Schizoaffective Disorders

Also known as: Schizoaffective disorder / Schizophrenia schizoaffective / Schizoaffective psychosis / Schizo-affective type schizophrenia

Drug	Drug Name	Drug Description
DB00363	Clozapine	An antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients.
DB01267	Paliperidone	An atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.

Drug	Drug Name	Target	Type
DB00363	Clozapine	Dopamine D4 receptor	target
DB00363	Clozapine	Histamine H1 receptor	target
DB00363	Clozapine	Dopamine D2 receptor	target
DB00363	Clozapine	Neuron-specific vesicular protein calcyon	target
DB00363	Clozapine	Histamine H4 receptor	target
DB00363	Clozapine	5-hydroxytryptamine receptor 2A	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1A	target
DB00363	Clozapine	5-hydroxytryptamine receptor 2C	target
DB00363	Clozapine	Dopamine D1 receptor	target
DB00363	Clozapine	Cytochrome P450 1A2	enzyme
DB00363	Clozapine	Cytochrome P450 2D6	enzyme
DB00363	Clozapine	Dopamine D3 receptor	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M1	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M2	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M3	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M4	target
DB00363	Clozapine	Muscarinic acetylcholine receptor M5	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1B	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1D	target
DB00363	Clozapine	5-hydroxytryptamine receptor 1E	target
DB00363	Clozapine	5-hydroxytryptamine receptor 3A	target
DB00363	Clozapine	5-hydroxytryptamine receptor 6	target
DB00363	Clozapine	5-hydroxytryptamine receptor 7	target
DB00363	Clozapine	Alpha-1A adrenergic receptor	target
DB00363	Clozapine	Alpha-1B adrenergic receptor	target
DB00363	Clozapine	Alpha-2A adrenergic receptor	target
DB00363	Clozapine	Alpha-2B adrenergic receptor	target
DB00363	Clozapine	Alpha-2C adrenergic receptor	target
DB00363	Clozapine	Cytochrome P450 2C9	enzyme
DB00363	Clozapine	P-glycoprotein 1	transporter
DB00363	Clozapine	Cytochrome P450 3A4	enzyme
DB00363	Clozapine	Cytochrome P450 2C19	enzyme
DB00363	Clozapine	Dimethylaniline monooxygenase [N-oxide-forming] 3	enzyme
DB00363	Clozapine	UDP-glucuronosyltransferase 1-4	enzyme
DB00363	Clozapine	Cytochrome P450 1A1	enzyme
DB00363	Clozapine	Cytochrome P450 2A6	enzyme
DB00363	Clozapine	Cytochrome P450 2C8	enzyme
DB00363	Clozapine	Glutathione S-transferase P	target
DB01267	Paliperidone	Dopamine D2 receptor	target
DB01267	Paliperidone	5-hydroxytryptamine receptor 2A	target
DB01267	Paliperidone	Histamine H1 receptor	target
DB01267	Paliperidone	Alpha-1A adrenergic receptor	target
DB01267	Paliperidone	Alpha-1B adrenergic receptor	target
DB01267	Paliperidone	Dopamine D3 receptor	target
DB01267	Paliperidone	Dopamine D4 receptor	target
DB01267	Paliperidone	Dopamine D1 receptor	target
DB01267	Paliperidone	Alpha-2A adrenergic receptor	target
DB01267	Paliperidone	Alpha-2B adrenergic receptor	target
DB01267	Paliperidone	Alpha-2C adrenergic receptor	target
DB01267	Paliperidone	5-hydroxytryptamine receptor 1A	target
DB01267	Paliperidone	5-hydroxytryptamine receptor 1D	target
DB01267	Paliperidone	5-hydroxytryptamine receptor 2C	target
