Epileptic seizure (DBCOND0025796)

Identifiers

Synonyms

Seizure, Epileptic / Epileptic Seizures / Seizures, Epileptic / Epileptic Seizure / Epileptic fit / Epileptic seizure (finding) / Epilepsy, unspecified, not intractable, without status epilepticus / Epilepsy, unspecified / Epilepsy and recurrent seizures / Epilepsy NOS / Seizure disorder (disorder) / Epilepsy / Epilepsy (disorder)

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Fludeoxyglucose (18F)	A radiopharmaceutical agent used for positron emission tomography (PET) imaging in oncology, cardiology, and neurology.	Hexokinase-1enzyme Solute carrier family 2, facilitated glucose transporter member 4transporter Solute carrier family 2, facilitated glucose transporter member 2transporter Solute carrier family 2, facilitated glucose transporter member 1transporter Solute carrier family 2, facilitated glucose transporter member 3transporter Solute carrier family 2, facilitated glucose transporter member 9transporter Solute carrier family 2, facilitated glucose transporter member 5transporter Solute carrier family 2, facilitated glucose transporter member 6transporter Solute carrier family 2, facilitated glucose transporter member 7transporter Solute carrier family 2, facilitated glucose transporter member 8transporter Solute carrier family 2, facilitated glucose transporter member 10transporter Solute carrier family 2, facilitated glucose transporter member 11transporter Solute carrier family 2, facilitated glucose transporter member 12transporter
Ganaxolone	A neuroactive steroid GABA-A receptor modulator used for the treatment of seizures associated with CDKL5 deficiency disorder (CDD).	GABA(A) Receptortarget Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Cytochrome P450 2B6enzyme Cytochrome P450 2C19enzyme Cytochrome P450 2D6enzyme
Midazolam	A short-acting benzodiazepine with rapid onset that is commonly used in seizures, anesthesia and anxiety disorders.	Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme UDP-glucuronosyltransferase 1A4enzyme Cytochrome P450 3A7enzyme GABA(A) Receptortarget GABA(A) Receptor Benzodiazepine Binding Sitetarget ATP-dependent translocase ABCB1transporter Albumincarrier Alpha-1-acid glycoprotein 1carrier Adenosine receptor A2atarget Excitatory amino acid transporter 2transporter UDP-glucuronosyltransferase 2B7enzyme UDP-glucuronosyltransferase 2B4enzyme Translocator proteintarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT06143241	Cognitive Function and Glymphatic System in Children with Epilepsy	No drug interventions	treatment	Not Available	completed
NCT02968966	Pathophysiology Based Therapy of Early Onset Epileptic Encephalopathies	No drug interventions	treatment	2	withdrawn
NCT05459597	Antiepileptic Drugs in Elderly Patients	No drug interventions	Not Available	Not Available	recruiting
NCT03123302	Our Anesthesia Experience During MRI Scan	No drug interventions	Not Available	Not Available	completed
NCT05567042	A Clinical Study of Epilepsy Localization and Prognosis Based on PET and Resting-state fMRI	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT04158531	REC2Stim as a Treatment for Refractory Epilepsy in the Primary Sensorimotor Cortex.	No drug interventions	treatment	Not Available	unknown_status
NCT03163719	Impact of Early Lactate Dosage Compared to CK for Diagnosis of a Suspected Seizure	No drug interventions	Not Available	Not Available	unknown_status
NCT03860467	Epileptic Seizures in Intensive Care Units	No drug interventions	Not Available	Not Available	completed
NCT00542802	Levetiracetam Versus Carbamazepine in Post-Stroke Late Onset Crisis	Carbamazepine Levetiracetam	treatment	3	unknown_status
NCT04291716	Study to Validate Novel Seizure-Detection Algorithm	No drug interventions	other	Not Available	unknown_status
NCT01351727	Epidemiologic Follow Up Study of Newly Diagnosed Epilepsy Among Seniors	No drug interventions	Not Available	Not Available	completed
NCT02304029	Usefulness of Sodium MRI in the Presurgical Assessment of Drug-resistant Partial Epilepsy	No drug interventions	diagnostic	Not Available	completed
NCT04204863	Status Epilepticus Population Study (STEPS)	No drug interventions	Not Available	Not Available	recruiting
NCT01450423	Physical Exercise in Subjects With Juvenile Myoclonic Epilepsy	No drug interventions	prevention	2	unknown_status
NCT05518578	Safety and Tolerability Study of SPN-817 in Adult Patients With Treatment Resistant Epilepsy	Huperzine A	treatment	2	recruiting
NCT04076449	Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy	No drug interventions	Not Available	Not Available	recruiting
NCT00297323	An Observational Study of the Safety of Topiramate in Adults and Children With Epilepsy	Topiramate	Not Available	Not Available	completed
NCT02424123	Is Protein S100B a Predictor of First-to-chronic Seizure Conversion in Adults?	No drug interventions	Not Available	Not Available	completed