Open Heart Surgery (DBCOND0046365)

Identifiers

Synonyms

Open-heart Surgery / Open heart surgery / Open heart surgery (procedure) / Operation on heart (procedure) / Cardiac operation / Cardiac Surgical Procedures / Cardiac operation NOS

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Magnesium chloride	An ionic compound and source of magnesium used for electrolyte replenishment and conditions associated with magnesium deficiencies.	No drug targets
Potassium chloride	A potassium salt used to treat hypokalemia.	Solute carrier family 12 member 2target Solute carrier family 12 member 1target Solute carrier family 12 member 5target Solute carrier family 12 member 6target Solute carrier family 12 member 7target Solute carrier family 12 member 4target Solute carrier family 12 member 2transporter Solute carrier family 12 member 1transporter Solute carrier family 12 member 5transporter Solute carrier family 12 member 6transporter Solute carrier family 12 member 7transporter Solute carrier family 12 member 4transporter
Procaine	A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.	Sodium channel protein type 10 subunit alphatarget Glutamate receptor ionotropic, NMDA 3Atarget 5-hydroxytryptamine receptor 3Atarget Sodium-dependent dopamine transportertarget Neuronal acetylcholine receptor subunit alpha-2target Cholinesteraseenzyme DNA (cytosine-5)-methyltransferase 1target Calcium-activated potassium channeltarget Cytosolic phospholipase A2target 60 kDa lysophospholipasetarget Monoamine oxidasetarget Sodium-dependent dopamine transportertransporter Sodium-dependent noradrenaline transportertransporter Sodium-dependent serotonin transportertransporter DNA (cytosine-5)-methyltransferase 3Atarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT05316207	Tele-Nursing Follow-Up After Open Heart Surgery	No drug interventions	prevention	Not Available	completed
NCT05222256	Comparison Between Levosimendan and Adrenaline in CABG Patients	Epinephrine Levosimendan	treatment	Not Available	unknown_status
NCT06168799	Ilofotase Alfa for Prevention of Renal Damage After Cardiac Surgery	Recombinant human alkaline phosphatase	treatment	2	recruiting
NCT03955536	Comparison of the Effects of Different Physiotherapy and Rehabilitation Methods on Open Heart Surgery	No drug interventions	treatment	Not Available	unknown_status
NCT03806413	Post-surgical Delirium in Patients Undergoing Open Heart Surgery.	No drug interventions	Not Available	Not Available	not_yet_recruiting
NCT03106818	Postoperative Pain Alleviation in Open Heart Surgery	Acetaminophen Bupivacaine Ketorolac Magnesium sulfate	treatment	Not Available	completed
NCT05441358	Assessment of Platelet Function in Patients Undergoing Open Heart Surgery	No drug interventions	Not Available	Not Available	unknown_status
NCT05063370	Levosimendan in Patients With Impaired Right Ventricular Function Undergoing Cardiac Surgery	Levosimendan	treatment	2	unknown_status
NCT00569855	Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery	Phenoxybenzamine	treatment	2	completed
NCT05715060	Sternal Closure in Children After Cardiac Surgery	No drug interventions	other	Not Available	not_yet_recruiting
NCT01069562	Closed Loop Isoflurane Administration With Bispectral Index in Open Heart Surgery	No drug interventions	Not Available	Not Available	completed
NCT03105089	Effect of Cardiac Preconditioning Upon the Inotrope Score	No drug interventions	prevention	Not Available	completed
NCT04213040	Procalcitonin and Postoperative Outcome After Open-heart Surgery	No drug interventions	Not Available	Not Available	completed
NCT04670367	The Effects of Baduanjin Exercise on Meridian Energy and Heart Rate Variability in Patients Undergoing Cardiac Sugery	No drug interventions	prevention	Not Available	unknown_status
NCT06436872	The Effect of Informing the Relatives of Patients Undergoing Open Heart Surgery	No drug interventions	supportive_care	Not Available	completed
NCT05932368	Early Evaluation After Cardiac Surgery	No drug interventions	Not Available	Not Available	completed
NCT05522712	Acapella Versus Incentive Spirometer on Cardiopulmonary Fitness After Heart Valve Surgery.	No drug interventions	treatment	Not Available	unknown_status
NCT04486690	Neuroprotection During Open Heart Surgery	Ketamine Propofol	supportive_care	3	completed
NCT06203184	The Effect of Video Game-Based Exercises After Open Heart Surgery	No drug interventions	treatment	Not Available	recruiting
NCT06165861	The Effect of Using Virtual Reality Glasses on Surgical Fear and Anxiety	No drug interventions	supportive_care	Not Available	completed
NCT06195592	Development of Delirium in Patients Undergoing Open-Heart Surgery	No drug interventions	Not Available	Not Available	active_not_recruiting
NCT05149235	Gaming Technology and Cardiac Rehabilitation	No drug interventions	treatment	Not Available	completed
NCT03799965	The Effect of Advanced Improvement Program (ERAS) on Postoperative Outcomes in Patients Undergoing Open Heart Surgery	No drug interventions	other	Not Available	unknown_status
NCT04506762	Benefit of Peri-operative Bilateral ESP Catheters for Enhanced Recovery for Cardiac Surgery (ERCS)	No drug interventions	supportive_care	Not Available	terminated
NCT06551714	The Effect of Neurophysiological Facilitation Techniques on Health Parameters in Early Stages After Open Heart Surgery	No drug interventions	treatment	Not Available	recruiting