DB01267	Paliperidone	5-hydroxytryptamine receptor 7	target
DB01267	Paliperidone	Cytochrome P450 3A4	enzyme
DB01267	Paliperidone	Cytochrome P450 2D6	enzyme
DB01267	Paliperidone	Cytochrome P450 3A5	enzyme
DB01267	Paliperidone	P-glycoprotein 1	transporter

Drug	Drug Name	Phase	Status	Count
DB00915	Amantadine	1	Completed	1
DB14185	Aripiprazole lauroxil	1	Completed	1
DB09128	Brexpiprazole	1	Completed	1
DB00470	Dronabinol	1	Completed	1
DB11726	Encenicline	1	Completed	1
DB14009	Medical Cannabis	1	Completed	1
DB00563	Methotrexate	1	Completed	1
DB01017	Minocycline	1	Recruiting	1
DB00745	Modafinil	1	Completed	1
DB00218	Moxifloxacin	1	Completed	1
DB00334	Olanzapine	1	Completed	2
DB00904	Ondansetron	1	Completed	1
DB00107	Oxytocin	1	Completed	1
DB00107	Oxytocin	1	Suspended	1
DB01267	Paliperidone	1	Completed	5
DB01224	Quetiapine	1	Completed	1
DB00734	Risperidone	1	Completed	5
DB00641	Simvastatin	1	Completed	1
DB06151	Acetylcysteine	1 / 2	Recruiting	1
DB01212	Ceftriaxone	1 / 2	Unknown Status	1
DB01404	Ginseng	1 / 2	Completed	1
DB00360	Sapropterin	1 / 2	Completed	1
DB00150	Tryptophan	1 / 2	Recruiting	1
DB06151	Acetylcysteine	2	Unknown Status	1
DB01238	Aripiprazole	2	Completed	1
DB01238	Aripiprazole	2	Terminated	1
DB06216	Asenapine	2	Completed	1
DB05687	BL-1020	2	Completed	1
DB03793	Benzoic acid	2	Unknown Status	1
DB06698	Betahistine	2	Completed	1
DB04888	Bifeprunox	2	Completed	3
DB09226	Brilaroxazine	2	Completed	1
DB09061	Cannabidiol	2	Active Not Recruiting	1
DB09061	Cannabidiol	2	Completed	1
DB00169	Cholecalciferol	2	Withdrawn	1
DB03929	D-Serine	2	Completed	1
DB03929	D-Serine	2	Unknown Status	2
DB00633	Dexmedetomidine	2	Recruiting	1
DB00783	Estradiol	2	Completed	3
DB05708	GTS-21	2	Completed	1
DB00674	Galantamine	2	Terminated	1
DB10989	Hepatitis A Vaccine	2	Completed	1
DB10993	Hepatitis B Vaccine (Recombinant)	2	Completed	1
DB00159	Icosapent	2	Completed	1
DB00186	Lorazepam	2	Completed	1
DB08815	Lurasidone	2	Completed	1
DB00939	Meclofenamic acid	2	Completed	1
DB01043	Memantine	2	Terminated	1
DB01183	Naloxone	2	Completed	1
DB00334	Olanzapine	2	Terminated	2
DB11133	Omega-3 fatty acids	2	Completed	1
DB00904	Ondansetron	2	Completed	1
DB01267	Paliperidone	2	Completed	1
DB01267	Paliperidone	2	Terminated	1
DB00652	Pentazocine	2	Completed	1
DB00686	Pentosan polysulfate	2	Completed	1
DB09286	Pipamperone	2	Completed	1
DB02789	Pregnenolone	2	Completed	1
DB00396	Progesterone	2	Completed	1
DB01224	Quetiapine	2	Terminated	1
DB00481	Raloxifene	2	Completed	1
DB06155	Rimonabant	2	Terminated	1
DB00734	Risperidone	2	Completed	1
DB00734	Risperidone	2	Terminated	1
DB00133	Serine	2	Completed	1
DB00641	Simvastatin	2	Completed	1
DB12422	Sulforaphane	2	Completed	1
DB00675	Tamoxifen	2	Completed	1
DB00577	Valaciclovir	2	Completed	1
DB01273	Varenicline	2	Completed	1
DB11094	Vitamin D	2	Withdrawn	1
DB00246	Ziprasidone	2	Completed	1
DB00909	Zonisamide	2	Terminated	1
DB00260	Cycloserine	2 / 3	Completed	1
DB00145	Glycine	2 / 3	Completed	1
DB08887	Icosapent ethyl	2 / 3	Completed	1
DB01043	Memantine	2 / 3	Recruiting	1
DB01224	Quetiapine	2 / 3	Completed	1
DB00246	Ziprasidone	2 / 3	Completed	1
DB00945	Acetylsalicylic acid	3	Unknown Status	1
DB00915	Amantadine	3	Completed	1
