NCT05356195
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT) treatment 3 recruiting NCT04987489
A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease treatment 2 recruiting NCT03655678
A Safety and Efficacy Study Evaluating CTX001 in Subjects With Transfusion-Dependent β-Thalassemia treatment 2 / 3 active_not_recruiting NCT06313398
Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling other 0 recruiting NCT06581627
A Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants treatment 1 recruiting NCT00001203
Deferoxamine for the Treatment of Hemochromatosis No drug interventions Not Available Not Available completed NCT00481221
Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter No drug interventions Not Available Not Available unknown_status NCT03651102
Efficacy and Safety of Low Dose Thalidomide in Transfusion Dependent Thalassemia treatment 2 / 3 completed NCT06213402
RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs) No drug interventions Not Available Not Available recruiting NCT02512679
Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells treatment 2 terminated NCT00456443
Invasive Infections in Children With Hemoglobinopathies No drug interventions Not Available Not Available completed NCT01319851
Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation treatment Not Available terminated NCT01250951
This Study Will Evaluate Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndromes (MDS), Thalassemia and Rare Anemia Types Having Transfusion-induced Iron Overload. treatment 4 completed NCT03170245
Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients No drug interventions Not Available Not Available completed NCT05255445
Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients No drug interventions Not Available Not Available completed NCT00427661
A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regimen No drug interventions treatment Not Available completed NCT00034528
Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia treatment 2 terminated NCT00735488
Sickle Cell Anemia Screening and Prevention in Northern Israel No drug interventions Not Available Not Available completed NCT00125788
L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia treatment 2 completed NCT02165007
Haploidentical Hematopoietic Stem Cell Transplantation treatment 1 active_not_recruiting NCT02995707
The Effective and Safety of Thalidomide in NTDT treatment 2 unknown_status NCT00586209
L-Glutamine Therapy for Sickle Cell Anemia treatment 2 terminated NCT04706585
Thalassemia Knowledge in Young People of Indonesia No drug interventions Not Available Not Available unknown_status NCT00153985
Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies treatment 2 completed NCT00459732
Zinc & Bone Health in Thalassemia: The Think Zinc Study No drug interventions treatment Not Available completed NCT05508932
Atrial Fibrillation in Beta-Thalassemia No drug interventions Not Available Not Available recruiting NCT02904252
The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospital No drug interventions Not Available Not Available completed NCT03692052
A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia treatment 2 active_not_recruiting NCT00520559
T2* in Transfusion Dependant Anemia, MI, LVF, Normal Patients No drug interventions Not Available Not Available completed NCT00872170
Sildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary Hypertension treatment 2 / 3 completed NCT01758042
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders No drug interventions treatment Not Available recruiting NCT00901199
Combined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload treatment 2 completed NCT01395199
Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major treatment 3 completed NCT01316549
Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation Not Available Not Available completed NCT00738413
Iron Balance Study of Deferasirox, Deferoxamine and the Combination of Both treatment 1 / 2 unknown_status NCT05736419
A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) treatment 2 recruiting NCT02504619
Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies No drug interventions treatment 1 / 2 terminated NCT01369719
Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload treatment Not Available completed NCT03825341
Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere treatment 2 terminated NCT03333486
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer treatment 2 active_not_recruiting NCT00327639
Factors Promoting Increased Rate and Success of Pregnancy in the Thalassemia Population in Toronto No drug interventions Not Available Not Available unknown_status NCT06210139
Pharmacotherapy Prescribing Pattern and the Adherence Level to Iron Chelation Therapy in Thalassemia No drug interventions Not Available Not Available completed NCT00872339
Assessment of Pain in People With Thalassemia No drug interventions Not Available Not Available completed NCT03728322
iHSCs With the Gene Correction of HBB Intervent Subjests With β-thalassemia Mutations No drug interventions treatment 0 unknown_status NCT01913548
Multi-Center Study of Iron Overload: Survey Study (MCSIO) No drug interventions Not Available Not Available completed NCT00661726
Evaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia treatment 2 completed NCT03095326
Pneumococcal Vaccination for Splenectomised Thalassemia Major Patients in Indonesia prevention 4 completed NCT02105766
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure treatment 2 recruiting NCT03032666
Sofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open Label Trial treatment 4 completed NCT05355766
Long-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients No drug interventions treatment 2 recruiting NCT01597765
Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients treatment Not Available completed NCT00004982
Combination Iron Chelation Therapy treatment 1 completed NCT03609827
Study of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients Not Available Not Available completed NCT01114776
Multi-Center Study of Iron Overload: Pilot Study No drug interventions Not Available Not Available completed NCT02133560
Use of Mobile Technology for Intensive Training in Medication Management No drug interventions health_services_research Not Available completed NCT00235391
Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload treatment 3 completed NCT03402191
L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension treatment 4 unknown_status NCT01549080
Study of Effects of YisuiShengxueGranules on Thalassemia No drug interventions Not Available Not Available completed NCT05790980
Assessment of Quality of Life in Thalassemic Patients at Assiut University Hospital: A Single-center Experience No drug interventions Not Available Not Available not_yet_recruiting NCT04208529
A Long-term Follow-up Study in Participants Who Received CTX001 other 3 enrolling_by_invitation NCT03609840
Study of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients Not Available Not Available completed NCT00735540
