Refractory Status Epilepticus (DBCOND0062120)
Identifiers
- Synonyms
- Refractory Status epilepticus
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Clobazam A benzodiazepine used as adjunct treatment in seizures associated with Lennox-Gastaut syndrome.- Cytochrome P450 2C19enzyme
- Cytochrome P450 3A4enzyme
- Cytochrome P450 2B6enzyme
- Cytochrome P450 2C18enzyme
- ATP-dependent translocase ABCB1transporter
- GABA(A) Receptortarget
- Cytochrome P450 2D6enzyme
- GABA(A) Receptor Benzodiazepine Binding Sitetarget
- Albumincarrier
- Alpha-1-acid glycoprotein 1carrier
- Cytochrome P450 2C9enzyme
- UDP-glucuronosyltransferase 1A4enzyme
- UDP-glucuronosyltransferase 1-6enzyme
- UDP-glucuronosyltransferase 2B4enzyme
- UDP-glucuronosyltransferase 1A1enzyme
- Cytochrome P450 1A2enzyme
- Cytochrome P450 2C8enzyme
- Cytochrome P450 3A5enzyme
- Cytochrome P450 3A7enzyme
- Gamma-aminobutyric acid receptor subunit alpha-1target
- Gamma-aminobutyric acid receptor subunit gamma-3target
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT05830864 Multicenter Retrospective Study of Isoflurane in Refractory and Super-Refractory Status Epilepticus Not Available Not Available recruiting NCT05684978 Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus other 4 not_yet_recruiting NCT01796574 Ketogenic Diet for Refractory Status Epilepticus No drug interventions treatment Not Available completed NCT04333082 Refractory Status Epilepticus Treatment: Quality and Efficacy of Coma Induction No drug interventions Not Available Not Available completed NCT05851391 buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest No drug interventions treatment 2 recruiting NCT06344338 Application of tDCS Stimulation in Controlling Refractory Status Epilepticus No drug interventions treatment Not Available recruiting NCT05934903 Feasibility Study: tDCS for Treatment of Refractory Status Epilepticus No drug interventions other Not Available recruiting NCT05814523 To Evaluate the Efficacy, Safety, and Tolerability of Intravenous Ganaxolone Added to Standard of Care in Refractory Status Epilepticus (RSE) treatment 3 withdrawn