DB01238	Aripiprazole	3	Completed	3
DB01238	Aripiprazole	3	Terminated	2
DB06216	Asenapine	3	Completed	2
DB00307	Bexarotene	3	Withdrawn	1
DB00490	Buspirone	3	Completed	1
DB03929	D-Serine	3	Completed	2
DB00633	Dexmedetomidine	3	Completed	1
DB00783	Estradiol	3	Completed	1
DB00783	Estradiol	3	Recruiting	1
DB05076	Fenretinide	3	Withdrawn	1
DB00674	Galantamine	3	Completed	1
DB00502	Haloperidol	3	Completed	1
DB00186	Lorazepam	3	Completed	1
DB08815	Lurasidone	3	Completed	3
DB00331	Metformin	3	Completed	1
DB01017	Minocycline	3	Unknown Status	1
DB11062	Octisalate	3	Recruiting	1
DB09535	Octocrylene	3	Recruiting	1
DB00334	Olanzapine	3	Completed	6
DB00334	Olanzapine	3	Withdrawn	1
DB01267	Paliperidone	3	Completed	3
DB00413	Pramipexole	3	Unknown Status	1
DB01224	Quetiapine	3	Completed	2
DB01224	Quetiapine	3	Terminated	2
DB00481	Raloxifene	3	Recruiting	1
DB00481	Raloxifene	3	Unknown Status	1
DB00734	Risperidone	3	Completed	9
DB00734	Risperidone	3	Terminated	1
DB00641	Simvastatin	3	Completed	1
DB09321	Zinc oxide	3	Recruiting	1
DB00246	Ziprasidone	3	Completed	2
DB00246	Ziprasidone	3	Terminated	2
DB00909	Zonisamide	3	Completed	1
DB00659	Acamprosate	4	Completed	1
DB06594	Agomelatine	4	Completed	1
DB00437	Allopurinol	4	Completed	1
DB00915	Amantadine	4	Terminated	1
DB06288	Amisulpride	4	Completed	3
DB01238	Aripiprazole	4	Completed	10
DB01238	Aripiprazole	4	Terminated	1
DB06413	Armodafinil	4	Completed	1
DB00289	Atomoxetine	4	Completed	1
DB12867	Benperidol	4	Completed	1
DB09128	Brexpiprazole	4	Recruiting	1
DB12401	Bromperidol	4	Completed	1
DB01156	Bupropion	4	Completed	2
DB00477	Chlorpromazine	4	Completed	1
DB01068	Clonazepam	4	Withdrawn	1
DB00363	Clozapine	4	Completed	5
DB00363	Clozapine	4	Not Yet Recruiting	1
DB00363	Clozapine	4	Recruiting	1
DB00363	Clozapine	4	Terminated	1
DB00260	Cycloserine	4	Completed	1
DB00151	Cysteine	4	Completed	1
DB00843	Donepezil	4	Unknown Status	1
DB01175	Escitalopram	4	Completed	1
DB01276	Exenatide	4	Completed	1
DB00623	Fluphenazine	4	Completed	1
DB04842	Fluspirilene	4	Completed	1
DB00674	Galantamine	4	Completed	2
DB01018	Guanfacine	4	Unknown Status	1
DB00502	Haloperidol	4	Completed	5
DB04946	Iloperidone	4	Terminated	1
DB00030	Insulin human	4	Completed	1
DB04465	Lactose	4	Completed	1
DB04465	Lactose	4	Recruiting	1
DB14509	Lithium carbonate	4	Completed	1
DB04871	Lorcaserin	4	Terminated	1
DB00678	Losartan	4	Active Not Recruiting	1
DB08815	Lurasidone	4	Completed	1
DB01065	Melatonin	4	Completed	1
DB01043	Memantine	4	Recruiting	1
DB00331	Metformin	4	Completed	1
DB00331	Metformin	4	Terminated	1
DB00331	Metformin	4	Withdrawn	1
DB01017	Minocycline	4	Completed	1
DB00745	Modafinil	4	Completed	1
DB00745	Modafinil	4	Terminated	1
DB00704	Naltrexone	4	Completed	2
DB00184	Nicotine	4	Completed	3
DB00184	Nicotine	4	Recruiting	1
DB00334	Olanzapine	4	Completed	17
DB00334	Olanzapine	4	Withdrawn	1
DB11133	Omega-3 fatty acids	4	Completed	1
DB09539	Omega-3-acid ethyl esters	4	Completed	1
DB01267	Paliperidone	4	Completed	5
DB01267	Paliperidone	4	Unknown Status	1
DB12710	Perazine	4	Completed	1
DB00850	Perphenazine	4	Completed	2
DB01100	Pimozide	4	Completed	1
DB01278	Pramlintide	4	Completed	1
DB00175	Pravastatin	4	Completed	2
