Evaluation of Manufacturing Lot of StaphVAXNo drug interventionsprevention3completed
NCT00211913
StaphVAX in Cardiovascular Surgery PatientsNo drug interventionsprevention3completed
NCT00646919
Preoperative Nasal Swabs From Pediatric PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00217841
Aurograb and Vancomycin in MRSA InfectionNo drug interventionseducational_counseling_training3completed
NCT01018641
An Evaluation Of Three Dose Levels Of 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) In Healthy AdultsNo drug interventionsprevention1completed
NCT02492958
SA4Ag Safety, Tolerability, and Immunogenicity Study in Japanese AdultsNo drug interventionsother2completed
NCT01273922
Safety and Immunogenicity Study of a Recombinant Protein Vaccine (NDV-3) Against S.Aureus and CandidaNo drug interventionsprevention1completed
NCT02971657
Bacterial Phenotype of Staphylococcus Aureus Has no Effect on Patients' Clinical Outcome in Orthopedic Device Related Bone InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01431326
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of CareNot AvailableNot Availablecompleted
NCT00211926
StaphVAX Immunogenicity in Orthopedic Implant PatientsNo drug interventionsprevention3completed
NCT00631566
Prospective Study of Methicillin-Resistant Staphylococcus Aureus (MRSA) Among HIV-Infected PersonstreatmentNot Availablecompleted
NCT02502474
Study of the Colonic Carriage of Staphylococcus Aureus in a Prospective Cohort of Patients Undergoing Endoscopic Screening for Digestive Cancer in the University Hospital of Saint-EtienneNo drug interventionsdiagnosticNot Availablecompleted
NCT00423982
Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplastytreatment4unknown_status
NCT00518076
Staphylococcus Aureus Carriers Students Nursing Oxacillin ResistantNo drug interventionsNot AvailableNot Availableunknown_status
NCT00130260
Evaluation of a Third and Fourth Dose of StaphVAX® in Adults With End-Stage Renal DiseaseNo drug interventionsprevention3terminated
NCT00113191
Safety and Efficacy of Veronate® Versus Placebo in Preventing Nosocomial Staphylococcal Sepsis in Premature InfantsNo drug interventionspreventionNot Availablecompleted
NCT00211991
Evaluation of Consistency of StaphVAX Manufacturing LotsNo drug interventionsprevention3completed
NCT00419991
Open Label Non-comparative Clinical Trial of Tigecycline in Patients With Catheter Infectiontreatment4completed
NCT00066989
Safety Study of an Intravenous Staphylococcus Aureus Immune Globulin (Human), [Altastaph] in Low-Birth-Weight-Neonatesprevention2completed
NCT00063089
Safety and Behavior of S. Aureus Immune Globulin Intravenous(Human), [Altastaph] in Patients With S. Aureus Bacteremia and Continuing Fevertreatment1 / 2completed
NCT05899140
Adjunctive Clindamycin for the Treatment of Skin and Soft Tissue Infections, a Randomized Controlled Trialtreatment4not_yet_recruiting
NCT02557568
Evaluation of an Algorithm for Identifying Persistent Nasal Staphylococcus Aureus Carriage in a Cohort of Healthy Volunteers and Patients Regularly Monitored at the CHU of Saint-EtienneNo drug interventionsdiagnosticNot Availablecompleted
NCT00303069
V710 First-In-Man (FIM) Study (V710-001)No drug interventionsprevention1completed
NCT00779246
Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital InfectionspreventionNot Availablecompleted
NCT02595112
Study of Staphylococcus Aureus Colonization of the Posterior Nasal Cavity in Patients Undergoing Otorhinolaryngologic SurgeryNo drug interventionsscreeningNot Availablecompleted
NCT00071214
Study to Evaluate the Effectiveness of StaphVAX in Adults on HemodialysisNo drug interventionsprevention3completed
NCT00501150
Oral Antibiotic Treatment at Home Instead of Intravenous Treatment in Hospital for Resistant Gram Positive InfectionstreatmentNot Availablecompleted
NCT00620984
Staphylococcus Aureus Carrier Status in Breastfeeding Mothers and Infants and the Risk of Lactation MastitisNo drug interventionsNot AvailableNot Availablecompleted
NCT04141787
Ceftriaxone as Home IV for Staph Infectionstreatment4unknown_status
NCT00156377
Prophylaxis With Intranasal Mupirocin for Prevention of S. Aureus Infectionsprevention4completed
NCT00509847
A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Bacteremia Due to S. Epidermidistreatment1 / 2withdrawn
NCT00368498
A Trial to Evaluate the Loading Dose Required to Achieve Therapeutic Serum Teicoplanin Concentration Timelytreatment4unknown_status
NCT02782078
Pharmacological Interaction of Rifampicin on Clindamycin in Staphylococcic Osteoarticular InfectionstreatmentNot Availablecompleted
NCT02640937
Biofilm Formation in Staphylococcus Epidermidis Associated Implant InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01144000
Daptomycin With Rifampin for Treatment of Staphylococcal Prosthetic Joint Infectiontreatment2unknown_status
NCT03915470
Effect of Exeporfinium Chloride (XF-73) Gel on Nasal S.Aureus in Patients at Risk of Post-op Staphylococcal InfectionNo drug interventionsprevention2completed
NCT00175370
Vancomycin Study: Treatment of Catheter Related Bloodstream Infection Caused by Coagulase Negative StaphylococcustreatmentNot Availablecompleted
NCT01643941
Evaluation of a Single Vaccination of One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) and a Single Dose Level of a 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) in Healthy Adults Aged 65 to <86 YearsNo drug interventionsprevention1completed
NCT02364596
Evaluation of a Single Vaccination With a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 YearsNo drug interventionsprevention1completed
NCT00211965
StaphVAX Immunogenicity and Safety in Orthopaedic Joint SurgeryNo drug interventionsprevention3completed
NCT00427076
Cotrimoxazole Versus Vancomycin for Invasive Methicillin-resistant Staphylococcus Aureus Infectionstreatment3completed
NCT00666276
Drug Use Investigation Of Zyvox (Linezolid) (Regulatory Post Marketing Commitment Plan)Not AvailableNot Availablecompleted
NCT00108160
Preventing Staphylococcal (Staph) Infectionprevention4completed
NCT04409392
Staphylococcus Lugdunensis Prosthetic Joint InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT03456544
Vancomycin-Associated Acute Kidney Injury: A Cross-Sectional Study From a Multi- Center in ChinaNot AvailableNot Availableunknown_status
NCT02664740
Standard Treatment Associated With Phage Therapy Versus Placebo for Diabetic Foot Ulcers Infected by S. AureusNo drug interventionstreatment1 / 2unknown_status
NCT01324440
Safety, Tolerability, and Immunogenicity of a Single Dose of Merck 0657nI Staphylococcus Aureus Vaccine With or Without Merck Aluminum Adjuvant (V710-002)No drug interventionsprevention1completed
NCT01196169
Daptomycin Use for Antimicrobial Prophylaxis in Methicillin Resistant Staphylococcus Aureus (MRSA) Colonized Adult Patients Undergoing Primary Elective Hip, Knee, or Shoulder Arthroplastyprevention4terminated