Clinical Diagnosis of Teenagers Admitted to Pediatric Departments No drug interventions Not Available Not Available completed NCT03342404
A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia treatment 2 completed NCT01419704
Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies No drug interventions treatment 1 / 2 withdrawn NCT02065869
Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant treatment 1 / 2 terminated NCT03919812
Immunomodulatory Vitamin D in Thalassemia No drug interventions treatment Not Available completed NCT04582110
The Role of OCTA in Patients Affected by Beta Thalassemia No drug interventions Not Available Not Available completed NCT06250595
European Rare Blood Disorders Platform (ENROL) No drug interventions Not Available Not Available recruiting NCT00000595
Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis treatment 2 completed NCT00730314
Unrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells No drug interventions treatment 1 / 2 completed NCT00707850
Pegasys® Plus Ribavirin in Thalassemic Patients With Hepatitis C Virus Infection treatment 4 completed NCT00712738
Oral Nifedipine to Treat Iron Overload treatment 1 completed NCT05326503
Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults With Thalassemia No drug interventions supportive_care Not Available unknown_status NCT00456690
Endocrine and Nutritional Assessment in B Thalassemia Major No drug interventions supportive_care Not Available completed NCT03165864
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 702843 Administered Subcutaneously to Healthy Volunteers treatment 1 completed NCT04614779
Long-term Clinical Study of CN128 in Thalassemia Patients No drug interventions treatment 2 completed NCT03935633
Short-term Clinical Study of CN128 in Thalassemia Patients No drug interventions treatment 1 completed NCT00872833
Assessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions No drug interventions Not Available Not Available completed NCT00971698
The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia No drug interventions Not Available Not Available completed NCT03392298
Study on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy Anemia treatment 4 unknown_status NCT01048905
Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension treatment 2 completed NCT00669305
Bone Marrow for Hemoglobinopathy Research No drug interventions Not Available Not Available completed NCT01935661
A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients. No drug interventions Not Available Not Available unknown_status NCT04398628
ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders No drug interventions Not Available Not Available recruiting NCT03513328
Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation treatment 1 / 2 completed NCT03374111
Colla Corii Asini Treating Anemia in Pregnant Women With Thalassemia(Presenting the Syndrome of Blood Deficiency) treatment 4 unknown_status NCT01911871
Multicenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations No drug interventions Not Available Not Available completed NCT00000588
Chelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone No drug interventions treatment 2 completed NCT00502788
Evaluating the Safety of Two Medications to Treat Hepatitis C in People With Thalassemia (The HepC Study) treatment 2 completed NCT03673085
Clinical Study of CN128 in Thalassemia Patients No drug interventions treatment 1 completed NCT00176852
Stem Cell Transplant for Hemoglobinopathy treatment 2 / 3 completed NCT02386800
CINC424A2X01B Rollover Protocol treatment 4 recruiting NCT04310059
Effect of Folic Acid Supplementation in Pregnant Women Having Thalassaemia Trait No drug interventions prevention Not Available not_yet_recruiting NCT00346242
Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events prevention 4 completed NCT03733249
Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study treatment 1 / 2 terminated NCT00040417
Bone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies treatment 2 terminated NCT02772016
Therapeutic Effect of Colla Corii Asini on Improving Anemia and Hemoglobin Composition in Pregnant Women With Thalassemia No drug interventions treatment 0 unknown_status NCT00789516
The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation No drug interventions Not Available Not Available completed NCT05477563
Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease treatment 3 recruiting NCT01905774
Renal Function Among Thalassemia Patients Treated by a Oral Chelator Deferasirox Not Available Not Available completed NCT00972231
Iron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia No drug interventions Not Available Not Available completed NCT03249831
A Blood Stem Cell Transplant for Sickle Cell Disease treatment 1 active_not_recruiting NCT00957931
Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs treatment 2 completed NCT01534676
Effects of Transfusion of Older Stored Red Cells No drug interventions treatment Not Available terminated NCT06058260
Assessment of Cognitive Function and Quality of Life in Thalassemic Children at Sohag University Hospital No drug interventions Not Available Not Available not_yet_recruiting NCT01158794
Genes Influencing Iron Overload State No drug interventions Not Available Not Available completed NCT05389891
Hemoglobinopathy Nursing Program and Pediatric Nursing Students No drug interventions treatment Not Available completed NCT00971880
Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects No drug interventions Not Available Not Available completed NCT01772680
Zinc and Diabetes in Patients With Thalassemia: a Pilot Study No drug interventions other Not Available completed NCT00744692
Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders treatment 1 completed NCT03117192
Zinc Supplementation on Cellular Immunity in Thalassemia Major prevention 4 completed NCT00578292
Allogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemia, THALLO treatment Not Available terminated NCT02065492
Amlodipine for Myocardial Iron in Thalassemia prevention 2 / 3 completed NCT03184844
The Effective and Safety of Thalidomide in TI treatment 2 unknown_status NCT00661804
Evaluating People With Thalassemia: The Thalassemia Longitudinal Cohort (TLC) Study No drug interventions Not Available Not Available completed NCT03715972
Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia Not Available Not Available completed NCT00040469
Bone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies treatment 2 terminated NCT03367546
Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases No drug interventions treatment 2 terminated NCT01443312
Demographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia Intermedia No drug interventions Not Available Not Available completed NCT03609814
Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT) Not Available Not Available completed NCT05529550
Assessment of Nutritional Status and Role of Insulin-like Growth Factor-1 in Children No drug interventions Not Available Not Available completed NCT00000623
Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN) Not Available Not Available completed