DB00860	Prednisolone	4	Terminated	1
DB01224	Quetiapine	4	Completed	10
DB01224	Quetiapine	4	Terminated	1
DB00481	Raloxifene	4	Completed	2
DB00481	Raloxifene	4	Recruiting	1
DB00980	Ramelteon	4	Completed	1
DB00734	Risperidone	4	Completed	20
DB00734	Risperidone	4	Not Yet Recruiting	1
DB00734	Risperidone	4	Terminated	2
DB01399	Salsalate	4	Completed	1
DB06144	Sertindole	4	Completed	1
DB00641	Simvastatin	4	Active Not Recruiting	1
DB00641	Simvastatin	4	Withdrawn	1
DB00391	Sulpiride	4	Completed	1
DB00966	Telmisartan	4	Completed	1
DB00679	Thioridazine	4	Completed	1
DB06273	Tocilizumab	4	Completed	1
DB00577	Valaciclovir	4	Completed	1
DB00313	Valproic acid	4	Completed	1
DB01273	Varenicline	4	Completed	2
DB01273	Varenicline	4	Recruiting	2
DB01273	Varenicline	4	Terminated	1
DB00246	Ziprasidone	4	Completed	8
DB01624	Zuclopenthixol	4	Completed	1
DB12537	1,2-Benzodiazepine	Not Available	Completed	1
DB06288	Amisulpride	Not Available	Completed	2
DB01238	Aripiprazole	Not Available	Completed	4
DB01238	Aripiprazole	Not Available	Terminated	2
DB00245	Benzatropine	Not Available	Terminated	1
DB11695	Carnosine	Not Available	Completed	1
DB01178	Chlormezanone	Not Available	Completed	1
DB00477	Chlorpromazine	Not Available	Completed	1
DB01239	Chlorprothixene	Not Available	Completed	1
DB00363	Clozapine	Not Available	Completed	2
DB00363	Clozapine	Not Available	Unknown Status	1
DB00975	Dipyridamole	Not Available	Completed	1
DB00153	Ergocalciferol	Not Available	Completed	1
DB00402	Eszopiclone	Not Available	Completed	1
DB00875	Flupentixol	Not Available	Completed	1
DB00623	Fluphenazine	Not Available	Completed	1
DB04842	Fluspirilene	Not Available	Completed	1
DB00502	Haloperidol	Not Available	Completed	2
DB00270	Isradipine	Not Available	Completed	1
DB00408	Loxapine	Not Available	Completed	1
DB01065	Melatonin	Not Available	Active Not Recruiting	1
DB00933	Mesoridazine	Not Available	Completed	1
DB01403	Methotrimeprazine	Not Available	Completed	1
DB00704	Naltrexone	Not Available	Completed	2
DB00184	Nicotine	Not Available	Completed	2
DB00334	Olanzapine	Not Available	Active Not Recruiting	1
DB00334	Olanzapine	Not Available	Completed	7
DB00334	Olanzapine	Not Available	Unknown Status	1
DB11133	Omega-3 fatty acids	Not Available	Completed	1
DB00107	Oxytocin	Not Available	Completed	2
DB01267	Paliperidone	Not Available	Completed	1
DB00850	Perphenazine	Not Available	Completed	1
DB01100	Pimozide	Not Available	Completed	1
DB01621	Pipotiazine	Not Available	Completed	1
DB01224	Quetiapine	Not Available	Completed	4
DB00734	Risperidone	Not Available	Active Not Recruiting	1
DB00734	Risperidone	Not Available	Completed	9
DB00734	Risperidone	Not Available	Terminated	2
DB00734	Risperidone	Not Available	Unknown Status	1
DB00734	Risperidone	Not Available	Withdrawn	1
DB04844	Tetrabenazine	Not Available	Completed	2
DB13557	Thiopropazate	Not Available	Completed	1
DB01622	Thioproperazine	Not Available	Completed	1
DB00679	Thioridazine	Not Available	Completed	1
DB01623	Thiothixene	Not Available	Completed	1
DB00831	Trifluoperazine	Not Available	Completed	1
DB11094	Vitamin D	Not Available	Completed	1
DB00246	Ziprasidone	Not Available	Completed	4
DB01624	Zuclopenthixol	Not Available	Completed	1