Biogenic Polyamines

Biogenic Polyamines
Accession Number

Biogenic amines having more than one amine group. These are long-chain aliphatic compounds that contain multiple amino and/or imino groups. Because of the linear arrangement of positive charge on these molecules, polyamines bind electrostatically to ribosomes, DNA, and RNA.

DrugDrug Description
PutrescinePutrescine is a toxic diamine formed by putrefaction from the decarboxylation of arginine and ornithine. Putrescine is a solid. This compound belongs to the polyamines. These are compounds containing more...
CadaverineCadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
SpermineFor nutritional supplementation, also for treating dietary shortage or imbalance
GlutathionylspermidineNot Available
TrypanothioneNot Available
SpermidineSpermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and...
MDL72527Not Available
CGC-11047Investigated for use/treatment in lymphoma (unspecified), macular degeneration, prostate cancer, and solid tumors.
TrodusquemineInvestigated for use/treatment in obesity and diabetes mellitus type 2.
DiethylnorspermineInvestigated for use/treatment in renal cell carcinoma, pancreatic cancer, melanoma, and lung cancer.
Drugs & Drug Targets
PutrescineOrnithine decarboxylasetarget
PutrescineS-adenosylmethionine decarboxylase proenzymetarget
PutrescinePutrescine-binding periplasmic proteintarget
PutrescineSolute carrier family 22 member 4transporter
PutrescineBeta-1 adrenergic receptortarget
PutrescineBeta-2 adrenergic receptortarget
Cadaverine2-C-methyl-D-erythritol 4-phosphate cytidylyltransferasetarget
SpermineSpermine oxidasetarget
SpermineSpermine synthasetarget
SpermineOrnithine decarboxylasetarget
SpermineXanthine dehydrogenase/oxidaseenzyme
SpermineSolute carrier family 22 member 4transporter
SpermineSolute carrier family 22 member 1transporter
SpermineDiamine acetyltransferase 1enzyme
SpermineDiamine acetyltransferase 2enzyme
SpermineExtracellular calcium-sensing receptortarget
SpermineBeta-1 adrenergic receptortarget
SpermineBeta-2 adrenergic receptortarget
TrypanothioneTrypanothione reductasetarget
SpermidineThioredoxin reductase 1, cytoplasmictarget
SpermidineGentamicin 3'-acetyltransferasetarget
SpermidineSpermidine/putrescine-binding periplasmic proteintarget
SpermidineSolute carrier family 22 member 4transporter
SpermidineSolute carrier family 22 member 1transporter
SpermidineBeta-1 adrenergic receptortarget
SpermidineBeta-2 adrenergic receptortarget
MDL72527Spermine oxidasetarget
TrodusquemineTyrosine-protein phosphatase non-receptor type 1target
TrodusquemineSodium-dependent dopamine transportertarget
TrodusquemineSodium-dependent noradrenaline transportertarget