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Displaying results 41 - 50 of 69 in total
  1. Pathway

    Quinidine Action Pathway

    smpdb.ca/view/SMP0000323
    Drug action

    During the next phase, known as the plateau phase, calcium L-type channels (I-CaL) open and the resulting influx of calcium ions roughly balances the outward flow of potassium channels. … Membrane ion pumps, such as the sodium-potassium ATPase and sodium-calcium exchanger (NCX), maintain low intracellular sodium (5 mM) and calcium (100 nM) concentrations and high intracellular potassium

    Drugs: ATP · Quinidine · Potassium cation · Calcium
    Enzymes: Sodium/calcium exchanger 1, Voltage-dependent T-type calcium channel subunit alpha-1G
  2. Pathway

    Ethanol NMDA Antagonist Action Pathway

    smpdb.ca/view/SMP0126453
    Drug action

    This prevents the calcium channel from opening and allowing calcium into to the post-synaptic neuron. … With calcium unable to enter the neuron, the neuron cannot depolarize which stops the signal or makes it much more difficult to get a signal through the neurons.

    Drugs: L-Glutamine · Glutamic acid · Ethanol · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A
  3. Pathway

    Quinidine Action Pathway (New)

    smpdb.ca/view/SMP0126282
    Drug action

    Quinidine also reduces repolarizing K+ currents (IKr, IKs), the inward rectifier potassium current (IK1), and the transient outward potassium current Ito, as well as the L-type calcium current ICa and

    Drugs: Quinidine · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent T-type calcium channel subunit alpha-1G
  4. Indication

    Potassium deficiency

    go.drugbank.com/conditions/DBCOND0023015
    Drugs: Magnesium aspartate · Potassium gluconate · Sodium chloride · Sodium metabisulfite
  5. Indication

    Folate deficiency

    go.drugbank.com/conditions/DBCOND0015758
    Drugs: (6R)-Folinic acid · Ascorbic acid · Calcium citrate · Cyanocobalamin · Ferrous gluconate · Ferrous sulfate anhydrous +4 more
  6. Indication

    Lead Poisoning

    go.drugbank.com/conditions/DBCOND0027862
    Drugs: Calcium saccharate · Dimercaprol · Edetate calcium disodium anhydrous · Edetic acid · Penicillamine · Succimer
  7. Indication

    Hyperkalemia

    go.drugbank.com/conditions/DBCOND0003949
    Drugs: Albuterol · Calcium chloride · Calcium saccharate · Patiromer · Sodium bicarbonate · Sodium zirconium cyclosilicate +1 more
  8. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis. More specifically, folic acid is required by the body for the synthesis of purin...

    Mixtures: Calcium PNV, Calcium Folic Acid Plus D ChewableCategories: ferrous gluconate and folic acid
  9. Pathway

    Ethanol GABA Agonist Action Pathway

    smpdb.ca/view/SMP0125151
    Drug action

    Ethanol, commonly seen in the form of various alcohols as well as hand sanitizer, is a drug that is injected intrathecally. Ethanol's effects are mainly seen in the brain where it binds to many receptors. The main effects are seen by the...

    Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Ethanol · Calcium · Magnesium cation +3 more
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A
  10. Indication

    Iron Deficiency (ID)

    go.drugbank.com/conditions/DBCOND0132786
    Drugs: (6R)-Folinic acid · Ascorbic acid · Calcium citrate · Ferric carboxymaltose · Ferric hydroxide · Ferric maltol +19 more